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Visualizing the modification landscape of the human 60S ribosomal subunit at close to atomic resolution Wiechert, Franziska; Unbehaun, Anett; Sprink, Thiemo; Seibel, Helena; Buerger, Joerg; Loerke, Justus; Mielke, Thorsten; Diebolder, Christoph A.; Schacherl, Magdalena; Spahn, Christian M. T. 分享 收藏
Protein translation rate determines neocortical neuron fate 蛋白质翻译速率决定新皮质神经元命运 Borisova, Ekaterina; Newman, Andrew G.; Iglesias, Marta Couce; Dannenberg, Rike; Schaub, Theres; Qin, Bo; Rusanova, Alexandra; Brockmann, Marisa; Koch, Janina; Daniels, Marieatou; Turko, Paul; Jahn, Olaf; Kaplan, David R.; Rosario, Marta; Iwawaki, Takao; Spahn, Christian M. T.; Rosenmund, Christian; Meierhofer, David; Kraushar, Matthew L.; Tarabykin, Victor; Ambrozkiewicz, Mateusz C. 分享 收藏
Multimodal binding and inhibition of bacterial ribosomes by the antimicrobial peptides Api137 and Api88 抗菌肽Api137和Api88对细菌核糖体的多模式结合和抑制 Lauer, Simon M.; Reepmeyer, Maren; Berendes, Ole; Klepacki, Dorota; Gasse, Jakob; Gabrielli, Sara; Grubmueller, Helmut; Bock, Lars V.; Krizsan, Andor; Nikolay, Rainer; Spahn, Christian M. T.; Hoffmann, Ralf 分享 收藏
Transient disome complex formation in native polysomes during ongoing protein synthesis captured by cryo-EM Fluegel, Timo; Schacherl, Magdalena; Unbehaun, Anett; Schroeer, Birgit; Dabrowski, Marylena; Buerger, Joerg; Mielke, Thorsten; Sprink, Thiemo; Diebolder, Christoph A.; Schlippe, Yollete V. Guillen; Spahn, Christian M. T. 分享 收藏
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Structure of the actively translating plant 80S ribosome at 2.2 Å resolution Smirnova, Julia; Loerke, Justus; Kleinau, Gunnar; Schmidt, Andrea; Buerger, Joerg; Meyer, Etienne H.; Mielke, Thorsten; Scheerer, Patrick; Bock, Ralph; Spahn, Christian M. T.; Zoschke, Reimo 分享 收藏
Cryo-EM captures early ribosome assembly in action Cryo-em在行动中捕获早期核糖体组装 Qin, Bo; Lauer, Simon M. M.; Balke, Annika; Vieira-Vieira, Carlos H. H.; Buerger, Jorg; Mielke, Thorsten; Selbach, Matthias; Scheerer, Patrick; Spahn, Christian M. T.; Nikolay, Rainer 分享 收藏
Structural mechanism of CRL4-instructed STAT2 degradation via a novel cytomegaloviral DCAF receptor Le-Trilling, Vu Thuy Khanh; Banchenko, Sofia; Paydar, Darius; Leipe, Pia Madeleine; Binting, Lukas; Lauer, Simon; Graziadei, Andrea; Klingen, Robin; Gotthold, Christine; Buerger, Joerg; Bracht, Thilo; Sitek, Barbara; Jan Lebbink, Robert; Malyshkina, Anna; Mielke, Thorsten; Rappsilber, Juri; Spahn, Christian M. T.; Voigt, Sebastian; Trilling, Mirko; Schwefel, David 分享 收藏
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A critical period of translational control during brain development at codon resolution Harnett, Dermot; Ambrozkiewicz, Mateusz C.; Zinnall, Ulrike; Rusanova, Alexandra; Borisova, Ekaterina; Drescher, Amelie N.; Couce-Iglesias, Marta; Villamil, Gabriel; Dannenberg, Rike; Imami, Koshi; Munster-Wandowski, Agnieszka; Fauler, Beatrix; Mielke, Thorsten; Selbach, Matthias; Landthaler, Markus; Spahn, Christian M. T.; Tarabykin, Victor; Ohler, Uwe; Kraushar, Matthew L. 分享 收藏
Structures of active melanocortin-4 receptor-Gs-protein complexes with NDP-α-MSH and setmelanotide 具有ndp-α-msh和setmelanotide的活性melanocortin-4受体-Gs-蛋白复合物的结构 Heyder, Nicolas A.; Kleinau, Gunnar; Speck, David; Schmidt, Andrea; Paisdzior, Sarah; Szczepek, Michal; Bauer, Brian; Koch, Anja; Gallandi, Monique; Kwiatkowski, Dennis; Buerger, Joerg; Mielke, Thorsten; Beck-Sickinger, Annette G.; Hildebrand, Peter W.; Spahn, Christian M. T.; Hilger, Daniel; Schacherl, Magdalena; Biebermann, Heike; Hilal, Tarek; Kuehnen, Peter; Kobilka, Brian K.; Scheerer, Patrick 分享 收藏
Structural insights into Cullin4-RING ubiquitin ligase remodelling by Vpr from simian immunodeficiency viruses Banchenko, Sofia; Krupp, Ferdinand; Gotthold, Christine; Buerger, Joerg; Graziadei, Andrea; O'Reilly, Francis J.; Sinn, Ludwig; Ruda, Olga; Rappsilber, Juri; Spahn, Christian M. T.; Mielke, Thorsten; Taylor, Ian A.; Schwefel, David 分享 收藏
Snapshots of native pre-50S ribosomes reveal a biogenesis factor network and evolutionary specialization 天然pre-50S核糖体的快照揭示了生物发生因子网络和进化专业化 Nikolay, Rainer; Hilal, Tarek; Schmidt, Sabine; Qin, Bo; Schwefel, David; Vieira-Vieira, Carlos H.; Mielke, Thorsten; Buerger, Joerg; Loerke, Justus; Amikura, Kazuaki; Fluegel, Timo; Ueda, Takuya; Selbach, Matthias; Deuerling, Elke; Spahn, Christian M. T. 分享 收藏
Protein Synthesis in the Developing Neocortex at Near-Atomic Resolution Reveals Ebp1-Mediated Neuronal Proteostasis at the 60S Tunnel Exit Kraushar, Matthew L.; Krupp, Ferdinand; Harnett, Dermot; Turko, Paul; Ambrozkiewicz, Mateusz C.; Sprink, Thiemo; Imami, Koshi; Guennigmann, Manuel; Zinnall, Ulrike; Vieira-Vieira, Carlos H.; Schaub, Theres; Muenster-Wandowski, Agnieszka; Buerger, Joerg; Borisova, Ekaterina; Yamamoto, Hiroshi; Rasin, Mladen-Roko; Ohler, Uwe; Beule, Dieter; Mielke, Thorsten; Tarabykin, Victor; Landthaler, Markus; Kramer, Guenter; Vida, Imre; Selbach, Matthias; Spahn, Christian M. T. 分享 收藏
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The Axonal Membrane Protein PRG2 Inhibits PTEN and Directs Growth to Branches Brosig, Annika; Fuchs, Joachim; Ipek, Fatih; Kroon, Cristina; Schroetter, Sandra; Vadhvani, Mayur; Polyzou, Alexandra; Ledderose, Julia; van Diepen, Michiel; Holzhuetter, Hermann-Georg; Trimbuch, Thorsten; Gimber, Niclas; Schmoranzer, Jan; Lieberam, Ivo; Rosenmund, Christian; Spahn, Christian; Scheerer, Patrick; Szczepek, Michal; Leondaritis, George; Eickholt, Britta J. 分享 收藏