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R

Robbert M. Spaapen

University of Amsterdam
H指数:28
被引数:4,696

个人简介

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教育背景

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工作经历

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荣誉奖项

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Enabling next-generation engineered TCR-T therapies based on high-throughput TCR discovery from diagnostic tumor biopsies

基于从诊断性肿瘤活检样本高通量TCR发现，实现下一代工程化TCR-T疗法

NATURE COMMUNICATIONS
IF15.7
2025-01-140
OA
Kuilman, Thomas; Schrikkema, Deborah S.; Gadiot, Jules; Gomez-Eerland, Raquel; Bies, Laura; Walker, Julia; Spaapen, Robbert M.; Kok, Hanna; Houg, Demi; Viyacheva, Milena; Claassen, Yvonne B.; Saornil, Manuel; Krijgsman, Oscar; Stringer, Bas; Ding, Huiwen; Geleijnse, Anou; Meinema, Anne C.; Weissbrich, Bianca; Lancee, Melissa; Engele, Carmen G.; Sabatino, Marianna; Chen, Pei-Ling; Tsai, Kenneth Y.; Mule, James J.; Sondak, Vernon K.; van den Bulk, Jitske; de Miranda, Noel F.; Jedema, Inge; Haanen, John G.; van Heijst, Jeroen W. J.; Schumacher, Ton N.; Linnemann, Carsten; Bendle, Gavin M.
Elevated expression of complement factor I in lung cancer cells associates with shorter survival-Potentially via non-canonical mechanism

肺癌细胞中补体因子I的表达升高与生存期缩短有关-可能通过非经典机制

TRANSLATIONAL RESEARCH
IF5.9
2024-07-011
PRE
Felberg, Anna; Bienkowski, Michal; Stokowy, Tomasz; Myszczynski, Kamil; Polakiewicz, Zuzanna; Kitowska, Kamila; Sadej, Rafa; Mohlin, Frida; Kuzniewska, Alicja; Kowalska, Daria; Stasilojc, Grzegorz; Jongerius, Ilse; Spaapen, Robbert; Mesa-Guzman, Miguel; Montuenga, Luis M.; Bolm, Anna M.; Pio, Ruben; Okroj, Marcin
Multimodal HLA-I genotype regulation by human cytomegalovirus US10 and resulting surface patterning
ELIFE
IF0
2024-06-201
OA
Gerke, Carolin; Bauersfeld, Liane; Schirmeister, Ivo; Mireisz, Chiara Noemi-Marie; Oberhardt, Valerie; Mery, Lea; Wu, Di; Juerges, Christopher Sebastian; Spaapen, Robbert M.; Mussolino, Claudio; Le-Trilling, Vu Thuy Khanh; Trilling, Mirko; Doelken, Lars; Paster, Wolfgang; Erhard, Florian; Hofmann, Maike; Schlosser, Andreas; Hengel, Hartmut; Momburg, Frank; Halenius, Anne
Gain-of-Function Mutations R249C and S250C in Complement C2 Protein Increase C3 Deposition in the Presence of C-Reactive Protein

补体C2蛋白中的功能获得性突变R249C和S250C在C反应蛋白存在下增加C3沉积

FRONTIERS IN IMMUNOLOGY
IF5.9
2021-11-2510
OAAI
Urban, Aleksandra; Kowalska, Daria; Stasilojc, Grzegorz; Kuzniewska, Alicja; Skrobinska, Anna; Arjona, Emilia; Alonso, Eugenia Castellote; Fenollosa Segarra, Maria Angeles; Jongerius, Ilse; Spaapen, Robbert; Satchell, Simon; Thiel, Marcel; Oldziej, Stanislaw; Rodriguez de Cordoba, Santiago; Okroj, Marcin
The SPPL3-defined glycosphingolipid repertoire orchestrates HLA class I-mediated immune responses (vol 54, 132.e1, 2021)

SPPL3-defined鞘糖脂库协调HLA I类介导的免疫反应 (第54卷，132.e1，2021)

IMMUNITY
IF26.3
2021-02-0111
OAAI
Jongsma, Marlieke L. M.; de Waard, Antonius A.; Raaben, Matthijs; Zhang, Tao; Cabukusta, Birol; Platzer, Rene; Blomen, Vincent A.; Xagara, Anastasia; Verkerk, Tamara; Bliss, Sophie; Kong, Xiangrui; Gerke, Carolin; Janssen, Lennert; Stickel, Elmer; Holst, Stephanie; Plomp, Rosina; Mulder, Arend; Ferrone, Soldano; Claas, Frans H. J.; Heemskerk, Mirjam H. M.; Griffioen, Marieke; Halenius, Anne; Overkleeft, Hermen; Huppa, Johannes B.; Wuhrer, Manfred; Brummelkamp, Thijn R.; Neefjes, Jacques; Spaapen, Robbert M.
The SPPL3-Defined Glycosphingolipid Repertoire Orchestrates HLA Class I-Mediated Immune Responses

SPPL3-Defined鞘糖脂库协调HLA I类介导的免疫反应

IMMUNITY
IF26.3
2021-01-0162
OAAI
Jongsma, Marlieke L. M.; de Waard, Antonius A.; Raaben, Matthijs; Zhang, Tao; Cabukusta, Birol; Platzer, Rene; Blomen, Vincent A.; Xagara, Anastasia; Verkerk, Tamara; Bliss, Sophie; Kong, Xiangrui; Gerke, Carolin; Janssen, Lennert; Stickel, Elmer; Holst, Stephanie; Plomp, Rosina; Mulder, Arend; Ferrone, Soldano; Claas, Frans H. J.; Heemskerk, Mirjam H. M.; Griffioen, Marieke; Halenius, Anne; Overkleeft, Hermen; Huppa, Johannes B.; Wuhrer, Manfred; Brummelkamp, Thijn R.; Neefjes, Jacques; Spaapen, Robbert M.
Polyfunctional tumor-reactive T cells are effectively expanded from non-small cell lung cancers, and correlate with an immune-engaged T cell profile
ONCOIMMUNOLOGY
IF6.3
2019-08-1543
OAAI
De Groot, Rosa; Van Loenen, Marleen M.; Guislain, Aurelie; Nicolet, Benoit P.; Freen-Van Heeren, Julian J.; Verhagen, Onno J. H. M.; Van Den Heuvel, Michel M.; De Jong, Jeroen; Burger, Patrick; Van Der Schoot, C. Ellen; Spaapen, Robbert M.; Amsen, Derk; Haanen, John B. A. G.; Monkhorst, Kim; Hartemink, Koen J.; Wolkers, Monika C.

研究方向

暂未获取到该数据
M
Marlieke L.M. Jongsma
H 指数:20论文数:55被引数:3,684
J
Jacques Neefjes
H 指数:104论文数:547被引数:3.9万
M
Marieke Griffioen
H 指数:34论文数:215被引数:3,986
T
Tuna Mutis
H 指数:61论文数:344被引数:1.3万
T
Tamara Verkerk
H 指数:6论文数:18被引数:203
Y
Yan Zheng
H 指数:27论文数:71被引数:4,448
H
Henk M. Lokhorst
H 指数:63论文数:346被引数:1.8万
K
Kelly van den Oudenalder
H 指数:6论文数:15被引数:194
T
Thomas F. Gajewski
H 指数:95论文数:639被引数:5.5万
M
Manfred Wuhrer
H 指数:98论文数:649被引数:3.1万