Jian Jin - Publications, H-index & Citations

Jian Jin

Jiangnan University

16H指数

62论文数

682被引数

收录论文 22

发表时间

Biophysical and computational characterization identifies FSTL1 as a novel binding target of doxorubicin 生物物理和计算表征鉴定FSTL1为多柔比星的新型结合靶点

Computational Biology and Chemistry

IF3.1

2026-09-29

PREAI

Wang, Wentao; Li, Sen; Cai, Yanfei; Chen, Yun; Zhu, Jingyu; Jin, Jian

Promoting endogenous iron mediated ferroptosis for cancer therapy through gene interference and reactive oxygen species amplification

JOURNAL OF COLLOID AND INTERFACE SCIENCE

IF9.7

2025-12-01

PREAI

Li, Sen; Wang, Wentao; Kou, Shixu; Ding, Xuefeng; Jin, Jian; Yang, Zhaoqi; Hua, Dong

Dumbbell-shape DNA structure activates cGAS-STING pathway for enhanced checkpoint immunotherapy in colorectal cancer 哑铃状DNA结构激活cGAS-STING通路，以增强结直肠癌的检查点免疫疗法

International Journal of Biological Macromolecules

IF8.5

2025-10-20

PREAI

Yu Zhang; Li He; Shixu Kou; Kedong Liu; Zilong He; Jian Jin; Zhaoqi Yang; Teng Wang

Engineering micelles with hydrophilic-lipophilic balance to overcome intestinal barrier for oral therapeutic application 通过调节亲水-亲脂平衡来工程化制备胶束，以克服肠道屏障，实现口服治疗应用。

Materials Today Bio

IF10.2

2025-09-29

OAAI

Kedong Liu; Pi Zhao; Yun Chen; Yu Zhang; Jian Jin; Tao Wan

RSCNN-PseU: random searching-based convolutional neural network model for identifying RNA pseudouridine RSCNN-PseU：基于随机搜索的卷积神经网络模型，用于识别RNA假尿苷

BRIEFINGS IN BIOINFORMATICS

IF7.7

2025-07-01

OAAI

Jin, Jian; Feng, Jie

Identification of novel covalent JAK3 inhibitors through consensus scoring virtual screening: integration of common feature pharmacophore and covalent docking

MOLECULAR DIVERSITY

IF3.8

2024-07-15

PREAI

Qiu, Genhong; Yu, Li; Jia, Lei; Cai, Yanfei; Chen, Yun; Jin, Jian; Xu, Lei; Zhu, Jingyu

Developing a Naive Bayesian Classification Model with PI3Kγ structural features for virtual screening against PI3Kγ: Combining molecular docking and pharmacophore based on multiple PI3Kγ conformations

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

IF5.9

2022-12-01

PREAI

Jiang, Yingmin; Xiong, Wendian; Jia, Lei; Xu, Lei; Cai, Yanfei; Chen, Yun; Jin, Jian; Gao, Mingzhu; Zhu, Jingyu

Investigation into the anti-airway inflammatory role of the PI3K? inhibitor JN-PK1: An in vitro and in vivo study

INTERNATIONAL IMMUNOPHARMACOLOGY

IF4.7

2022-10-01

PREAI

Xiong, Wendian; Jia, Lei; Liang, Junjie; Cai, Yanfei; Chen, Yun; Nie, Yunjuan; Jin, Jian; Zhu, Jingyu

Exploring PI3K? binding preference with Eganelisib, Duvelisib, and Idelalisib via energetic, pharmacophore and dissociation pathway analyses

COMPUTERS IN BIOLOGY AND MEDICINE

IF6.3

2022-08-01

PREAI

Jia, Lei; Wang, Lingling; Jiang, Yingmin; Xu, Lei; Cai, Yanfei; Chen, Yun; Jin, Jian; Sun, Huiyong; Zhu, Jingyu

Discovery of novel selective PI3Kγ inhibitors through combining machine learning-based virtual screening with multiple protein structures and bio-evaluation

JOURNAL OF ADVANCED RESEARCH

IF13

2022-02-01

OAAI

Zhu, Jingyu; Li, Kan; Xu, Lei; Cai, Yanfei; Chen, Yun; Zhao, Xinling; Li, Huazhong; Huang, Gang; Jin, Jian

A multi-conformational virtual screening approach based on machine learning targeting PI3Kγ

MOLECULAR DIVERSITY

IF3.8

2021-06-23

PREAI

Zhu, Jingyu; Jiang, Yingmin; Jia, Lei; Xu, Lei; Cai, Yanfei; Chen, Yun; Zhu, Nannan; Li, Huazhong; Jin, Jian

Integrated molecular modeling techniques to reveal selective mechanisms of inhibitors to PI3Kδ with marketed Idelalisib

CHEMICAL BIOLOGY & DRUG DESIGN

IF3.3

2021-03-13

PREAI

Zhu, Jingyu; Jia, Lei; Jiang, Yingmin; Yu, Qianqian; Xu, Lei; Cai, Yanfei; Chen, Yun; Li, Huazhong; Gang, Huang; Liang, Wenqing; Jin, Jian

Significant improvement in conversion efficiency of isonicotinic acid by immobilization of cells via a novel microsphere preparation instrument

BIORESOURCE TECHNOLOGY

IF9

2021-01-01

PREAI

Qian, Jianying; Gong, Jinsong; Xu, Zhenghong; Jin, Jian; Shi, Jinsong

Targeting phosphatidylinositol 3-kinase gamma (PI3Kγ): Discovery and development of its selective inhibitors

MEDICINAL RESEARCH REVIEWS

IF11.6

2020-12-10

PREAI

Zhu, Jingyu; Li, Kan; Yu, Li; Chen, Yun; Cai, Yanfei; Jin, Jian; Hou, Tingjun

Polymorphs of DP-VPA Solid Solutions and Their Physicochemical Properties

JOURNAL OF PHARMACEUTICAL SCIENCES

IF3.8

2020-07-01

PREAI

Hao, Chao; Jin, Jian; Xiong, Jiaying; Yang, Zhengge; Gao, Lanchang; Ma, Yanqin; Liu, Bi-Feng; Liu, Xin; Chen, Yin; Zhang, Guisen

Theoretical Exploring Selective-Binding Mechanisms of JAK3 by 3D-QSAR, Molecular Dynamics Simulation and Free Energy Calculation

FRONTIERS IN MOLECULAR BIOSCIENCES

IF4

2020-05-27

OAAI

Zhu, Jingyu; Yu, Qianqian; Cai, Yanfei; Chen, Yun; Liu, Hui; Liang, Wenqing; Jin, Jian

Insight into the selective mechanism of phosphoinositide 3-kinase γ with benzothiazole and thiazolopiperidine γ-specific inhibitors by in silico approaches

CHEMICAL BIOLOGY & DRUG DESIGN

IF3.3

2019-01-11

PREAI

Zhu, Jingyu; Li, Kan; Xu, Lei; Jin, Jian

A Novel Complex of Chitosan-Sodium Carbonate and Its Properties

MARINE DRUGS

IF5.4

2018-10-30

OAAI

Qian, Jianying; Wang, Xiaomeng; Shu, Jie; Su, Chang; Gong, Jinsong; Xu, Zhenghong; Jin, Jian; Shi, Jinsong

Theoretical studies on the selective mechanisms of GSK3β and CDK2 by molecular dynamics simulations and free energy calculations

CHEMICAL BIOLOGY & DRUG DESIGN

IF3.3

2016-12-07

PREAI

Zhao, Sufang; Zhu, Jingyu; Xu, Lei; Jin, Jian

Selective Synthesis of Isoquinolines by Rhodium(III)-Catalyzed C-H/N-H Functionalization with α-Substituted Ketones

ORGANIC LETTERS

IF5

2016-07-21

PREAI

Li, Jie; Zhang, Zhao; Tang, Mengyao; Zhang, Xiaolei; Jin, Jian

研究方向