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Loss of Elp3 blocks intestinal tuft cell differentiation via an mTORC1-Atf4 axis Wathieu, Caroline; Lavergne, Arnaud; Xu, Xinyi; Rolot, Marion; Nemazanyy, Ivan; Shostak, Kateryna; El Hachem, Najla; Maurizy, Chloe; Leemans, Charlotte; Close, Pierre; Nguyen, Laurent; Desmet, Christophe; Tielens, Sylvia; Dewals, Benjamin G.; Chariot, Alain 分享 收藏
Valine aminoacyl-tRNA synthetase promotes therapy resistance in melanoma 缬氨酸氨酰tRNA合成酶促进黑色素瘤的治疗抵抗 El-Hachem, Najla; Leclercq, Marine; Susaeta Ruiz, Miguel; Vanleyssem, Raphael; Shostak, Kateryna; Koerner, Pierre-Rene; Capron, Coralie; Martin-Morales, Lorena; Roncarati, Patrick; Lavergne, Arnaud; Blomme, Arnaud; Turchetto, Silvia; Goffin, Eric; Thandapani, Palaniraja; Tarassov, Ivan; Nguyen, Laurent; Pirotte, Bernard; Chariot, Alain; Marine, Jean-Christophe; Herfs, Michael; Rapino, Francesca; Agami, Reuven; Close, Pierre 分享 收藏
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The Repressing Function of the Oncoprotein BCL-3 Requires CtBP, while Its Polyubiquitination and Degradation Involve the E3 Ligase TBLR1 癌蛋白BCL-3的抑制功能需要CtBP，而其多泛素化和降解涉及E3连接酶TBLR1 Keutgens, Aurore; Shostak, Kateryna; Close, Pierre; Zhang, Xin; Hennuy, Benoit; Aussems, Marie; Chapelle, Jean-Paul; Viatour, Patrick; Gothot, Andre; Fillet, Marianne; Chariot, Alain 分享 收藏
Elp3-mediated codon-dependent translation promotes mTORC2 activation and regulates macrophage polarization Elp3-mediated密码子依赖翻译促进mTORC2活化并调节巨噬细胞极化 Chen, Dawei; Nemazanyy, Ivan; Peulen, Olivier; Shostak, Kateryna; Xu, Xinyi; Tang, Seng Chuan; Wathieu, Caroline; Turchetto, Silvia; Tielens, Sylvia; Nguyen, Laurent; Close, Pierre; Desmet, Christophe; Klein, Sebastian; Florin, Alexandra; Buttner, Reinhard; Petrellis, Georgios; Dewals, Benjamin; Chariot, Alain 分享 收藏
THEM6-mediated reprogramming of lipid metabolism supports treatment resistance in prostate cancer 脂质代谢的THEM6-mediated重编程支持前列腺癌的治疗抵抗 Blomme, Arnaud; Peter, Coralie; Mui, Ernest; Blanco, Giovanny Rodriguez; An, Ning; Mason, Louise M.; Jamieson, Lauren E.; McGregor, Grace H.; Lilla, Sergio; Ntala, Chara; Patel, Rachana; Thiry, Marc; Kung, Sonia H. Y.; Leclercq, Marine; Ford, Catriona A.; Rushworth, Linda K.; McGarry, David J.; Mason, Susan; Repiscak, Peter; Nixon, Colin; Salji, Mark J.; Markert, Elke; MacKay, Gillian M.; Kamphorst, Jurre J.; Graham, Duncan; Faulds, Karen; Fazli, Ladan; Gleave, Martin E.; Avezov, Edward; Edwards, Joanne; Yin, Huabing; Sumpton, David; Blyth, Karen; Close, Pierre; Murphy, Daniel J.; Zanivan, Sara; Leung, Hing Y. 分享 收藏
The E3 ligase COP1 promotes ERα signaling and suppresses EMT in breast cancer Tang, Seng Chuan; Lion, Quentin; Peulen, Olivier; Chariot, Philippe; Lavergne, Arnaud; Mayer, Alice; Fuster, Paula Allepuz; Close, Pierre; Klein, Sebastian; Florin, Alexandra; Buettner, Reinhard; Nemazanyy, Ivan; Shostak, Kateryna; Chariot, Alain 分享 收藏
Downregulation of the FTO m6A RNA demethylase promotes EMT-mediated progression of epithelial tumors and sensitivity to Wnt inhibitors Jeschke, Jana; Collignon, Evelyne; Al Wardi, Clemence; Krayem, Mohammad; Bizet, Martin; Jia, Yan; Garaud, Soizic; Wimana, Zena; Calonne, Emilie; Hassabi, Bouchra; Morandini, Renato; Deplus, Rachel; Putmans, Pascale; Dube, Gaurav; Singh, Nitesh Kumar; Koch, Alexander; Shostak, Kateryna; Rizzotto, Lara; Ross, Robert L.; Desmedt, Christine; Bareche, Yacine; Rothe, Francoise; Lehmann-Che, Jacqueline; Duterque-Coquillaud, Martine; Leroy, Xavier; Menschaert, Gerben; Teixeira, Luis; Guo, Mingzhou; Limbach, Patrick A.; Close, Pierre; Chariot, Alain; Leucci, Eleonora; Ghanem, Ghanem; Yuan, Bi-Feng; Willard-Gallo, Karen; Sotiriou, Christos; Marine, Jean-Christophe; Fuks, Francois 分享 收藏
Wobble tRNA modification and hydrophilic amino acid patterns dictate protein fate Rapino, Francesca; Zhou, Zhaoli; Sanchez, Ana Maria Roncero; Joiret, Marc; Seca, Christian; El Hachem, Najla; Valenti, Gianluca; Latini, Sara; Shostak, Kateryna; Geris, Liesbet; Li, Ping; Huang, Gang; Mazzucchelli, Gabriel; Baiwir, Dominique; Desmet, Christophe J.; Chariot, Alain; Georges, Michel; Close, Pierre 分享 收藏
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Loss of tRNA-modifying enzyme Elp3 activates a p53-dependent antitumor checkpoint in hematopoiesis Rosu, Adeline; El Hachem, Najla; Rapino, Francesca; Rouault-Pierre, Kevin; Jorssen, Joseph; Somja, Joan; Ramery, Eve; Thiry, Marc; Nguyen, Laurent; Jacquemyn, Maarten; Daelemans, Dirk; Adams, Christopher M.; Bonnet, Dominique; Chariot, Alain; Close, Pierre; Bureau, Fabrice; Desmet, Christophe J. 分享 收藏
ITGBL1 is a new immunomodulator that favors development of melanoma tumors by inhibiting natural killer cells cytotoxicity (vol 20, 12, 2021) Cheli, Yann; Tulic, Meri K.; El Hachem, Najla; Nottet, Nicolas; Jacquel, Arnaud; Gesson, Maeva; Strub, Thomas; Bille, Karine; Picard-Gauci, Alexandra; Montaudie, Henri; Beranger, Guillaume E.; Passeron, Thierry; Close, Pierre; Bertolotto, Corine; Ballotti, Robert 分享 收藏
ITGBL1 is a new immunomodulator that favors development of melanoma tumors by inhibiting natural killer cells cytotoxicity Cheli, Yann; Tulic, Meri K.; El Hachem, Najla; Nottet, Nicolas; Jacquel, Arnaud; Gesson, Maeva; Strub, Thomas; Bille, Karine; Picard-Gauci, Alexandra; Montaudie, Henri; Beranger, Guillaume E.; Passeron, Thierry; Close, Pierre; Bertolotto, Corine; Ballotti, Robert 分享 收藏
The X-linked trichothiodystrophy-causing gene RNF113A links the spliceosome to cell survival upon DNA damage Shostak, Kateryna; Jiang, Zheshen; Charloteaux, Benoit; Mayer, Alice; Habraken, Yvette; Tharun, Lars; Klein, Sebastian; Xu, Xinyi; Hong Quan Duong; Vislovukh, Andrii; Close, Pierre; Florin, Alexandra; Rambow, Florian; Marine, Jean-Christophe; Buettner, Reinhard; Chariot, Alain 分享 收藏
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