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Sean Callaghan

Scripps Research Institute
H指数:14
被引数:2,719

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A blinded, prospective benchmark of in silico antibody discovery anchored to experimental affinity and developability

一项基于实验亲和力与可开发性的模拟抗体发现的盲法前瞻性基准研究

2026-08-190
OA
Germline-targeting HIV immunogen induces cross-neutralizing antibodies in outbred macaques

靶向生殖细胞的HIV免疫原在杂种猕猴中诱导交叉中和抗体

Immunity
IF26.3
2026-04-140
OAAI
Rapidly acquired HIV-1 neutralization breadth in a rhesus V2 apex knockin mouse model after a single bolus immunization

单次大剂量免疫后,恒河猴V2尖峰基因敲入小鼠模型中快速获得的HIV-1中和广度

2026-02-130
PRE
Broadly neutralizing anti-S2 antibodies protect against all three human betacoronaviruses that cause deadly disease

广泛中和的anti-S2抗体可预防导致致命疾病的所有三种人类 β 冠状病毒

IMMUNITY
IF26.3
2023-03-0149
OAAI
Molecular insights into antibody-mediated protection against the prototypic simian immunodeficiency virus
2022-09-063
OAAI
Broadly neutralizing antibodies to SARS-related viruses can be readily induced in rhesus macaques
2022-08-1010
OAAI
Targeted isolation of diverse human protective broadly neutralizing antibodies against SARS-like viruses
2022-06-0244
OA
A human antibody reveals a conserved site on beta-coronavirus spike proteins and confers protection against SARS-CoV-2 infection

人类抗体揭示了 β-冠状病毒刺突蛋白上的保守位点,并赋予了抵抗SARS-CoV-2感染的保护

2022-03-23119
OAAI
Cross-reactive serum and memory B-cell responses to spike protein in SARS-CoV-2 and endemic coronavirus infection
2021-05-19129
OAAI