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Structural heterogeneity and dynamics in the apical stem loop of s2m from SARS-CoV-2 Delta by an integrative NMR spectroscopy and MD simulation approach 通过整合核磁共振波谱学和分子动力学模拟方法研究SARS-CoV-2 Delta变异株中s2m蛋白顶端茎环的结构异质性和动力学 Martin, Maria A. Wirtz; Makowski, Joseph A.; Matzel, Tobias; Kensinger, Adam H.; Herr, Alexander; Richter, Christian; Jonker, Hendrik R. A.; Wacker, Anna; Evanseck, Jeffrey D.; Schwalbe, Harald 分享 收藏
Dissecting the Conformational Heterogeneity of Stem-Loop Substructures of the Fifth Element in the 5′-Untranslated Region of SARS-CoV-2 ( vol 146, pg 30139, 2024) 解析SARS-CoV-2 5′-非编码区第五元素茎环亚结构构象异质性 (卷 146, 页 30139, 2024) Mertinkus, Klara R.; Oxenfarth, Andreas; Richter, Christian; Wacker, Anna; Mata, Carlos P.; Carazo, Jose Maria; Schlundt, Andreas 分享 收藏
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Differential effects of the N-terminal helix of FGF8b on the activity of a small-molecule FGFR inhibitor in cell culture and for the extracellular domain of FGFR3c in solution Mineev, Konstantin S.; Hargittay, Bruno; Jin, Jing; Catapano, Claudia; Dietz, Marina S.; Segarra, Marta; Harwardt, Mark S.; Richter, Christian; Jonker, Hendrik R. A.; Saxena, Krishna; Sreeramulu, Sridhar; Heilemann, Mike; Acker-Palmer, Amparo; Schwalbe, Harald 分享 收藏
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Targeting the Main Protease (Mpro, nsp5) by Growth of Fragment Scaffolds Exploiting Structure-Based Methodologies Altincekic, Nadide; Joeres, Nathalie; Loehr, Frank; Richter, Christian; Ehrhardt, Claus; Blommers, Marcel J. J.; Berg, Hannes; Oeztuerk, Sare; Gande, Santosh L.; Linhard, Verena; Orts, Julien; Saad, Marie Jose Abi; Buetikofer, Matthias; Kaderli, Janina; Karlsson, B. Goeran; Brath, Ulrika; Hedenstroem, Mattias; Groebner, Gerhard; Sauer, Uwe H.; Perrakis, Anastassis; Langer, Julian; Banci, Lucia; Cantini, Francesca; Fragai, Marco; Grifagni, Deborah; Barthel, Tatjana; Wollenhaupt, Jan; Weiss, Manfred S.; Robertson, Angus; Bax, Adriaan; Sreeramulu, Sridhar; Schwalbe, Harald 分享 收藏
NMR 1H,19F-based screening of the four stem-looped structure 5_SL1-SL4 located in the 5′-untranslated region of SARS-CoV 2 RNA 基于1h，19f的NMR筛选位于传染性非典型肺炎CoV 2 RNA的5 ′-非翻译区的四个茎环结构5_SL1-SL4 Hymon, Daniel; Martins, Jason; Richter, Christian; Sreeramulu, Sridhar; Wacker, Anna; Ferner, Jan; Patwardhan, Neeraj N.; Hargrove, Amanda E.; Schwalbe, Harald 分享 收藏
Design, quality and validation of the EU-OPENSCREEN fragment library poised to a high-throughput screening collection Jalencas, Xavier; Berg, Hannes; Espeland, Ludvik Olai; Sreeramulu, Sridhar; Kinnen, Franziska; Richter, Christian; Georgiou, Charis; Yadrykhinsky, Vladyslav; Specker, Edgar; Jaudzems, Kristaps; Miletic, Tanja; Harmel, Robert; Gribbon, Phil; Schwalbe, Harald; Brenk, Ruth; Jirgensons, Aigars; Zaliani, Andrea; Mestres, Jordi 分享 收藏
Integrated NMR/Molecular Dynamics Determination of the Ensemble Conformation of a Thermodynamically Stable CUUG RNA Tetraloop 集成NMR/分子动力学确定热力学稳定的CUUG RNA Tetraloop的整体构象 Oxenfarth, Andreas; Kummerer, Felix; Bottaro, Sandro; Schnieders, Robbin; Pinter, Gyorgy; Jonker, Hendrik R. A.; Fuertig, Boris; Richter, Christian; Blackledge, Martin; Lindorff-Larsen, Kresten; Schwalbe, Harald 分享 收藏
The COVID19-NMR Consortium: A Public Report on the Impact of this New Global Collaboration Duchardt-Ferner, Elke; Ferner, Jan; Fuertig, Boris; Hengesbach, Martin; Richter, Christian; Schlundt, Andreas; Sreeramulu, Sridhar; Wacker, Anna; Weigand, Julia E.; Wirmer-Bartoschek, Julia; Schwalbe, Harald 分享 收藏
HIF1α-AS1 is a DNA:DNA:RNA triplex-forming lncRNA interacting with the HUSH complex Leisegang, Matthias S.; Bains, Jasleen Kaur; Seredinski, Sandra; Oo, James A.; Krause, Nina M.; Kuo, Chao-Chung; Guenther, Stefan; Cetin, Nevcin Senturk; Warwick, Timothy; Cao, Can; Boos, Frederike; Ponce, Judit Izquierdo; Haydar, Shaza; Bednarz, Rebecca; Valasarajan, Chanil; Fuhrmann, Dominik C.; Preussner, Jens; Looso, Mario; Pullamsetti, Soni S.; Schulz, Marcel H.; Jonker, Hendrik R. A.; Richter, Christian; Rezende, Flavia; Gilsbach, Ralf; Pflueger-Mueller, Beatrice; Wittig, Ilka; Grummt, Ingrid; Ribarska, Teodora; Costa, Ivan G.; Schwalbe, Harald; Brandes, Ralf P. 分享 收藏
Biofunctional Nanodot Arrays in Living Cells Uncover Synergistic Co-Condensation of Wnt Signalodroplets Philippi, Michael; Richter, Christian P.; Kappen, Marie; Watrinet, Isabelle; Miao, Yi; Runge, Mercedes; Jorde, Lara; Korneev, Sergej; Holtmannspoetter, Michael; Kurre, Rainer; Holthuis, Joost C. M.; Garcia, K. Christopher; Plueckthun, Andreas; Steinhart, Martin; Piehler, Jacob; You, Changjiang 分享 收藏
Comprehensive Fragment Screening of the SARS-CoV-2 Proteome Explores Novel Chemical Space for Drug Development SARS-CoV-2蛋白质组的综合片段筛选为药物开发探索新的化学空间 Berg, Hannes; Martin, Maria A. Wirtz; Altincekic, Nadide; Alshamleh, Islam; Bains, Jasleen Kaur; Blechar, Julius; Ceylan, Betul; de Jesus, Vanessa; Dhamotharan, Karthikeyan; Fuks, Christin; Gande, Santosh L.; Hargittay, Bruno; Hohmann, Katharina F.; Hutchison, Marie T.; Korn, Sophie Marianne; Krishnathas, Robin; Kutz, Felicitas; Linhard, Verena; Matzel, Tobias; Meiser, Nathalie; Niesteruk, Anna; Pyper, Dennis J.; Schulte, Linda; Trucks, Sven; Azzaoui, Kamal; Blommers, Marcel J. J.; Gadiya, Yojana; Karki, Reagon; Zaliani, Andrea; Gribbon, Philip; Almeida, Marcius da Silva; Anobom, Cristiane Dinis; Bula, Anna L.; Butikofer, Matthias; Caruso, Icaro Putinhon; Felli, Isabella Caterina; Da Poian, Andrea T.; de Amorim, Gisele Cardoso; Fourkiotis, Nikolaos K.; Gallo, Angelo; Ghosh, Dhiman; Gomes-Neto, Francisco; Gorbatyuk, Oksana; Hao, Bing; Kurauskas, Vilius; Lecoq, Lauriane; Li, Yunfeng; Mebus-Antunes, Nathane Cunha; Mompean, Miguel; Neves-Martins, Thais Cristtina; Ninot-Pedrosa, Marti; Pinheiro, Anderson S.; Pontoriero, Letizia; Pustovalova, Yulia; Riek, Roland; Robertson, Angus J.; Saad, Marie Jose Abi; Trevino, Miguel A.; Tsika, Aikaterini C.; Almeida, Fabio C. L.; Bax, Ad; Henzler-Wildman, Katherine; Hoch, Jeffrey C.; Jaudzems, Kristaps; Laurents, Douglas, V; Orts, Julien; Pierattelli, Roberta; Spyroulias, Georgios A.; Duchardt-Ferner, Elke; Ferner, Jan; Furtig, Boris; Hengesbach, Martin; Lohr, Frank; Qureshi, Nusrat; Richter, Christian; Saxena, Krishna; Schlundt, Andreas; Sreeramulu, Sridhar; Wacker, Anna; Weigand, Julia E.; Wirmer-Bartoschek, Julia; Wohnert, Jens; Schwalbe, Harald 分享 收藏
Global analysis of biosynthetic gene clusters reveals conserved and unique natural products in entomopathogenic nematode-symbiotic bacteria Shi, Yi-Ming; Hirschmann, Merle; Shi, Yan-Ni; Ahmed, Shabbir; Abebew, Desalegne; Tobias, Nicholas J.; Grun, Peter; Crames, Jan J.; Poeschel, Laura; Kuttenlochner, Wolfgang; Richter, Christian; Herrmann, Jennifer; Mueller, Rolf; Thanwisai, Aunchalee; Pidot, Sacha J.; Stinear, Timothy P.; Groll, Michael; Kim, Yonggyun; Bode, Helge B. 分享 收藏
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Four-color single-molecule imaging with engineered tags resolves the molecular architecture of signaling complexes in the plasma membrane Bellon, Junel Sotolongo; Birkholz, Oliver; Richter, Christian P.; Eull, Florian; Kenneweg, Hella; Wilmes, Stephan; Rothbauer, Ulrich; You, Changjiang; Walter, Mark R.; Kurre, Rainer; Piehler, Jacob 分享 收藏
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