David N. Brindley - Publications, H-index & Citations

David N. Brindley

cancer research institute of northern alberta

70H指数

347论文数

1.6W被引数

收录论文 96

发表时间

Response to “Comments on: ‘Inhibition of autotaxin activity with IOA-289 decreases fibrosis in mouse E0771 breast tumors’”对“评论：‘IOA-289抑制自体促动因子活性可减少小鼠E0771乳腺癌的纤维化’”的回应

International Journal of Cancer

IF4.7

2025-06-21

PREAI

Xiaoyun Tang; David N. Brindley

Inhibition of autotaxin activity with IOA-289 decreases fibrosis in mouse E0771 breast tumors IOA-289抑制自分泌运动因子活性可降低小鼠E0771乳腺癌的纤维化程度

INTERNATIONAL JOURNAL OF CANCER

IF4.7

2025-05-09

OAAI

Xiaoyun Tang; Humayara Khan; Karolina Niewola-Staszkowska; Frank Wuest; David N. Brindley

TNF-α induced NF-κB mediated LYRM7 expression modulates the tumor growth and metastatic ability in breast cancer

FREE RADICAL BIOLOGY AND MEDICINE

IF8.2

2024-02-01

PREAI

Shinde, Anjali; Chandak, Nisha; Singh, Jyoti; Roy, Milton; Mane, Minal; Tang, Xiaoyun; Vasiyani, Hitesh; Currim, Fatema; Gohel, Dhruv; Shukla, Shatakshi; Goyani, Shanikumar; Saranga, M. V.; Brindley, David N.; Singh, Rajesh

Lipid phosphate phosphatase-2 promotes tumor growth through increased c-Myc expression

THERANOSTICS

IF13.3

2022-01-01

OAAI

Tang, Xiaoyun; Cromwell, Christopher R.; Liu, Rongzong; Godbout, Roseline; Hubbard, Basil P.; McMullen, Todd P. W.; Brindley, David N.

Physiological and pathological functions of sphingolipids in pregnancy

CELLULAR SIGNALLING

IF3.7

2021-09-01

PREAI

Fakhr, Yuliya; Brindley, David N.; Hemmings, Denise G.

Compromised mitochondrial quality control triggers lipin1-related rhabdomyolysis

CELL REPORTS MEDICINE

IF10.6

2021-08-01

OAAI

Hamel, Yamina; Mauvais, Francois-Xavier; Madrange, Marine; Renard, Perrine; Lebreton, Corinne; Nemazanyy, Ivan; Pelle, Olivier; Goudin, Nicolas; Tang, Xiaoyun; Rodero, Mathieu P.; Tuchmann-Durand, Caroline; Nusbaum, Patrick; Brindley, David N.; van Endert, Peter; de Lonlay, Pascale

FOXQ1 is Differentially Expressed Across Breast Cancer Subtypes with Low Expression Associated with Poor Overall Survival

breast cancer

IF3.4

2021-03-01

OAAI

Elian, Fahed A.; Are, Ubah; Ghosh, Sunita; Nuin, Paulo; Footz, Tim; McMullen, Todd P. W.; Brindley, David N.; Walter, Michael A.

Role of the autotaxin-lysophosphatidate axis in the development of resistance to cancer therapy

BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

IF3.3

2020-08-01

PREAI

Tang, Xiaoyun; Benesch, Matthew G. K.; Brindley, David N.

Signalling by lysophosphatidate and its health implications

LIPID MEDIATORS

IF0

2020-05-26

PREAI

Hemmings, Denise G.; Brindley, David N.

FOXQ1 is differentially expressed across breast cancer subtypes and potentially can serve as a prognostic marker

FASEB JOURNAL

IF4.2

2020-04-16

OAAI

Elian, Fahed; Are, Ubah; Nuin, Paulo; Footz, Tim; Brindley, David; McMullen, Todd; Walter, Michael

Inhibition of Autotaxin with GLPG1690 Increases the Efficacy of Radiotherapy and Chemotherapy in a Mouse Model of Breast Cancer

MOLECULAR CANCER THERAPEUTICS

IF5.5

2020-01-03

OAAI

Tang, Xiaoyun; Wuest, Melinda; Benesch, Matthew G. K.; Dufour, Jennifer; Zhao, YuanYuan; Curtis, Jonathan M.; Monjardet, Alain; Heckmann, Bertrand; Murray, David; Wuest, Frank; Brindley, David N.

Increasing the low lipid phosphate phosphatase 1 activity in breast cancer cells decreases transcription by AP-1 and expressions of matrix metalloproteinases and cyclin D1/D3

THERANOSTICS

IF13.3

2019-01-01

OAAI

Tang, Xiaoyun; McMullen, Todd P. W.; Brindley, David N.

Lipin 2/3 phosphatidic acid phosphatases maintain phospholipid homeostasis to regulate chylomicron synthesis

JOURNAL OF CLINICAL INVESTIGATION

IF13.6

2018-12-03

OAAI

Zhang, Peixiang; Csaki, Lauren S.; Ronquillo, Emilio; Baufeld, Lynn J.; Lin, Jason Y.; Gutierrez, Alexis; Dwyer, Jennifer R.; Brindley, David N.; Fong, Loren G.; Tontonoz, Peter; Young, Stephen G.; Reue, Karen

Dexamethasone decreases the autotaxin-lysophosphatidate-inflammatory axis in adipose tissue: implications for the metabolic syndrome and breast cancer

FASEB JOURNAL

IF4.2

2018-09-07

PREAI

Meng, Guanmin; Tang, Xiaoyun; Yang, Zelei; Zhao, YuanYuan; Curtis, Jonathan M.; McMullen, Todd P. W.; Brindley, David N.

Sexual dimorphism of metabolic and vascular dysfunction in aged mice and those lacking the sphingosine 1-phosphate receptor 3

EXPERIMENTAL GERONTOLOGY

IF4.3

2017-12-01

PREAI

Cao, Amanda T.; Mackova, Martina; Kerage, Daniel; Brindley, David N.; Hemmings, Denise G.

Normal human adipose tissue functions and differentiation in patients with biallelic LPIN1 inactivating mutations

JOURNAL OF LIPID RESEARCH

IF4.1

2017-12-01

OAAI

Pelosi, Michele; Testet, Eric; Le Lay, Soazig; Dugail, Isabelle; Tang, Xiaoyun; Mabilleau, Guillaume; Hamel, Yamina; Madrange, Marine; Blanc, Thomas; Odent, Thierry; McMullen, Todd P. W.; Alfo, Marco; Brindley, David N.; de Lonlay, Pascale

Lysophosphatidate Signaling: The Tumor Microenvironment's New Nemesis

TRENDS IN CANCER

IF17.5

2017-11-01

PREAI

Benesch, Matthew G. K.; Yang, Zelei; Tang, Xiaoyun; Meng, Guanmin; Brindley, David N.

Implications for breast cancer treatment from increased autotaxin production in adipose tissue after radiotherapy

FASEB JOURNAL

IF4.2

2017-09-19

PREAI

Meng, Guanmin; Tang, Xiaoyun; Yang, Zelei; Benesch, Matthew G. K.; Marshall, Alison; Murray, David; Hemmings, Denise G.; Wuest, Frank; McMullen, Todd P. W.; Brindley, David N.

Doxycycline attenuates breast cancer related inflammation by decreasing plasma lysophosphatidate concentrations and inhibiting NF-κB activation

MOLECULAR CANCER

IF33.9

2017-02-08

OAAI

Tang, Xiaoyun; Wang, Xianyan; Zhao, Yuan Y.; Curtis, Jonathan M.; Brindley, David N.

PDGFRα Regulates Follicular Cell Differentiation Driving Treatment Resistance and Disease Recurrence in Papillary Thyroid Cancer

EBIOMEDICINE

IF10.8

2016-10-01

OAAI

Lopez-Campistrous, Ana; Adewuyi, Esther Ekpe; Benesch, Matthew G. K.; Ko, Yi Man; Lai, Raymond; Thiesen, Aducio; Dewald, Jay; Wang, Peng; Chu, Karen; Ghosh, Sunita; Williams, David C.; Vos, Larissa J.; Brindley, David N.; McMullen, Todd P. W.

研究方向