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M

Michelle Haber

UNSW Sydney
H指数:65
被引数:1.6万

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The PLK4 inhibitor RP-1664 demonstrates potent efficacy in neuroblastoma preclinical models through a dual mechanism of sensitivity

PLK4抑制剂RP-1664通过双重敏感性机制在神经母细胞瘤临床前模型中显示出显著疗效

Nature Communications
IF15.7
2026-06-130
OAAI
Isabel Soria-Bretones; Matias Casás-Selves; Minu Samanta; David Groff; Jayne Murray; Jamie I. Fletcher; Alvin Farrel; Steven Pastor; Khushbu Patel; Elliot Goodfellow; Li Li; Cathy Caron; Ariya Shiwram; Hyeyeon Kim; Danielle Henry; Nancy Laterreur; Julian Bowlan; Kateryna Krytska; Steven B. Neuhauser; Timothy M. Stearns; Jeffrey A. Schubert; Jinhua Wu; Lea F. Surrey; Daniel Martinez; Crystal Mak; Jennifer Brand; Caitlin Wesley; Klaartje Somers; Alejandro Álvarez-Quilón; Frédéric Vallée; Parham Nejad; Joseph D. Schonhoft; Joanna Li; Artur Veloso; Jordan T. F. Young; Marc L. Hyer; Stephen J. Morris; Yael P. Mossé; C. Gary Marshall; Michelle Haber; Michal Zimmermann; John M. Maris
Precision-guided therapy in H3K27-altered diffuse midline glioma

H3K27-改变的弥漫性中线胶质瘤中的精准导向疗法

Nature Communications
IF15.7
2026-05-190
OAAI
Campbell J. L. McKay; Chelsea Mayoh; Phoebe Power; Sophie Jessop; Shampavi Sriharan; Jordan Staunton; Sarah Trinder; Nataliya Zhukova; Cristina Mignone; Dinisha Govender; Frank Alvaro; Peter Downie; Jordan R. Hansford; Tim Hassall; Santosh Valvi; Marion K. Mateos; Paulette Barahona; Andrew J. Gifford; Gabor Tax; Maria Tsoli; Emmy M. Dolman; Marie Wong; Mark Cowley; Glenn M. Marshall; Toby N. Trahair; Paul G. Ekert; Michelle Haber; Vanessa Tyrell; Loretta M. S. Lau; Neevika Manoharan; David S. Ziegler; Dong-Anh Khuong-Quang
Inclusion of JNK-independent drugs within multiagent chemotherapy improves response in relapsed high-risk neuroblastoma

在多药联合化疗中加入JNK非依赖性药物可改善复发高风险神经母细胞瘤的治疗反应

SCIENCE ADVANCES
IF12.5
2025-11-280
PRE
Han, Jeremy Z. R.; Phimmachanh, Monica; Hastings, Jordan F.; Leong, King Ho; Ng, Boaz H.; Ni, Jenny; Fontaine-Titley, Angela; Cadell, Antonia L.; O'Donnell, Yolande Ei; Clearwater, Misaki; Kamili, Alvin; Haber, Michelle; Norris, Murray; Timpson, Paul; Trahair, Toby N.; Fletcher, Jamie I.; Fey, Dirk; Kolch, Walter; Latham, Sharissa L.; Croucher, David R.
P-glycoprotein as a chemotherapy resistance mechanism and biomarker of poor response in high-risk neuroblastoma
EJC Paediatric Oncology
IF0
2025-11-010
OA
Atkinson, Caroline; Kamili, Alvin; Tactacan, Carole M.; Jayatilleke, Nisitha; Rosser, Sebastian P. A.; Saletta, Federica; Gana, Christine C.; Graber, Philipp; Wanninayaka, Amanda; Ignacio, Rosa Mistica C.; Kavallaris, Maria; Gifford, Andrew J.; Lock, Richard B.; Norris, Murray D.; Haber, Michelle; Mayoh, Chelsea; Nath, Christa E.; Trahair, Toby N.; Fletcher, Jamie I.
Polyamine depletion limits progression of acute leukaemia
INTERNATIONAL JOURNAL OF CANCER
IF4.7
2025-02-220
PRE
Gao, Weiman; Karsa, Mawar; Xiao, Lin; Spurling, Dayna; Karsa, Ayu; Ronca, Emma; Bongers, Angelika; Guo, Xinyi; Mayoh, Chelsea; Azfar, Mujahid; Verhelst, Steven H. L.; Tanaka, Katsunori; Cheung, Laurence C.; Kotecha, Rishi S.; Lock, Richard B.; Burns, Mark R.; Vangheluwe, Peter; Norris, Murray D.; Haber, Michelle; Somers, Klaartje
Copper chelation redirects neutrophil function to enhance anti-GD2 antibody therapy in neuroblastoma

铜螯合改变中性粒细胞功能以增强神经母细胞瘤的anti-GD2抗体治疗

NATURE COMMUNICATIONS
IF15.7
2024-12-120
OAAI
Rouaen, Jourdin R. C.; Salerno, Antonietta; Shai-Hee, Tyler; Murray, Jayne E.; Castrogiovanni, Giulia; Mchenry, Charlotte; Jue, Toni Rose; Pham, Vu; Bell, Jessica Lilian; Poursani, Ensieh; Valli, Emanuele; Cazzoli, Riccardo; Damstra, Naomi; Nelson, Delia J.; Stevens, Kofi L. P.; Chee, Jonathan; Slapetova, Iveta; Kasherman, Maria; Whan, Renee; Lin, Francis; Cochran, Blake J.; Tedla, Nicodemus; Veli, Feyza Colakoglu; Yuksel, Aysen; Mayoh, Chelsea; Saletta, Federica; Mercatelli, Daniele; Chtanova, Tatyana; Kulasinghe, Arutha; Catchpoole, Daniel; Cirillo, Giuseppe; Biro, Mate; Lode, Holger N.; Luciani, Fabio; Haber, Michelle; Gray, Juliet C.; Trahair, Toby N.; Vittorio, Orazio
Golgi-localized Ring Finger Protein 121 is necessary for MYCN-driven neuroblastoma tumorigenesis

高尔基体定位的环指蛋白121是MYCN驱动的神经母细胞瘤肿瘤发生所必需的

COMMUNICATIONS BIOLOGY
IF5.1
2024-10-140
OAAI
Cheung, Belamy B.; Mittra, Ritu; Murray, Jayne; Wang, Qian; Seneviratne, Janith A.; Raipuria, Mukesh; Wong, Iris Poh Ling; Restuccia, David; Gifford, Andrew; Salib, Alice; Sutton, Selina; Huang, Libby; Ferdowsi, Parisa Vahidi; Tsang, Joanna; Sekyere, Eric; Mayoh, Chelsea; Luo, Lin; Brown, Darren L.; Stow, Jennifer L.; Zhu, Shizhen; Young, Richard J.; Solomon, Benjamin J.; Chappaz, Stephane; Kile, Benjamin; Kueh, Andrew; Herold, Marco J.; Hilton, Douglas J.; Liu, Tao; Norris, Murray D.; Haber, Michelle; Carter, Daniel R.; Parker, Michael W.; Marshall, Glenn M.
Clinical utility of real-time comprehensive molecular profiling in childhood brain tumors
CANCER RESEARCH
IF16.6
2024-09-050
PRE
Lau, Loretta M. S.; Khuong-Quang, Dong-Anh; Staunton, Jordan; Sanders, Nicholas; Sriharan, Shampavi; Trinder, Sarah; Manoharan, Neevika; Barahona, Paulette; Altekoester, Ann-Kristin; Dias, Kimberley; Rumford, Megan; Sylvester, Dianne; Parhar, Jasmine; Mateos, Marion K.; Wong, Marie; Mayoh, Chelsea; Cowley, Mark J.; Ekert, Paul G.; Haber, Michelle; Tyrrell, Vanessa; Ziegler, David S.
Implementing ultra-sensitive, ctDNA-based liquid biopsy for disease monitoring in paediatric tumours
CANCER RESEARCH
IF16.6
2024-09-050
PRE
Salomon, Robert; Chen, Wenhan; Shale, Charles; Toumari, Mojgan; Lowe, Aileen; Li, Wenyan; Chen, Jingwei; Bazaz, Sajad Razavi; Barahona, Paulette; Cui, Louise; Mayoh, Chelsea; El-Kamand, Sam; Tryell, Vanessa; Wong-Erasmus, Marie; Lau, Loretta M. S.; Bolanos, Noemi Fuentes; Cuppen, Edwin; Dong Anh Khuong Quang; Staunton, Jordan; Mateos, Marion K.; Trahair, Toby; Haber, Michelle; Ziegler, David S.; Ekert, Paul G.; Priestley, Peter; Cowley, Mark J.
The transcriptional co-repressor Runx1t1 is essential for MYCN-driven neuroblastoma tumorigenesis

转录共阻遏物Runx1t1对于MYCN驱动的神经母细胞瘤肿瘤发生至关重要

NATURE COMMUNICATIONS
IF15.7
2024-07-111
OAAI
Murray, Jayne E.; Valli, Emanuele; Milazzo, Giorgio; Mayoh, Chelsea; Gifford, Andrew J.; Fletcher, Jamie I.; Xue, Chengyuan; Jayatilleke, Nisitha; Salehzadeh, Firoozeh; Gamble, Laura D.; Rouaen, Jourdin R. C.; Carter, Daniel R.; Forgham, Helen; Sekyere, Eric O.; Keating, Joanna; Eden, Georgina; Allan, Sophie; Alfred, Stephanie; Kusuma, Frances K.; Clark, Ashleigh; Webber, Hannah; Russell, Amanda J.; de Weck, Antoine; Kile, Benjamin T.; Santulli, Martina; De Rosa, Piergiuseppe; Fleuren, Emmy D. G.; Gao, Weiman; Wilkinson-White, Lorna; Low, Jason K. K.; Mackay, Joel P.; Marshall, Glenn M.; Hilton, Douglas J.; Giorgi, Federico M.; Koster, Jan; Perini, Giovanni; Haber, Michelle; Norris, Murray D.
Single-base tiled screen unveils design principles of PspCas13b for potent and off-target-free RNA silencing

单碱基平铺屏幕揭示了PspCas13b的设计原理，用于有效和脱靶无RNA沉默

NATURE STRUCTURAL & MOLECULAR BIOLOGY
IF10.1
2024-07-012
OAAI
Hu, Wenxin; Kumar, Amit; Ahmed, Syed Faraz; Qi, Shijiao; Ma, David K. G.; Chen, Honglin; Singh, Gurjeet J.; Casan, Joshua M. L.; Haber, Michelle; Voskoboinik, Ilia; McKay, Matthew R.; Trapani, Joseph A.; Ekert, Paul G.; Fareh, Mohamed
PRECISION GUIDED THERAPY PROVIDES CLINICAL BENEFIT IN H3K27-ALTERED DIFFUSE MIDLINE GLIOMA
NEURO-ONCOLOGY
IF13.4
2024-06-180
OAAI
McKay, Campbell; Power, Phoebe; Staunton, Jordan; Sriharan, Shampavi; Jessop, Sophie; Zhukova, Nataliya; Trinder, Sarah; Govender, Dinisha; Barahona, Paulette; Gifford, Andrew J.; Mignone, Cristina; Xie, Angela; Tax, Gabor; Tsoli, Maria; Dolman, Emmy; Mayoh, Chelsea; Wong, Marie; Cowley, Mark; Marshall, Glenn; Trahair, Toby; Lock, Richard B.; Ekert, Paul; Haber, Michelle; Tyrell, Vanessa; Lau, Loretta; Manoharan, Neevika; Ziegler, David S.; Khuong-Quang, Dong-Anh
Precision-guided treatment in high-risk pediatric cancers
NATURE MEDICINE
IF50
2024-06-067
OAAI
Lau, Loretta M. S.; Khuong-Quang, Dong-Anh; Mayoh, Chelsea; Wong, Marie; Barahona, Paulette; Ajuyah, Pamela; Senapati, Akanksha; Nagabushan, Sumanth; Sherstyuk, Alexandra; Altekoester, Ann-Kristin; Fuentes-Bolanos, Noemi A.; Yeung, Veronica; Sullivan, Ashleigh; Omer, Natacha; Diamond, Yonatan; Jessop, Sophie; Battaglia, Lauren; Zhukova, Nataliya; Cui, Louise; Lin, Angela; Gifford, Andrew J.; Fleuren, Emmy D. G.; Dalla-Pozza, Luciano; Moore, Andrew S.; Khaw, Seong-Lin; Eisenstat, David D.; Gottardo, Nicholas G.; Wood, Paul J.; Tapp, Heather; Alvaro, Frank; McCowage, Geoffrey; Nicholls, Wayne; Hansford, Jordan R.; Manoharan, Neevika; Kotecha, Rishi S.; Mateos, Marion K.; Lock, Richard B.; Tyrrell, Vanessa; Haber, Michelle; Trahair, Toby N.; Cowley, Mark J.; Ekert, Paul G.; Marshall, Glenn M.; Ziegler, David S.

研究方向

暂未获取到该数据
M
Murray D. Norris
H 指数:61论文数:515被引数:1.3万
G
Glenn M. Marshall
H 指数:62论文数:528被引数:1.1万
C
Chelsea Mayoh
H 指数:33论文数:324被引数:4,004
J
Jamie I. Fletcher
H 指数:34论文数:253被引数:9,520
刘涛 封面图
刘涛
H 指数:81论文数:1,061被引数:2.6万
D
David S. Ziegler
H 指数:45论文数:632被引数:8,573
J
Jayne Murray
H 指数:20论文数:168被引数:2,115
A
Andrew J. Gifford
H 指数:32论文数:198被引数:6,478
T
Toby N. Trahair
H 指数:40论文数:270被引数:5,108
B
Belamy B. Cheung
H 指数:34论文数:192被引数:3,586