未登录 Batf3+DCs and the 4-1BB/4-1BBL axis are required at the effector phase in the tumor microenvironment for PD-1/PD-L1 blockade efficacy Batf3 DCs和4-1BB/4-1BBL轴在肿瘤微环境的效应阶段是PD-1/PD-L1阻断功效所必需的 Ziblat, Andrea; Horton, Brendan L.; Higgs, Emily F.; Hatogai, Ken; Martinez, Anna; Shapiro, Jason W.; Kim, Danny E. C.; Zha, Yuanyuan; Sweis, Randy F.; Gajewski, Thomas F. 分享 收藏
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Decr2 regulates tumor cell ferroptosis and immunotherapy efficacy Li, Shuyin; Shapiro, Jason; Shah, Hardik; Higgs, Emily F.; Xie, Lishi; Zha, Yuanyuan; Trujillo, Jonathan; Cabanov, Alexandra; Jones, Tyler A.; Flood, Blake; Hatogai, Ken; Kline, Justin; Gajewski, Thomas F. 分享 收藏
Germline immunomodulatory expression quantitative trait loci (ieQTLs) associated with immune-related toxicity from checkpoint inhibition 种系免疫调节表达与检查点抑制引起的免疫相关毒性相关的数量性状基因座 (ieqtl) Ferguson, Robert; Chat, Vylyny; Morales, Leah; Smpson, Danny; Monson, Kelsey R.; Cohen, Elisheva; Zusin, Sarah; Madonna, Gabriele; Capone, Mariaelena; Simeone, Ester; Pavlick, Anna; Luke, Jason J.; Gajewski, Thomas F.; Osman, Iman; Ascierto, Paolo; Weber, Jeffrey; Kirchhoff, Tomas 分享 收藏
Perspectives in Melanoma: meeting report from the Melanoma Bridge (December 1st-3rd, 2022-Naples, Italy) 黑色素瘤的观点: 黑色素瘤桥会议报告 (2022年12月1至3日-意大利那不勒斯) Ascierto, Paolo A.; Agarwala, Sanjiv S.; Warner, Allison Betof; Ernstoff, Marc S.; Fox, Bernard A.; Gajewski, Thomas F.; Galon, Jerome; Garbe, Claus; Gastman, Brian R.; Gershenwald, Jeffrey E.; Kalinski, Pawel; Krogsgaard, Michelle; Leidner, Rom S.; Lo, Roger S.; Menzies, Alexander M.; Michielin, Olivier; Poulikakos, Poulikos I.; Weber, Jeffrey S.; Caraco, Corrado; Osman, Iman; Puzanov, Igor; Thurin, Magdalena 分享 收藏
Phase 1 dose-escalation study of SEA-CD40: a non-fucosylated CD40 agonist, in advanced solid tumors and lymphomas SEA-CD40的1期剂量递增研究: 非岩藻糖基化CD40激动剂,用于晚期实体瘤和淋巴瘤 Coveler, Andrew L.; Smith, David C.; Phillips, Tycel; Curti, Brendan D.; Goel, Sanjay; Mehta, Amitkumar N.; Kuzel, Timothy M.; Markovic, Svetomir N.; Rixe, Olivier; Bajor, David L.; Gajewski, Thomas F.; Gutierrez, Martin; Lee, Hun Ju; Gopal, Ajay K.; Caimi, Paolo; Heath, Elisabeth, I; Thompson, John A.; Ansari, Sahar; Jacquemont, Celine; Topletz-Erickson, Ariel; Zhou, Peigen; Schmitt, Michael W.; Grilley-Olson, Juneko E. 分享 收藏
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Lymphatic coagulation and neutrophil extracellular traps in lung-draining lymph nodes of COVID-19 decedents 新型冠状病毒肺炎死者肺引流淋巴结中的淋巴凝结和中性粒细胞细胞外诱捕器 MacDonald, Margo E.; Weathered, Rachel K.; Stewart, Emma C.; Magold, Alexandra I.; Mukherjee, Anish; Gurbuxani, Sandeep; Smith, Heather; McMullen, Phillip; Mueller, Jeffrey; Husain, Aliya N.; Salles, Calixto M.; Briquez, Priscilla S.; Rouhani, Sherin J.; Yu, Jovian; Trujillo, Jonathan; Pyzer, Athalia R.; Gajewski, Thomas F.; Sperling, Anne I.; Kilarski, Witold W.; Swartz, Melody A. 分享 收藏
Highly aneuploid non-small cell lung cancer shows enhanced responsiveness to concurrent radiation and immune checkpoint blockade 高度非整倍体非小细胞肺癌显示出对同时放射和免疫检查点阻断的反应性增强 Spurr, Liam F.; Martinez, Carlos A.; Kang, Wenjun; Chen, Mengjie; Zha, Yuanyuan; Hseu, Robyn; Gutiontov, Stanley, I; Turchan, William T.; Lynch, Connor M.; Pointer, Kelli B.; Chang, Paul; Murgu, Septimiu; Husain, Aliya N.; Cody, Brittany; Vokes, Everett E.; Bestvina, Christine M.; Patel, Jyoti D.; Diehn, Maximilian; Gajewski, Thomas F.; Weichselbaum, Ralph R.; Chmura, Steven J.; Pitroda, Sean P. 分享 收藏
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Severe COVID-19 induces autoantibodies against angiotensin II that correlate with blood pressure dysregulation and disease severity 严重新型冠状病毒肺炎诱导针对血管紧张素II的自身抗体,其与血压失调和疾病严重程度相关 Briquez, Priscilla S.; Rouhani, Sherin J.; Yu, Jovian; Pyzer, Athalia R.; Trujillo, Jonathan; Dugan, Haley L.; Stamper, Christopher T.; Changrob, Siriruk; Sperling, Anne, I; Wilson, Patrick C.; Gajewski, Thomas F.; Hubbell, Jeffrey A.; Swartz, Melody A. 分享 收藏
Perspectives in Melanoma: meeting report from the Melanoma Bridge (December 2nd-4th, 2021, Italy) 黑色素瘤的观点: 黑色素瘤桥会议报告 (意大利2021年12月2至4日) Ascierto, Paolo A.; Agarwala, Sanjiv S.; Blank, Christian; Caraco, Corrado; Carvajal, Richard D.; Ernstoff, Marc S.; Ferrone, Soldano; Fox, Bernard A.; Gajewski, Thomas F.; Garbe, Claus; Grob, Jean-Jacques; Hamid, Omid; Krogsgaard, Michelle; Lo, Roger S.; Lund, Amanda W.; Madonna, Gabriele; Michielin, Olivier; Neyns, Bart; Osman, Iman; Peters, Solange; Poulikakos, Poulikos, I; Quezada, Sergio A.; Reinfeld, Bradley; Zitvogel, Laurence; Puzanov, Igor; Thurin, Magdalena 分享 收藏
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MASTERKEY-265: A phase III, randomized, placebo (Pbo)-controlled study of talimogene laherparepvec (T) plus pembrolizumab (P) for unresectable stage IIIB-IVM1c melanoma (MEL) MASTERKEY-265: talimogene laherparepvec (T) 联合pembrolizumab (P) 治疗不可切除期IIIB-IVM1c黑色素瘤 (MEL) 的III期随机安慰剂 (Pbo) 对照研究 Ribas, A.; Chesney, J.; Long, G. V.; Kirkwood, J. M.; Dummer, R.; Puzanov, I.; Hoeller, C.; Gajewski, T. F.; Gutzmer, R.; Rutkowski, P.; Demidov, L.; Arenberger, P.; Shin, S. J.; Ferrucci, P. F.; Diede, S. J.; Anderson, J. R.; Treichel, S.; Chan, E.; Hodi, F. S.; Gogas, H. J. 分享 收藏
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Immunogenomic determinants of tumor microenvironment correlate with superior survival in high-risk neuroblastoma 肿瘤微环境的免疫基因组决定因素与高危神经母细胞瘤的高生存率相关 Bao, Riyue; Spranger, Stefani; Hernandez, Kyle; Zha, Yuanyuan; Pytel, Peter; Luke, Jason J.; Gajewski, Thomas F.; Volchenboum, Samuel L.; Cohn, Susan L.; Desai, Ami, V 分享 收藏