未登录Therapeutic Antibody-Induced Vascular Toxicity Due to Off-Target Activation of Nitric Oxide in Cynomolgus Monkeys
Pai, Rama; Ma, Ning; Connor, Anu V.; Danilenko, Dimitry M.; Tarrant, Jacqueline M.; Salvail, Dany; Wong, Lisa; Hartley, Dylan P.; Misner, Dinah; Stefanich, Eric; Wu, Yan; Chen, Yongmei; Wang, Hong; Dambach, Donna M.
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收藏Antibody-Mediated Inhibition of Fibroblast Growth Factor 19 Results in Increased Bile Acids Synthesis and Ileal Malabsorption of Bile Acids in Cynomolgus Monkeys
Pai, Rama; French, Dorothy; Ma, Ning; Hotzel, Kathy; Plise, Emile; Salphati, Laurent; Setchell, Kenneth D. R.; Ware, Joseph; Lauriault, Veronique; Schutt, Leah; Hartley, Dylan; Dambach, Donna
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收藏Phosphorous Dysregulation Induced by MEK Small Molecule Inhibitors in the Rat Involves Blockade of FGF-23 Signaling in the Kidney
Diaz, Dolores; Allamneni, Krishna; Tarrant, Jacqueline M.; Lewin-Koh, Sock-Cheng; Pai, Rama; Dhawan, Preeti; Cain, Gary R.; Kozlowski, Cleopatra; Hiraragi, Hajime; La, Nghi; Hartley, Dylan P.; Ding, Xiao; Dean, Brian J.; Bheddah, Sheila; Dambach, Donna M.
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收藏Aging gastropathy-novel mechanisms: Hypoxia, up-regulation of multifunctional phosphatase PTEN, and proapoptotic factors
Tarnawski, Andrzej; Pai, Rama; Deng, Xiaoming; Ahluwalia, Amrita; Khomenko, Tetyana; Tanigawa, Tetsuya; Akahoshi, Tomohiko; Sandor, Zsuzsanna; Szabo, Sandor
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收藏Targeting FGF19 inhibits tumor growth in colon cancer xenograft and FGF19 transgenic hepatocellular carcinoma models靶向FGF19抑制结肠癌异种移植和FGF19转基因肝癌模型中的肿瘤生长
Desnoyers, Lr; Pai, R.; Ferrando, Re; Hotzel, K.; Le, T.; Ross, J.; Carano, R.; D'Souza, A.; Qing, J.; Mohtashemi, I.; Ashkenazi, A.; French, Dm
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收藏Defective mitogen-activated protein kinase (ERK2) signaling in gastric mucosa of portal hypertensive rats: Potential therapeutic implications
Kawanaka, H; Tomikawa, M; Jones, MK; Szabo, IL; Pai, R; Baatar, D; Tsugawa, K; Sugimachi, K; Sarfeh, J; Tarnawski, AS
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收藏Despite activation of EGF-receptor-ERK signaling pathway, epithelial proliferation is impaired in portal hypertensive gastric mucosa -: Relevance of MKP-1, c-fos, c-myc and cyclin D1 expression
Kawanaka, H; Tomikawa, M; Baatar, D; Jones, MK; Pai, R; Szabo, IL; Sugimachi, K; Sarfeh, IJ; Tarnawski, AS
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收藏Gene therapy for gastric ulcers with single local injection of naked DNA encoding VEGF and angiopoietin-1
Jones, MK; Kawanaka, H; Baatar, D; Szabó, IL; Tsugawa, K; Pai, R; Koh, GY; Kim, I; Sarfeh, IJ; Tarnawski, AS
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