Michel Chrétien - Publications, H-index & Citations

Michel Chrétien

lab

88H指数

580论文数

2.8W被引数

收录论文 80

发表时间

Gender differences in the plasma profiles of proprotein convertase subtilisin/kexin-type 9 (PCSK9), soluble low-density lipoprotein receptor (sLDLR), total cholesterol, and triglycerides in patients with colorectal cancer liver metastases: diagnostic and prognostic implications 结直肠癌肝转移患者中前蛋白转化酶枯草溶菌素/Kexin型9（PCSK9）、可溶性低密度脂蛋白受体（sLDLR）、总胆固醇和甘油三酯血浆谱的性别差异：诊断和治疗意义

Lipids in Health and Disease

IF4.2

2026-05-25

OAAI

Clara Lafortune; Yara Haddad; Mieczyslaw Marcinkiewicz; Michel Chrétien; Simon Turcotte; Majambu Mbikay

Multilevel Residual Complexity Analysis Reveals Origin of Nanomolar Antiviral Bioactives of “Isoquercitrin”多级残余复杂性分析揭示了“异槲皮苷”纳摩尔级抗病毒生物活性物质的来源

Journal of Natural Products

IF3.6

2026-04-10

OAAI

Daniela Rebollar-Ramos; Annie V. Roy; J. Brent Friesen; Guy Harris; Shao-Nong Chen; Michael Chan; Shihua He; Guodong Liu; Wenjun Zhu; Logan Banadyga; James B. McAlpine; Michel Chrétien; Majambu Mbikay; Guido F. Pauli

In Memoriam Professor Philippe Crine: a hero for children with hypophosphatasia

JOURNAL OF BONE AND MINERAL RESEARCH

IF5.9

2024-04-16

OAAI

Chretien, Michel; Hoang, Trang; Bouvier, Michel; Marcinkiewicz, Mieczyslaw; Whyte, Michael; Rockman-Greenberg, Cheryl

Quercetin inhibits SARS-CoV-2 infection and prevents syncytium formation by cells co-expressing the viral spike protein and human ACE2 槲皮素抑制SARS-CoV-2感染，并通过共表达病毒刺突蛋白和人ACE2的细胞防止合胞体形成

VIROLOGY JOURNAL

IF3.8

2024-01-25

OAAI

Roy, Annie V.; Chan, Michael; Banadyga, Logan; He, Shihua; Zhu, Wenjun; Chretien, Michel; Mbikay, Majambu

Native low-density lipoproteins are priming signals of the NLRP3 inflammasome/interleukin-1β pathway in human adipose tissue and macrophages

SCIENTIFIC REPORTS

IF3.9

2023-11-01

OAAI

Bissonnette, Simon; Lamantia, Valerie; Ouimet, Benjamin; Cyr, Yannick; Devaux, Marie; Rabasa-Lhoret, Remi; Chretien, Michel; Saleh, Maya; Faraj, May

Deletion of the gene encoding proprotein convertase 5/6 causes early embryonic lethality in the mouse 编码前蛋白转化酶5/6的基因缺失导致小鼠早期胚胎致死

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-27

OAAI

Essalmani, R; Hamelin, J; Marcinkiewicz, J; Chamberland, A; Mbikay, M; Chrétien, M; Seidah, NG; Prat, A

Intracellular Proprotein convertase subtilisin/kexin type 9: Recruitment and regulatory role in mitochondrial architecture and bioenergetic

BRITISH JOURNAL OF SURGERY

IF8.7

2022-06-01

PREAI

Gavini, J.; Leuenberger, D.; Yarahmadov, T.; Dommann, N.; Keogh, A.; Melin, N.; Tschan, M.; Nuoffer, J-M; Hertig, D.; Zuber, B.; Odriozola, A.; Tombolini, R.; Chretien, M.; Mbikay, M.; Candinas, D.; Stroka, D.

The loss-of-function PCSK9Q152H variant increases ER chaperones GRP78 and GRP94 and protects against liver injury

JOURNAL OF CLINICAL INVESTIGATION

IF13.6

2021-01-19

OAAI

Lebeau, Paul F.; Wassef, Hanny; Byun, Jae Hyun; Platko, Khrystyna; Ason, Brandon; Jackson, Simon; Dobroff, Joshua; Shetterly, Susan; Richards, William G.; Al-Hashimi, Ali A.; Won, Kevin Doyoon; Mbikay, Majambu; Prat, Annik; Tang, An; Pare, Guillaume; Pasqualini, Renata; Seidah, Nabil G.; Arap, Wadih; Chretien, Michel; Austin, Richard C.

White Adipose Tissue Surface Expression of LDLR and CD36 is Associated with Risk Factors for Type 2 Diabetes in Adults with Obesity

OBESITY

IF4.7

2020-10-11

PREAI

Cyr, Yannick; Bissonnette, Simon; Lamantia, Valerie; Wassef, Hanny; Loizon, Emmanuelle; Ngo Sock, Emilienne T.; Vidal, Hubert; Mayer, Gaetan; Chretien, Michel; Faraj, May

The enigma of soluble LDLR: could inflammation be the key?

LIPIDS IN HEALTH AND DISEASE

IF4.2

2020-02-03

OAAI

Mbikay, Majambu; Mayne, Janice; Chretien, Michel

Associations Between Soluble LDLR and Lipoproteins in a White Cohort and the Effect of PCSK9 Loss-of-Function

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

IF5.1

2018-06-21

OAAI

Mayne, Janice; Ooi, Teik Chye; Tepliakova, Lioudmila; Seebun, Deeptee; Walker, Krystal; Mohottalage, Dhanuddara; Ning, Zhibin; Abujrad, Hussein; Mbikay, Majambu; Wassef, Hanny; Chretien, Michel; Figeys, Daniel

The ever-expanding saga of the proprotein convertases and their roles in body homeostasis: emphasis on novel proprotein convertase subtilisin kexin number 9 functions and regulation

CURRENT OPINION IN LIPIDOLOGY

IF4.6

2018-04-01

PREAI

Seidah, Nabil G.; Chretien, Michel; Mbikay, Majambu

The Effect of PCSK9 Loss-of-Function Variants on the Postprandial Lipid and ApoB-Lipoprotein Response

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

IF5.1

2017-06-30

OAAI

Ooi, Teik Chye; Krysa, Jacqueline A.; Chaker, Seham; Abujrad, Hussein; Mayne, Janice; Henry, Kathy; Cousins, Marion; Raymond, Angela; Favreau, Colette; Taljaard, Monica; Chretien, Michel; Mbikay, Majambu; Proctor, Spencer D.; Vine, Donna F.

Prophylactic Efficacy of Quercetin 3-β-O-D-Glucoside against Ebola Virus Infection

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

IF4.5

2016-09-01

OAAI

Qiu, Xiangguo; Kroeker, Andrea; He, Shihua; Kozak, Robert; Audet, Jonathan; Mbikay, Majambu; Chretienc, Michel

60 YEARS OF POMC From the prohormone theory to pro-opiomelanocortin and to proprotein convertases (PCSK1 to PCSK9)

JOURNAL OF MOLECULAR ENDOCRINOLOGY

IF3.8

2016-05-01

OAAI

Chretien, Michel; Mbikay, Majambu

The apoB-to-PCSK9 ratio: A new index for metabolic risk in humans

JOURNAL OF CLINICAL LIPIDOLOGY

IF4.6

2015-09-01

PREAI

Wassef, Hanny; Bissonnette, Simon; Saint-Pierre, Nathalie; Lamantia, Valerie; Cyr, Yannick; Chretien, Michel; Faraj, May

Relationship between testosterone, estradiol and circulating PCSK9: Cross-sectional and interventional studies in humans

CLINICA CHIMICA ACTA

IF2.9

2015-06-01

PREAI

Ooi, T. C.; Raymond, A.; Cousins, M.; Favreau, C.; Taljaard, M.; Gavin, C.; Jolly, E. E.; Malone, S.; Eapen, L.; Chretien, M.; Mbikay, M.; Mayne, J.

β-Estradiol results in a proprotein convertase subtilisin/kexin type 9-dependent increase in low-density lipoprotein receptor levels in human hepatic HuH7 cells

FEBS JOURNAL

IF4.2

2015-05-18

OAAI

Starr, Amanda E.; Lemieux, Valerie; Noad, Jenny; Moore, Jasmine I.; Dewpura, Thilina; Raymond, Angela; Chretien, Michel; Figeys, Daniel; Mayne, Janice

Variable effects of gender and Western diet on lipid and glucose homeostasis in aged PCSK9-deficient C57BL/6 mice

JOURNAL OF DIABETES

IF3.7

2014-03-27

OAAI

Mbikay, Majambu; Sirois, Francine; Gyamera-Acheampong, Charles; Wang, Gen-Sheng; Rippstein, Peter; Chen, Andrew; Mayne, Janice; Scott, Fraser. W.; Chretien, Michel

PCSK9: A Key Modulator of Cardiovascular Health

CIRCULATION RESEARCH

IF16.2

2014-03-14

496

OAAI

Seidah, Nabil G.; Awan, Zuhier; Chretien, Michel; Mbikay, Majambu

研究方向