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I

Igor Ruiz de los Mozos

the francis crick institute
H指数:21
被引数:2,063

个人简介

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教育背景

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工作经历

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荣誉奖项

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Phosphorylation of SF3B1 by CDK11 orchestrates spliceosome activation via SNIP1-dependent RES complex recruitment

CDK11介导的SF3B1磷酸化通过SNIP1依赖的RES复合物招募调控剪接体的激活

Nature Communications
IF15.7
2026-03-290
OA
Pavla Gajdušková; Igor Ruiz de Los Mozos; Milan Hluchý; Antonina Myšková; Kateřina Zábrady; Peter Maník; Neda Dragišić; Kateřina Hanáková; David Potěšil; Sara Bologna; Jiří Nováček; Caroline C. Friedel; Konstantinos Tripsianes; Zbyněk Zdráhal; Dalibor Blazek
Meta-unstable mRNAs in activated CD8+ T cells are defined by interlinked AU-rich elements and m6A mRNA methylation

激活的CD8 T细胞中的元不稳定mRNA由相互连接的富含AU的元件和m6A mRNA甲基化定义

Nature Communications
IF15.7
2026-01-220
OAAI
Paulo A. Gameiro; Iosifina P. Foskolou; Yumna A. Butt; Aniek A. M. Martens; Klara Kuret Hodnik; Igor Ruiz de los Mozos; Nordin D. Zandhuis; Žan Hozjan; Veronica M. Kot; Rupert Faraway; Michiel Vermeulen; Monika C. Wolkers; Randall S. Johnson; Jernej Ule
Gut microbiota produces biofilm-associated amyloids with potential for neurodegeneration

肠道菌群产生与生物膜相关的淀粉样蛋白，具有神经变性的潜力

NATURE COMMUNICATIONS
IF15.7
2024-05-164
OAAI
Fernandez-Calvet, Ariadna; Matilla-Cuenca, Leticia; Izco, Maria; Navarro, Susanna; Serrano, Miriam; Ventura, Salvador; Blesa, Javier; Herraiz, Maite; Alkorta-Aranburu, Gorka; Galera, Sergio; Ruiz de los Mozos, Igor; Mansego, Maria Luisa; Toledo-Arana, Alejandro; Alvarez-Erviti, Lydia; Valle, Jaione
IL-6/STAT3 signaling in tumor cells restricts the expression of frameshift-derived neoantigens by SMG1 induction

肿瘤细胞中的IL-6/STAT3信号通路通过诱导SMG1表达，从而抑制移码突变衍生的新抗原的表达。

MOLECULAR CANCER
IF33.9
2022-11-2815
OAAI
Meraviglia-Crivelli, Daniel; Villanueva, Helena; Zheleva, Angelina; Villalba-Esparza, Maria; Moreno, Beatriz; Menon, Ashwathi Puravankara; Calvo, Alfonso; Cebollero, Javier; Barainka, Martin; de los Mozos, Igor Ruiz; Huesa-Berral, Carlos; Pastor, Fernando
CDK11 regulates pre-mRNA splicing by phosphorylation of SF3B1
Nature
IF48.5
2022-09-140
PRE
Milan Hluchý; Pavla Gajdušková; Igor Ruiz de los Mozos; Michal Rájecký; Michael Kluge; Benedict-Tilman Berger; Zuzana Slabá; David Potěšil; Elena Weiß; Jernej Ule; Zbyněk Zdráhal; Stefan Knapp; Kamil Paruch; Caroline C. Friedel; Dalibor Blazek
Sequential inverse dysregulation of the RNA helicases DDX3X and DDX3Y facilitates MYC-driven lymphomagenesis
MOLECULAR CELL
IF16.6
2021-10-0149
OA
Gong, Chun; Krupka, Joanna A.; Gao, Jie; Grigoropoulos, Nicholas F.; Giotopoulos, George; Asby, Ryan; Screen, Michael; Usheva, Zelvera; Cucco, Francesco; Barrans, Sharon; Painter, Daniel; Zaini, Nurmahirah Binte Mohammed; Haupl, Bjoern; Bornelov, Susanne; De Los Mozos, Igor Ruiz; Meng, Wei; Zhou, Peixun; Blain, Alex E.; Forde, Sorcha; Matthews, Jamie; Tan, Michelle Guet Khim; Burke, G. A. Amos; Sze, Siu Kwan; Beer, Philip; Burton, Cathy; Campbell, Peter; Rand, Vikki; Turner, Suzanne D.; Ule, Jernej; Roman, Eve; Tooze, Reuben; Oellerich, Thomas; Huntly, Brian J.; Turner, Martin; Du, Ming-Qing; Samarajiwa, Shamith A.; Hodson, Daniel J.

研究方向

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J
Jernej Ule
H 指数:76论文数:293被引数:2.6万
A
Alejandro Toledo‐Arana
H 指数:35论文数:132被引数:6,320
Í
Íñigo Lasa
H 指数:63论文数:191被引数:1.3万
C
Cristina Solano
H 指数:28论文数:111被引数:5,712
M
Maite Villanueva
H 指数:13论文数:22被引数:1,177
J
Jaione Valle
H 指数:38论文数:63被引数:7,106
V
Víctor Segura
H 指数:43论文数:188被引数:5,426
D
Dalibor Blažek
H 指数:18论文数:31被引数:2,006
M
Marta Vergara-Irigaray
H 指数:12论文数:31被引数:1,710
F
Fernando Pastor
H 指数:27论文数:83被引数:2,811