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IDHwt glioblastomas can be stratified by their transcriptional response to standard treatment, with implications for targeted therapy IDHwt胶质母细胞瘤可以通过其对标准治疗的转录反应进行分层，对靶向治疗有影响 Tanner, Georgette; Barrow, Rhiannon; Ajaib, Shoaib; Al-Jabri, Muna; Ahmed, Nazia; Pollock, Steven; Finetti, Martina; Rippaus, Nora; Bruns, Alexander F.; Syed, Khaja; Poulter, James A.; Matthews, Laura; Hughes, Thomas; Wilson, Erica; Johnson, Colin; Varn, Frederick S.; Bruning-Richardson, Anke; Hogg, Catherine; Droop, Alastair; Gusnanto, Arief; Care, Matthew A.; Cutillo, Luisa; Westhead, David R.; Short, Susan C.; Jenkinson, Michael D.; Brodbelt, Andrew; Chakrabarty, Aruna; Ismail, Azzam; Verhaak, Roel G. W.; Stead, Lucy F. 分享 收藏
Photoactive imaging and therapy for colorectal cancer using a CEA-Affimer conjugated Foslip nanoparticle 使用CEA-Affimer共轭Foslip纳米颗粒对结直肠癌进行光敏成像和治疗 Khaled, Yazan S.; Khot, M. Ibrahim; Aiyappa-Maudsley, Radhika; Maisey, Thomas; Pramanik, Arindam; Tiernan, Jim; Lintern, Nicole; Al-Enezi, Eiman; Shamsuddin, Shazana H.; Tomlinson, Darren; Coletta, Louise; Millner, Paul A.; Hughes, Thomas A.; Jayne, David G. 分享 收藏
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Affimer Tagged Cubosomes: Targeting of Carcinoembryonic Antigen Expressing Colorectal Cancer Cells Using In Vitro and In Vivo Models Affimer标记的立方体: 使用体外和体内模型靶向表达癌胚抗原的结直肠癌细胞 Pramanik, Arindam; Xu, Zexi; Shamsuddin, Shazana H.; Khaled, Yazan S.; Ingram, Nicola; Maisey, Thomas; Tomlinson, Darren; Coletta, P. Louise; Jayne, David; Hughes, Thomas A.; Tyler, Arwen I. I.; Millner, Paul A. 分享 收藏
Pharmacologic and genetic inhibition of cholesterol esterification enzymes reduces tumour burden: A systematic review and meta-analysis of preclinical models 胆固醇酯化酶的药理学和遗传抑制降低肿瘤负担: 临床前模型的系统评价和荟萃分析 Websdale, Alex; Kiew, Yi; Chalmers, Philip; Chen Xinyu; Cioccoloni, Giorgia; Hughes, Thomas A.; Luo Xinyu; Mwarzi, Rufaro; Poirot, Marc; Roberg-Larsen, Hanne; Wu Ruoying; Xu Mengfan; Zulyniak, Michael A.; Thorne, James L. 分享 收藏
Cholesterol esterification enzymes promote cancer growth and are potential therapeutic targets for repurposed drugs: a systematic review and meta-analysis of pre-clinical evidence Websdale, A.; Chalmers, P.; Chen, X.; Kiew, Y.; Luo, X.; Mwarazi, R.; Wu, R.; Cioccoloni, G.; Roberg-Larsen, H.; Hughes, T. A.; Zulyniak, M. A.; Thorne, J. L. 分享 收藏
Overlap between nutrient metabolism and chemotherapy detoxification in triple negative breast cancer Cioccoloni, G.; Websdale, A.; Soteriou, C.; Lianto, P.; Hutchinson, S. A.; Hughes, T. A.; Vasconcelos, E. J. R.; Forde, N.; Kim, B.; Zulyniak, M. A.; Thorne, J. L. 分享 收藏
Transcriptome profiles of stem-like cells from primary breast cancers allow identification of ITGA7 as a predictive marker of chemotherapy response 来自原发性乳腺癌的干细胞样细胞的转录组谱允许将ITGA7鉴定为化疗反应的预测标志物 Gwili, Noha; Jones, Stacey J.; Al Amri, Waleed; Carr, Ian M.; Harris, Sarah; Hogan, Brian, V; Hughes, William E.; Kim, Baek; Langlands, Fiona E.; Millican-Slater, Rebecca A.; Pramanik, Arindam; Thorne, James L.; Verghese, Eldo T.; Wells, Geoff; Hamza, Mervat; Younis, Layla; El Deeb, Nevine M. F.; Hughes, Thomas A. 分享 收藏
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Liver x receptor alpha drives chemoresistance in response to side-chain hydroxycholesterols in triple negative breast cancer 在三阴性乳腺癌中，肝x受体 α 驱动对侧链羟基胆固醇的化学抗性 Hutchinson, Samantha A.; Websdale, Alex; Cioccoloni, Giorgia; Roberg-Larsen, Hanne; Lianto, Priscilia; Kim, Baek; Rose, Ailsa; Soteriou, Chrysa; Pramanik, Arindam; Wastall, Laura M.; Williams, Bethany J.; Henn, Madeline A.; Chen, Joy J.; Ma, Liqian; Moore, J. Bernadette; Nelson, Erik; Hughes, Thomas A.; Thorne, James L. 分享 收藏
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Cholesterol side-chain hydroxylation is associated with expression of P-glycoprotein and disease-free survival in triple negative breast cancer patients Websdale, A.; Hutchinson, S. A.; Lianto, P.; Roberg-Larsen, H.; Wastall, L. M.; Williams, B.; Rose, A.; Sharma, N.; Hughes, T. A.; Thorne, J. L. 分享 收藏
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