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Generation of a conditional cellular senescence model using proximal tubule cells and fibroblasts from human kidneys Shao, Xiaohang; Xu, Huaming; Kim, Hyojin; Ljaz, Sadaf; Beier, Fabian; Jankowski, Vera; Lellig, Michaela; Vankann, Lucia; Werner, Jan Niklas; Chen, Lu; Ziegler, Susanne; Kuppe, Christoph; Zenke, Martin; Schneider, Rebekka K.; Hayat, Sikander; Saritas, Turgay; Kramann, Rafael 分享 收藏
Proinflammatory phenotype of iPS cell-derived JAK2 V617F megakaryocytes induces fibrosis in 3D in vitro bone marrow niche Flosdorf, Niclas; Boehnke, Janik; de Toledo, Marcelo A. S.; Lutterbach, Niklas; Lerma, Vanesa Gomez; Grasshoff, Martin; Olschok, Kathrin; Gupta, Siddharth; Tharmapalan, Vithurithra; Schmitz, Susanne; Goetz, Katrin; Schueler, Herdit M.; Maurer, Angela; Sontag, Stephanie; Kuestermann, Caroline; Sere, Kristin; Wagner, Wolfgang; Costa, Ivan G.; Bruemmendorf, Tim H.; Koschmieder, Steffen; Chatain, Nicolas; Castilho, Miguel; Schneider, Rebekka K.; Zenke, Martin 分享 收藏
In situ lipid-loading activates peripheral dendritic cell subsets characterized by cellular ROS accumulation but compromises their capacity to prime näve T cells Christ, Anette; Maas, Sanne L.; Jin, Han; Lu, Chang; Legein, Bart; Wijnands, Erwin; Temmerman, Lieve; Otten, Jeroen; Isaacs, Aaron; Zenke, Martin; Stoll, Monika; Biessen, Erik A. L.; van der Vorst, Emiel P. C. 分享 收藏
Cellular aging is accelerated in the malignant clone of myeloproliferative neoplasms Vieri, Margherita; Tharmapalan, Vithurithra; Kalmer, Milena; Baumeister, Julian; Nikolic, Milos; Schnitker, Matthis; Kirschner, Martin; Flosdorf, Niclas; de Toledo, Marcelo A. S.; Zenke, Martin; Koschmieder, Steffen; Bruemmendorf, Tim H.; Beier, Fabian; Wagner, Wolfgang 分享 收藏
The telomerase inhibitor imetelstat differentially targets JAK2V617F versus CALR mutant myeloproliferative neoplasm cells and inhibits JAK-STAT signaling Olschok, Kathrin; Altenburg, Bianca; de Toledo, Marcelo A. S.; Maurer, Angela; Abels, Anne; Beier, Fabian; Gezer, Deniz; Isfort, Susanne; Paeschke, Katrin; Bruemmendorf, Tim H.; Zenke, Martin; Chatain, Nicolas; Koschmieder, Steffen 分享 收藏
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YAP1 is essential for self-organized differentiation of pluripotent stem cells Zeevaert, Kira; Goetzke, Roman; Mabrouk, Mohamed H. Elsafi; Schmidt, Marco; Maassen, Catharina; Henneke, Ann-Christine; He, Chao; Gillner, Arnold; Zenke, Martin; Wagner, Wolfgang 分享 收藏
Intrathymic dendritic cell-biased precursors promote human T cell lineage specification through IRF8-driven transmembrane TNF 胸腺内树突状细胞偏向性前体通过IRF8-driven跨膜TNF促进人T细胞谱系的规范 Liang, Kai Ling; Roels, Juliette; Lavaert, Marieke; Putteman, Tom; Boehme, Lena; Tilleman, Laurentijn; Velghe, Imke; Pegoretti, Valentina; van de Walle, Inge; Sontag, Stephanie; Vandewalle, Jolien; Vandekerckhove, Bart; Leclercq, Georges; Van Vlierberghe, Pieter; Libert, Claude; Van Nieuwerburgh, Filip; Fischer, Roman; Kontermann, Roland E.; Pfizenmaier, Klaus; Doody, Gina; Zenke, Martin; Taghon, Tom 分享 收藏
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Capitalizing on paradoxical activation of the mitogen-activated protein kinase pathway for treatment of Imatinib-resistant mast cell leukemia Wilhelm, Thomas; Toledo, Marcelo A. S.; Simons, Ilka; Stuth, Christian; Mohta, Vrinda; Muelfarth, Ronja; Nitsche, Marcus; Maschke-Neuss, Karin; Schmitz, Susanne; Kaiser, Anne; Panse, Jens; Christen, Deborah; Arock, Michel; Zenke, Martin; Huber, Michael 分享 收藏
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Towards personalized medicine with iPS cell technology: a case report of advanced systemic mastocytosis with associated eosinophilia Atakhanov, Salim; Christen, Deborah; Rolles, Benjamin; Schueler, Herdit M.; Panse, Jens; Chatain, Nicolas; Koschmieder, Steffen; Brummendorf, Tim H.; Toledo, Marcelo A. S.; Zenke, Martin 分享 收藏
Low Density Lipoprotein Exposure of Plasmacytoid Dendritic Cells Blunts Toll-like Receptor 7/9 Signaling via NUR77 低密度脂蛋白暴露于浆细胞样树突状细胞可通过NUR77使Toll样受体7/9信号通路 Christ, Anette; Goossens, Pieter G.; Wijnands, Erwin; Jin, Han; Legein, Bart; Oth, Tammy; Isaacs, Aaron; Stoll, Monika; Vanderlocht, Joris; Lutgens, Esther; Daemen, Mat J. A. P.; Zenke, Martin; Biessen, Erik A. L. 分享 收藏
PLA/Hydroxyapatite scaffolds exhibit in vitro immunological inertness and promote robust osteogenic differentiation of human mesenchymal stem cells without osteogenic stimuli Bernardo, Marcela P.; da Silva, Bruna C. R.; Hamouda, Ahmed E., I; de Toledo, Marcelo A. S.; Schalla, Carmen; Rutten, Stephan; Goetzke, Roman; Mattoso, Luiz H. C.; Zenke, Martin; Sechi, Antonio 分享 收藏
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