Marcelo Rubinstein - Publications, H-index & Citations

Marcelo Rubinstein

instituto de investigaciones en ingeniería genética y biología molecular

59H指数

217论文数

1.2W被引数

收录论文 75

发表时间

Highly Conserved STAT3 Motifs Present in the Neuronal Pomc Enhancer nPE1 are Critical for Maximal Hypothalamic Pomc Expression 高度保守的STAT3基序存在于神经元POMC增强子nPE1中，对最大化的下丘脑POMC表达至关重要。

Molecular Neurobiology

IF4.3

2025-11-15

PREAI

Clara E. Hael; Malcolm J. Low; Lucía F. Franchini; Marcelo Rubinstein

The Human Accelerated Region HAR202 Controls NPAS3 Expression in the Developing Forebrain Displaying Differential Enhancer Activity Between Modern and Archaic Human Sequences

MOLECULAR BIOLOGY AND EVOLUTION

IF5.3

2024-09-07

OAAI

Caporale, Alfredo Leandro; Cinalli, Alejandro R.; Rubinstein, Marcelo; Franchini, Lucia F.

The homeodomain transcription factor Six3 regulates hypothalamic Pomc expression and its absence from POMC neurons induces hyperphagia and mild obesity in male mice

MOLECULAR METABOLISM

IF6.6

2024-09-01

OAAI

Yu, Hui; Chiang, Angelika; Rubinstein, Marcelo; Low, Malcolm J.

Accelerated evolution in the human lineage led to gain and loss of transcriptional enhancers in the RBFOX1 locus

SCIENCE ADVANCES

IF12.5

2024-06-28

OAAI

Berasain, Lara; Beati, Paula; Trigila, Anabella P.; Rubinstein, Marcelo; Franchini, Lucia F.

A mammalian tripartite enhancer cluster controls hypothalamic Pomc expression, food intake, and body weight

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2024-04-23

PREAI

Rojo, Daniela; Hael, Clara E.; Soria, Agustina; de Souza, Flavio S. J.; Low, Malcolm J.; Franchini, Lucia F.; Rubinstein, Marcelo

Dopamine D2 receptors in WFS1-neurons regulate food-seeking and avoidance behaviors

PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

IF3.9

2024-02-01

OAAI

Castell, Laia; Le Gall, Valentine; Cutando, Laura; Petit, Chole P.; Puighermanal, Emma; Makrini-Maleville, Leila; Kim, Ha -Rang; Jercog, Daniel; Tarot, Pauline; Tassou, Adrien; Harrus, Anne-Gabrielle; Rubinstein, Marcelo; Rivat, Cyril; Besnard, Antoine; Trifilieff, Pierre; Gangarossa, Giuseppe; Janak, Patricia H.; Herry, Cyril; Valjent, Emmanuel

Accelerated Evolution Analysis Uncovers PKNOX2 as a Key Transcription Factor in the Mammalian Cochlea

MOLECULAR BIOLOGY AND EVOLUTION

IF5.3

2023-05-29

OAAI

Trigila, Anabella P.; Castagna, Valeria C.; Berasain, Lara; Montini, Dante; Rubinstein, Marcelo; Gomez-Casati, Maria Eugenia; Franchini, Lucia F.

Identification of neuronal enhancers of the proopiomelanocortin gene by transgenic mouse analysis and phylogenetic footprinting

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-27

OAAI

de Souza, FSJ; Santangelo, AM; Bumaschny, V; Avale, ME; Smart, JL; Low, MJ; Rubinstein, M

Functional and pharmacological role of the dopamine D4 receptor and its polymorphic variants 多巴胺D4受体及其多态性变体的功能和药理作用

FRONTIERS IN ENDOCRINOLOGY

IF4.6

2022-09-30

OAAI

Ferre, Sergi; Belcher, Annabelle M.; Bonaventura, Jordi; Quiroz, Cesar; Sanchez-Soto, Marta; Casado-Anguera, Veronica; Cai, Ning-Sheng; Moreno, Estefania; Boateng, Comfort A.; Keck, Thomas M.; Floran, Benjamin; Earley, Christopher J.; Ciruela, Francisco; Casado, Vicent; Rubinstein, Marcelo; Volkow, Nora D.

Dopamine D2Rs coordinate cue-evoked changes in striatal acetylcholine levels

ELIFE

IF0

2022-07-20

OAAI

Martyniuk, Kelly M.; Torres-Herraez, Arturo; Lowes, Daniel C.; Rubinstein, Marcelo; Labouesse, Marie A.; Kellendonk, Christoph

Developmental single-cell transcriptomics of hypothalamic POMC neurons reveal the genetic trajectories of multiple neuropeptidergic phenotypes

ELIFE

IF0

2022-01-19

OAAI

Yu, Hui; Rubinstein, Marcelo; Low, Malcolm J.

Heteromerization between α2A adrenoceptors and different polymorphic variants of the dopamine D4 receptor determines pharmacological and functional differences. Implications for impulsive-control disorders Α2a肾上腺素受体与多巴胺D4受体的不同多态性变体之间的杂聚决定了药理和功能差异。对冲动控制障碍的影响

PHARMACOLOGICAL RESEARCH

IF10.5

2021-08-01

OAAI

Casado-Anguera, Veronica; Moreno, Estefania; Sanchez-Soto, Marta; Cai, Ning Sheng; Bonaventura, Jordi; Homar-Ruano, Patricia; Rubinstein, Marcelo; Cortes, Antoni; Canela, Enric, I; Ferre, Sergi; Casado, Vicent

Mouse models for V103I and I251L gain of function variants of the human MC4R display decreased adiposity but are not protected against a hypercaloric diet

MOLECULAR METABOLISM

IF6.6

2020-12-01

OAAI

Rojo, Daniela; McCarthy, Clara; Raingo, Jesica; Rubinstein, Marcelo

Functional redundancy and compensation: Deletion of multiple murineCrispgenes reveals their essential role for male fertility

FASEB JOURNAL

IF4.2

2020-10-10

PREAI

Curci, L.; Brukman, N. G.; Weigel Munoz, M.; Rojo, D.; Carvajal, G.; Sulzyk, V.; Gonzalez, S. N.; Rubinstein, M.; Da Ros, V. G.; Cuasnicu, P. S.

Hypothalamic Pomc expression restricted to GABAergic neurons suppresses Npy overexpression and restores food intake in obese mice

MOLECULAR METABOLISM

IF6.6

2020-07-01

OAAI

Trotta, Milagros; Bello, Estefania Pilar; Alsina, Ramiro; Tavella, Maria Belen; Ferran, Jose Luis; Rubinstein, Marcelo; Bumaschny, Viviana Florencia

Functional and molecular heterogeneity of D2R neurons along dorsal ventral axis in the striatum

NATURE COMMUNICATIONS

IF15.7

2020-04-23

OAAI

Puighermanal, Emma; Castell, Laia; Esteve-Codina, Anna; Melser, Su; Kaganovsky, Konstantin; Zussy, Charleine; Boubaker-Vitre, Jihane; Gut, Marta; Rialle, Stephanie; Kellendonk, Christoph; Sanz, Elisenda; Quintana, Albert; Marsicano, Giovanni; Martin, Miquel; Rubinstein, Marcelo; Girault, Jean-Antoine; Ding, Jun B.; Valjent, Emmanuel

The transcriptional regulator PRDM12 is critical for Pomc expression in the mouse hypothalamus and controlling food intake, adiposity, and body weight

MOLECULAR METABOLISM

IF6.6

2020-04-01

OAAI

Hael, Clara E.; Rojo, Daniela; Orquera, Daniela P.; Low, Malcolm J.; Rubinstein, Marcelo

Expression of a hypomorphic Pomc allele alters leptin dynamics during late pregnancy

JOURNAL OF ENDOCRINOLOGY

IF3.9

2020-04-01

OAAI

Yu, Hui; Thompson, Zoe; Kiran, Sylee; Jones, Graham L.; Mundada, Lakshmi; Surbhi; Rubinstein, Marcelo; Low, Malcolm J.

A Mechanism Linking Two Known Vulnerability Factors for Alcohol Abuse: Heightened Alcohol Stimulation and Low Striatal Dopamine D2 Receptors 将两个已知的酒精滥用脆弱性因素联系起来的机制: 酒精刺激增强和纹状体多巴胺D2受体低

CELL REPORTS

IF6.9

2019-10-01

OAAI

Bocarsly, Miriam E.; da Silva e Silva, Daniel; Kolb, Vanessa; Luderman, Kathryn D.; Shashikiran, Sannidhi; Rubinstein, Marcelo; Sibley, David R.; Dobbs, Lauren K.; Alvarez, Veronica A.

RELEVANCE OF CYSTEIN-RICH SECRETORY PROTEINS FOR FERTILIZATION, FERTILITY AND EARLY EMBRYO DEVELOPMENT

PLACENTA

IF2.5

2019-08-01

PREAI

Weigel Munoz, Mariana; Curci, Ludmila; Brukman, Nicolas; Rojo, Daniela; Rubinstein, Marcelo; Da Ros, Vanina; Cuasnicu, Patricia

研究方向