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Discovery of WRN inhibitors as targeted therapy in the treatment of microsatellite unstable (MSI-H) tumors Schonemann, Wojciech; Ludwig-Slomczynska, Agnieszka; Dudek, Lukasz; Krol, Marcin; Farinone, Marco; Kulesza, Urszula; Jasnosz, Wojciech; Mac, Izabela; Zuchowicz, Karol; Wierzbicka, Katarzyna; Buchcic-Szychowska, Aleksandra; Gondela, Andrzej; Zagorska, Anna; Matuszewska, Oliwia; Sowinska, Marta; Nowogrodzki, Marcin; Girardi, Marianna; Paluch, Szymon; Sukhomlinova, Svitlana; Chlopek, Agata; Levenets, Iana; Kozlowska-Tomczyk, Kamila; Lagosz-Cwik, Katarzyna; Stoszko, Mateusz; Woroszylo, Szymon; Mikulski, Maciej; Jablonska, Justyna; Wisniewska, Magdalena; Palus-Chramiec, Katarzyna; Podkalicka-Golda, Paulina; Janiga, Anita; Sudol-Talaj, Sylwia; Sieprawska-Lupa, Magdalena; Miodek, Magdalena; Faber, Jacek; Starczak, Roza; Winnik, Bozena; Swirska, Agnieszka; Kowal-Chwast, Anna; Gogola, Dawid; Ratajczak, Sanja Novak; Dudek, Agata; Gaud, Nilesh; Satala, Grzegorz; Stachowicz, Agata; Swarbrick, Martin; Brzozka, Krzysztof; Zawadzka, Magdalena I. 分享 收藏
NOVEL, ORALLY ADMINISTERED HPK1 INHIBITORS DEMONSTRATE ANTI-TUMOR EFFICACY AND ENHANCED IMMUNE RESPONSE Chmielewski, Stefan; Kujawa, Maciej; Zimolag, Eliza; Galezowski, Michal; Gondela, Andrzej; Guzik, Pawel; Dudek, Agata; Szeremeta-Spisak, Joanna; Bugaj, Marta; Levenets, Iana; Nowogrodzki, Marcin; Girardi, Marianna; Zagorska, Anna; Wyrebek, Przemyslaw; Zastawna, Magdalena; Gibas, Agnieszka; Sudol, Sylwia; Levenets, Oleksandr; Swirski, Mateusz; Sasmal, Sujit; Radzimierski, Adam; Sowinska, Marta; Niedziejko, Paulina; Zuchowicz, Karol; Swarbrick, Martin; Gluza, Karolina; Kret, Patryk; Ogorek, Mateusz; Stanko, Dominika; Michalik, Kinga; Piatek, Agnieszka; Banaszak, Katarzyna; Podkowa, Adrian; Golas, Aniela; Littlewood, Peter; Brzozka, Krzysztof; Chielewski, Stefan 分享 收藏
Peptide-based urinary monitoring of fibrotic nonalcoholic steatohepatitis by mass-barcoded activity-based sensors Cazanave, Sophie C.; Warren, Andrew D.; Pacula, Maciej; Touti, Faycal; Zagorska, Anna; Gural, Nil; Huang, Eric K.; Sherman, Sarah; Cheema, Mehar; Ibarra, Sabrina; Bates, Jamie; Billin, Andrew N.; Liles, John T.; Budas, Grant R.; Breckenridge, David G.; Tiniakos, Dina; Ratziu, Vlad; Daly, Ann K.; Govaere, Olivier; Anstee, Quentin M.; Gelrud, Louis; Luther, Jay; Chung, Raymond T.; Corey, Kathleen E.; Winckler, Wendy; Bhatia, Sangeeta; Kwong, Gabriel A. 分享 收藏
Acetyl-CoA carboxylase inhibition disrupts metabolic reprogramming during hepatic stellate cell activation Bates, Jamie; Vijayakumar, Archana; Ghoshal, Sarani; Marchand, Bruno; Yi, Saili; Kornyeyev, Dmytro; Zagorska, Anna; Hollenback, David; Walker, Katie; Liu, Kathy; Pendem, Swetha; Newstrom, David; Brockett, Robert; Mikaelian, Igor; Kusam, Saritha; Ramirez, Ricardo; Lopez, David; Li, Li; Fuchs, Bryan C.; Breckenridge, David G. 分享 收藏
Differential regulation of hepatic physiology and injury by the TAM receptors Axl and Mer Zagorska, Anna; Traves, Paqui G.; Jimenez-Garcia, Lidia; Strickland, Jenna D.; Oh, Joanne; Tapia, Francisco J.; Mayoral, Rafael; Burrola, Patrick; Copple, Bryan L.; Lemke, Greg 分享 收藏
ASK1 inhibition reduces cell death and hepatic fibrosis in an Nlrp3 mutant liver injury model Schuster-Gaul, Susanne; Geisler, Lukas Jonathan; McGeough, Matthew D.; Johnson, Casey D.; Zagorska, Anna; Li, Li; Wree, Alexander; Barry, Vivian; Mikaelian, Igor; Jih, Lily J.; Papouchado, Bettina G.; Budas, Grant; Hoffman, Hal M.; Feldstein, Ariel E. 分享 收藏
Single-Cell Transcriptomics Uncovers Zonation of Function in the Mesenchyme during Liver Fibrosis 单细胞转录组学揭示肝纤维化期间间充质功能的分区 Dobie, Ross; Wilson-Kanamori, John R.; Henderson, Beth E. P.; Smith, James R.; Matchett, Kylie P.; Portman, Jordan R.; Wallenborg, Karolina; Picelli, Simone; Zagorska, Anna; Pendem, Swetha V.; Hudson, Thomas E.; Wu, Minnie M.; Budas, Grant R.; Breckenridge, David G.; Harrison, Ewen M.; Mole, Damian J.; Wigmore, Stephen J.; Ramachandran, Prakash; Ponting, Chris P.; Teichmann, Sarah A.; Marioni, John C.; Henderson, Neil C. 分享 收藏
Combination of an FXR agonist and an ACC inhibitor increases anti-fibrotic efficacy in rodent models of NASH Bates, J.; Hollenback, D.; Zagorska, A.; Budas, G.; Liles, J.; Liu, H.; Liu, K.; Kusam, S.; Brockett, R.; Newstrom, D.; Mikaelian, I.; Wang, T.; Ray, A.; Breckenridge, D. 分享 收藏
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Combination of an ASK1 inhibitor and FXR agonist increases efficacy in a mouse model of non-alcoholic steatohepatitis Liles, J. T.; Zagorska, A.; Hollenback, D.; Budas, G. R.; Liu, H.; Liu, K.; Brockett, R.; Shauf, A.; Tumas, D.; Breckenridge, D. G. 分享 收藏
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