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S

Stefaan De Koker

etherna immunotherapies, niel, 2845 belgium
H指数:40
被引数:5,750

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荣誉奖项

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Next-Generation Bio-Reducible Lipids Enable Enhanced Vaccine Efficacy in Malaria and Primate Models

下一代生物可还原脂质在疟疾和非人灵长类动物模型中增强了疫苗效果

Advanced Functional Materials
IF19
2025-09-160
OAAI
Ruben De Coen; Sabah Kasmi; Shrinivas Dumbre; Lies Baekens; Elise Seynaeve; Louise Van den Hauwe; Niccolò Cantini; Aello Garantoudi; Filipe Branco Madeira; Alain Marrot; Emma Tuypens; Sofie Seghers; Anna Kuchmiy; Elisabeth Brabants; Bart Vanderborght; Ine Maes; Sarah Vandenberghe; Jessica Filtjens; Alícia Gordún Peiró; Daliya Kancheva; Ayla Debraekeleer; Florence Lambolez; Emily De Lombaerde; Yong Chen; Rafael Miyazawa Martins; Pauline Formaglio; Damya Laoui; Sofie Deschoemaeker; Bruno G. De Geest; Rogerio Amino; Stefaan De Koker
Intratumoral delivery of lipid nanoparticle-formulated mRNA encoding IL-21, IL-7, and 4-1BBL induces systemic anti-tumor immunity
NATURE COMMUNICATIONS
IF15.7
2024-12-060
OAAI
Hamouda, Ahmed E. I.; Filtjens, Jessica; Brabants, Elisabeth; Kancheva, Daliya; Debraekeleer, Ayla; Brughmans, Jan; Jacobs, Lotte; Bardet, Pauline M. R.; Knetemann, Elisabeth; Lefesvre, Pierre; Allonsius, Lize; Gontsarik, Mark; Varela, Ismael; Crabbe, Marian; Clappaert, Emile J.; Cappellesso, Federica; Caro, Aarushi A.; Peiro, Alicia Gordun; Fredericq, Luna; Hadadi, Eva; Senti, Mariona Estape; Schiffelers, Raymond; van Grunsven, Leo A.; Nana, Frank Aboubakar; De Geest, Bruno G.; Deschoemaeker, Sofie; De Koker, Stefaan; Lambolez, Florence; Laoui, Damya
Combinatorial Screening of Biscarbamate Ionizable Lipids Identifies a Low Reactogenicity Lipid for Lipid Nanoparticle mRNA Delivery

双氨基甲酸酯可电离脂质的组合筛选确定了用于脂质纳米颗粒mRNA递送的低反应原性脂质

ADVANCED FUNCTIONAL MATERIALS
IF19
2024-02-016
OA
De Lombaerde, Emily; Chen, Yong; Ye, Tingting; Deckers, Julie; Mencarelli, Giulia; De Swarte, Kim; Lauwers, Heleen; De Coen, Ruben; Kasmi, Sabah; Bevers, Sanne; Kuchmiy, Anna; Bogaert, Bram; Baekens, Lies; Zhong, Zifu; Lamoot, Alexander; Sanders, Niek N.; Lambrecht, Bart N.; Baptista, Antonio P.; De Koker, Stefaan; De Geest, Bruno G.
mRNA-LNP vaccines tuned for systemic immunization induce strong antitumor immunity by engaging splenic immune cells
MOLECULAR THERAPY
IF12
2022-09-0174
OAAI
Bevers, Sanne; Kooijmans, Sander A. A.; Van de Velde, Elien; Evers, Martijn J. W.; Seghers, Sofie; Gitz-Francois, Jerney J. J. M.; van Kronenburg, Nicky C. H.; Fens, Marcel H. A. M.; Mastrobattista, Enrico; Hassler, Lucie; Sork, Helena; Lehto, Taavi; Ahmed, Kariem E.; El Andaloussi, Samir; Fiedler, Katja; Breckpot, Karine; Maes, Michael; Van Hoorick, Diane; Bastogne, Thierry; Schiffelers, Raymond M.; De Koker, Stefaan
Lipid-Polyglutamate Nanoparticle Vaccine Platform
ACS APPLIED MATERIALS & INTERFACES
IF8.2
2021-01-2825
OA
Van Lysebetten, Dorien; Malfanti, Alessio; Deswarte, Kim; Koynov, Kaloian; Golba, Bianka; Ye, Tingting; Zhong, Zifu; Kasmi, Sabah; Lamoot, Alexander; Chen, Yong; Van Herck, Simon; Lambrecht, Bart N.; Sanders, Niek N.; Lienenklaus, Stefan; David, Sunil A.; Vicent, Maria J.; De Koker, Stefaan; De Geest, Bruno G.
Dendritic Cell Targeting mRNA Lipopolyplexes Combine Strong Antitumor T-Cell Immunity with Improved Inflammatory Safety

树突状细胞靶向mRNA脂质复合物结合了强大的抗肿瘤T细胞免疫和改善的炎症安全性

ACS NANO
IF16
2018-09-26111
OAAI
Van der Jeught, Kevin; De Koker, Stefaan; Bialkowski, Lukasz; Heirman, Carlo; Joe, Patrick Tjok; Perche, Federico; Maenhout, Sarah; Bevers, Sanne; Broos, Katrijn; Deswarte, Kim; Malard, Virginie; Hammad, Hamida; Baril, Patrick; Benvegnu, Thierry; Jaffres, Paul-Alain; Kooijmans, Sander A. A.; Schiffelers, Raymond; Lienenklaus, Stefan; Midoux, Patrick; Pichon, Chantal; Breckpot, Karine; Thielemans, Kris
Arginine-Rich Peptide-Based mRNA Nanocomplexes Efficiently Instigate Cytotoxic T Cell Immunity Dependent on the Amphipathic Organization of the Peptide

基于富含精氨酸的肽的mRNA纳米复合物有效地激发依赖于肽的两亲性组织的细胞毒性T细胞免疫

ADVANCED HEALTHCARE MATERIALS
IF9.6
2017-04-24146
PREAI
Udhayakumar, Vimal K.; De Beuckelaer, Ans; McCaffrey, Joanne; McCrudden, Cian M.; Kirschman, Jonathan L.; Vanover, Daryll; Van Hoecke, Lien; Roose, Kenny; Deswarte, Kim; De Geest, Bruno G.; Lienenklaus, Stefan; Santangelo, Philip J.; Grooten, Johan; McCarthy, Helen O.; De Koker, Stefaan

研究方向

暂未获取到该数据
B
Bruno G. De Geest
H 指数:65论文数:313被引数:1.5万
J
Johan Grooten
H 指数:57论文数:261被引数:1.0万
B
Bart N. Lambrecht
H 指数:123论文数:763被引数:6.3万
S
Stefan Lienenklaus
H 指数:49论文数:167被引数:8,487
K
Kim Deswarte
H 指数:33论文数:85被引数:6,976
N
Niek N. Sanders
H 指数:58论文数:225被引数:1.2万
X
Xavier Saelens
H 指数:66论文数:292被引数:1.4万
Z
Zifu Zhong
H 指数:20论文数:60被引数:1,556
L
Lien Van Hoecke
H 指数:27论文数:78被引数:2,827
T
Thomas Naessens
H 指数:17论文数:29被引数:1,349