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M

Maria Tsoli

children's cancer institute
H指数:27
被引数:3,603

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Precision-guided therapy in H3K27-altered diffuse midline glioma

H3K27-改变的弥漫性中线胶质瘤中的精准导向疗法

Nature Communications
IF15.7
2026-05-190
OAAI
Campbell J. L. McKay; Chelsea Mayoh; Phoebe Power; Sophie Jessop; Shampavi Sriharan; Jordan Staunton; Sarah Trinder; Nataliya Zhukova; Cristina Mignone; Dinisha Govender; Frank Alvaro; Peter Downie; Jordan R. Hansford; Tim Hassall; Santosh Valvi; Marion K. Mateos; Paulette Barahona; Andrew J. Gifford; Gabor Tax; Maria Tsoli; Emmy M. Dolman; Marie Wong; Mark Cowley; Glenn M. Marshall; Toby N. Trahair; Paul G. Ekert; Michelle Haber; Vanessa Tyrell; Loretta M. S. Lau; Neevika Manoharan; David S. Ziegler; Dong-Anh Khuong-Quang
Combined inhibition of FACT and BET disrupts transcription to suppress tumor growth in mouse models of diffuse midline glioma

联合抑制FACT和BET破坏转录以抑制弥漫性中线胶质瘤小鼠模型的肿瘤生长

Science Translational Medicine
IF14.6
2026-01-140
PRE
Holliday, Holly; Khan, Aaminah; Ehteda, Anahid; Nguyen, Hieu; Ross, Samuel E.; Jayatilleke, Nisitha; Gopalakrishnan, Anjana; Wang, Eyden; Sanguino, Yolanda Colino; Kavanagh, Daisy; Guo, Xinyi; Liu, Jie; Lawrence, David; Sun, Claire X.; Lehmann, Rebecca; Ip, Chi Kin; Lee, Alvin; Rangel-Sanchez, Laura; Li, Wenyan; Salomon, Robert; Firestein, Ron; Weatheritt, Robert J.; Valdes-Mora, Fatima; Dinger, Marcel E.; Phoenix, Timothy N.; Mayoh, Chelsea; Rayner, Benjamin S.; Tsoli, Maria; Ziegler, David S.
The development of ACT001 with Mcl-1 inhibitors as a novel combination therapy for the treatment of paediatric diffuse midline glioma

ACT001与Mcl-1抑制剂联合开发作为一种新型联合疗法，用于治疗儿童弥漫性中线胶质瘤

NEURO-ONCOLOGY
IF13.4
2025-11-010
OAAI
Lawrence, David; Upton, Dannielle; Tax, Gabor; Holliday, Holly; Ung, Caitlin; Gopalakrishnan, Anjana; Liu, Jie; Dolman, M. Emmy M.; Mao, Jie; Sivanathan, Acadia; Cai, Dongpo Doug; Su, Steven Yung-Chang; Rayner, Benjamin Rayner; Tsoli, Maria; Ziegler, David S.
CHROMATIN REMODELING WITH COMBINED FACT AND BET INHIBITION DISRUPTS ONCOGENIC TRANSCRIPTION IN DIFFUSE MIDLINE GLIOMA

联合FACT和BET抑制的染色质重塑破坏弥漫性中线胶质瘤中的致癌转录

NEURO-ONCOLOGY
IF13.4
2025-11-010
OAAI
Holliday, Holly; Khan, Aaminah; Ehteda, Anahid; Nguyen, Hieu; Ross, Samuel; Jayatilleke, Nisitha; Gopalakrishnan, Anjana; Wang, Eyden; Guo, Xinyi; Sanguino, Yolanda Colino; Kavanagh, Daisy; Liu, Jie; Lawrence, David; Sun, Claire; Lehmann, Rebecca; Ip, Chi Kin; Lee, Alvin; Li, Wenyan; Salomon, Robert; Firestein, Ron; Weatheritt, Robert; Valdes-Mora, Fatima; Dinger, Marcel; Phoenix, Timothy; Mayoh, Chelsea; Rayner, Benjamin; Tsoli, Maria; Ziegler, David
Combination of ALK2 and cholesterol targeting agents exploits linked genetic and metabolic dependencies in diffuse midline glioma

ALK2与胆固醇靶向剂的组合利用弥漫性中线胶质瘤中相互关联的遗传和代谢依赖性

NEURO-ONCOLOGY
IF13.4
2025-11-010
OAAI
Rogers, Rebecca; Grabovska, Yura; Mackay, Alan; Carvalho, Diana; Dobinson, Claire; Pereira, Rita; Burford, Anna; Bevington, Laura; Molinari, Valeria; Song, Jiin; Tari, Haider; Ruddle, Ruth; Nkrumah, Josephine; Sejdiu, Drenusha; Chew, Nicole; Tsui, Vanessa; Sun, Claire; Khan, Aaminah; Pericoli, Giulia; Vinci, Mara; Fortin, Jerome; Sampson, Peter; Tsoli, Maria; Zeigler, David; Firestein, Ron; Jones, Chris
Germline analysis of an international cohort of pediatric diffuse midline glioma patients

对国际队列儿童弥漫性中线胶质瘤患者的生殖系分析

NEURO-ONCOLOGY
IF13.4
2025-03-120
PRE
Marion K Mateos; Pamela Ajuyah; Noemi Fuentes-Bolanos; Sam El-Kamand; Paulette Barahona; Ann-Kristin Altekoester; Chelsea Mayoh; Holly Holliday; Jie Liu; Louise Cui; Elke Pfaff; Alan Mackay; Adam C Resnick; Mark Pinese; Loretta M S Lau; Dong-Anh Khuong-Quang; Kimberly Dias; Catherine Goudie; Alison Salkeld; Jo Lynne Rokita; David T W Jones; Nikoleta Juretic; Elisha Hayden; Stefan M Pfister; Christof M Kramm; Mirjam Blattner-Johnson; Nada Jabado; Maria Tsoli; Orazio Vittorio; Sabine Mueller; Yiran Guo; Katherine Tucker; Sebastian M Waszak; Sebastien Perreault; Chris Jones; Marie Wong-Erasmus; Mark J Cowley; David S Ziegler
High-throughput in vitro drug screening and in vivo studies identify fenretinide as a brain-penetrant DMG therapeutic

高通量体外药物筛选和体内研究将fenretinide确定为一种能够穿透血脑屏障的DMG治疗药物。

NEURO-ONCOLOGY
IF13.4
2025-02-120
PRE
Upton, Dannielle H.; Liu, Jie; George, Sandra M.; Valvi, Santosh; Ung, Caitlin; Rayner, Benjamin S.; Gopalakrishnan, Anjana; Pandher, Ruby; Khan, Aaminah; Venkat, Pooja; Mayoh, Chelsea; Holliday, Holly; Yeung, Nicole; Nguyen, Hieu; Franshaw, Laura; Ehteda, Anahid; Shen, Han; Farruggia, Giovanna; Orienti, Isabella; Reynolds, C. Patrick; Tsoli, Maria; Ziegler, David S.
PEDIATRIC PATIENTS WITH DIFFUSE MIDLINE GLIOMA DEMONSTRATE AN UNEXPECTED PREVALENCE OF GERMLINE VARIANTS IN HOMOLOGOUS RECOMBINATION GENES

弥漫性中线胶质瘤的儿科患者在同源重组基因中表现出意想不到的种系变异患病率

NEURO-ONCOLOGY
IF13.4
2024-06-180
OAAI
Mateos, Marion K.; Ajuyah, Pamela; Fuentes-Bolanos, Noemi; El Kamand, Sam; Barahona, Paulette; Altekoester, Ann; Mayoh, Chelsea; Holiday, Holly; Liu, Jie; Cui, Louise; Pfaff, Elke; Mackay, Alan; Resnick, Adam; Pinese, Mark; Lau, Loretta M. S.; Khuong-Quang, Dong-Anh; Dias, Kimberly; Goudie, Catherine; Salkeld, Alison; Rokita, Jo Lynne; Jones, David T. W.; Juretic, Nikoleta; Hayden, Elisha; Pfister, Stefan M.; Kramm, Christof M.; Blattner-Johnson, Mirjam; Jabado, Nada; Tsoli, Maria; Vittorio, Orazio; Mueller, Sabine; Guo, Yiran; Tucker, Katherine; Waszak, Sebastian M.; Perreault, Sebastien; Jones, Chris; Wong-Erasmus, Marie; Cowley, Mark J.; Ziegler, David S.
PRECISION GUIDED THERAPY PROVIDES CLINICAL BENEFIT IN H3K27-ALTERED DIFFUSE MIDLINE GLIOMA
NEURO-ONCOLOGY
IF13.4
2024-06-180
OAAI
McKay, Campbell; Power, Phoebe; Staunton, Jordan; Sriharan, Shampavi; Jessop, Sophie; Zhukova, Nataliya; Trinder, Sarah; Govender, Dinisha; Barahona, Paulette; Gifford, Andrew J.; Mignone, Cristina; Xie, Angela; Tax, Gabor; Tsoli, Maria; Dolman, Emmy; Mayoh, Chelsea; Wong, Marie; Cowley, Mark; Marshall, Glenn; Trahair, Toby; Lock, Richard B.; Ekert, Paul; Haber, Michelle; Tyrell, Vanessa; Lau, Loretta; Manoharan, Neevika; Ziegler, David S.; Khuong-Quang, Dong-Anh
A comprehensive approach: Copper chelation therapy modulates epigenetic, kinase signaling and metabolic pathways in diffuse midline gliomas (DMG)
CANCER RESEARCH
IF16.6
2024-03-220
PRE
Michniewicz, Filip; Cazzoli, Riccardo; Bell, Jessica; Saletta, Federica; Poursani, Ensieh; Rouaen, Jourdin R.; Shai-Hee, Tyler; Vu Pham; Jue, Toni Rose; Biery, Matthew; Bramberger, Liesl; Lim, Terry; Khan, Aaminah; Giorgi, Federico M.; Mercatelli, Daniele; Mayoh, Chelsea; Cirillo, Giuseppe; Macmillan, Alexander; Whan, Renee; Barlow, Christopher T.; Tsoli, Maria; Vitanza, Nicholas; Berry, Scott; Faridi, Pouya; Ziegler, David; Vittorio, Orazio

研究方向

暂未获取到该数据
D
David S. Ziegler
H 指数:45论文数:632被引数:8,494
C
Chelsea Mayoh
H 指数:33论文数:324被引数:3,952
A
Aaminah Khan
H 指数:7论文数:48被引数:405
M
Michelle Haber
H 指数:65论文数:666被引数:1.6万
刘杰 封面图
刘杰
H 指数:20论文数:92被引数:1,522
D
Dannielle Upton
H 指数:9论文数:37被引数:556
A
Anahid Ehteda
H 指数:17论文数:85被引数:973
L
Laura Franshaw
H 指数:5论文数:45被引数:223
M
Mark J. Cowley
H 指数:63论文数:409被引数:1.9万
A
Anjana Gopalakrishnan
H 指数:7论文数:66被引数:269