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H

Hyukjin Lee

seoul national university

48H指数
206论文数
9.6K被引数
收录论文 103
发表时间
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Mutation-agnostic base editing of the progerin farnesylation site rescues Hutchinson-Gilford progeria syndrome phenotypes in neuromuscular organoids针对早衰蛋白法尼基化位点的突变非依赖性碱基编辑在神经肌肉类器官中拯救了贺金-吉尔福德早衰综合征表型
errNature Communications
IF15.7
err2026-08-31
err0
errOAAI
errDong-Woo Kim; Eun-Ji Kwon; Beom-Jin Jeon; Dong-Hyeok Kwon; Goo Jang; Youngyoon Yoon; Yuna Hwang; Hyukjin Lee; Hyuk-Jin Cha
err分享
err收藏
Inflammatory and immune-mediated toxicity of lipid nanoparticles脂质纳米颗粒的炎症和免疫介导毒性
errBIOMEDICINE & PHARMACOTHERAPY
IF7.5
err2026-04-19
err0
errOAAI
errSoyeon Kim; Choeun Park; Yeji Lee; Kunwoo Lee; Hyukjin Lee; Kyuri Lee
err分享
err收藏
mRNA based in vivo MG1113 antibody production as a potential therapeutic approach for hemophilia基于mRNA的在体MG1113抗体生产作为一种治疗血友病的潜在方法
errJournal of Controlled Release
IF11.5
err2025-12-07
err0
errOAAI
errMiyoung. Oh; Yujeong. Jeong; Hyein. Jung; Yongjoo. Byeon; Heechun. Kwak; Songseop. Kim; Wonhyo. Seo; Jaesung. Jung; Hyukjin. Lee
err分享
err收藏
RNA stability enhancers for durable base-modified mRNA therapeuticsRNA稳定性增强剂用于持久的碱基修饰mRNA治疗
errNature Biotechnology
IF41.7
err2025-11-07
err0
PREAI
errSoo-Jin Jung; Jenny J. Seo; Sunghan Lee; Seong-In Hyun; Ji-eun Lee; Sojeong Lee; Yeji Lee; Hyeshik Chang; Hyukjin Lee; Jin-Hong Kim; V. Narry Kim
err分享
err收藏
Advances in mRNA-Lipid Nanoparticle Engineering for Immune Cell Targeting and Immune ModulationmRNA-脂质纳米粒工程在免疫细胞靶向和免疫调控方面的进展
errSmall Methods
IF9.1
err2025-09-16
err0
PREAI
errCheesue Kim; Yeji Lee; Hyukjin Lee; Byung-Soo Kim
err分享
err收藏
Advances in the rational design of ionizable lipids for mRNA therapeutics可电离脂质在mRNA疗法中理性设计的进展
errmaterials today advances
IF22
err2025-07-31
err0
PREAI
errYeji Lee; Kaiyuan Guo; Miyoung Oh; Eunbin Kim; Yujeong Jeong; Youngyoon Yoon; Yelim Choi; Yuna Hwang; Yongjoo Byeon; Yizhou Dong; Hyukjin Lee
err分享
err收藏
Development of lipid nanoparticle formulation for intramuscular administration of mRNA vaccine against respiratory syncytial virus
errJOURNAL OF PHARMACEUTICAL INVESTIGATION
IF5.1
err2025-01-22
err0
PREAI
errJang, Eunju; Lee, Yeji; Ko, Eunju; Jeong, Michaela; Chang, Jun; Lee, Hyukjin
err分享
err收藏
GTSE1-driven ZEB1 stabilization promotes pulmonary fibrosis through the epithelial-to-mesenchymal transition
errMOLECULAR THERAPY
IF12
err2024-11-01
err1
errOAAI
errJin, Hee; Park, So-Yeon; Lee, Ji Eun; Park, Hangyeol; Jeong, Michaela; Lee, Hyukjin; Cho, Jaeho; Lee, Yun-Sil
err分享
err收藏
Optimization of polyethylene glycol shielding and mannose density on the lipid nanoparticles for efficient delivery to macrophages and spleens
errINTERNATIONAL JOURNAL OF PHARMACEUTICS
IF5.2
err2024-09-01
err1
PREAI
errYeo, Sangho; Lee, Hyeondo; Lee, Junhyuk; Lee, Hyukjin; Mok, Hyejung
err分享
err收藏
Innate immune responses against mRNA vaccine promote cellular immunity through IFN-β at the injection site
errNATURE COMMUNICATIONS
IF15.7
err2024-08-27
err1
errOAAI
errKim, Seongryong; Jeon, Ji Hyang; Kim, Myeonghwan; Lee, Yeji; Hwang, Yun-Ho; Park, Myungsun; Li, C. Han; Lee, Taeyoung; Lee, Jung-Ah; Kim, You-Me; Kim, Dokeun; Lee, Hyukjin; Kim, You-Jin; Kim, V. Narry; Park, Jong-Eun; Yeo, Jinah
err分享
err收藏
Effects of Histidine Oligomers in Lipid Nanoparticles on siRNA Delivery
errMACROMOLECULAR BIOSCIENCE
IF4.1
err2024-06-21
err0
PREAI
errLee, Hyeondo; You, Gayeon; Yeo, Sangho; Lee, Hyukjin; Mok, Hyejung
err分享
err收藏
Development of Lipid Nanoparticle Formulation for the Repeated Administration of mRNA Therapeutics
errBIOMATERIALS RESEARCH
IF9.6
err2024-05-22
err2
errOAAI
errLee, Yeji; Jeong, Michaela; Lee, Gyeongseok; Park, Jeongeun; Jung, Hyein; Im, Seongeun; Lee, Hyukjin
err分享
err收藏
Oligonucleotide therapeutics and their chemical modification strategies for clinical applications
errJOURNAL OF PHARMACEUTICAL INVESTIGATION
IF5.1
err2024-02-29
err4
PREAI
errKim, Hyunsook; Kim, Sujeong; Lee, Dayoung; Lee, Dahye; Yoon, Jiyeon; Lee, Hyukjin
err分享
err收藏
In vivo genome editing using 244-cis LNPs and low-dose AAV achieves therapeutic threshold in hemophilia A mice
errMOLECULAR THERAPY NUCLEIC ACIDS
IF6.1
err2023-12-01
err9
errOAAI
errHan, Jeong Pil; Lee, Yeji; Lee, Jeong Hyeon; Chung, Hye Yoon; Lee, Geon Seong; Nam, Yu Ri; Choi, Myeongjin; Moon, Kyoung-Sik; Lee, Haeshin; Lee, Hyukjin; Yeom, Su Cheong
err分享
err收藏
Immunogenicity of lipid nanoparticles and its impact on the efficacy of mRNA vaccines and therapeutics脂质纳米粒的免疫原性及其对mRNA疫苗和治疗效果的影响
errEXPERIMENTAL AND MOLECULAR MEDICINE
IF12.9
err2023-10-02
err71
errOAAI
errLee, Yeji; Jeong, Michaela; Park, Jeongeun; Jung, Hyein; Lee, Hyukjin
err分享
err收藏
Lipid nanoparticles (LNPs) for in vivo RNA delivery and their breakthrough technology for future applications
errADVANCED DRUG DELIVERY REVIEWS
IF17.6
err2023-09-01
err59
PREAI
errJeong, Michaela; Lee, Yeji; Park, Jeongeun; Jung, Hyein; Lee, Hyukjin
err分享
err收藏
In vivo genome editing for hemophilia B therapy by the combination of rebalancing and therapeutic gene knockin using a viral and non-viral vector
errMOLECULAR THERAPY-NUCLEIC ACIDS
IF0
err2023-06-01
err17
errOAAI
errLee, Jeong Hyeon; Han, Jeong Pil; Song, Dong Woo; Lee, Geon Seong; Choi, Beom Seok; Kim, MinJeong; Lee, Yeji; Kim, Seokjoong; Lee, Hyukjin; Yeom, Su Cheong
err分享
err收藏
Novel piperazine-based ionizable lipid nanoparticles allow the repeated dose of mRNA to fibrotic lungs with improved potency and safety基于哌嗪的新型可电离脂质纳米颗粒允许重复剂量的mRNA到纤维化肺，具有改善的效力和安全性
errBIOENGINEERING & TRANSLATIONAL MEDICINE
IF5.7
err2023-05-28
err14
errOAAI
errKim, Minjeong; Jeong, Michaela; Lee, Gyeongseok; Lee, Yeji; Park, Jeongeun; Jung, Hyein; Im, Seongeun; Yang, Joo-Sung; Kim, Kyungjin; Lee, Hyukjin
err分享
err收藏
Development of a Real-Time 6-DOF Motion-Tracking System for Robotic Computer-Assisted Implant Surgery用于机器人计算机辅助植入手术的实时六自由度运动跟踪系统的开发
errSENSORS
IF3.5
err2023-02-22
err10
errOAAI
errSin, Minki; Cho, Jang Ho; Lee, Hyukjin; Kim, Kiyoung; Woo, Hyun Soo; Park, Ji-Man
err分享
err收藏
Efficient Delivery of Globotriaosylceramide Synthase siRNA using Polyhistidine-Incorporated Lipid Nanoparticles
errMACROMOLECULAR BIOSCIENCE
IF4.1
err2023-02-10
err11
PREAI
errKim, In Gyu; Jung, Won Ho; You, Gayeon; Lee, Hyukjin; Shin, Yoo Jin; Lim, Sun Woo; Chung, Byung Ha; Mok, Hyejung
err分享
err收藏

研究方向

暂无研究方向
合作学者
合作期刊
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H 指数: 119 · 论文数: 466
I
Ick Chan Kwon
H 指数: 112 · 论文数: 536
R
Ru‐Shi Liu
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