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D

Devrim Kilinc

univ. lille and inserm and chu lille and institut pasteur de lille
H指数:22
被引数:1,486

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PLCG2 downregulation impairs synaptic function and increases Alzheimer’s disease hallmarks in neuronal cultures

PLCγ2下调损害突触功能并增加神经元培养物中的阿尔茨海默病标志物

Nature Genetics
IF29
2026-08-140
OA
Audrey Coulon; Florian Rabiller; Mari Takalo; Avishek Roy; Alexandre Pelletier; Henna Martiskainen; Dolores Siedlecki-Wullich; Nina Lannette-Weimann; Naďa Majerníková; Arthur Grenon; Vance Gao; Anaël Erhardt; Anne Pernodet; Morgane Lemaire; Floriane Limoge; Pauline Walle; Tiago Mendes; Karine Guyot; Célia Lemeu; Lukas-Iohan Carvalho; Ana Raquel Melo de Farias; Marc Hulsman; Chloé Najdek; Alejandra Freire-Regatillo; Orthis Saha; Philippe Amouyel; Camille Charbonnier; Jean-François Deleuze; Orio Dols-Icardo; Heli Jeskanen; Roosa-Maria Willman; Teemu Kuulasmaa; Mitja Kurki; John Hardy; Sami Heikkinen; Henne Holstege; Petra Mäkinen; Gaël Nicolas; Simon Mead; Michael Wagner; Alfredo Ramirez; Tuomas Rauramaa; Aarno Palotie; Rebecca Sims; Hilkka Soininen; John van Swieten; Julie Williams; Céline Bellenguez; Carla Gelle; Erwan Lambert; Marcos R. Costa; Julia TCW; Enrico Glaab; Anne-Marie Ayral; Florie Demiautte; Benjamin Grenier-Boley; Manon Muntaner; Delphine Eberlé; Séverine Deforges; Joel T. Haas; Devrim Kilinc; Christophe Mulle; Julien Chapuis; Mikko Hiltunen; Julie Dumont; Jean-Charles Lambert
Inflammatory stimulus enhances synaptic material uptake by adult APP microglia in a microfluidic neuron–microglia co-culture model

炎症刺激增强了成年APP小胶质细胞在微流控神经元-小胶质细胞共培养模型中的突触物质摄取。

Journal of Neuroinflammation
IF10.1
2026-02-190
OA
Dolores Siedlecki-Wullich; Anne-Marie Ayral; Lukas Iohan; Célia Lemeu; Valérie Buiche; Karine Blary; Julien Chapuis; Fanny Eysert; Delphine Beury; Myriam Delacre; David Hot; Takahiro Masuda; Klaus-Peter Knobeloch; Marco Prinz; Jean-Charles Lambert; Devrim Kilinc
Neuronal A2A receptor exacerbates synapse loss and memory deficits in APP/PS1 mice

神经元A2A受体加剧APP/PS1小鼠的突触丢失和记忆缺陷

BRAIN
IF11.7
2024-07-050
OAAI
Gomez-Murcia, Victoria; Launay, Agathe; Carvalho, Kevin; Burgard, Anaelle; Meriaux, Celine; Caillierez, Raphaelle; Eddarkaoui, Sabiha; Kilinc, Devrim; Siedlecki-Wullich, Dolores; Besegher, Melanie; Begard, Severine; Thiroux, Bryan; Jung, Matthieu; Nebie, Ouada; Wisztorski, Maxence; Deglon, Nicole; Montmasson, Claire; Bemelmans, Alexis-Pierre; Hamdane, Malika; Lebouvier, Thibaud; Vieau, Didier; Fournier, Isabelle; Buee, Luc; Levi, Sabine; Lopes, Luisa, V; Boutillier, Anne-Laurence; Faivre, Emilie; Blum, David
The Alzheimer's disease risk gene BIN1 regulates activity-dependent gene expression in human-induced glutamatergic neurons
MOLECULAR PSYCHIATRY
IF10.1
2024-03-222
OAAI
Saha, Orthis; Melo de Farias, Ana Raquel; Pelletier, Alexandre; Siedlecki-Wullich, Dolores; Landeira, Bruna Soares; Gadaut, Johanna; Carrier, Arnaud; Vreulx, Anais-Camille; Guyot, Karine; Shen, Yun; Bonnefond, Amelie; Amouyel, Philippe; Tcw, Julia; Kilinc, Devrim; Queiroz, Claudio Marcos; Delahaye, Fabien; Lambert, Jean-Charles; Costa, Marcos R.
Alzheimer's genetic risk factor FERMT2 (Kindlin-2) controls axonal growth and synaptic plasticity in an APP-dependent manner (Nov, 10.1038/s41380-020-00926-w, 2020)
MOLECULAR PSYCHIATRY
IF10.1
2021-01-042
OAAI
Eysert, Fanny; Coulon, Audrey; Boscher, Emmanuelle; Vreulx, Anais-Camille; Flaig, Amandine; Mendes, Tiago; Hughes, Sandrine; Grenier-Boley, Benjamin; Hanoulle, Xavier; Demiautte, Florie; Bauer, Charlotte; Marttinen, Mikael; Takalo, Mari; Amouyel, Philippe; Desai, Shruti; Pike, Ian; Hiltunen, Mikko; Checler, Frederic; Farinelli, Melissa; Delay, Charlotte; Malmanche, Nicolas; Hebert, Sebastien S.; Dumont, Julie; Kilinc, Devrim; Lambert, Jean-Charles; Chapuis, Julien
Alzheimer's genetic risk factor FERMT2 (Kindlin-2) controls axonal growth and synaptic plasticity in an APP-dependent manner

阿尔茨海默氏症的遗传危险因子FERMT2 (Kindlin-2) 以APP依赖性方式控制轴突生长和突触可塑性

MOLECULAR PSYCHIATRY
IF10.1
2020-11-0330
OAAI
Eysert, Fanny; Coulon, Audrey; Boscher, Emmanuelle; Flaig, Amandine; Mendes, Tiago; Hughes, Sandrine; Grenier-Boley, Benjamin; Hanoulle, Xavier; Demiautte, Florie; Bauer, Charlotte; Marttinen, Mikael; Takalo, Mari; Amouyel, Philippe; Desai, Shruti; Pike, Ian; Hiltunen, Mikko; Checler, Frederic; Farinelli, Melissa; Delay, Charlotte; Malmanche, Nicolas; Hebert, Sebastien S.; Dumont, Julie; Kilinc, Devrim; Lambert, Jean-Charles; Chapuis, Julien
BIN1 recovers tauopathy-induced long-term memory deficits in mice and interacts with Tau through Thr348 phosphorylation
ACTA NEUROPATHOLOGICA
IF9.3
2019-05-0738
OAAI
Sartori, Maxime; Mendes, Tiago; Desai, Shruti; Lasorsa, Alessia; Herledan, Adrien; Malmanche, Nicolas; Makinen, Petra; Marttinen, Mikael; Malki, Idir; Chapuis, Julien; Flaig, Amandine; Vreulx, Anais-Camille; Ciancia, Marion; Amouyel, Philippe; Leroux, Florence; Deprez, Benoit; Cantrelle, Francois-Xavier; Marechal, Damien; Pradier, Laurent; Hiltunen, Mikko; Landrieu, Isabelle; Kilinc, Devrim; Herault, Yann; Laporte, Jocelyn; Lambert, Jean-Charles

研究方向

暂未获取到该数据
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