Annamaria Fra - Publications, H-index & Citations

Annamaria Fra

University of Brescia

29H指数

62论文数

3.6K被引数

收录论文 20

发表时间

High-resolution characterization of ex vivo AAT polymers by solution-state NMR spectroscopy 通过溶液态NMR光谱法对离体AAT聚合物的高分辨率表征

SCIENCE ADVANCES

IF12.5

2025-05-09

PREAI

Lowen, Sarah M.; Waudby, Christopher A.; Jagger, Alistair M.; Aldobiyan, Ibrahim; Laffranchi, Mattia; Fra, Annamaria; Christodoulou, John; Irving, James A.; Lomas, David A.

Identification of an exosite at the neutrophil elastase/alpha-1-antitrypsin interface

FEBS JOURNAL

IF4.2

2025-01-08

OAAI

Gangemi, Roberto; Bignotti, Mattia; Denardo, Andrea; Pearce, Claudia N.; Ronzoni, Riccardo; Lomas, David A.; Irving, James A.; Fra, Annamaria; Gangemi, Fabrizio

Quantification of circulating alpha-1-antitrypsin polymers associated with different SERPINA1 genotypes

CLINICAL CHEMISTRY AND LABORATORY MEDICINE

IF3.7

2024-02-27

PREAI

Balderacchi, Alice M.; Bignotti, Mattia; Ottaviani, Stefania; Denardo, Andrea; Barzon, Valentina; Ben Khlifa, Emna; Vailati, Guido; Piloni, Davide; Benini, Federica; Corda, Luciano; Corsico, Angelo G.; Ferrarotti, Ilaria; Fra, Annamaria

Probing of the reactive center loop region of alpha-1-antitrypsin by mutagenesis predicts new type-2 dysfunctional variants

CELLULAR AND MOLECULAR LIFE SCIENCES

IF6.2

2023-12-13

OAAI

Denardo, Andrea; Ben Khlifa, Emna; Bignotti, Mattia; Giuliani, Roberta; D'Acunto, Emanuela; Miranda, Elena; Irving, James A.; Fra, Annamaria

Comprehensive Clinical Diagnostic Pipelines Reveal New Variants in Alpha-1 Antitrypsin Deficiency

AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

IF5.3

2023-09-01

OAAI

Ottaviani, Stefania; Bartoli, Giulia; Carroll, Tomas P.; Gangemi, Fabrizio; Balderacchi, Alice M.; Barzon, Valentina; Corino, Alessandra; Piloni, Davide; McElvaney, Noel G.; Corsico, Angelo G.; Irving, James A.; Fra, Annamaria; Ferrarotti, Ilaria

Human iPSC-Derived 3D Hepatic Organoids in a Miniaturized Dynamic Culture System

BIOMEDICINES

IF3.9

2023-07-26

OAAI

Calamaio, Serena; Serzanti, Marialaura; Boniotti, Jennifer; Fra, Annamaria; Garrafa, Emirena; Cominelli, Manuela; Verardi, Rosanna; Poliani, Pietro Luigi; Dotti, Silvia; Villa, Riccardo; Mazzoleni, Giovanna; Dell'Era, Patrizia; Steimberg, Nathalie

Clinical and molecular characterisation of new variants associated to alpha-1-antitrypsin deficiency

EUROPEAN RESPIRATORY JOURNAL

IF21

2022-12-01

PREAI

Balderacchi, A. M.; Bartoli, G.; Ottaviani, S.; Barzon, V; Corino, A.; Carrol, T. P.; Piloni, D.; Mcelvaney, N. G.; Corsico, A. G.; Fra, A.; Ferrarotti, I; Barzon, V

Neuroserpin: structure, function, physiology and pathology

CELLULAR AND MOLECULAR LIFE SCIENCES

IF6.2

2021-08-17

OAAI

D'Acunto, Emanuela; Fra, Annamaria; Visentin, Cristina; Manno, Mauro; Ricagno, Stefano; Galliciotti, Giovanna; Miranda, Elena

The molecular species responsible for α1-antitrypsin deficiency are suppressed by a small molecule chaperone

FEBS JOURNAL

IF4.2

2020-11-11

OAAI

Ronzoni, Riccardo; Heyer-Chauhan, Nina; Fra, Annamaria; Pearce, Andrew C.; Rudiger, Martin; Miranda, Elena; Irving, James A.; Lomas, David A.

Quantification of circulating alpha-1-antitrypsin polymers in dried blood spots

EUROPEAN RESPIRATORY JOURNAL

IF21

2020-10-28

PREAI

Ferrarotti, Ilaria; Ottaviani, Stefania; Laffranchi, Mattia; Barzon, Valentina; Balderacchi, Alice Maria; Levi, Guido; Corsico, Angelo Guido; Corda, Luciano; Benini, Federica; Fra, Anna Maria

Identification and characterisation of twenty-two novel SERPINA1 pathological mutations

EUROPEAN RESPIRATORY JOURNAL

IF21

2020-10-28

OAAI

Ottaviani, Stefania; Fra, Anna Maria; Balderacchi, Alice Maria; Barzon, Valentina; Carroll, Tomas Patrick; Piloni, Davide; Mariani, Francesca; Mc Elvaney, Noel Gerard; Corsico, Angelo Guido; Ferrarotti, Ilaria

Intrahepatic heteropolymerization of M and Z alpha-1-antitrypsin

JCI INSIGHT

IF6.1

2020-07-23

OAAI

Laffranchi, Mattia; Elliston, Emma L. K.; Miranda, Elena; Perez, Juan; Ronzoni, Riccardo; Jagger, Alistair M.; Heyer-Chauhan, Nina; Brantly, Mark L.; Fra, Annamaria; Lomas, David A.; Irving, James A.

ALPHA1-ANTITRYPSIN DEFICIENCY: A 25-YEAR EXPERIENCE ALPHA1-ANTITRYPSIN不足: 25年的经验

CHEST

IF8.6

2020-06-01

OAAI

Levi, G.; Corda, L.; Benini, F.; Arici, M.; Rocchetti, C.; Ciarfaglia, M.; Fra, A.; Fuoti, M.; Pini, L.; Laffranchi, M.; Orzes, N.; Uccelli, S.; Cettolo, F.; Giordani, J.; Tantucci, C.

Real-world clinical applicability of pathogenicity predictors assessed on SERPINA1 mutations in alpha-1-antitrypsin deficiency

HUMAN MUTATION

IF3.7

2018-06-28

OAAI

Giacopuzzi, Edoardo; Laffranchi, Mattia; Berardelli, Romina; Ravasio, Viola; Ferrarotti, Ilaria; Gooptu, Bibek; Borsani, Giuseppe; Fra, Annamaria

Heteropolymerization of α-1-antitrypsin mutants in cell models mimicking heterozygosity

HUMAN MOLECULAR GENETICS

IF3.2

2018-03-10

OAAI

Laffranchi, Mattia; Berardelli, Romina; Ronzoni, Riccardo; Lomas, David A.; Fra, Annamaria

Intermittent C1-Inhibitor Deficiency Associated with Recessive Inheritance: Functional and Structural Insight

SCIENTIFIC REPORTS

IF3.9

2018-01-17

OAAI

Caccia, Sonia; Suffritti, Chiara; Carzaniga, Thomas; Berardelli, Romina; Berra, Silvia; Martorana, Vincenzo; Fra, Annamaria; Drouet, Christian; Cicardi, Marco

The pathological Trento variant of alpha-1-antitrypsin (E75V) shows nonclassical behaviour during polymerization

FEBS JOURNAL

IF4.2

2017-06-08

OAAI

Miranda, Elena; Ferrarotti, Ilaria; Berardelli, Romina; Laffranchi, Mattia; Cerea, Marta; Gangemi, Fabrizio; Haq, Imran; Ottaviani, Stefania; Lomas, David A.; Irving, James A.; Fra, Annamaria

Polymers of Z α1-antitrypsin are secreted in cell models of disease

EUROPEAN RESPIRATORY JOURNAL

IF21

2016-02-04

OAAI

Fra, Annamaria; Cosmi, Francesca; Ordonez, Adriana; Berardelli, Romina; Perez, Juan; Guadagno, Noemi A.; Corda, Luciano; Marciniak, Stefan J.; Lomas, David A.; Miranda, Elena

Aberrant disulphide bonding contributes to the ER retention of alpha1-antitrypsin deficiency variants

HUMAN MOLECULAR GENETICS

IF3.2

2015-12-08

OAAI

Ronzoni, Riccardo; Berardelli, Romina; Medicina, Daniela; Sitia, Roberto; Gooptu, Bibek; Fra, Anna Maria

Progressively impaired proteasomal capacity during terminal plasma cell differentiation

EMBO JOURNAL

IF8.3

2006-02-23

145

OAAI

Cenci, S; Mezghrani, A; Cascio, P; Bianchi, G; Cerruti, F; Fra, A; Lelouard, H; Masciarelli, S; Mattioli, L; Oliva, L; Orsi, A; Pasqualetto, E; Pierre, P; Ruffato, E; Tagliavacca, L; Sitia, R

研究方向