David H. Margulies - Publications, H-index & Citations

David H. Margulies

national institutes of health (nih) - usa

58H指数

341论文数

1.1W被引数

收录论文 77

发表时间

Foxp3 M370I mutation allows the activation of T effector programs in regulatory T cells

JOURNAL OF IMMUNOLOGY

IF3.4

2025-11-01

PREAI

Peng, Dingkang; Thornton, Angela M.; Tison, Kole; Yoon, Sunghwan; Gillen, Joseph G.; Chung, Hyunwoo; Chen, Xi; Cao, Yaqiang; Zhao, Keji; Liu, Chengyu; Jiang, Jiansheng; Margulies, David H.; Nita-Lazar, Aleksandra; Shevach, Ethan M.; Zhu, Jinfang (jeff)

Experimental Structures of Antibody/MHC-I Complexes Reveal Details of Epitopes Overlooked by Computational Prediction

JOURNAL OF IMMUNOLOGY

IF3.4

2024-03-08

OAAI

Boyd, Lisa F.; Jiang, Jiansheng; Ahmad, Javeed; Natarajan, Kannan; Margulies, David H.

SARS-CoV-2 antibodies recognize 23 distinct epitopic sites on the receptor binding domain

COMMUNICATIONS BIOLOGY

IF5.1

2023-09-19

OAAI

Jiang, Jiansheng; Boughter, Christopher T.; Ahmad, Javeed; Natarajan, Kannan; Boyd, Lisa F.; Meier-Schellersheim, Martin; Margulies, David H.

Chaperone function in antigen presentation by MHC class I molecules-tapasin in the PLC and TAPBPR beyond MHC I类分子-tapasin在PLC和TAPBPR之外的抗原呈递中的伴侣功能

FRONTIERS IN IMMUNOLOGY

IF5.9

2023-06-15

OAAI

Margulies, David H.; Jiang, Jiansheng; Ahmad, Javeed; Boyd, Lisa F.; Natarajan, Kannan

Potent monoclonal antibodies neutralize Omicron sublineages and other SARS-CoV-2 variants

CELL REPORTS

IF6.9

2022-11-01

OAAI

Chen, Zhaochun; Zhang, Peng; Matsuoka, Yumiko; Tsybovsky, Yaroslav; West, Kamille; Santos, Celia; Boyd, Lisa F.; Nguyen, Hanh; Pomerenke, Anna; Stephens, Tyler; Olia, Adam S.; Zhang, Baoshan; De Giorgi, Valeria; Holbrook, Michael R.; Gross, Robin; Postnikova, Elena; Garza, Nicole L.; Johnson, Reed F.; Margulies, David H.; Kwong, Peter D.; Alter, Harvey J.; Buchholz, Ursula J.; Lusso, Paolo; Farci, Patrizia

Structural mechanism of tapasin-mediated MHC-I peptide loading in antigen presentation

NATURE COMMUNICATIONS

IF15.7

2022-09-17

OAAI

Jiang, Jiansheng; Taylor, Daniel K.; Kim, Ellen J.; Boyd, Lisa F.; Ahmad, Javeed; Mage, Michael G.; Truong, Hau, V; Woodward, Claire H.; Sgourakis, Nikolaos G.; Cresswell, Peter; Margulies, David H.; Natarajan, Kannan

Developing antisense oligonucleotides for a TECPR2 mutation-induced, ultra-rare neurological disorder using patient-derived cellular models

MOLECULAR THERAPY NUCLEIC ACIDS

IF6.1

2022-09-01

OAAI

Williams, Luis A.; Gerber, David J.; Elder, Amy; Tseng, Wei Chou; Baru, Valeriya; Delaney-Busch, Nathaniel; Ambrosi, Christina; Mahimkar, Gauri; Joshi, Vaibhav; Shah, Himali; Harikrishnan, Karthiayani; Upadhyay, Hansini; Rajendran, Sakthi H.; Dhandapani, Aishwarya; Meier, Joshua; Ryan, Steven J.; Lewarch, Caitlin; Black, Lauren; Douville, Julie; Cinquino, Stefania; Legakis, Helen; Nalbach, Karsten; Behrends, Christian; Sato, Ai; Galluzzi, Lorenzo; Yu, Timothy W.; Brown, Duncan; Agrawal, Sudhir; Margulies, David; Kopin, Alan; Dempsey, Graham T.

Mechanism of Peptide Loading as Revealed by Structure of tapasin/MHC-I Complex

JOURNAL OF IMMUNOLOGY

IF3.4

2022-05-01

PREAI

Jiang, Jiansheng; Taylor, Daniel K.; Kim, Ellen; Boyd, Lisa F.; Cresswell, Peter; Mage, Michael G.; Margulies, David H.; Natarajan, Kannan

Dynamic features of tapasin as revealed by structures of two tapasin/Fab complexes

JOURNAL OF IMMUNOLOGY

IF3.4

2022-05-01

PREAI

Taylor, Daniel Kyle; Jiang, Jiansheng; Boyd, Lisa F.; Cresswell, Peter; Mage, Michael G.; Margulies, David H.; Natarajan, Kannan

Chaperones and Catalysts: How Antigen Presentation Pathways Cope With Biological Necessity

FRONTIERS IN IMMUNOLOGY

IF5.9

2022-04-07

OAAI

Margulies, David H.; Taylor, Daniel K.; Jiang, Jiansheng; Boyd, Lisa F.; Ahmad, Javeed; Mage, Michael G.; Natarajan, Kannan

Structures of synthetic nanobody-SARS-CoV-2 receptor-binding domain complexes reveal distinct sites of interaction

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2021-10-01

OAAI

Ahmad, Javeed; Jiang, Jiansheng; Boyd, Lisa F.; Zeher, Allison; Huang, Rick; Xia, Di; Natarajan, Kannan; Margulies, David H.

Alterations in the HLA-B*57:01 Immunopeptidome by Flucloxacillin and Immunogenicity of Drug-Haptenated Peptides

FRONTIERS IN IMMUNOLOGY

IF5.9

2021-02-09

OAAI

Puig, Montserrat; Ananthula, Suryatheja; Venna, Ramesh; Polumuri, Swamy Kumar; Mattson, Elliot; Walker, Lacey M.; Cardone, Marco; Takahashi, Mayumi; Su, Shan; Boyd, Lisa F.; Natarajan, Kannan; Abdoulaeva, Galina; Wu, Wells W.; Roderiquez, Gregory; Hildebrand, William H.; Beaucage, Serge L.; Li, Zhihua; Margulies, David H.; Norcross, Michael A.

Cutting Edge: Inhibition of the Interaction of NK Inhibitory Receptors with MHC Class I Augments Antiviral and Antitumor Immunity

JOURNAL OF IMMUNOLOGY

IF3.4

2020-08-01

OAAI

Panda, Abir K.; Gangaplara, Arunakumar; Buszko, Maja; Natarajan, Kannan; Boyd, Lisa F.; Sharma, Suveena; Margulies, David H.; Shevach, Ethan M.

Structural and dynamic studies of TAPBPR and Tapasin reveal the mechanism of peptide loading of MHC-I molecules

CURRENT OPINION IN IMMUNOLOGY

IF5.8

2020-06-01

PREAI

Margulies, David H.; Jiang, Jiansheng; Natarajan, Kannan

Mouse Cytomegalovirus m153 Protein Stabilizes Expression of the Inhibitory NKR-P1B Ligand Clr-b

JOURNAL OF VIROLOGY

IF3.8

2019-12-12

OAAI

Aguilar, Oscar A.; Sampaio, Isabella S.; Rahim, Mir Munir A.; Samaniego, Jackeline D.; Tilahun, Mulualem E.; Krishnamoorthy, Mithunah; Popovic, Branka; Babic, Marina; Krmpotic, Astrid; Treanor, Bebhinn; Margulies, David H.; Allan, David S. J.; Makrigiannis, Andrew P.; Jonjic, Stipan; Carlyle, James R.

Cutting antigenic peptides down to size

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2019-12-01

OAAI

Natarajan, Kannan; Margulies, David H.

Structural aspects of chaperone-mediated peptide loading in the MHC-I antigen presentation pathway

CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY

IF6.4

2019-05-14

OAAI

Natarajan, Kannan; Jiang, Jiansheng; Margulies, David H.

The Role of Molecular Flexibility in Antigen Presentation and T Cell Receptor-Mediated Signaling 分子柔性在抗原呈递和T细胞受体介导的信号传导中的作用

FRONTIERS IN IMMUNOLOGY

IF5.9

2018-07-17

OAAI

Natarajan, Kannan; Jiang, Jiansheng; May, Nathan A.; Mage, Michael G.; Boyd, Lisa F.; McShan, Andrew C.; Sgourakis, Nikolaos G.; Bax, Ad; Margulies, David H.

Peptide exchange on MHC-I by TAPBPR is driven by a negative allostery release cycle

NATURE CHEMICAL BIOLOGY

IF13.7

2018-07-09

OAAI

McShan, Andrew C.; Natarajan, Kannan; Kumirov, Vlad K.; Flores-Solis, David; Jiang, Jiansheng; Badstubner, Mareike; Toor, Jugmohit S.; Bagshaw, Clive R.; Kovrigin, Evgenii L.; Margulies, David H.; Sgourakis, Nikolaos G.

A transgenic mouse model for HLA-B*57: 01-linked abacavir drug tolerance and reactivity

JOURNAL OF CLINICAL INVESTIGATION

IF13.6

2018-05-21

OAAI

Cardone, Marco; Garcia, Karla; Tilahun, Mulualem E.; Boyd, Lisa F.; Gebreyohannes, Sintayehu; Yano, Masahide; Roderiquez, Gregory; Akue, Adovi D.; Juengst, Leslie; Mattson, Elliot; Ananthula, Suryatheja; Natarajan, Kannan; Puig, Montserrat; Margulies, David H.; Norcross, Michael A.

研究方向