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J

Jernej Ule

the francis crick institute
H指数:76
被引数:2.6万

个人简介

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教育背景

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工作经历

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荣誉奖项

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Short RNA chaperones promote aggregation-resistant TDP-43 conformers to mitigate neurodegeneration

短链RNA分子伴侣促进抗聚集的TDP-43构象体以减轻神经退行性变化

Science
IF45.8
2026-05-070
PRE
Katie E. Copley; Jocelyn C. Mauna; Helen L. Danielson; Qizan Chen; Busra Ozguney; Marilyn Ngo; Longxin Xie; Ashleigh Smirnov; Matt Davis; Leland Mayne; Miriam Linsenmeier; Jack D. Rubien; Cristian A. Bergmann; Bede Portz; Bo Lim Lee; Hana M. Odeh; Longsheng Lai; Yi-Wei Chang; Martina Hallegger; Jernej Ule; Piera Pasinelli; Yan Poon; Jeetain Mittal; Nicolas L. Fawzi; Ben E. Black; Christopher J. Donnelly; Brigid K. Jensen; James Shorter
Meta-unstable mRNAs in activated CD8+ T cells are defined by interlinked AU-rich elements and m6A mRNA methylation

激活的CD8 T细胞中的元不稳定mRNA由相互连接的富含AU的元件和m6A mRNA甲基化定义

Nature Communications
IF15.7
2026-01-220
OAAI
Paulo A. Gameiro; Iosifina P. Foskolou; Yumna A. Butt; Aniek A. M. Martens; Klara Kuret Hodnik; Igor Ruiz de los Mozos; Nordin D. Zandhuis; Žan Hozjan; Veronica M. Kot; Rupert Faraway; Michiel Vermeulen; Monika C. Wolkers; Randall S. Johnson; Jernej Ule
Collective homeostasis of condensation-prone proteins via their mRNAs

凝聚倾向蛋白通过其mRNA实现的集体稳态

Nature
IF48.5
2025-09-240
OAAI
Rupert Faraway; Neve Costello Heaven; Holly Digby; Klara Kuret Hodnik; Jure Rebselj; Oscar G. Wilkins; Anob M. Chakrabarti; Ira A. Iosub; Neža Vadnjal; Rhys Dore; Lea Knez; Stefan L. Ameres; Clemens Plaschka; Jernej Ule
NEAT1 modulates the TIRR/53BP1 complex to maintain genome integrity

NEAT1调节TIRR/53BP1复合物以维持基因组完整性

NATURE COMMUNICATIONS
IF15.7
2024-09-300
OAAI
Kilgas, Susan; Syed, Aleem; Toolan-Kerr, Patrick; Swift, Michelle L.; Roychoudhury, Shrabasti; Sarkar, Aniruddha; Wilkins, Sarah; Quigley, Mikayla; Poetsch, Anna R.; Botuyan, Maria Victoria; Cui, Gaofeng; Mer, Georges; Ule, Jernej; Drane, Pascal; Chowdhury, Dipanjan
Mis-spliced transcripts generate de novo proteins in TDP-43-related ALS/FTD

错误剪接的转录本在TDP-43-related ALS/FTD中产生新生蛋白

SCIENCE TRANSLATIONAL MEDICINE
IF14.6
2024-02-1420
OA
Seddighi, Sahba; Qi, Yue A.; Brown, Anna-Leigh; Wilkins, Oscar G.; Bereda, Colleen; Belair, Cedric; Zhang, Yong-Jie; Prudencio, Mercedes; Keuss, Matthew J.; Khandeshi, Aditya; Pickles, Sarah; Kargbo-Hill, Sarah E.; Hawrot, James; Ramos, Daniel M.; Yuan, Hebao; Roberts, Jessica; Sacramento, Erika Kelmer; Shah, Syed I.; Nalls, Mike A.; Colon-Mercado, Jennifer M.; Reyes, Joel F.; Ryan, Veronica H.; Nelson, Matthew P.; Cook, Casey N.; Li, Ziyi; Screven, Laurel; Kwan, Justin Y.; Mehta, Puja R.; Zanovello, Matteo; Hallegger, Martina; Shantaraman, Anantharaman; Ping, Lingyan; Koike, Yuka; Oskarsson, Bjorn; Staff, Nathan P.; Duong, Duc M.; Ahmed, Aisha; Secrier, Maria; Ule, Jernej; Jacobson, Steven; Reich, Daniel S.; Rohrer, Jonathan D.; Malaspina, Andrea; Dickson, Dennis W.; Glass, Jonathan D.; Ori, Alessandro; Seyfried, Nicholas T.; Maragkakis, Manolis; Petrucelli, Leonard; Fratta, Pietro; Ward, Michael E.
The paralogues MAGOH and MAGOHB are oncogenic factors in high-grade gliomas and safeguard the splicing of cell division and cell cycle genes

旁系同源物MAGOH和MAGOHB是高级别神经胶质瘤的致癌因素，并保护细胞分裂和细胞周期基因的剪接

RNA BIOLOGY
IF3.4
2023-06-093
OAAI
Barreiro, Rodrigo A. S.; Guardia, Gabriela D. A.; Meliso, Fabiana M.; Lei, Xiufen; Li, Wei-Qing; Savio, Andre; Fellermeyer, Martin; Conceicao, Helena B.; Mercuri, Rafael L. V.; Landry, Tesha; Qiao, Mei; Blazquez, Lorea; Ule, Jernej; Penalva, Luiz O. F.; Galante, Pedro A. F.
HNRNPH1 regulates the neuroprotective cold-shock protein RBM3 expression through poison exon exclusion

HNRNPH1通过毒物外显子排斥调节神经保护性冷休克蛋白RBM3的表达

EMBO JOURNAL
IF8.3
2023-05-307
OA
Lin, Julie Qiaojin; Khuperkar, Deepak; Pavlou, Sofia; Makarchuk, Stanislaw; Patikas, Nikolaos; Lee, Flora C. Y.; Zbiegly, Julia M.; Kang, Jianning; Field, Sarah F.; Bailey, David M. D.; Freeman, Joshua L.; Ule, Jernej; Metzakopian, Emmanouil; Ruepp, Marc-David; Mallucci, Giovanna R.

研究方向

暂未获取到该数据
N
Nicholas M. Luscombe
H 指数:73论文数:251被引数:2.8万
T
Tomaž Curk
H 指数:43论文数:109被引数:1.1万
J
Julian König
H 指数:34论文数:105被引数:5,945
C
Christopher R. Sibley
H 指数:24论文数:50被引数:2,751
K
Kathi Zarnack
H 指数:37论文数:151被引数:5,909
I
Igor Ruiz de los Mozos
H 指数:21论文数:66被引数:2,057
N
Nejc Haberman
H 指数:16论文数:42被引数:1,563
J
Jan Attig
H 指数:24论文数:48被引数:3,491
A
Anob M. Chakrabarti
H 指数:13论文数:54被引数:1,308
R
Rupert Faraway
H 指数:10论文数:36被引数:1,207