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B

Barbara Mair

University of Toronto
H指数:17
被引数:1,655

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工作经历

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荣誉奖项

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Global genetic interaction network of a human cell maps conserved principles and informs functional interpretation of gene co-essentiality profiles

人类细胞的全球遗传互作网络绘制了保守原则并指导基因共必需性谱的功能解释

Cell
IF42.5
2026-04-270
PREAI
Maximilian Billmann; Michael Costanzo; Xiang Zhang; Arshia Z. Hassan; Mahfuzur Rahman; Kevin R. Brown; Katherine S. Chan; Amy Hin Yan Tong; Carles Pons; Henry N. Ward; Catherine Ross; Jolanda van Leeuwen; Michael Aregger; Keith A. Lawson; Barbara Mair; Amy F. Roth; Nesli E. Sen; Duncan T. Forster; Guihong Tan; Patricia Mero
SOS1 inhibitor BI-3406 shows in vivo antitumor activity akin to genetic ablation and synergizes with a KRASG12D inhibitor in KRAS LUAD

SOS1抑制剂BI-3406显示出类似基因敲除的在体抗肿瘤活性，并能与KRASG12D抑制剂协同作用，用于KRAS LUAD。

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
2025-03-120
OA
Baltanas, Fernando C.; Kramer-Drauberg, Maximilian; Garcia-Navas, Rosula; Patrucco, Enrico; Petrini, Ettore; Arnhof, Heribert; Olarte-SanJuan, Andrea; Rodriguez-Ramos, Pablo; Borrajo, Javier; Calzada, Nuria; Castellano, Esther; Mair, Barbara; Kostyrko, Kaja; Hofmann, Marco H.
A selective and orally bioavailable VHL-recruiting PROTAC achieves SMARCA2 degradation in vivo
NATURE COMMUNICATIONS
IF15.7
2022-10-1099
OAAI
Kofink, Christiane; Trainor, Nicole; Mair, Barbara; Woehrle, Simon; Wurm, Melanie; Mischerikow, Nikolai; Roy, Michael J.; Bader, Gerd; Greb, Peter; Garavel, Geraldine; Diers, Emelyne; McLennan, Ross; Whitworth, Claire; Vetma, Vesna; Rumpel, Klaus; Scharnweber, Maximilian; Fuchs, Julian E.; Gerstberger, Thomas; Cui, Yunhai; Gremel, Gabriela; Chetta, Paolo; Hopf, Stefan; Budano, Nicole; Rinnenthal, Joerg; Gmaschitz, Gerhard; Mayer, Moriz; Koegl, Manfred; Ciulli, Alessio; Weinstabl, Harald; Farnaby, William
Interrogation of cancer gene dependencies reveals paralog interactions of autosome and sex chromosome-encoded genes
CELL REPORTS
IF6.9
2022-04-0126
OA
Koeferle, Anna; Schlattl, Andreas; Hoermann, Alexandra; Thatikonda, Venu; Popa, Alexandra; Spreitzer, Fiona; Ravichandran, Madhwesh C.; Supper, Verena; Oberndorfer, Sarah; Puchner, Teresa; Wieshofer, Corinna; Corcokovic, Maja; Reiser, Christoph; Woehrle, Simon; Popow, Johannes; Pearson, Mark; Martinez, Javier; Weitzer, Stefan; Mair, Barbara; Neumueller, Ralph A.
Digital microfluidic isolation of single cells for -Omics
NATURE COMMUNICATIONS
IF15.7
2020-11-11117
OAAI
Lamanna, Julian; Scott, Erica Y.; Edwards, Harrison S.; Chamberlain, M. Dean; Dryden, Michael D. M.; Peng, Jiaxi; Mair, Barbara; Lee, Adam; Chan, Calvin; Sklavounos, Alexandros A.; Heffernan, Austin; Abbas, Farhana; Lam, Charis; Olson, Maxwell E.; Moffat, Jason; Wheeler, Aaron R.
Essential Gene Profiles for Human Pluripotent Stem Cells Identify Uncharacterized Genes and Substrate Dependencies

人类多能干细胞的必需基因谱识别未表征的基因和底物依赖性

CELL REPORTS
IF6.9
2019-04-0193
OAAI
Mair, Barbara; Tomic, Jelena; Masud, Sanna N.; Tonge, Peter; Weiss, Alexander; Usaj, Matej; Tong, Amy Hin Yan; Kwan, Jamie J.; Brown, Kevin R.; Titus, Emily; Atkins, Michael; Chan, Katherine S. K.; Munsie, Lise; Habsid, Andrea; Han, Hong; Kennedy, Marion; Cohen, Brenda; Keller, Gordon; Moffat, Jason
Discovery of a Highly Selective Cell-Active Inhibitor of the Histone Lysine Demethylases KDM2/7

组蛋白赖氨酸脱甲基酶KDM2/7的高选择性细胞活性抑制剂的发现

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
IF16.9
2017-11-0731
OAAI
Gerken, Philip A.; Wolstenhulme, Jamie R.; Tumber, Anthony; Hatch, Stephanie B.; Zhang, Yijia; Mueller, Susanne; Chandler, Shane A.; Mair, Barbara; Li, Fengling; Nijman, Sebastian M. B.; Konietzny, Rebecca; Szommer, Tamas; Yapp, Clarence; Fedorov, Oleg; Benesch, Justin L. P.; Vedadi, Masoud; Kessler, Benedikt M.; Kawamura, Akane; Brennan, Paul E.; Smith, Martin D.
Targeting a cell state common to triple-negative breast cancers
MOLECULAR SYSTEMS BIOLOGY
IF7.7
2015-02-1923
OAAI
Muellner, Markus K.; Mair, Barbara; Ibrahim, Yasir; Kerzendorfer, Claudia; Lechtermann, Hannelore; Trefzer, Claudia; Klepsch, Freya; Mueller, Andre C.; Leitner, Ernestine; Macho-Maschler, Sabine; Superti-Furga, Giulio; Bennett, Keiryn L.; Baselga, Jose; Rix, Uwe; Kubicek, Stefan; Colinge, Jacques; Serra, Violeta; Nijman, Sebastian M. B.

研究方向

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J
Jason Moffat
H 指数:73论文数:602被引数:3.0万
S
Sebastian Nijman
H 指数:30论文数:106被引数:9,707
A
Amy H.Y. Tong
H 指数:53论文数:203被引数:1.8万
M
Markus K. Muellner
H 指数:12论文数:20被引数:1,175
C
Claudia Kerzendorfer
H 指数:15论文数:35被引数:1,173
V
Violeta Serra
H 指数:71论文数:872被引数:2.1万
K
Katherine Chan
H 指数:17论文数:114被引数:1,443
J
Javier Martı̂nez
H 指数:36论文数:226被引数:8,305
S
Stefan Kubicek
H 指数:54论文数:414被引数:1.4万
T
Tomasz Konopka
H 指数:13论文数:44被引数:1,998