未登录 Mouse-adapted SARS-CoV-2 Omicron BA.5 infection induces post-acute lung fibrosis in BALB/c mice 小鼠适应性SARS-CoV-2 Omicron BA.5感染诱导BALB/c小鼠发生急性后肺纤维化 Powers, John M.; Leist, Sarah R.; Suryadevara, Naveenchandra; Zost, Seth J.; Binshtein, Elad; Abdelgadir, Anfal; Mallory, Michael L.; Edwards, Caitlin E.; Gully, Kendra L.; Hubbard, Miranda L.; Zweigart, Mark R.; Bailey, Alexis B.; Sheahan, Timothy P.; Crowe, James E.; Montgomery, Stephanie A.; Harkema, Jack R.; Baric, Ralph S. 分享 收藏
The oral nucleoside prodrug GS-5245 is efficacious against SARS-CoV-2 and other endemic, epidemic, and enzootic coronaviruses Martinez, David R.; Moreira, Fernando R.; Catanzaro, Nicholas J.; Diefenbacher, Meghan V.; Zweigart, Mark R.; Gully, Kendra L.; De la Cruz, Gabriela; Brown, Ariane J.; Adams, Lily E.; Yount, Boyd; Baric, Thomas J.; Mallory, Michael L.; Conrad, Helen; May, Samantha R.; Dong, Stephanie; Scobey, D. Trevor; Nguyen, Cameron; Montgomery, Stephanie A.; Perry, Jason K.; Babusis, Darius; Barrett, Kimberly T.; Nguyen, Anh-Hoa; Nguyen, Anh-Quan; Kalla, Rao; Bannister, Roy; Feng, Joy Y.; Cihlar, Tomas; Baric, Ralph S.; Mackman, Richard L.; Bilello, John P.; Schaefer, Alexandra; Sheahan, Timothy P. 分享 收藏
Efficacy of host cell serine protease inhibitor MM3122 against SARS-CoV-2 for treatment and prevention of COVID-19 Boon, Adrianus C. M.; Bricker, Traci L.; Fritch, Ethan J.; Leist, Sarah R.; Gully, Kendra; Baric, Ralph S.; Graham, Rachel L.; Troan, Brigid V.; Mahoney, Matthew; Janetka, James W. 分享 收藏
Mapping of susceptibility loci for Ebola virus pathogenesis in mice Schafer, Alexandra; Marzi, Andrea; Furuyama, Wakako; Catanzaro, Nicholas J.; Nguyen, Cameron; Haddock, Elaine; Feldmann, Friederike; Meade-White, Kimberly; Thomas, Tina; Hubbard, Miranda L.; Gully, Kendra L.; Leist, Sarah R.; Hock, Pablo; Bell, Timothy A.; De la Cruz, Gabriela E.; Midkiff, Bentley R.; Martinez, David R.; Shaw, Ginger D.; Miller, Darla R.; Vernon, Michael J.; Graham, Rachel L.; Cowley, Dale O.; Montgomery, Stephanie A.; Schughart, Klaus; de Villena, Fernando Pardo Manuel; Wilkerson, Gregory K.; Ferris, Martin T.; Feldmann, Heinz; Baric, Ralph S. 分享 收藏
BCG vaccination stimulates integrated organ immunity by feedback of the adaptive immune response to imprint prolonged innate antiviral resistance BCG疫苗接种通过适应性免疫反应的反馈来刺激整合器官免疫，以印记长期的先天抗病毒药物抗性 Lee, Audrey; Floyd, Katharine; Wu, Shengyang; Fang, Zhuoqing; Tan, Tze Kai; Froggatt, Heather M.; Powers, John M.; Leist, Sarah R.; Gully, Kendra L.; Hubbard, Miranda L.; Li, Chunfeng; Hui, Harold; Scoville, David; Ruggiero, Alistaire D.; Liang, Yan; Pavenko, Anna; Lujan, Victor; Baric, Ralph S.; Nolan, Garry P.; Arunachalam, Prabhu S.; Suthar, Mehul S.; Pulendran, Bali 分享 收藏
Vaccine-mediated protection against Merbecovirus and Sarbecovirus challenge in mice Martinez, David R.; Schafer, Alexandra; Gavitt, Tyler D.; Mallory, Michael L.; Lee, Esther; Catanzaro, Nicholas J.; Chen, Haiyan; Gully, Kendra; Scobey, Trevor; Korategere, Pooja; Brown, Alecia; Smith, Lena; Parks, Robert; Barr, Maggie; Newman, Amanda; Bowman, Cindy; Powers, John M.; Soderblom, Erik J.; Mansouri, Katayoun; Edwards, Robert J.; Baric, Ralph S.; Haynes, Barton F.; Saunders, Kevin O. 分享 收藏
1-O-Octadecyl-2-O-benzyl-sn-glyceryl-3-phospho-GS-441524 (V2043). Evaluation of Oral V2043 in a Mouse Model of SARS-CoV-2 Infection and Synthesis and Antiviral Evaluation of Additional Phospholipid Esters with Enhanced Anti-SARS-CoV-2 Activity Carlin, Aaron F.; Beadle, James R.; Clark, Alex E.; Gully, Kendra L.; Moreira, Fernando R.; Baric, Ralph S.; Graham, Rachel L.; Valiaeva, Nadejda; Leibel, Sandra L.; Bray, William; McMillan, Rachel E.; Freshman, Jonathan E.; Garretson, Aaron F.; McVicar, Rachael N.; Rana, Tariq; Zhang, Xing-Quan; Murphy, Joyce A.; Schooley, Robert T.; Hostetler, Karl Y. 分享 收藏
Fc-mediated pan-sarbecovirus protection after alphavirus vector vaccination Adams, Lily E.; Leist, Sarah R.; Dinnon III, Kenneth H.; West, Ande; Gully, Kendra L.; Anderson, Elizabeth J.; Loome, Jennifer F.; Madden, Emily A.; Powers, John M.; Schafer, Alexandra; Sarkar, Sanjay; Castillo, Izabella N.; Maron, Jenny S.; McNamara, Ryan P.; Bertera, Harry L.; Zweigert, Mark R.; Higgins, Jaclyn S.; Hampton, Brea K.; Premkumar, Lakshmanane; Alter, Galit; Montgomery, Stephanie A.; Baxter, Victoria K.; Heise, Mark T.; Baric, Ralph S. 分享 收藏
Human ACE2 expression, a major tropism determinant for SARS-CoV-2, is regulated by upstream and intragenic elements Snouwaert, John N.; Jania, Leigh A.; Nguyen, Trang; Martinez, David R.; Schafer, Alexandra; Catanzaro, Nicholas J.; Gully, Kendra L.; Baric, Ralph S.; Heise, Mark; Ferris, Martin T.; Anderson, Elizabeth; Pressey, Katia; Dillard, Jacob A.; Taft-Benz, Sharon; Baxter, Victoria K.; Ting, Jenny P-Y; Koller, Beverly H. 分享 收藏
SARS-CoV-2 infection produces chronic pulmonary epithelial and immune cell dysfunction with fibrosis in mice Dinnon, Kenneth H., III; Leist, Sarah R.; Okuda, Kenichi; Dang, Hong; Fritch, Ethan J.; Gully, Kendra L.; De la Cruz, Gabriela; Evangelista, Mia D.; Asakura, Takanori; Gilmore, Rodney C.; Hawkins, Padraig; Nakano, Satoko; West, Ande; Schafer, Alexandra; Gralinski, Lisa E.; Everman, Jamie L.; Sajuthi, Satria P.; Zweigart, Mark R.; Dong, Stephanie; McBride, Jennifer; Cooley, Michelle R.; Hines, Jesse B.; Love, Miriya K.; Groshong, Steve D.; VanSchoiack, Alison; Phelan, Stefan J.; Liang, Yan; Hether, Tyler; Leon, Michael; Zumwalt, Ross E.; Barton, Lisa M.; Duval, Eric J.; Mukhopadhyay, Sanjay; Stroberg, Edana; Borczuk, Alain; Thorne, Leigh B.; Sakthivel, Muthu K.; Lee, Yueh Z.; Hagood, James S.; Mock, Jason R.; Seibold, Max A.; O'Neal, Wanda K.; Montgomery, Stephanie A.; Boucher, Richard C.; Baric, Ralph S. 分享 收藏
A Multitrait Locus Regulates Sarbecovirus Pathogenesis Schafer, Alexandra; Leist, Sarah R.; Gralinski, Lisa E.; Martinez, David R.; Winkler, Emma S.; Okuda, Kenichi; Hawkins, Padraig E.; Gully, Kendra L.; Graham, Rachel L.; Scobey, D. Trevor; Bell, Timothy A.; Hock, Pablo; Shaw, Ginger D.; Loome, Jennifer F.; Madden, Emily A.; Anderson, Elizabeth; Baxter, Victoria K.; Taft-Benz, Sharon A.; Zweigart, Mark R.; May, Samantha R.; Dong, Stephanie; Clark, Matthew; Miller, Darla R.; Lynch, Rachel M.; Heise, Mark T.; Tisch, Roland; Boucher, Richard C.; de Villena, Fernando Pardo Manuel; Montgomery, Stephanie A.; Diamond, Michael S.; Ferris, Martin T.; Baric, Ralph S. 分享 收藏
Therapeutic treatment with an oral prodrug of the remdesivir parental nucleoside is protective against SARS-CoV-2 pathogenesis in mice Schafer, Alexandra; Martinez, David R.; Won, John J.; Meganck, Rita M.; Moreira, Fernando R.; Brown, Ariane J.; Gully, Kendra L.; Zweigart, Mark R.; Conrad, William S.; May, Samantha R.; Dong, Stephanie; Kalla, Rao; Chun, Kwon; Du Pont, Venice; Babusis, Darius; Tang, Jennifer; Murakami, Eisuke; Subramanian, Raju; Barrett, Kimberly T.; Bleier, Blake J.; Bannister, Roy; Feng, Joy Y.; Bilello, John P.; Cihlar, Tomas; Mackman, Richard L.; Montgomery, Stephanie A.; Baric, Ralph S.; Sheahan, Timothy P. 分享 收藏
Prevention and therapy of SARS-CoV-2 and the B.1.351 variant in mice Martinez, David R.; Schafer, Alexandra; Leist, Sarah R.; Li, Dapeng; Gully, Kendra; Yount, Boyd; Feng, Joy Y.; Bunyan, Elaine; Porter, Danielle P.; Cihlar, Tomas; Montgomery, Stephanie A.; Haynes, Barton F.; Baric, Ralph S.; Nussenzweig, Michel C.; Sheahan, Timothy P. 分享 收藏
Swine acute diarrhea syndrome coronavirus replication in primary human cells reveals potential susceptibility to infection Edwards, Caitlin E.; Yount, Boyd L.; Graham, Rachel L.; Leist, Sarah R.; Hou, Yixuan J.; Dinnon, Kenneth H., III; Sims, Amy C.; Swanstrom, Jesica; Gully, Kendra; Scobey, Trevor D.; Cooley, Michelle R.; Currie, Caroline G.; Randell, Scott H.; Baric, Ralph S. 分享 收藏
Remdesivir Inhibits SARS-CoV-2 in Human Lung Cells and Chimeric SARS-CoV Expressing the SARS-CoV-2 RNA Polymerase in Mice Remdesivir抑制人肺细胞和小鼠中表达SARS-CoV-2 RNA聚合酶的嵌合传染性非典型肺炎-CoV的SARS-CoV-2 Pruijssers, Andrea J.; George, Amelia S.; Schafer, Alexandra; Leist, Sarah R.; Gralinksi, Lisa E.; Dinnon, Kenneth H., III; Yount, Boyd L.; Agostini, Maria L.; Stevens, Laura J.; Chappell, James D.; Lu, Xiaotao; Hughes, Tia M.; Gully, Kendra; Martinez, David R.; Brown, Ariane J.; Graham, Rachel L.; Perry, Jason K.; Du Pont, Venice; Pitts, Jared; Ma, Bin; Babusis, Darius; Murakami, Eisuke; Feng, Joy Y.; Bilello, John P.; Porter, Danielle P.; Cihlar, Tomas; Baric, Ralph S.; Denison, Mark R.; Sheahan, Timothy P. 分享 收藏
Structure of mouse coronavirus spike protein complexed with receptor reveals mechanism for viral entry Shang, Jian; Wan, Yushun; Liu, Chang; Yount, Boyd; Gully, Kendra; Yang, Yang; Auerbach, Ashley; Peng, Guiqing; Baric, Ralph; Li, Fang 分享 收藏
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