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Effect of lipotoxic hepatocyte-derived extracellular vesicles in pancreas inflammation: essential role of macrophage TLR4 in beta cell functionality 脂毒性肝细胞衍生的细胞外囊泡在胰腺炎症中的作用: 巨噬细胞TLR4在 β 细胞功能中的重要作用 Alen, Rosa; Garcia-Martinez, Irma; Cobo-Vuilleumier, Nadia; Fernandez-Millan, Elisa; Gallardo-Villanueva, Paula; Ferreira, Vitor; Izquierdo, Manuel; Moro, Maria angeles; Lizasoain, Ignacio; Nieto, Natalia; Gauthier, Benoit R.; Valverde, angela M. 分享 收藏
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Health position paper and redox perspectives - Bench to bedside transition for pharmacological regulation of NRF2 in noncommunicable diseases 健康立场文件与氧化还原视角——从实验室到临床：NRF2在非传染性疾病中的药理学调控过渡 Cuadrado, Antonio; Cazalla, Eduardo; Bach, Anders; Bathish, Boushra; Naidu, Sharadha Dayalan; Denicola, Gina M.; Dinkova-Kostova, Albena T.; Fernandez-Gines, Raquel; Grochot-Przeczek, Anna; Hayes, John D.; Kensler, Thomas W.; Leon, Rafael; Liby, Karen T.; Lopez, Manuela G.; Manda, Gina; Shivakumar, Akshatha Kalavathi; Hakomaki, Henriikka; Moerland, Jessica A.; Motohashi, Hozumi; Rojo, Ana I.; Sykiotis, Gerasimos P.; Taguchi, Keiko; Valverde, Angela M.; Yamamoto, Masayuki; Levonen, Anna-Liisa 分享 收藏
Platelet C3G protects from liver fibrosis, while enhancing tumor growth through regulation of the immune response 血小板C3G通过调节免疫反应保护肝脏免受纤维化，同时促进肿瘤生长。 Baquero, Cristina; Iniesta-Gonzalez, Minerva; Palao, Nerea; Fernandez-Infante, Cristina; Cueto-Remacha, Mateo; Mancebo, Jaime; de la Camara-Fuentes, Samuel; Rodrigo-Faus, Maria; Valdecantos, M. Pilar; Valverde, Angela M.; Sequera, Celia; Manzano, Sara; Cuesta, angel M.; Gutierrez-Uzquiza, Alvaro; Bragado, Paloma 分享 收藏
Protein kinase D2 modulates hepatic insulin sensitivity in male mice Rada, Patricia; Carceller-Lopez, Elena; Hitos, Ana B.; Gomez-Santos, Beatriz; Fernandez-Hernandez, Constanza; Rey, Esther; Pose-Utrilla, Julia; Garcia-Monzon, Carmelo; Gonzalez-Rodriguez, Agueda; Sabio, Guadalupe; Garcia, Antonia; Aspichueta, Patricia; Iglesias, Teresa; Valverde, angela M. 分享 收藏
The dual GLP-1/glucagon receptor agonist G49 mimics bariatric surgery effects by inducing metabolic rewiring and inter-organ crosstalk Valdecantos, M. Pilar; Ruiz, Laura; Folgueira, Cintia; Rada, Patricia; Gomez-Santos, Beatriz; Solas, Maite; Hitos, Ana B.; Field, Joss; Francisco, Vera; Escalona-Garrido, Carmen; Zagmutt, Sebastian; Calderon-Dominguez, Maria; Mera, Paula; Garcia-Martinez, Irma; Maymo-Masip, Elsa; Grajales, Diana; Alen, Rosa; Mora, Alfonso; Sainz, Neira; Vides-Urrestarazu, Irene; Vilarrasa, Nuria; Arbones-Mainar, Jose M.; Zaragoza, Carlos; Moreno-Aliaga, Maria J.; Aspichueta, Patricia; Fernandez-Veledo, Sonia; Vendrell, Joan; Serra, Dolors; Herrero, Laura; Schreiber, Renate; Zechner, Rudolf; Sabio, Guadalupe; Hornigold, David; Rondinone, Cristina M.; Jermutus, Lutz; Grimsby, Joseph; Valverde, angela M. 分享 收藏
Astrocytic GLUT1 reduction paradoxically improves central and peripheral glucose homeostasis 星形胶质细胞GLUT1减少矛盾地改善了中枢和外周葡萄糖稳态 Ardanaz, Carlos G.; de la Cruz, Aida; Minhas, Paras S.; Hernandez-Martin, Nira; Pozo, Miguel Angel; Valdecantos, M. Pilar; Valverde, Angela M.; Villa-Valverde, Palmira; Elizalde-Horcada, Marcos; Puerta, Elena; Ramirez, Maria J.; Ortega, Jorge E.; Urbiola, Ainhoa; Ederra, Cristina; Ariz, Mikel; Ortiz-de-Solorzano, Carlos; Fernandez-Irigoyen, Joaquin; Santamaria, Enrique; Karsenty, Gerard; Bruning, Jens C.; Solas, Maite 分享 收藏
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The hepatocyte epidermal growth factor receptor (EGFR) pathway regulates the cellular interactome within the liver fibrotic niche Gonzalez-Sanchez, Ester; Vaquero, Javier; Caballero-Diaz, Daniel; Grzelak, Jan; Fuste, Noel P.; Bertran, Esther; Amengual, Josep; Garcia-Saez, Juan; Martin-Mur, Beatriz; Gut, Marta; Esteve-Codina, Anna; Alay, Ania; Coulouarn, Cedric; Calero-Perez, Silvia; Valdecantos, Pilar; Valverde, Angela M.; Sanchez, Aranzazu; Herrera, Blanca; Fabregat, Isabel 分享 收藏
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GDF15 activates AMPK and inhibits gluconeogenesis and fibrosis in the liver by attenuating the TGF-β1/SMAD3 pathway GDF15通过减弱TGF-β1/SMAD3途径激活AMPK并抑制肝脏糖异生和纤维化 Jurado-Aguilar, Javier; Barroso, Emma; Bernard, Maribel; Zhang, Meijian; Peyman, Mona; Rada, Patricia; Valverde, Angela M.; Wahli, Walter; Palomer, Xavier; Vazquez-Carrera, Manuel 分享 收藏
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Pharmacological and genetic increases in liver NADPH levels ameliorate NASH progression in female mice Rodriguez-Ramiro, Ildefonso; Pastor-Fernandez, Andres; Lopez-Aceituno, Jose Luis; Garcia-Dominguez, Esther; Sierra-Ramirez, Aranzazu; Valverde, Angela M.; Martinez-Pastor, Barbara; Efeyan, Alejo; Gomez-Cabrera, Mari Carmen; Vina, Jose; Fernandez-Marcos, Pablo J. 分享 收藏
Soluble epoxide hydrolase-targeting PROTAC activates AMPK and inhibits endoplasmic reticulum stress 靶向可溶性环氧化物水解酶的PROTAC激活AMPK并抑制内质网应激 Peyman, Mona; Barroso, Emma; Turcu, Andreea L.; Estrany Jr, Francesc; Smith, Daire; Jurado-Aguilar, Javier; Rada, Patricia; Morisseau, Christophe; Hammock, Bruce D.; Valverde, Angela M.; Palomer, Xavier; Galdeano, Carles; Vazquez, Santiago; Vazquez-Carrera, Manuel 分享 收藏
Elafibranor upregulates the EMT-inducer S100A4 via PPARβ/δ Elafibranor通过ppar β/δ 上调EMT诱导剂S100A4 Zhang, Meijian; Barroso, Emma; Ruart, Maria; Pena, Lucia; Peyman, Mona; Aguilar-Recarte, David; Montori-Grau, Marta; Rada, Patricia; Cugat, Clara; Montironi, Carla; Zarei, Mohammad; Jurado-Aguilar, Javier; Camins, Antoni; Balsinde, Jesus; Valverde, Angela M.; Wahli, Walter; Palomer, Xavier; Vazquez-Carrera, Manuel 分享 收藏
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