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何

何治 (Zhi He)

jiaxing university邮箱:hezhi2023@zjxu.edu.cn

H指数:24

被引数:1,756

个人简介

现任三峡大学医学院院长，教授，博士/硕士研究生导师。2008年获华中科技大学药理学专业博士学位，2012-2013年德国美因茨大学医学中心访问学者。主要从事脑卒中、药物成瘾等神经系统疾病发病机理及相关防治药物的研究，围绕HCN通道与脑缺血及药物成瘾、ALPHA肾上腺素受体与脑缺血、天然药物的抗脑缺血作用及机制等研究领域开展工作。

教育背景

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工作经历

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荣誉奖项

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Multi-objective management of alkali/alkaline earth metals and phosphorus in sludge hydrothermal pretreatment with process water recycling: Based on machine learning and path analysis

基于机器学习和路径分析的污泥水热预处理中碱/碱土金属和磷的多目标管理：工艺水回用

Fundamental Research

IF6.3

2026-07-230

OA

Mechanisms of Longdan Xiegan decoction–aggravated D-Galactosamine–induced liver injury: Gut microbiota–mediated geniposide biotransformation and TLR4/NF-κB pathway activation

龙胆泻肝汤加重D-半乳糖胺诱导的肝损伤机制：肠道菌群介导的栀子苷生物转化及TLR4/NF-κB通路激活

IF2.6

2026-07-170

PRE

Harpagide attenuates cerebral ischemic injury by modulating mitochondrial calcium homeostasis associated with the AMPK–MCU axis

哈帕苷通过调节与AMPK–MCU轴相关的线粒体钙稳态来减轻脑缺血损伤

Scientific Reports

IF3.9

2026-06-010

OAAI

Clonidine protects rat hippocampal and cortical neurons from oxygen-glucose deprivation and reoxygenation-induced injury through HCN Channels

Clonidine通过HCN通道保护大鼠海马和皮层神经元免受氧糖剥夺及复氧诱导的损伤。

Scientific Reports

IF3.9

2026-03-260

OAAI

ZD7288 ameliorates long-term cerebral ischemia reperfusion-induced deterioration of spatial memory by regulating the expressions of NMDA receptor subunits in rats

ZD7288通过调节NMDA受体亚基的表达，改善大鼠长期脑缺血再灌注诱导的空间记忆恶化。

SCIENTIFIC REPORTS

IF3.9

2025-05-250

OA

Intensified Enrichment and Leaching Strategy of Phosphorus in Sewage Sludge via Species-Targeted Conversion

通过物种靶向转化强化污水污泥中磷的富集与浸取策略

ENVIRONMENTAL SCIENCE & TECHNOLOGY

IF11.3

2025-05-020

PRE

Gallic acid relieved bortezomib-induced peripheral neurotoxicity by restoring Schwann cell lysosomal activity

TOXICOLOGICAL SCIENCES

IF4.1

2025-04-010

PRE

Toona sinensis fruit polyphenols alleviate cerebral ischemia-reperfusion injury in rats by inhibiting MAPK signaling pathways and NLRP3 inflammasome/pyroptosis

香椿果实多酚通过抑制MAPK信号通路和NLRP3炎症小体/焦亡来减轻大鼠脑缺血再灌注损伤

JOURNAL OF ETHNOPHARMACOLOGY

IF5.4

2025-02-011

PRE

Association of dipeptidyl peptidase-4 with Alzheimer's disease: A new therapeutic prospect

JOURNAL OF ALZHEIMERS DISEASE

IF3.1

2025-01-080

PRE

The alpha2-adrenergic receptor agonist clonidine protects against cerebral ischemia/reperfusion induced neuronal apoptosis in rats

METABOLIC BRAIN DISEASE

IF3.5

2024-06-042

OA

Inhibition of hyperpolarization-activated cyclic nucleotide-gated cation channel attenuates cerebral ischemia reperfusion-induced impairment of learning and memory by regulating apoptotic pathway

METABOLIC BRAIN DISEASE

IF3.5

2023-10-201

PRE

Clonidine ameliorates cerebral ischemia-reperfusion injury by up-regulating the GluN3 subunits of NMDA receptor

METABOLIC BRAIN DISEASE

IF3.5

2022-06-216

PRE

Mitochondria as a therapeutic target for ischemic stroke

FREE RADICAL BIOLOGY AND MEDICINE

IF8.2

2020-01-01187

PREAI

Clonidine preconditioning improved cerebral ischemia-induced learning and memory deficits in rats via ERK1/2-CREB/NF-κB-NR2B pathway

EUROPEAN JOURNAL OF PHARMACOLOGY

IF4.7

2018-01-0117

PREAI

Clonidine preconditioning alleviated focal cerebral ischemic insult in rats via up-regulating p-NMDAR1 and down-regulating NMDAR2A/p-NMDAR2B

EUROPEAN JOURNAL OF PHARMACOLOGY

IF4.7

2016-12-0115

PREAI

The Impact of Biologically Effective Dose on Keloid Recurrence After Postoperative Electron Beam Radiation Therapy in African American Patients

INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS

IF6.5

2015-11-011

OAAI

Clonidine ameliorates cognitive impairment induced by chronic cerebral hypoperfusion via up-regulation of the GABABR1 and GAD67 in hippocampal CA1 in rats

PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

IF2.5

2015-05-0114

PREAI

Imbalance of HCN1 and HCN2 expression in hippocampal CA1 area impairs spatial learning and memory in rats with chronic morphine exposure

PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

IF3.9

2015-01-0127

PREAI

Piracetam Ameliorated Oxygen and Glucose Deprivation-Induced Injury in Rat Cortical Neurons Via Inhibition of Oxidative Stress, Excitatory Amino Acids Release and P53/Bax

CELLULAR AND MOLECULAR NEUROBIOLOGY

IF4.8

2014-02-2623

PREAI

Nuclear MTA1 overexpression is associated with aggressive prostate cancer, recurrence and metastasis in African Americans

SCIENTIFIC REPORTS

IF3.9

2013-07-3148

OAAI