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J

Jeffrey L. Wrana

University of Toronto

119H指数
505论文数
5.9W被引数
收录论文 162
发表时间
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Long-read RNA sequencing identifies non-coding isoform switching as a regulator of cell fate长读长RNA测序识别非编码异构体切换作为细胞命运的调控因子
errNature Communications
IF15.7
err2026-09-24
err0
errOAAI
errVictoire Fort; Gabriel Khelifi; Ruicen He; Valérie Watters; Melanie Pye; Nobuko Yamanaka; Marina Gertsenstein; Émeline I. J. Lelong; Jérémy Loehr; Victoria Micha; Jean-Philippe Lambert; Yojiro Yamanaka; Jeffrey Wrana; Samer M. I. Hussein
err分享
err收藏
Aneuploidy selects for the acquisition of driver genes in breast cancer非整倍性选择乳腺癌症中驱动基因的获取
errNature
IF48.5
err2026-07-08
err0
PREAI
errKhalid N. Al-Zahrani; Ellen R. Langille; Jocelyn Nurtanto; Andreea Obersterescu; Katie Teng; Christopher Lowden; Julien Dessapt; Cynthia H. Chiu; Lauren V. Caldwell; David P. Cook; Miguel A. Pérez-Castro; Jacob M. Berman; Ricky Tsai; Alexander T. Bahcheli; Geraldine Mbamalu; Shifei Wu; Masahiro Narimatsu; Adele G. Lopes; Iosifina Fotiadou; Kin Chan; Linkang Zhang; K. W. Annie Bang; Michael J. Parsons; Larissa Mourao; E. Idil Temel; Liddy McCulla; Palavalasa Sravya; Li Zhang; Peter Sajjakulnukit; Costas A. Lyssiotis; Alexander D. Borowsky; Colinda L. G. J. Scheele; Daniel R. Wahl; Hartland W. Jackson; Katherine S. Stewart; Elaine Fuchs; Sean E. Egan; Miguel Angel Pujana; Jüri Reimand; Jeffrey L. Wrana; Daniel Schramek
err分享
err收藏
OC43 clinical isolate spike proteins have distinct carbohydrate-binding propertiesOC43临床分离株刺突蛋白具有独特的碳水化合物结合特性
errNature Communications
IF15.7
err2026-05-16
err0
errOAAI
errZaky Hassan; Min Jin; Ying Liu; Zhijie Li; Alan H. M. Wong; Marc Desforges; Adam Forman; Mark Nitz; Tarini Gunawardena; Theo J. Moraes; Masahiro Narimatsu; Jeffrey L. Wrana; Hai Yu; Xi Chen; James M. Rini
err分享
err收藏
Discovery and development of potent and selective dual NUAK/MARK inhibitors as Hippo pathway modulators for the treatment of cancer作为Hippo通路调节剂，用于癌症治疗的强效且选择性的双NUAK/MARK抑制剂的发现与开发
errEuropean Journal of Medicinal Chemistry
IF5.9
err2026-03-31
err0
PREAI
errDavid Smil; Yong Liu; Tao Xin; Taira Kiyota; Ahmed Aman; Julie Grouleff; Laurent Hoffer; Dhananjay C. Joshi; Mohammad R. Inanlou; Siyuan Song; Daniel Y.L. Mao; Abiodun A. Ogunjimi; Victor Pau; Fiona D. Chini; Igor Kurinov; Ying Zhang; Anh Thu Nguyen; Jeffrey L. Wrana; Frank Sicheri; Liliana Attisano
err分享
err收藏
Standardized metrics for assessment and reproducibility of imaging-based spatial transcriptomics datasets基于成像的空间转录组学数据集的评估和可重复性的标准化指标
errNature Biotechnology
IF41.7
err2025-12-03
err0
errOAAI
errJasmine T. Plummer; Felipe Segato Dezem; David P. Cook; Jiwoon Park; Luke Zhang; Yutian Liu; Maycon Marção; Hannah DuBose; Arjumand Wani; Kellie Wise; Michael Roach; Kate Harvey; Taopeng Wang; Kirk B. Jensen; Natalia Morosini; Roberto De Gregorio; Alicia Alonso; Shauna Lee Houlihan; Robert E. Schwartz; Erika Hissong; Catherine Snopkowski; Jeffrey L. Wrana; Natalie Ryan; Lisa M. Butler; George Church; Alexander Swarbrick; Christopher E. Mason; Luciano G. Martelotto
err分享
err收藏
Bacterial ADP-heptose triggers stem cell regeneration in the intestinal epithelium following injury细菌ADP-庚糖在损伤后触发肠道上皮的干细胞再生
errCell Stem Cell
IF20.4
err2025-07-11
err0
PREAI
errShawn Goyal; Cynthia X. Guo; Ojas Singh; Adrienne Ranger; Caitlin F. Harrigan; Justin Meade; Alexander Luchak; Derek K. Tsang; Herbert Y. Gaisano; Nan Gao; Scott A. Yuzwa; Jeffrey L. Wrana; Dana J. Philpott; Scott D. Gray-Owen; Stephen E. Girardin
err分享
err收藏
Modelling the Liver’s Regenerative Capacity across Different Clinical Conditions模拟肝脏在不同临床条件下的再生能力
errJHEP Reports
IF7.5
err2025-05-01
err0
errOAAI
errAnh Thu Nguyen Lefebvre; Soumita Ghosh; Cristina Baciu; Bima J. Hasjim; Sara Naimimohasses; Graziano Oldani; Elisa Pasini; Michael Brudno; Nazia Selzner; Jeffrey Wrana; Mamatha Bhat
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err收藏
Atypical function of a centrosomal module in WNT signalling drives contextual cancer cell motility (vol 10, 2356, 2019)中心体模块在WNT信号通路中的非典型功能驱动背景依赖性癌细胞运动（vol 10, 2356, 2019）
errNATURE COMMUNICATIONS
IF15.7
err2025-02-26
err0
errOAAI
errLuo, Yi; Barrios-Rodiles, Miriam; Gupta, Gagan D.; Zhang, Ying Y.; Ogunjimi, Abiodun A.; Bashkurov, Mikhail; Tkach, Johnny M.; Underhill, Ainsley Q.; Zhang, Liang; Bourmoum, Mohamed; Wrana, Jeffrey L.; Pelletier, Laurence
err分享
err收藏
Small Extracellular Vesicles Promote Axon Outgrowth by Engaging the Wnt-Planar Cell Polarity Pathway小的细胞外囊泡通过参与Wnt平面细胞极性途径促进轴突生长
errCELLS
IF5.2
err2025-01-06
err0
errOAAI
errAhmad, Samar; Christova, Tania; Pye, Melanie; Narimatsu, Masahiro; Song, Siyuan; Wrana, Jeffrey L.; Attisano, Liliana
err分享
err收藏
Chromatin remodelling in damaged intestinal crypts orchestrates redundant TGFβ and Hippo signalling to drive regeneration
errNATURE CELL BIOLOGY
IF19.1
err2024-11-15
err0
PREAI
errFink, Mardi; Njah, Kizito; Patel, Shyam J.; Cook, David P.; Man, Vanessa; Ruso, Francesco; Rajan, Arsheen; Narimatsu, Masahiro; Obersterescu, Andreea; Pye, Melanie J.; Trcka, Daniel; Chan, Kin; Ayyaz, Arshad; Wrana, Jeffrey L.
err分享
err收藏
Integrated single-cell analysis defines the epigenetic basis of castration-resistant prostate luminal cells
errCELL STEM CELL
IF20.4
err2024-08-01
err0
errOAAI
errKirk, Jason S.; Wang, Jie; Long, Mark; Rosario, Spencer; Tracz, Amanda; Ji, Yibing; Kumar, Rahul; Liu, Xiaozhuo; Jamroze, Anmbreen; Singh, Prashant K.; Puzanov, Igor; Chatta, Gurkamal; Cheng, Qing; Huang, Jiaoti; Wrana, Jeffrey L.; Lovell, Jonathan; Yu, Han; Liu, Song; Shen, Michael M.; Liu, Tao; Tang, Dean G.
err分享
err收藏
High-throughput sensitive screening of small molecule modulators of microexon alternative splicing using dual Nano and Firefly luciferase reporters
errNATURE COMMUNICATIONS
IF15.7
err2024-07-27
err0
errOAAI
errBest, Andrew J.; Braunschweig, Ulrich; Wu, Mingkun; Farhangmehr, Shaghayegh; Pasculescu, Adrian; Lim, Justin J.; Comsa, Lim Caden; Jen, Mark; Wang, Jenny; Datti, Alessandro; Wrana, Jeffrey L.; Cordes, Sabine P.; Al-awar, Rima; Han, Hong; Blencowe, Benjamin J.
err分享
err收藏
p53 promotes revival stem cells in the regenerating intestine after severe radiation injuryp53促进严重辐射损伤后再生肠道中的再生干细胞
errNATURE COMMUNICATIONS
IF15.7
err2024-04-08
err6
errOAAI
errMorral, Clara; Ayyaz, Arshad; Kuo, Hsuan-Cheng; Fink, Mardi; Verginadis, Ioannis I.; Daniel, Andrea R.; Burner, Danielle N.; Driver, Lucy M.; Satow, Sloane; Hasapis, Stephanie; Ghinnagow, Reem; Luo, Lixia; Ma, Yan; Attardi, Laura D.; Koumenis, Constantinos; Minn, Andy J.; Wrana, Jeffrey L.; Lee, Chang-Lung; Kirsch, David G.
err分享
err收藏
YAP targetome reveals activation of SPEM in gastric pre-neoplastic progression and regeneration
errCELL REPORTS
IF6.9
err2023-12-01
err2
errOAAI
errLoe, Adrian K. H.; Rao-Bhatia, Abilasha; Wei, Zhao; Kim, Jung-Eun; Guan, Bingxin; Qin, Yan; Hong, Minji; Kwak, Hyo Sang; Liu, Xiaoyu; Zhang, Leyi; Wrana, Jeffrey L.; Guo, Haiyang; Kim, Tae-Hee
err分享
err收藏
In vivo CRISPR screens reveal Serpinb9 and Adam2 as regulators of immune therapy response in lung cancer (vol 14, 3150, 2023)
errNATURE COMMUNICATIONS
IF15.7
err2023-09-05
err0
errOAAI
errDervovic, Dzana; Malik, Ahmad A.; Chen, Edward L. Y.; Narimatsu, Masahiro; Adler, Nina; Afiuni-Zadeh, Somaieh; Krenbek, Dagmar; Martinez, Sebastien; Tsai, Ricky; Boucher, Jonathan; Berman, Jacob M.; Teng, Katie; Ayyaz, Arshad; Lu, Yiqing; Mbamalu, Geraldine; Loganathan, Sampath K.; Lee, Jongbok; Zhang, Li; Guidos, Cynthia; Wrana, Jeffrey; Valipour, Arschang; Roux, Philippe P.; Reimand, Juri; Jackson, Hartland W.; Schramek, Daniel
err分享
err收藏
Adseverin, an actin-binding protein, modulates hypertrophic chondrocyte differentiation and osteoarthritis progression肌动蛋白结合蛋白Adseverin调节肥大软骨细胞分化和骨关节炎进展
errSCIENCE ADVANCES
IF12.5
err2023-08-04
err5
errOAAI
errChan, Byron; Glogauer, Michael; Wang, Yongqiang; Wrana, Jeffrey; Chan, Kin; Beier, Frank; Bali, Supinder; Hinz, Boris; Parreno, Justin; Ashraf, Sajjad; Kandel, Rita
err分享
err收藏
Hgs (Hrs), a FYVE domain protein, is involved in Smad signaling through cooperation with SARA
errMOLECULAR AND CELLULAR BIOLOGY
IF2.7
err2023-03-28
err190
errOAAI
errMiura, S; Takeshita, T; Asao, H; Kimura, Y; Murata, K; Sasaki, Y; Hanai, J; Beppu, H; Tsukazaki, T; Wrana, JL; Miyazono, K; Sugamura, K
err分享
err收藏
GATA- and Smad1-dependent enhancers in the Smad7 gene differentially interpret bone morphogenetic protein concentrations
errMOLECULAR AND CELLULAR BIOLOGY
IF2.7
err2023-03-27
err96
errOAAI
errBenchabane, H; Wrana, JL
err分享
err收藏
Myostatin signals through a transforming growth factor β-like signaling pathway to block adipogenesis
errMOLECULAR AND CELLULAR BIOLOGY
IF2.7
err2023-03-27
err609
errOAAI
errRebbapragada, A; Benchabane, H; Wrana, JL; Celeste, AJ; Attisano, L
err分享
err收藏
Mink1 Regulates β-Catenin-Independent Wnt Signaling via Prickle Phosphorylation
errMOLECULAR AND CELLULAR BIOLOGY
IF2.7
err2023-03-20
err50
errOAAI
errDaulat, Avais M.; Luu, Olivia; Sing, Anson; Zhang, Liang; Wrana, Jeffrey L.; McNeill, Helen; Winklbauer, Rudolf; Angers, Stephane
err分享
err收藏

研究方向

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