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C

Calixto-Hope G. Lucas

Johns Hopkins University
H指数:24
被引数:1,855

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The CoREST complex inhibitor, corin, decreases tumor growth, increases cellular differentiation and extends lifespan in ATRT xenograft models

CoREST复合物抑制剂corin可降低ATRT异种移植模型的肿瘤生长，增加细胞分化并延长寿命

Neuro-Oncology
IF13.4
2026-07-210
PRE
Anupa Geethadevi; Nikhil Vaidya; Robert J Fisher; Tyler R Findlay; Yiming Deng; Khoa Pham; Vikas Kumar; Samuel Beck; Jun Choe; Shiyu Liu; Calixto-Hope G Lucas; Charles G Eberhart; Jinchong Xu; Philip A Cole; Jeffrey Rubens; Marianne Collard; Eric H Raabe; Rhoda M Alani
Androgen activity in the male embryonic hindbrain drives lethal PFA ependymoma

雄性胚胎后脑中的雄激素活性驱动致死性PFA室管膜瘤

Nature
IF48.5
2026-03-250
OAAI
Jiao Zhang; Winnie Ong; Alexandra Rasnitsyn; Ricardo Daniel Gonzalez; Rodrigo Lopez Gutierrez; Polina Balin; Amr Saadeldin; Xiaochong Wu; Maria C. Vladoiu; Vicente Santa-Maria Lopez; Fernando Gonzalez-Salinas; Navneesh Yadav; Dinesh Mohanakrishnan; Kannan Boosi Narayana Rao; Raja Gopal Reddy Mooli; Hinda Najem; Sebastian Pacheco; Kaitlin Kharas; Cory Richman; David Przelicki; Evan Y. Wang; Haipeng Su; Rachel Naomi Curry; Runze Yang; Michelle Masayo Kameda-Smith; Bryn Livingston; David Scott; Zaili Luo; Mingyang Xia; Namal Abeysundara; Anders W. Erickson; Ncedile Mankahla; Lucas ZhongMing Hu; Chu Pan; Raul Suarez; Ning Huang; Yihao Wu; Hao Wang; Tajana Douglas; Jonelle Pallota; Steven Hébert; Karen Ng; Krystin Mantione; Heather Whetstone; Hassaan Maan; Hussein Lakkis; Juyeun Lee; Sadeesh K. Ramakrishnan; Yanxin Pei; Yujie Tang; Frank Y. Lin; Guillermo Aldave; Marco Gallo; Robert M. Friedlander; Faiyaz Notta; Laura K. Donovan; Murali Chintagumpala; Bo Wang; Yun Li; Daniel D. De Carvalho; Zhaolei Zhang; Ying Mao; Wei Hua; Charles Eberhart; Calixto-Hope G. Lucas; Sriram Venneti; Poul H. Sorensen; Alberto Delaidelli; Hao Li; Wenhao Zhou; Jason Kirk; Dean G. Tang; Tao Jiang; Hailong Liu; Justin D. Lathia; Hiromichi Suzuki; Jeremy N. Rich; Lincoln D. Stein; Nada Jabado; Vijay Ramaswamy; Q. Richard Lu; Amy B. Heimberger; Craig Daniels; Kulandaimanuvel Antony Michealraj; Claudia L. Kleinman; Michael D. Taylor
DUAL CHECKPOINT BLOCKADE WITH ANTI-PD-1 AND ANTI-LAG-3 DRIVES EXPANSION AND EXHAUSTION OF GZMK plus TUMOR-REACTIVE T CELL CLONES IN GLIOBLASTOMA

双检查点阻断（抗PD-1和抗LAG-3）促进GZMK<sup>+</sup>肿瘤反应性T细胞克隆的扩增与耗竭，见于胶质母细胞瘤

NEURO-ONCOLOGY
IF13.4
2025-11-010
OAAI
Wang, Mingshuang; Fu, Yuntian; Bom, Sadhana; Zhang, Ming; Lucas, Calixto-Hope; Weingart, Jon; Yegnasubramanian, Vasan; Lim, Michael; Pardoll, Drew; Zhang, Nancy; Jackson, Christina
The single cell landscape of NF1-associated gliomas pre- and post-treatment and comparison to their sporadic counterparts

NF1相关胶质瘤治疗前后单细胞景观及其与散发型对照的比较

NEURO-ONCOLOGY
IF13.4
2025-11-010
OAAI
Gupta, Rohit; Ravindranathan, Ajay; Wu, Jasper; Lucas, Calixto-Hope; Shai, Anny; Nazarian, Javad; Campen, Cynthia; Partap, Sonia; Omuro, Antonio; Gephart, Melanie Hayden; Lim, Michael; Butowski, Nicholas; Berger, Mitchel; Reddy, Alyssa; Phillips, Joanna; Solomon, David
High-grade astrocytoma with piloid features (HGAP) comprehensive update: histological grading, molecular markers and clinical outcomes

高级别毛细胞样星形细胞瘤(HGAP)综合更新：组织学分级、分子标记物和临床结局

NEURO-ONCOLOGY
IF13.4
2025-11-010
OAAI
Zhang, Shuodan; Singh, Omkar; Dazelle, Karen; Abdullaev, Zied; Cimino, Patrick J.; Lucas, Calixto-Hope; Cathcart, Sahara J.; Mount, Christopher; Lakis, Nelli S.; Pytel, Peter; Goodwill, Vanessa S.; Macaulay, Robert J. B.; Mcdonald, William; Seidman, Roberta J.; Wood, Matthew D.; Bharani, Krishna L.; Neltner, Janna; Richard, Hope; Chang, Koping; Szymanski, Linda J.; Yip, Stephen; Mukherjee, Abir; Neto, Osorio Lopes Abath; Sharma, Suash; Green, Richard; Brown, Daniel; Gubbiotti, Maria; Eschbacher, Jennifer; Gokden, Murat; Vincentelli, Cristina; Yong, William; Lee, Julieann C.; Aldape, Kenneth
Neuropath-IHC: a deep neural network for virtual immunohistochemistry from digital whole slide images of CNS tumors

神经病理-IHC：一种用于中枢神经系统肿瘤数字全切片图像虚拟免疫组化分析的深度神经网络

NEURO-ONCOLOGY
IF13.4
2025-11-010
OAAI
Dampier, Christopher H.; Lalchungnunga, Fnu; Hoang, Danh-Tai; Shulman, Eldad D.; Abdullaev, Zied; Li, Bochong; Luo, Zhirui; Singh, Omkar; Wu, Zhichao; Pearce, Thomas M.; Marker, Daniel F.; Horbinski, Craig; Lucas, Calixto-Hope G.; Cimino, Patrick J.; Nasrallah, Maclean P.; Quezado, Martha; Chung, Hye-Jung; Yefet, Leeor; Zadeh, Gelareh; Brandner, Sebastian; Ruppin, Eytan; Aldape, Kenneth
BraTS-Pathology 2024: Insights and Future Directions Informed by the AI-RANO & RANO-RGP Effort to Assess Glioblastoma Heterogeneity

BraTS-Pathology 2024：基于AI-RANO与RANO-RGP评估胶质母细胞瘤异质性的见解与未来方向

NEURO-ONCOLOGY
IF13.4
2025-11-010
OAAI
Thakur, Siddhesh; Malec, Sylwia; Pitarc, Carla; Linardos, Akis; Innani, Shubham; Adap, Sanyukta; Faghani, Shahriar; Moassefi, Mana; Nasrallah, Maclean; Ahrendsen, Jared; Barresi, Valeria; Gubbiotti, Maria; Lopez, Giselle; Lucas, Calixto-Hope G.; Chung, Verena; Karargyris, Alexandros; Kassem, Hasan; Miller, Michael; Pati, Sarthak; Baheti, Bhakti; Wodzinski, Marek; Muller, Henning; Zhang, Juexin; Weng, Ying; Chen, Ke; Kumar, Rithik; Vinit, Vinit; Arora, Madhav; Dhingra, Twinkle; Zahra, Syed Rameem; Gupta, Ankur; Sandino, Alvaro; Tiwari, Pallawi; Cooper, Lee; Huse, Jason; Bell, Robert; Bakas, Spyridon
Implementing a centralized, institution-wide neuro-oncology database to advance precision neuro-oncology and multidisciplinary research

实施一个集中化、覆盖全机构的神经肿瘤学数据库，以推动精准神经肿瘤学和多学科研究

NEURO-ONCOLOGY
IF13.4
2025-11-010
OAAI
Sherief, Mohamed; Botsis, Taxiarchis; Chang, Michael; Bettegowda, Chetan; Croog, Victoria; Holdhoff, Matthias; Kamson, David O.; Lucas, Calixto-Hope G.; Mukherjee, Debraj; Rincon-Torroella, Jordina; Sahebjam, Solmaz; Anagnostou, Valsamo; Schreck, Karisa C.
Neuropath-AI, a histopathology-based deep learning classifier for CNS tumors, achieves and improves human neuropathologist-level performance

Neuropath-AI，一种基于组织病理学的深度学习分类器，用于CNS肿瘤，实现了并提高了人类神经病理学家的水平。

NEURO-ONCOLOGY
IF13.4
2025-11-010
OAAI
Lalchungnunga, H.; Dampier, Christopher H.; Singh, Omkar; Hoang, Danh-Tai; Shulman, Eldad D.; Abdullaev, Zied; Li, Bochong; Luo, Zhirui; Pearce, Thomas; Marker, Daniel F.; Horbinski, Craig; Lucas, Calixto-Hope G.; Cimino, Patrick J.; Nasrallah, MacLean P.; Quezado, Martha; Chung, Hye-Jung; Yefet, Leeor; Zadeh, Gelareh; Brandner, Sebastian; Ruppin, Eytan; Aldape, Kenneth
Radiologic characterization and clinical management of multinodular and vacuolating neuronal tumor (MVNT): a retrospective institutional cohort study

多结节和空泡神经元肿瘤（MVNT）的放射学特征与临床管理：一项回顾性机构队列研究

Journal of Neuro-Oncology
IF3.1
2025-10-300
PRE
Austin Carmichael; Umar Arshad; Daniel Martinez Heinemann; Sai Chandan Reddy; Anita Kalluri; Antolin Serrano-Farias; Praneethkumar Madhu; Dhairya A. Lakhani; Haris Sair; Karisa C. Schreck; Calixto-Hope Lucas; Ignacio Gonzalez-Gomez; George I. Jallo; Chetan Bettegowda; Jordina Rincon-Torroella
IL6 UNDERLIES MICROENVIRONMENT IMMUNOSUPPRESSION AND RESISTANCE TO THERAPY IN GLIOBLASTOMA

IL6 是胶质母细胞瘤微环境免疫抑制和耐药性的基础

NEURO-ONCOLOGY
IF13.4
2025-10-010
OA
Young, J. S.; Cho, N.; Lucas, C. G.; Seo, K.; Najem, H.; Mirchia, K.; Chen, W. C.; Zakimi, N.; Daggubati, V; Casey-Clyde, T.; Nguyen, M. P.; Chen, A.; Phillips, J. J.; Ozawa, T.; Aghi, M. K.; Taylor, J. W.; DeRisi, J. L.; Bhaduri, A.; Heimberger, A.; Berger, M. S.; Butowski, N.; Spitzer, M. H.; Raleigh, D. R.
Selective inhibition of BRAF and CRAF sensitizes NF1-deficient malignant peripheral nerve sheath tumors to MEK inhibitors

选择性抑制BRAF和CRAF使NF1缺乏的恶性周围神经鞘瘤对MEK抑制剂更敏感

Molecular Medicine
IF6.4
2025-09-290
OAAI
Jiawan Wang; Arnab Sarkar; Natalia Garcia; Lindy Zhang; Ana Calizo; Alla Lisok; Katia Campos; Funan He; Nishanth Punjaala; Teresa Marple; Kai Pollard; Siyuan Zheng; Calixto-Hope G. Lucas; Vesselina G. Cooke; Christine A. Pratilas; Angelina V. Vaseva

研究方向

暂未获取到该数据
A
Arie Perry
H 指数:119论文数:907被引数:7.7万
D
David R. Raleigh
H 指数:53论文数:530被引数:1.1万
D
David A. Solomon
H 指数:76论文数:545被引数:2.2万
W
William Chen
H 指数:49论文数:448被引数:8,573
M
Melike Pekmezci
H 指数:46论文数:314被引数:1.0万
S
Stephen T. Magill
H 指数:36论文数:294被引数:4,719
K
Karisa C. Schreck
H 指数:20论文数:185被引数:2,222
J
Joanna J. Phillips
H 指数:84论文数:645被引数:2.6万
N
Nancy Ann Oberheim Bush
H 指数:28论文数:164被引数:3,721
K
Kanish Mirchia
H 指数:16论文数:134被引数:1,082