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R

Roberta Torregrossa

Jagiellonian University
H指数:22
被引数:2,426

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Neuroprotection by post-stroke administration of the slow-releasing hydrogen sulfide (H2S) donor AP39: Long-term functional, MRI, and molecular evidence in a rodent stroke model( vol 1008 , 178331 , 2025)

中风后给予缓释硫化氢（H2S）供体AP39的神经保护作用：在啮齿动物中风模型中的长期功能、MRI和分子证据（卷 1008，178331，2025）

European Journal of Pharmacology
IF4.7
2026-07-150
PRE
Pomierny, Bartosz; Krzyzanowska, Weronika; Skorkowska, Alicja; Jurczyk, Jakub; Przejczowska-Pomierny, Katarzyna; Szafarz, Malgorzata; Marcinkowska, Monika; Guzda, Zuzanna; Rachwal, Patrycja; Kim, Eugene; Mesquita, Michel; Torregrossa, Roberta; Whiteman, Matthew; Pomierny-Chamiolo, Lucyna; Pera, Joanna; Budziszewska, Boguslawa
The Mitochondria-Targeted Hydrogen Sulfide Donor AP39 Reduces Cortical Stroke Volume and Improves Motor Function in a Photothrombotic Stroke Model in Mice in a Sex-Dependent Manner

线粒体靶向硫化氢供体AP39在性别依赖性方式下可减少小鼠光栓性脑卒中模型的皮质卒中体积并改善运动功能

Neuropharmacology
IF4.6
2025-07-260
PRE
Jakub Jurczyk; Zuzanna Guzda; Alicja Skórkowska; Żaneta Broniowska; Małgorzata Piechaczek; Aleksandra Więcek; Emilia Schulze; Angelika Ziaja; Roberta Torregrossa; Matthew Whiteman; Michel Soares Mesquita; Bartosz Pomierny; Lucyna Pomierny-Chamioło
Mitochondria-targeted hydrogen sulfide donor reduces fatty liver and obesity in mice fed a high fat diet by inhibiting de novo lipogenesis and inflammation via mTOR/SREBP-1 and NF-κB signaling pathways

线粒体靶向硫化氢供体通过mTOR/SREBP-1和nf-κb信号通路抑制新生脂肪生成和炎症，减少高脂饮食小鼠脂肪肝和肥胖

PHARMACOLOGICAL RESEARCH
IF10.5
2024-11-010
OAAI
Stachowicz, Aneta; Czepiel, Klaudia; Wisniewska, Anna; Stachyra, Kamila; Ulatowska-Bialas, Magdalena; Kusnierz-Cabala, Beata; Surmiak, Marcin; Majka, Grzegorz; Kus, Katarzyna; Wood, Mark E.; Torregrossa, Roberta; Whiteman, Matthew; Olszanecki, Rafal
Mitochondrial sulfide promotes life span and health span through distinct mechanisms in developing versus adult treated Caenorhabditis elegans
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
2023-07-319
OAAI
Vintila, Adriana Raluca; Slade, Luke; Cooke, Michael; Willis, Craig R. G.; Torregrossa, Roberta; Rahman, Mizanur; Anupom, Taslim; Vanapalli, Siva A.; Gaffney, Christopher J.; Gharahdaghi, Nima; Szabo, Csaba; Szewczyk, Nathaniel J.; Whiteman, Matthew; Etheridge, Timothy
Mitochondrial hydrogen sulfide supplementation improves health in the C. elegans Duchenne muscular dystrophy model
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
2021-02-2433
OAAI
Ellwood, Rebecca A.; Hewitt, Jennifer E.; Torregrossa, Roberta; Philp, Ashleigh M.; Hardee, Justin P.; Hughes, Samantha; van de Klashorst, David; Gharahdaghi, Nima; Anupom, Taslim; Slade, Luke; Deane, Colleen S.; Cooke, Michael; Etheridge, Timothy; Piasecki, Mathew; Antebi, Adam; Lynch, Gordon S.; Philp, Andrew; Vanapalli, Siva A.; Whiteman, Matthew; Szewczyk, Nathaniel J.
Hydrogen sulfide is neuroprotective in Alzheimer's disease by sulfhydrating GSK3β and inhibiting Tau hyperphosphorylation

硫化氢通过使GSK3β 巯基化并抑制Tau过度磷酸化在阿尔茨海默氏病中具有神经保护作用

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
2021-01-11157
OA
Giovinazzo, Daniel; Bursac, Biljana; Sbodio, Juan, I; Nalluru, Sumedha; Vignane, Thibaut; Snowman, Adele M.; Albacarys, Lauren M.; Sedlak, Thomas W.; Torregrossa, Roberta; Whiteman, Matthew; Filipovic, Milos R.; Snyder, Solomon H.; Paul, Bindu D.
Selective Persulfide Detection Reveals Evolutionarily Conserved Antiaging Effects of S-Sulfhydration
CELL METABOLISM
IF30.9
2019-12-01246
OAAI
Zivanovic, Jasmina; Kouroussis, Emilia; Kohl, Joshua B.; Adhikari, Bikash; Bursac, Biljana; Schott-Roux, Sonia; Petrovic, Dunja; Miljkovic, Jan Lj.; Thomas-Lopez, Daniel; Jung, Youngeun; Miler, Marko; Mitchell, Sarah; Milosevic, Verica; Gomes, Jose Eduardo; Benhar, Moran; Gonzales-Zorn, Bruno; Ivanovic-Burmazovic, Ivana; Torregrossa, Roberta; Mitchell, James R.; Whiteman, Matthew; Schwarz, Guenter; Snyder, Solomon H.; Paul, Bindu D.; Carroll, Kate S.; Filipovic, Milos R.

研究方向

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M
Matthew Whiteman
H 指数:71论文数:288被引数:2.0万
M
Mark E. Wood
H 指数:36论文数:226被引数:3,954
M
Miloš R. Filipović
H 指数:44论文数:160被引数:7,849
D
Domokos Gerő
H 指数:29论文数:71被引数:3,147
A
Alicia Waters
H 指数:5论文数:18被引数:345
J
Jan Lj. Miljković
H 指数:19论文数:39被引数:2,375
N
Nathaniel J. Szewczyk
H 指数:39论文数:180被引数:7,664
L
Luke Slade
H 指数:8论文数:13被引数:184
A
Alexis Perry
H 指数:19论文数:71被引数:2,012
T
Timothy Etheridge
H 指数:20论文数:85被引数:2,163