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T

Thorsten Mielke

Max Planck Institute for Molecular Genetics
H指数:54
被引数:8,533

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Nuclear speckles enable processing of RNA from GC-rich isochores

核质小体能够处理GC富集同源等基序中的RNA

Cell
IF42.5
2026-02-250
OAAI
Michał Małszycki; Lisa Martina; İbrahim Avşar Ilık; Daniela Salgado Figueroa; Nirmalya Dasgupta; Menşura Feray Çoşar; Keun-Tae Kim; Gil Carraco; Beatrix Fauler; David Meierhofer; Thorsten Mielke; Hiroo Imai; Cantaş Alev; Ferhat Ay; Tuğçe Aktaş
Author Correction: A critical period of translational control during brain development at codon resolution

作者更正：在密码子分辨率下，大脑发育期间翻译调控的一个关键时期

Nature Structural & Molecular Biology
IF10.1
2025-08-270
OAAI
Dermot Harnett; Mateusz C. Ambrozkiewicz; Ulrike Zinnall; Alexandra Rusanova; Ekaterina Borisova; Amelie N. Drescher; Marta Couce-Iglesias; Gabriel Villamil; Rike Dannenberg; Koshi Imami; Agnieszka Münster-Wandowski; Beatrix Fauler; Thorsten Mielke; Matthias Selbach; Markus Landthaler; Christian M. T. Spahn; Victor Tarabykin; Uwe Ohler; Matthew L. Kraushar
Enhancer adoption by an LTR retrotransposon generates viral-like particles, causing developmental limb phenotypes

长末端重复序列逆转座子通过增强子获取产生类似病毒的颗粒，导致发育性肢体表型。

Nature Genetics
IF0
2025-07-090
OAAI
Juliane Glaser; Giulia Cova; Beatrix Fauler; Cesar A. Prada-Medina; Virginie Stanislas; Mai H. Q. Phan; Robert Schöpflin; Yasmin Aktas; Martin Franke; Guillaume Andrey; Natalia Bartzoka; Christina Paliou; Verena Laupert; Wing-Lee Chan; Lars Wittler; Thorsten Mielke; Stefan Mundlos
Structural mechanism of CRL4-instructed STAT2 degradation via a novel cytomegaloviral DCAF receptor
EMBO JOURNAL
IF8.3
2023-02-104
OA
Le-Trilling, Vu Thuy Khanh; Banchenko, Sofia; Paydar, Darius; Leipe, Pia Madeleine; Binting, Lukas; Lauer, Simon; Graziadei, Andrea; Klingen, Robin; Gotthold, Christine; Buerger, Joerg; Bracht, Thilo; Sitek, Barbara; Jan Lebbink, Robert; Malyshkina, Anna; Mielke, Thorsten; Rappsilber, Juri; Spahn, Christian M. T.; Voigt, Sebastian; Trilling, Mirko; Schwefel, David
T-REX17 is a transiently expressed non-coding RNA essential for human endoderm formation
ELIFE
IF0
2023-01-310
OA
Landshammer, Alexandro; Bolondi, Adriano; Kretzmer, Helene; Much, Christian; Buschow, Rene; Rose, Alina; Wu, Hua-Jun; Mackowiak, Sebastian D.; Braendl, Bjoern; Giesselmann, Pay; Tornisiello, Rosaria; Parsi, Krishna Mohan; Huey, Jack; Mielke, Thorsten; Meierhofer, David; Maehr, Rene; Hnisz, Denes; Michor, Franziska; Rinn, John L.; Meissner, Alexander
A critical period of translational control during brain development at codon resolution
NATURE STRUCTURAL & MOLECULAR BIOLOGY
IF10.1
2022-12-0821
OAAI
Harnett, Dermot; Ambrozkiewicz, Mateusz C.; Zinnall, Ulrike; Rusanova, Alexandra; Borisova, Ekaterina; Drescher, Amelie N.; Couce-Iglesias, Marta; Villamil, Gabriel; Dannenberg, Rike; Imami, Koshi; Munster-Wandowski, Agnieszka; Fauler, Beatrix; Mielke, Thorsten; Selbach, Matthias; Landthaler, Markus; Spahn, Christian M. T.; Tarabykin, Victor; Ohler, Uwe; Kraushar, Matthew L.
ARTICLE Alternative splicing of BUD13 determines the severity of a developmental disorder with lipodystrophy and progeroid features

文章BUD13的选择性剪接决定了具有脂肪营养不良和早衰症特征的发育障碍的严重程度

GENETICS IN MEDICINE
IF6.2
2022-09-012
OAAI
Kornak, Uwe; Saha, Namrata; Keren, Boris; Neumann, Alexander; Tavares, Ana Lisa Taylor; Piard, Juliette; Kopp, Johannes; Alves, Joao Guilherme Rodrigues; de los Santos, Miguel Rodriguez; El Choubassi, Naji; Ehmke, Nadja; Jaeger, Marten; Spielmann, Malte; Pantel, Jean Tori; Lejeune, Elodie; Fauler, Beatrix; Mielke, Thorsten; Hecht, Jochen; Meierhofer, David; Strom, Tim M.; Laugel, Vincent; Brice, Alexis; Mundlos, Stefan; Bertoli-Avella, Aida; Bauer, Peter; Heyd, Florian; Boute, Odile; Dupont, Juliette; Depienne, Christel; Van Maldergem, Lionel; Fischer-Zirnsak, Bjoern
Structures of active melanocortin-4 receptor-Gs-protein complexes with NDP-α-MSH and setmelanotide

具有ndp-α-msh和setmelanotide的活性melanocortin-4受体-Gs-蛋白复合物的结构

CELL RESEARCH
IF25.9
2021-09-2449
OAAI
Heyder, Nicolas A.; Kleinau, Gunnar; Speck, David; Schmidt, Andrea; Paisdzior, Sarah; Szczepek, Michal; Bauer, Brian; Koch, Anja; Gallandi, Monique; Kwiatkowski, Dennis; Buerger, Joerg; Mielke, Thorsten; Beck-Sickinger, Annette G.; Hildebrand, Peter W.; Spahn, Christian M. T.; Hilger, Daniel; Schacherl, Magdalena; Biebermann, Heike; Hilal, Tarek; Kuehnen, Peter; Kobilka, Brian K.; Scheerer, Patrick
Dnmt1 has de novo activity targeted to transposable elements
NATURE STRUCTURAL & MOLECULAR BIOLOGY
IF10.1
2021-06-1794
OAAI
Haggerty, Chuck; Kretzmer, Helene; Riemenschneider, Christina; Kumar, Abhishek Sampath; Mattei, Alexandra L.; Bailly, Nina; Gottfreund, Judith; Giesselmann, Pay; Weigert, Raha; Braendl, Bjoern; Giehr, Pascal; Buschow, Rene; Galonska, Christina; von Meyenn, Ferdinand; Pappalardi, Melissa B.; McCabe, Michael T.; Wittler, Lars; Giesecke-Thiel, Claudia; Mielke, Thorsten; Meierhofer, David; Timmermann, Bernd; Mueller, Franz-Josef; Walter, Joern; Meissner, Alexander

研究方向

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C.M.T. Spahn
H 指数:58论文数:206被引数:1.1万
J
Jörg Bürger
H 指数:23论文数:58被引数:1,947
B
Beatrix Fauler
H 指数:16论文数:36被引数:1.1万
J
J. Loerke
H 指数:23论文数:58被引数:2,374
T
Tarek Hilal
H 指数:14论文数:70被引数:1,060
R
Roland Beckmann
H 指数:84论文数:342被引数:2.0万
O
Otto Berninghausen
H 指数:65论文数:193被引数:1.2万
D
David Meierhofer
H 指数:41论文数:190被引数:5,387
D
Daniel N. Wilson
H 指数:78论文数:317被引数:1.8万
H
Hiroshi Yamamoto
H 指数:88论文数:1,100被引数:3.0万