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G

G.R. Andersen

aarhus university

52H指数
259论文数
8.0K被引数
收录论文 102
发表时间
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The plasma protease inhibitor ITIH4 forms oligomeric complexes and senses broader proteolytic activity血浆蛋白酶抑制剂ITIH4形成寡聚复合物并感知更广泛的蛋白水解活性
errNature Communications
IF15.7
err2026-09-28
err0
errOAAI
errMartin Høgholm Jørgensen; Annette Gudmann Hansen; Ana Casañal; Steffen Thiel; Gregers Rom Andersen
err分享
err收藏
Three cryo-EM structures of complement C3d-bound αMβ2 reveal an unexpected layer of dynamics for αI-containing integrin receptors三种补体C3d结合的αMβ2的冷冻电镜结构揭示了αI包含整合素受体的一个意想不到的动态层面
errScience Advances
IF12.5
err2026-05-08
err0
errOAAI
errJosefine Lorentzen; Marlene Uglebjerg Fruergaard; Szilvia Lukácsi; Martin Høgholm Jørgensen; Timo Lambertus Gerardus van Veghel; Rasmus Kjeldsen Jensen; Krzysztof Jakub Pietrzak-Lichwa; Zsuzsa Bajtay; Václav Hořejší; Rasmus Kock Flygaard; Daan Vorselen; Simon Arnold Mortensen; Gregers Rom Andersen
err分享
err收藏
Structure–function analysis of empasiprubart, a calcium- and pH-dependent clinical phase complement C2 blocking antibody钙离子和pH依赖性临床阶段补体C2阻断抗体empasiprubart的结构-功能分析
errmAbs
IF7.3
err2026-05-04
err0
errOAAI
errLaura Bracke; Heidi Gytz Olesen; Erwin Pannecoucke; Tim Delahaye; Emma K. Persson; Christophe Blanchetot; Hans de Haard; C. Erik Hack; Gregers Rom Andersen; Inge Van de Walle
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Nanobody-based IgG simultaneously inhibit the allergenic and enzymatic activity of the dominant honeybee venom allergen基于纳米抗体的IgG同时抑制主要蜜蜂毒液过敏原的过敏原性和酶活性
errNature Communications
IF15.7
err2026-02-17
err0
errOAAI
errAagaard, Josephine Baunvig; Gandini, Rosaria; Ballegaard, Anne-Sofie Ravn; Jensen, Bjarke Krogstrup; Dorn, Britta; Larsen, Amanda Verner Borg; Lenstrup, Anders; Sonderholm, Mathias; Miehe, Michaela; Pfutzner, Wolfgang; Jakob, Thilo; Andersen, Gregers Rom; Mobs, Christian; Spillner, Edzard
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Antagonist nanobodies prevent protease inhibition by CD109
errJournal of Biological Chemistry
IF3.9
err2026-01-23
err0
errOAAI
errKathrine Tejlgård Jensen; Ana Viana Almeida; Sanne Rönning; Maximillian Karlander; Nadia Sukusu Nielsen; Ida B. Thøgersen; Magdalena Malm; Gregers Rom Andersen; Jan J. Enghild; Johan Rockberg; Seandean Lykke Harwood
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Cryo-EM Structure of FcεRI Bound IgE Reveals Multiple Defined Conformations of the Fab-Fc HingeFcεRI结合IgE的冷冻电镜结构揭示Fab-Fc铰链区的多种特定构象
errAllergy
IF12
err2025-11-06
err0
PREAI
errRasmus K. Jensen; Michaela Miehe; Rosaria Gandini; Martin H. Jørgensen; Edzard Spillner; Gregers R. Andersen
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err收藏
Nanobody-based gene therapy targeting complement component C3 reduces choroidal neovascularization in mice基于纳米抗体的基因疗法靶向补体成分C3可减少小鼠脉络膜新生血管形成
errMolecular Therapy Methods & Clinical Development
IF4.7
err2025-10-25
err0
errOAAI
errEmilie Grarup Jensen; Thomas Stax Jakobsen; Gloriane Schnabolk; Kyrie Wilson; Mathias Rask-Pedersen; Nanna Jensen; Gregers Rom Andersen; Steffen Thiel; Lars Aagaard; Bärbel Rohrer; Anne Louise Askou; Thomas J. Corydon
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SGLT2 inhibition protects kidney function by SAM-dependent epigenetic repression of inflammatory genes under metabolic stressSGLT2抑制剂通过SAM依赖的表观遗传抑制代谢应激下的炎症基因来保护肾功能。
errJOURNAL OF CLINICAL INVESTIGATION
IF13.6
err2025-10-01
err0
PREAI
errMaekawa, Hiroshi; Zhou, Yalu; Aoi, Yuki; Fain, Margaret E.; Kaminski, Dorian S.; Kong, Hyewon; Sebo, Zachary L.; Chakrabarty, Ram P.; Howard, Benjamin C.; Andersen, Grant; Marcheva, Biliana; Gao, Peng; Kapitsinou, Pinelopi; Bass, Joseph; Shilatifard, Ali; Chandel, Navdeep S.; Quaggin, Susan E.
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Randomized phase I trial outcomes show safe and sustainable inhibition of classical and lectin complement pathways by empasiprubart随机I期临床试验结果表明，empasiprubart能够安全且可持续地抑制经典和凝集素补体通路。
errNature Communications
IF15.7
err2025-08-16
err0
errOAAI
errInge Van de Walle; Laura Bracke; Heidi Gytz Olesen; Tonke van Bragt; Stéphanie Cadour; Phillip De Decker; Giorgia Ciurlia; Erwin Pannecoucke; Emma K. Persson; Olivier Van de Steen; Xinghong Leng; Gregers Rom Andersen; Domenica Gandini; C. Erik Hack
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Characterization of the bispecific VHH antibody tarperprumig (ALXN1820) specific for properdin and designed for low-volume administration
errMABS
IF7.3
err2024-10-13
err0
errOAAI
errTamburini, Paul; Pedersen, Dennis Vestergaard; Devore, Denise; Cone, Josh; Patel, Rekha; Hunter, Todd; Sun, Fang; Andersen, Gregers Rom; Hunter, Jeffrey
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Humanization of a mouse anti-human complement C6 monoclonal antibody as a potential therapeutic for certain complement-mediated diseases小鼠抗人补体C6单克隆抗体的人源化作为某些补体介导的疾病的潜在治疗剂
errMOLECULAR IMMUNOLOGY
IF3
err2024-06-01
err0
errOAAI
errZhang, Lingjun; Armour, Kathryn; Chen, Jin Y.; Mylona, Agathi; Yang, Maojing; Andersen, Gregers R.; Maciejewki, Jaroslaw P.; Bakrania, Preeti; Lin, Feng
err分享
err收藏
Trypanosoma brucei Invariant Surface Glycoprotein 75 Is an Immunoglobulin Fc Receptor Inhibiting Complement Activation and Antibody-Mediated Cellular Phagocytosis
errJOURNAL OF IMMUNOLOGY
IF3.4
err2024-02-23
err0
PREAI
errMikkelsen, Jakob Hauge; Stodkilde, Kristian; Jensen, Maria Pauladottir; Hansen, Annette Gudmann; Wu, Qi; Lorentzen, Josefine; Graversen, Jonas Heilskov; Andersen, Gregers Rom; Fenton, Robert Andrew; Etzerodt, Anders; Thiel, Steffen; Andersen, Christian Brix Folsted
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Amyloid-β aggregates activate peripheral monocytes in mild cognitive impairment淀粉样蛋白-β 聚集体在轻度认知障碍中激活外周单核细胞
errNATURE COMMUNICATIONS
IF15.7
err2024-02-09
err4
errOAAI
errJuul-Madsen, Kristian; Parbo, Peter; Ismail, Rola; Ovesen, Peter L.; Schmidt, Vanessa; Madsen, Lasse S.; Thyrsted, Jacob; Gierl, Sarah; Breum, Mihaela; Larsen, Agnete; Andersen, Morten N.; Romero-Ramos, Marina; Holm, Christian K.; Andersen, Gregers R.; Zhao, Huaying; Schuck, Peter; Nygaard, Jens V.; Sutherland, Duncan S.; Eskildsen, Simon F.; Willnow, Thomas E.; Brooks, David J.; Vorup-Jensen, Thomas
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Characterization of the bispecific VHH antibody gefurulimab (ALXN1720) targeting complement component 5, and designed for low volume subcutaneous administration
errMOLECULAR IMMUNOLOGY
IF3
err2024-01-01
err4
errOAAI
errJindal, Siddharth; Pedersen, Dennis Vestergaard; Gera, Nimish; Chandler, Julian; Patel, Rekha; Neill, Alyssa; Cone, Josh; Zhang, Yuchun; Yuan, Chao-Xing; Millman, Ellen E.; Carlin, Dan; Puffer, Bridget; Sheridan, Douglas; Andersen, Gregers Rom; Tamburini, Paul
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Chemical Zymogens and Transmembrane Activation of Transcription in Synthetic Cells化学酶原和合成细胞中转录的跨膜激活
errADVANCED MATERIALS
IF26.8
err2023-12-06
err5
errOAAI
errAndersen, Dante Guldbrandsen; Pedersen, Andreas Botker; Jorgensen, Martin Hogholm; Montasell, Mireia Casanovas; Sogaard, Ane Bretschneider; Chen, Gal; Schroeder, Avi; Andersen, Gregers Rom; Zelikin, Alexander N.
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Computer-aided discovery of a novel thermophilic laccase for low-density polyethylene degradation
errJOURNAL OF HAZARDOUS MATERIALS
IF11.3
err2023-09-01
err9
errOAAI
errZhang, Yan; Plesner, Thea Jess; Ouyang, Yi; Zheng, Yu-Cong; Bouhier, Etienne; Berentzen, Emilie Ingemann; Zhang, Mingliang; Zhou, Pengfei; Zimmermann, Wolfgang; Andersen, Gregers Rom; Eser, Bekir Engin; Guo, Zheng
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Bispecific Complement Engagers for Targeted Complement Activation
errJOURNAL OF IMMUNOLOGY
IF3.4
err2023-08-01
err6
PREAI
errPedersen, Dennis, V; Gytz, Heidi; Winkler, Mikael B. L.; Zarantonello, Alessandra; Baumann, Niklas; Hansen, Annette G.; Thiel, Steffen; Andersen, Gregers R.; Valerius, Thomas; Laursen, Nick S.
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Trypanosoma brucei Invariant Surface gp65 Inhibits the Alternative Pathway of Complement by Accelerating C3b Degradation
errJOURNAL OF IMMUNOLOGY
IF3.4
err2023-07-19
err4
PREAI
errLorentzen, Josefine; Olesen, Heidi G.; Hansen, Annette G.; Thiel, Steffen; Birkelund, Svend; Andersen, Christian B. F.; Andersen, Gregers R.
err分享
err收藏
A potent complement factor C3-specific nanobody inhibiting multiple functions in the alternative pathway of human and murine complement (vol 293, pg 6269, 2018)
errJOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
err2023-02-01
err1
errOAAI
errJensen, Rasmus K.; Pihl, Rasmus; Gadeberg, Trine A. F.; Jensen, Jan K.; Andersen, Kasper R.; Thiel, Steffen; Laursen, Nick S.; Andersen, Gregers R.
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Structural studies offer a framework for understanding the role of properdin in the alternative pathway and beyond
errIMMUNOLOGICAL REVIEWS
IF8.3
err2022-09-13
err8
errOAAI
errPedersen, Dennis Vestergaard; Lorentzen, Josefine; Andersen, Gregers Rom
err分享
err收藏

研究方向

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合作学者
合作期刊
T
Timothy A. Springer
H 指数: 165 · 论文数: 734
J
John D. Lambris
H 指数: 127 · 论文数: 795
C
Capucine Pïcard
H 指数: 127 · 论文数: 576
N
Navdeep S. Chandel
H 指数: 125 · 论文数: 525
A
Ali Shilatifard
H 指数: 112 · 论文数: 418
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