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C

Conor R. Caffrey

university of california san diego

47H指数
189论文数
8.6K被引数
收录论文 98
发表时间
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Discovery of benzyl carbamate inhibitors of coronavirus Mpro enzymes from a legacy collection of cysteine protease inhibitors从半胱氨酸蛋白酶抑制剂的馆藏库中发现苯甲氧羰酰基抑制冠状病毒Mpro酶的抑制剂
errJOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY
IF5.4
err2025-12-31
err0
PREAI
errSa Magalhaes Serafim, Mateus; Kronenberger, Thales; Francisco, Karol R.; De Sousa Reis, Erik Vinicius; Goncalves De Oliveira, Ellen; Marcelino E Oliveira, Fernanda Kelly; Serraglio Fortes, Isadora; Maciel Fernandes, Thais Helena; Barbosa Da Silva, Elany; Fajtova, Pavla; Skinner, Danielle E.; Syed, Rafay O.; Lage De Siqueira-Neto, Jair; Poso, Antti; Fernandes Mota, Bruno Eduardo; Alves Coelho-dos-Reis, Jordana Grazziela; Santos Abrahao, Jonatas; Goncalves Maltarollo, Vinicius; O'donoghue, Anthony J.; Caffrey, Conor R.
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The Proteasome Inhibitors as a Potential Treatment for the Neglected Tropical Diseases
errQJM: An International Journal of Medicine
IF0
err2025-11-26
err0
PREAI
errWaad Elsayed; M.A. Moustafa; Hala Elwakil; Conor R. Caffrey; Thaiz R. Teixeira; Rasha Abdallah Meselhey
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Fat or flat? The impact of dipole moment vectors on non-covalent interactions between aromatic tags and macromolecules脂肪或扁平？偶极矩矢量对芳香标记物与高分子之间非共价相互作用的影响
errInorg. Chem. Front.
IF0
err2025-10-21
err0
errOAAI
errJosef Holub †; Adéla Jílková †; Carina Lemke †; Lorenzo Cianni †; Petra Spiwoková; Martin Horn; Christian Breuer; Adrian Leontovyč; Jiří Brynda; Helena Mertlíková-Kaiserová; Marta Chanová; Fernanda dos Reis Rocho; Carlos A. Montanari; Nelly El-Sakkary; Conor R. Caffrey; Michael Gütschow; Drahomír Hnyk; Michael Mareš; Jindřich Fanfrlík
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Discovery of small molecules with anthelmintic potential in the Medicines for Malaria Venture's COVID and Global Health Priority Boxes using an infrared-based assay for Caenorhabditis elegans motility在Medicines for Malaria Venture的COVID和全球健康优先药物箱中，通过基于红外线的Caenorhabditis elegans运动性测定法发现具有驱虫潜力的小分子
errBMC RESEARCH NOTES
IF1.7
err2025-10-06
err0
errOAAI
errSun, Yujie Uli; Liu, Lawrence J.; Caffrey, Conor R.
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Synthesis and in vitro anti-trypanosomal evaluation of quinolone hydrazide analogues喹诺酮酰肼类衍生物的合成及体外抗锥虫活性评价
errMedicinal Chemistry Research
IF3.1
err2025-10-01
err0
errOAAI
errPhelelisiwe S. Dube; Sarah Makgoba; Karol R. Francisco; Lesetja J. Legoabe; Conor R. Caffrey; Richard M. Beteck
err分享
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Aza-peptide aldehydes and ketones: synthesis and evaluation as human 20S proteasome inhibitors偶氮肽醛和酮：合成及其作为人20S蛋白酶体抑制剂的评估
errFUTURE MEDICINAL CHEMISTRY
IF3.4
err2025-10-01
err0
PREAI
errCorrigan, Thomas S.; Border, Sarah E.; Lotti Diaz, Leilani M.; Kasper, Kayla Q.; Noonchester, Abigail M.; Amer, Rasmiah; Kucway, Kayla S.; Fleisher, Michael; Fernandez, Joseph P.; Lovins, Alex R.; Serrano, Ana K.; Caffrey, Conor R.; O'Donoghue, Anthony J.; Benson, Don M.; Hadad, Christopher M.; Ekici, Ozlem Dogan
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Design; Synthesis; and Evaluation of Aza-Peptide Michael Acceptors as Human 20S Proteasome Inhibitors: Extension to the Prime Site设计、合成及评价作为人20S蛋白酶体抑制剂的氮杂肽Michael受体：向活性位点延伸
errACS Omega
IF4.3
err2025-07-16
err0
errOAAI
errSarah E. Border; Leilani M. Lotti Diaz; Rasmiah Amer; Abigail M. Noonchester; Kayla S. Kucway; Michael Fleisher; Joseph P. Fernandez; Alex R. Lovins; Thomas S. Corrigan; Ana K. Serrano; Conor R. Caffrey; Anthony J. O’Donoghue; Don M. Benson; Christopher M. Hadad; Özlem Doğan Ekici
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Identification of Substituted 4-Aminocinnolines as Broad-Spectrum Antiparasitic Agents
errACS INFECTIOUS DISEASES
IF3.8
err2025-02-12
err0
errOAAI
errSpaulding, Andrew; Sharma, Amrita; Giardini, Miriam A.; Hoffman, Benjamin; Bernatchez, Jean A.; Mccall, Laura-Isobel; Calvet, Claudia M.; Ackermann, Jasmin; Souza, Julia M.; Thomas, Diane; Millard, Caroline C.; Devine, William G.; Singh, Baljinder; Silva, Everton M.; Leed, Susan E.; Roncal, Norma E.; Penn, Erica C.; Erath, Jessey; Kumar, Gaurav; Sepulveda, Yadira; Garcia, Arnold; Rodriguez, Ana; El-Sakkary, Nelly; Sciotti, Richard J.; Campbell, Robert F.; Momper, Jeremiah D.; Mckerrow, James H.; Caffrey, Conor R.; Siqueira-Neto, Jair L.; Pollastri, Michael P.; Mensa-Wilmot, Kojo; Ferrins, Lori
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Carmaphycin B-Based Proteasome Inhibitors to Treat Human African Trypanosomiasis: Structure-Activity Relationship and In Vivo Efficacy基于Carmaphycin B的蛋白酶体抑制剂治疗人类非洲锥虫病: 构效关系和体内功效
errACS INFECTIOUS DISEASES
IF3.8
err2024-11-26
err0
errOAAI
errLiu, Lawrence J.; Francisco, Karol R.; Sun, Yujie Uli; Serafim, Mateus Sa Magalhaes; Amarasinghe, Dilini K.; Teixeira, Thaiz R.; Lucero, Bobby; Kronenberger, Thales; Elsayed, Waad; Elwakeel, Hala; Al-Hindy, Momen; Almaliti, Jehad; Gerwick, William H.; O'Donoghue, Anthony J.; Caffrey, Conor R.
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Clickable Probes for Pathogen Proteasomes: Synthesis and Applications
errACS OMEGA
IF4.3
err2024-08-02
err0
errOAAI
errLiu, Lawrence J.; Lucero, Bobby; Manriquez-Rodriguez, Cindy; Francisco, Karol R.; Teixeira, Thaiz R.; Yohannan, Darius J.; Ballatore, Carlo; Myers, Samuel A.; O'Donoghue, Anthony J.; Caffrey, Conor R.
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The Kavaratamides: Discovery of Linear Lipodepsipeptides from the Marine Cyanobacterium Moorena bouillonii Using a Comparative Chemogeographic Analysis
errJOURNAL OF NATURAL PRODUCTS
IF3.6
err2024-06-04
err2
errOAAI
errRyu, Byeol; Glukhov, Evgenia; Teixeira, Thaiz R.; Caffrey, Conor R.; Madiyan, Saranya; Joseph, Valsamma; Avalon, Nicole E.; Leber, Christopher A.; Naman, C. Benjamin; Gerwick, William H.
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Pharmacophore Virtual Screening Identifies Riboflavin as an Inhibitor of the Schistosome Cathepsin B1 Protease with Antiparasitic Activity
errACS OMEGA
IF4.3
err2024-05-30
err1
errOAAI
errCogo, Ramon M.; Pavani, Thais F. A.; Mengarda, Ana C. A.; Cajas, Rayssa A.; Teixeira, Thaina R.; Fukui-Silva, Lucas; Sun, Yujie Uli; Liu, Lawrence J.; Amarasinghe, Dilini K.; Yoon, Michael C.; Santos-Filho, Osvaldo A.; de Moraes, Josue; Caffrey, Conor R.; Rando, Daniela G. G.
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Nature-Inspired Gallinamides Are Potent Antischistosomal Agents: Inhibition of the Cathepsin B1 Protease Target and Binding Mode Analysis
errACS INFECTIOUS DISEASES
IF3.8
err2024-05-17
err3
errOAAI
errSpiwokova, Petra; Horn, Martin; Fanfrlik, Jindrich; Jilkova, Adela; Fajtova, Pavla; Leontovyc, Adrian; Houstecka, Radka; Bielikova, Lucia; Brynda, Jiri; Chanova, Marta; Mertlikova-Kaiserova, Helena; Caro-Diaz, Eduardo J. E.; Almaliti, Jehad; El-Sakkary, Nelly; Gerwick, William H.; Caffrey, Conor R.; Mares, Michael
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Tractable Quinolone Hydrazides Exhibiting Sub-Micromolar and Broad Spectrum Antitrypanosomal Activities
errCHEMMEDCHEM
IF3.4
err2024-02-23
err3
errOAAI
errChirwa, Kgothatso A.; Francisco, Karol R.; Dube, Phelelisiwe S.; Park, Hayoung; Legoabe, Lesetja J.; Teixeira, Thaiz Rodrigues; Caffrey, Conor R.; Beteck, Richard M.
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Design, Synthesis, and Evaluation of An Anti-trypanosomal [1,2,4]Triazolo[1,5-a]pyrimidine Probe for Photoaffinity Labeling Studies
errCHEMMEDCHEM
IF3.4
err2024-02-12
err1
errOAAI
errLucero, Bobby; Francisco, Karol R.; Varricchio, Carmine; Liu, Lawrence J.; Yao, Yuemang; Brancale, Andrea; Brunden, Kurt R.; Caffrey, Conor R.; Ballatore, Carlo
err分享
err收藏
Biomechanics of parasite migration within hosts
errTrends in Parasitology
IF6.6
err2024-02-01
err1
PREAI
errYeh, Yi-Ting; del Alamo, Juan C.; Caffrey, Conor R.
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Structure-Activity Relationships, Tolerability and Efficacy of Microtubule-Active 1,2,4-Triazolo[1,5-a]pyrimidines as Potential Candidates to Treat Human African Trypanosomiasis
errCHEMMEDCHEM
IF3.4
err2023-07-24
err5
errOAAI
errMonti, Ludovica; Liu, Lawrence J.; Varricchio, Carmine; Lucero, Bobby; Alle, Thibault; Yang, Wenqian; Bem-Shalom, Ido; Gilson, Michael; Brunden, Kurt R.; Brancale, Andrea; Caffrey, Conor R.; Ballatore, Carlo
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Protein-protein interactions: developing small-molecule inhibitors/stabilizers through covalent strategies
errTRENDS IN PHARMACOLOGICAL SCIENCES
IF19.9
err2023-07-01
err13
errOAAI
errLucero, Bobby; Francisco, Karol R.; Liu, Lawrence J.; Caffrey, Conor R.; Ballatore, Carlo
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err收藏
Perspective on Schistosomiasis Drug Discovery: Highlights from a Schistosomiasis Drug Discovery Workshop at Wellcome Collection, London, September 2022
errACS INFECTIOUS DISEASES
IF3.8
err2023-04-21
err16
errOAAI
errCaldwell, Nicola; Afshar, Rana; Baragana, Beatriz; Bustinduy, Amaya L.; Caffrey, Conor R. .; Collins, James J.; Fusco, Daniela; Garba, Amadou; Gardner, Mark; Gomes, Mireille; Hoffmann, Karl F.; Hsieh, Michael; Lo, Nathan C.; McNamara, Case W.; Nono, Justin Komguep; Padalino, Gilda; Read, Kevin D.; Roestenberg, Meta; Spangenberg, Thomas; Specht, Sabine; Gilbert, Ian H.
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Microtubule-Stabilizing 1,2,4-Triazolo[1,5-a]pyrimidines as Candidate Therapeutics for Neurodegenerative Disease: Matched Molecular Pair Analyses and Computational Studies Reveal New Structure-Activity Insights
errJOURNAL OF MEDICINAL CHEMISTRY
IF6.8
err2022-12-19
err10
errOAAI
errAlle, Thibault; Varricchio, Carmine; Yao, Yuemang; Lucero, Bobby; Nzou, Goodwell; Demuro, Stefania; Muench, Megan; Vuong, Khoa D.; Oukoloff, Killian; Cornec, Anne-Sophie; Francisco, Karol R.; Caffrey, Conor R.; Lee, Virginia M. -Y.; Smith III, Amos B.; Brancale, Andrea; Brunden, Kurt R.; Ballatore, Carlo
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研究方向

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合作学者
合作期刊
V
Virginia M.‐Y. Lee
H 指数: 200 · 论文数: 920
T
Todd R. Golub
H 指数: 176 · 论文数: 749
S
Shu Chien
H 指数: 133 · 论文数: 870
J
John P. Moore
H 指数: 132 · 论文数: 572
A
Andrej Săli
H 指数: 129 · 论文数: 685
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