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S

Santiago Vernia

imperial college london
H指数:26
被引数:2,290

个人简介

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教育背景

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工作经历

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荣誉奖项

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Myc sustains sex-biased organ zonation in the Drosophila intestine

Myc维持果蝇肠道中性别偏向性器官分区

Developmental Cell
IF8.7
2026-07-010
PRE
Amourda, Christopher; Blackie, Laura; Gaspar, Pedro; Martin-Coll, Laura; Prasad, Anadika R.; House, Andrew H.; Holopainen, Minna; Ruhanen, Hanna; Lamichane, Nicole; Hadjieconomou, Dafni; Ameku, Tomotsune; Mineo, Alessandro; Coxhead, Milly; Soler-Saez, Irene; Galiana-Rosello, Cristina; Garcia-Garcia, Francisco; Wang, Yi-Fang; Alexandre, Cyrille; Hietakangas, Ville; Kakela, Reijo; Vernia, Santiago; Miguel-Aliaga, Irene
Electrophilic compound screening identifies GPX4-dependent ferroptosis as a senescence vulnerability

亲电化合物筛选鉴定出GPX4依赖性铁死亡为衰老的易损性

Nature Cell Biology
IF19.1
2026-04-240
OAAI
Mariantonietta D’Ambrosio; Matthew E. H. White; Efthymios S. Gavriil; Laura Bousset; Jodie Birch; Aleksandra Gruevska; Emiliano Pasquini; Manuel Colucci; Winnie Fong; Simone Mosole; Aurora Valdata; Dimitris Veroutis; Katie Tyson; Vikas Ranvir; Sandra Prokosch; Joaquim Pombo; Aoki Ardisson; Sanjay Khadayate; George Young; Alex Montoya; Georgia Roumelioti; Jack Houghton; Jianan Lu; Pavel V. Shliaha; Elena De Vita; Santiago Vernia; Vassilis G. Gorgoulis; Suchira Gallage; Mathias Heikenwälder; Zoe Hall; Andrea Alimonti; Iain A. McNeish; Edward W. Tate; Jesús Gil
Spliceosome induction is a druggable dependency of RAS-driven senescence and cancer

剪接体诱导是RAS驱动的衰老和癌症的药物依赖性

Nature Communications
IF15.7
2026-04-150
OAAI
Verena Wagner; Laura Bousset; Mariana Ascensão-Ferreira; Bin Sun; José Efren Barragan Avila; Alexandre Kaizeler; Rita Martins-Silva; Mohammad Rahbari; Mirian Fernández-Vaquero; Scott Haston; Michele Tinti; Joaquim Pombo; Sanjay Khadayate; Susanne Roth; Christian M. Schürch; Juan Pedro Martínez-Barbera; Anat Bahat; Keng Boon Wee; Jennifer P. Morton; Nisar Malek; Andrew J. Innes; Santiago Vernia; Nuno L. Barbosa-Morais; Suchira Gallage; Mathias Heikenwalder; Jesús Gil
Correction: Widespread 3′UTR capped RNAs derive from G-rich regions in proximity to AGO2 binding sites

修正：广泛存在的3′UTR加帽RNA来源于AGO2结合位点附近的G富集区域

BMC Biology
IF4.5
2026-03-300
OAAI
Nejc Haberman; Holly Digby; Rupert Faraway; Rebecca Cheung; Anob M. Chakrabarti; Andrew M. Jobbins; Callum Parr; Kayoko Yasuzawa; Takeya Kasukawa; Chi Wai Yip; Masaki Kato; Hazuki Takahashi; Piero Carninci; Santiago Vernia; Jernej Ule; Christopher R. Sibley; Aida Martinez-Sanchez; Boris Lenhard
High-Throughput Proteomics Sample Preparation Using a 96-Channel Pipettor and Magnetic Pin Device

使用96通道移液器和磁力针装置的高通量蛋白质组学样品制备

Journal of Proteome Research
IF3.6
2026-02-010
PRE
Roumelioti, Georgia; Montoya, Alex; Fisher, Gemma L. M.; Navarro, Eneko Pascual; Woods, Angela; Bennett, Jane; Navaratnam, Naveenan; Gonzalez-Carvajal, Oliver; Birch, Jodie; Pyman, Elizabeth; Yu, Sijia; Gruevska, Aleksandra; Vuillemenot, Luc-Alban; Lushchak, Oleh; Hall, Zoe; Barr, Alexis R.; Speck, Christian; Vernia, Santiago; Scott, William R.; Gil, Jesus; Aragon, Luis; Fets, Louise; Carling, David; Shliaha, Pavel V.
HNF1A and A1CF coordinate a beta cell transcription-splicing axis that is disrupted in type 2 diabetes

HNF1A和A1CF协调一个在2型糖尿病中失调的β细胞转录-剪接轴。

Cell Metabolism
IF30.9
2025-08-060
OAAI
Edgar Bernardo; Matías Gonzalo De Vas; Diego Balboa; Mirabai Cuenca-Ardura; Sílvia Bonàs-Guarch; Mercè Planas-Fèlix; Fanny Mollandin; Miquel Torrens-Dinarès; Miguel Angel Maestro; Javier García-Hurtado; Sonia Moratinos; Philippe Ravassard; Haiqiang Dou; Holger Heyn; Alexander van Oudenaarden; Nathalie Groen; Eelco de Koning; Christian Conrad; Roland Eils; Santiago Vernia; Patrik Rorsman; Jorge Ferrer
Ribosomal S6 kinase 1 regulates inflammaging via the senescence secretome

核糖体S6激酶1通过衰老分泌组调节炎症

NATURE AGING
IF19.4
2024-08-291
OAAI
Gallage, Suchira; Irvine, Elaine E.; Barragan Avila, Jose Efren; Reen, Virinder; Pedroni, Silvia M. A.; Duran, Imanol; Ranvir, Vikas; Khadayate, Sanjay; Pombo, Joaquim; Brookes, Sharon; Heide, Danijela; Dharmalingham, Gopuraja; Choudhury, Agharul I.; Singh, Indrabahadur; Herranz, Nicolas; Vernia, Santiago; Heikenwalder, Mathias; Gil, Jesus; Withers, Dominic J.
COPI vesicle formation and N-myristoylation are targetable vulnerabilities of senescent cells

COPI囊泡形成和N-肉豆蔻酰化是衰老细胞的可靶向脆弱性

NATURE CELL BIOLOGY
IF19.1
2023-11-2712
OAAI
McHugh, Domhnall; Sun, Bin; Gutierrez-Munoz, Carmen; Hernandez-Gonzalez, Fernanda; Mellone, Massimiliano; Guiho, Romain; Duran, Imanol; Pombo, Joaquim; Pietrocola, Federico; Birch, Jodie; Kallemeijn, Wouter W.; Khadayate, Sanjay; Dharmalingam, Gopuraja; Vernia, Santiago; Tate, Edward W.; Martinez-Barbera, Juan Pedro; Withers, Dominic J.; Thomas, Gareth J.; Serrano, Manuel; Gil, Jesus
Endothelial sensing of AHR ligands regulates intestinal homeostasis
Nature
IF48.5
2023-08-160
OAAI
Benjamin G. Wiggins; Yi-Fang Wang; Alice Burke; Nil Grunberg; Julia M. Vlachaki Walker; Marian Dore; Catherine Chahrour; Betheney R. Pennycook; Julia Sanchez-Garrido; Santiago Vernia; Alexis R. Barr; Gad Frankel; Graeme M. Birdsey; Anna M. Randi; Chris Schiering
Liver RBFOX2 regulates cholesterol homeostasis via Scarb1 alternative splicing in mice
NATURE METABOLISM
IF20.8
2022-12-1920
OAAI
Paterson, Helen A. B.; Yu, Sijia; Artigas, Natalia; Prado, Miguel A.; Haberman, Nejc; Wang, Yi-Fang; Jobbins, Andrew M.; Pahita, Elena; Mokochinski, Joao; Hall, Zoe; Guerin, Maryse; Paulo, Joao A.; Ng, Soon Seng; Villarroya, Francesc; Rashid, Sheikh Tamir; Le Goff, Wilfried; Lenhard, Boris; Cebola, Ines; Finley, Daniel; Gygi, Steven P.; Sibley, Christopher R.; Vernia, Santiago
Phosphorylation of RXRa mediates the effect of JNK to suppress hepatic FGF21 expression and promote metabolic syndrome

RXRa磷酸化介导JNK抑制肝脏FGF21表达促进代谢综合征

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
2022-10-256
OAAI
Vernia, Santiago; Lee, Alexandra; Kennedy, Norman J.; Han, Myoung Sook; Isasa, Marta; Cavanagh-Kyros, Julie; Roy, Armanda; Syed, Aafreen; Chaudhry, Shanzah; Edwards, Yvonne J. K.; Gygi, Steven P.; Gao, Guangping; Davis, Roger J.
Steroidogenic control of liver metabolism through a nuclear receptor-network

通过核受体网络控制肝脏代谢的类固醇生成

MOLECULAR METABOLISM
IF6.6
2019-12-0114
OAAI
Milona, Alexandra; Massafra, Vittoria; Vos, Harmjan; Naik, Jyoti; Artigas, Natalia; Paterson, Helen A. B.; Bijsmans, Ingrid T. G. W.; Willemsen, Ellen C. L.; Pittol, Jose M. Ramos; Miguel-Aliaga, Irene; Bosma, Piter; Burgering, Boudewijn M. T.; Williamson, Catherine; Vernia, Santiago; Dhillo, Waljit S.; van Mil, Saskia W. C.; Owen, Bryn M.
Cardiac glycosides are broad-spectrum senolytics

强心苷是广谱抗衰老药

NATURE METABOLISM
IF20.8
2019-10-21225
OAAI
Guerrero, Ana; Herranz, Nicolas; Sun, Bin; Wagner, Verena; Gallage, Suchira; Guiho, Romain; Wolter, Katharina; Pombo, Joaquim; Irvine, Elaine E.; Innes, Andrew J.; Birch, Jodie; Glegola, Justyna; Manshaei, Saba; Heide, Danijela; Dharmalingam, Gopuraja; Harbig, Jule; Olona, Antoni; Behmoaras, Jacques; Dauch, Daniel; Uren, Anthony G.; Zender, Lars; Vernia, Santiago; Martinez-Barbera, Juan Pedro; Heikenwalder, Mathias; Withers, Dominic J.; Gil, Jesus

研究方向

暂未获取到该数据
P
Pascual Sanz
H 指数:45论文数:187被引数:8,773
R
Roger J. Davis
H 指数:166论文数:852被引数:12.6万
S
Santiago Rodrı́guez de Córdoba
H 指数:73论文数:360被引数:2.8万
J
Jesús Gil
H 指数:72论文数:232被引数:2.9万
O
Olga Criado‐García
H 指数:14论文数:20被引数:1,376
S
Suchira Gallage
H 指数:18论文数:49被引数:2,943
J
Julie Cavanagh-Kyros
H 指数:15论文数:22被引数:1,249
E
Erwin Knecht
H 指数:45论文数:162被引数:1.7万
C
Carmen Aguado
H 指数:24论文数:120被引数:1,932
D
Dominic J. Withers
H 指数:60论文数:158被引数:1.9万