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朱

朱益 (Yi Zhu)

Mayo Clinic
H指数:39
被引数:1.8万

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Senloytics, dasatinib plus quercetin, reduce kidney inflammation, senescent cell abundance, and injury while restoring geroprotective factors in murine diabetic kidney disease

Senloyatics，达沙替尼加槲皮素，减少肾脏炎症，衰老细胞丰度和损伤，同时恢复小鼠糖尿病肾病的老年保护因子

eBioMedicine
IF10.8
2026-01-200
OAAI
Xiaohui Bian; Zachary K. Snow; Caroline J. Zinn; Anastasia L. Bratulin; Khaled M. Elhusseiny; Tamar Tchkonia; James L. Kirkland; Yi Zhu; Sundeep Khosla; Seo Rin Kim; Lilach O. Lerman; LaTonya J. Hickson
Senolytic-Resistant Senescent Cells Have a Distinct SASP Profile and Functional Impact: The Path to Developing Senosensitizers
AGING CELL
IF7.1
2026-01-010
OAAI
Tripathi, Utkarsh; Suda, Masayoshi; Kulshreshtha, Vagisha; Piatkowski, Bryan T.; Palmer, Allyson K.; Giorgadze, Nino; Inman, Christina; Gasek, Nathan; Xu, Ming; Johnson, Kurt O.; Pirtskhalava, Tamar; Chaib, Selim; Langhi Prata, Larissa P. G.; Zhu, Yi; Kandhaya-pillai, Renuka; Tullius, Stefan G.; Wyles, Saranya P.; Majji, Rambabu; Yalamanchili, Hari Krishna; Allison, David B.; Tchkonia, Tamar; Kirkland, James L.
Endothelial senescent-cell-specific clearance alleviates metabolic dysfunction in obese mice

内皮衰老细胞特异性清除缓解肥胖小鼠的代谢功能障碍

Cell Metabolism
IF30.9
2025-11-200
PRE
Masayoshi Suda; Selim Chaib; Larissa G.P. Langhi Prata; Yi Zhu; Utkarsh Tripathi; Karl H. Paul; Allyson K. Palmer; Tamar Pirtskhalava; Vagisha Kulshreshtha; Christina L. Inman; Kurt O. Johnson; Nino Giorgadze; Runqing Huang; Carolyn M. Roos; Luisa F. Leon-Sanchez; Jordan D. Miller; Thomas White; Linshan Laux; Laura J. Niedernhofer; Paul D. Robbins
IL-2-loaded liposomes modified with sorafenib derivative exert a synergistic anti-melanoma effect via improving tumor immune microenvironment and enhancing antiangiogenic activity

负载IL-2的脂质体经索拉非尼衍生物修饰后，可通过改善肿瘤免疫微环境并增强抗血管生成活性，发挥协同抗黑色素瘤作用。

ASIAN JOURNAL OF PHARMACEUTICAL SCIENCES
IF11.9
2025-01-010
OAAI
Huang, Xuan; Kuerban, Kudelaidi; Fan, Jajun; Pan, Danjie; Chen, Huaning; Liu, Jiayang; Wang, Songna; Ju, Dianwen; Zhu, Yi Zhun; Liu, Jiyong; Ye, Li
Local senolysis in aged mice only partially replicates the benefits of systemic senolysis

老年小鼠的局部衰老仅部分复制了全身性衰老的益处

JOURNAL OF CLINICAL INVESTIGATION
IF13.6
2023-04-1727
OAAI
Farr, Joshua N.; Saul, Dominik; Doolittle, Madison L.; Kaur, Japneet; Rowsey, Jennifer L.; Vos, Stephanie J.; Froemming, Mitchell N.; Lagnado, Anthony B.; Zhu, Yi; Weivoda, Megan; Ikeno, Yuji; Pignolo, Robert J.; Niedernhofer, Laura J.; Robbins, Paul D.; Jurk, Diana; Passos, Joao F.; LeBrasseur, Nathan K.; Tchkonia, Tamara; Kirkland, James L.; Monroe, David G.; Khosla, Sundeep
Rejuvenation of the aged brain immune cell landscape in mice through p16-positive senescent cell clearance

通过p16-positive的衰老细胞清除使小鼠的衰老脑免疫细胞景观恢复活力

NATURE COMMUNICATIONS
IF15.7
2022-09-2748
OAAI
Zhang, Xu; Pearsall, Vesselina M.; Carver, Chase M.; Atkinson, Elizabeth J.; Clarkson, Benjamin D. S.; Grund, Ethan M.; Baez-Faria, Michelle; Pavelko, Kevin D.; Kachergus, Jennifer M.; White, Thomas A.; Johnson, Renee K.; Malo, Courtney S.; Gonzalez-Suarez, Alan M.; Ayasoufi, Katayoun; Johnson, Kurt O.; Tritz, Zachariah P.; Fain, Cori E.; Khadka, Roman H.; Ogrodnik, Mikolaj; Jurk, Diana; Zhu, Yi; Tchkonia, Tamara; Revzin, Alexander; Kirkland, James L.; Johnson, Aaron J.; Howe, Charles L.; Thompson, E. Aubrey; LeBrasseur, Nathan K.; Schafer, Marissa J.
Orally-active, clinically-translatable senolytics restore a-Klotho in mice and humans
EBIOMEDICINE
IF10.8
2022-03-0143
OAAI
Zhu, Yi; Prata, Larissa G. P. Langhi; Gerdes, Erin O. Wissler; Netto, Jair Machado Espindola; Pirtskhalava, Tamar; Giorgadze, Nino; Tripathi, Utkarsh; Inman, Christina L.; Johnson, Kurt O.; Xue, Ailing; Palmer, Allyson K.; Chen, Tingjun; Schaefer, Kalli; Justice, Jamie N.; Nambiar, Anoop M.; Musi, Nicolas; Kritchevsky, Stephen B.; Chen, Jun; Khosla, Sundeep; Jurk, Diana; Schafer, Marissa J.; Tchkonia, Tamar; Kirkland, James L.
Selective Vulnerability of Senescent Glioblastoma Cells to BCL-XL Inhibition
MOLECULAR CANCER RESEARCH
IF4.7
2022-02-2133
OAAI
Rahman, Masum; Olson, Ian; Mansour, Moustafa; Carlstrom, Lucas P.; Sutiwisesak, Rujapope; Saber, Rehan; Rajani, Karishma; Warrington, Arthur E.; Howard, Adam; Schroeder, Mark; Chen, Sisi; Decker, Paul A.; Sananikone, Eliot F.; Zhu, Yi; Tchkonia, Tamar; Parney, Ian F.; Burma, Sandeep; Brown, Desmond; Rodriguez, Moses; Sarkaria, Jann N.; Kirkland, James L.; Burns, Terry C.
Fisetin for COVID-19 in skilled nursing facilities: Senolytic trials in the COVID era

非瑟汀在专业护理机构中的新型冠状病毒肺炎: COVID时代的抗衰老试验

JOURNAL OF THE AMERICAN GERIATRICS SOCIETY
IF4.5
2021-08-2037
OA
Verdoorn, Brandon P.; Evans, Tamara K.; Hanson, Gregory J.; Zhu, Yi; Langhi Prata, Larissa G. P.; Pignolo, Robert J.; Atkinson, Elizabeth J.; Wissler-Gerdes, Erin O.; Kuchel, George A.; Mannick, Joan B.; Kritchevsky, Stephen B.; Khosla, Sundeep; Rizza, Stacey A.; Walston, Jeremy D.; Musi, Nicolas; Lipsitz, Lewis A.; Kiel, Douglas P.; Yung, Raymond; LeBrasseur, Nathan K.; Singh, Ravinder J.; McCarthy, Teresa; Puskarich, Michael A.; Niedernhofer, Laura J.; Robbins, Paul D.; Sorenson, Matthew; Tchkonia, Tamara; Kirkland, James L.

研究方向

GABAA受体功能在神经元兴奋性调节中的作用炎症性疼痛机制
J
James L. Kirkland
H 指数:111论文数:504被引数:6.0万
T
Tamar Tchkonia
H 指数:94论文数:344被引数:4.9万
T
Tamar Pirtskhalava
H 指数:36论文数:98被引数:1.8万
N
Nathan K. LeBrasseur
H 指数:78论文数:324被引数:3.4万
P
Paul D. Robbins
H 指数:123论文数:737被引数:7.3万
L
Laura J. Niedernhofer
H 指数:80论文数:309被引数:3.0万
N
Nino Giorgadze
H 指数:26论文数:72被引数:1.2万
K
Kurt O. Johnson
H 指数:13论文数:19被引数:7,391
L
Larissa Prata
H 指数:20论文数:38被引数:8,046
D
Diana Jurk
H 指数:48论文数:98被引数:2.1万