David S. Waugh - Publications, H-index & Citations

David S. Waugh

national institutes of health (nih) - usa

52H指数

271论文数

9.6K被引数

收录论文 32

发表时间

P1′ specificity of the S219V/R203G mutant tobacco etch virus protease

PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

IF2.8

2024-04-26

OAAI

Golda, Maria; Hoffka, Gyula; Cherry, Scott; Tropea, Joseph E.; Lountos, George T.; Waugh, David S.; Wlodawer, Alexander; Tozser, Jozsef; Motyan, Janos Andras

Small molecule microarray identifies inhibitors of tyrosyl-DNA phosphodiesterase 1 that simultaneously access the catalytic pocket and two substrate binding sites

CHEMICAL SCIENCE

IF7.4

2021-01-01

OAAI

Zhao, Xue Zhi; Kiselev, Evgeny; Lountos, George T.; Wang, Wenjie; Tropea, Joseph E.; Needle, Danielle; Hilimire, Thomas A.; Schneekloth, John S., Jr.; Waugh, David S.; Pommier, Yves; Burke, Terrence R., Jr.

Identification of a ligand binding hot spot and structural motifs replicating aspects of tyrosyl-DNA phosphodiesterase I (TDP1) phosphoryl recognition by crystallographic fragment cocktail screening

NUCLEIC ACIDS RESEARCH

IF13.1

2019-06-14

OAAI

Lountos, George T.; Zhao, Xue Zhi; Kiselev, Evgeny; Tropea, Joseph E.; Needle, Danielle; Pommier, Yves; Burke, Terrence R., Jr.; Waugh, David S.

The molecular mechanism of dsRNA processing by a bacterial Dicer

NUCLEIC ACIDS RESEARCH

IF13.1

2019-03-27

OAAI

Jin, Lan; Song, He; Tropea, Joseph E.; Needle, Danielle; Waugh, David S.; Gu, Shuo; Ji, Xinhua

Discovery of small molecule inhibitors of MyD88-dependent signaling pathways using a computational screen (vol 5, 14246, 2015)

SCIENTIFIC REPORTS

IF3.9

2018-11-19

OAAI

Olson, Mark A.; Lee, Michael S.; Kissner, Teri L.; Alam, Shahabuddin; Waugh, David S.; Saikh, Kamal U.

Insights Into the Allosteric Inhibition of the SUMO E2 Enzyme Ubc9 对SUMO E2酶Ubc9的变构抑制的见解

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

IF16.9

2016-04-01

OAAI

Hewitt, William M.; Lountos, George T.; Zlotkowski, Katherine; Dahlhauser, Samuel D.; Saunders, Lindsey B.; Needle, Danielle; Tropea, Joseph E.; Zhan, Chendi; Wei, Guanghong; Ma, Buyong; Nussinov, Ruth; Waugh, David S.; Schneekloth, John S., Jr.

Discovery of small molecule inhibitors of MyD88-dependent signaling pathways using a computational screen

SCIENTIFIC REPORTS

IF3.9

2015-09-18

OAAI

Olson, Mark A.; Lee, Michael S.; Kissner, Teri L.; Alam, Shahabuddin; Waugh, David S.; Saikh, Kamal U.

BIOTECHNOLOGY AND BIOENGINEERING

IF3.6

2014-08-25

OAAI

Raran-Kurussi, Sreejith; Waugh, David S.

Structural enzymology and inhibition of the bi-functional folate pathway enzyme HPPK-DHPS from the biowarfare agent Francisella tularensis

FEBS JOURNAL

IF4.2

2014-07-23

OAAI

Shaw, Gary X.; Li, Yue; Shi, Genbin; Wu, Yan; Cherry, Scott; Needle, Danielle; Zhang, Di; Tropea, Joseph E.; Waugh, David S.; Yan, Honggao; Ji, Xinhua

RNase III: Genetics and Function; Structure and Mechanism

ANNUAL REVIEW OF GENETICS

IF0

2013-11-23

156

OAAI

Court, Donald L.; Gan, Jianhua; Liang, Yu-He; Shaw, Gary X.; Tropea, Joseph E.; Costantino, Nina; Waugh, David S.; Ji, Xinhua

Biomolecular Interactions of Small-molecule Inhibitors Affecting the YopH Protein Tyrosine Phosphatase

CHEMICAL BIOLOGY & DRUG DESIGN

IF3.3

2013-02-13

OAAI

Hogan, Megan; Bahta, Medhanit; Cherry, Scott; Lountos, George T.; Tropea, Joseph E.; Zhao, Bryan M.; Burke, Terrence R., Jr.; Waugh, David S.; Ulrich, Robert G.

Structural characterization of inhibitor complexes with checkpoint kinase 2 (Chk2), a drug target for cancer therapy

JOURNAL OF STRUCTURAL BIOLOGY

IF5.1

2011-12-01

OAAI

Lountos, George T.; Jobson, Andrew G.; Tropea, Joseph E.; Self, Christopher R.; Zhang, Guangtao; Pommier, Yves; Shoemaker, Robert H.; Waugh, David S.

X-ray structures of checkpoint kinase 2 in complex with inhibitors that target its gatekeeper-dependent hydrophobic pocket

FEBS LETTERS

IF3

2011-09-07

OAAI

Lountos, George T.; Jobson, Andrew G.; Tropea, Joseph E.; Self, Christopher R.; Zhang, Guangtao; Pommier, Yves; Shoemaker, Robert H.; Waugh, David S.

The Era GTPase recognizes the GAUCACCUCC sequence and binds helix 45 near the 3′ end of 16S rRNA

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2011-06-06

OAAI

Tu, Chao; Zhou, Xiaomei; Tarasov, Sergey G.; Tropea, Joseph E.; Austin, Brian P.; Waugh, David S.; Court, Donald L.; Ji, Xinhua

Utilization of Nitrophenylphosphates and Oxime-Based Ligation for the Development of Nanomolar Affinity Inhibitors of the Yersinia pestis Outer Protein H (YopH) Phosphatase

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2011-03-28

OAAI

Bahta, Medhanit; Lountos, George T.; Dyas, Beverly; Kim, Sung-Eun; Ulrich, Robert G.; Waugh, David S.; Burke, Terrence R., Jr.

Thermostable tag (TST) protein expression system: Engineering thermotolerant recombinant proteins and vaccines 耐热标签 (TST) 蛋白表达系统: 工程耐热重组蛋白和疫苗

JOURNAL OF BIOTECHNOLOGY

IF3.9

2011-02-01

OAAI

Luke, Jeremy M.; Carnes, Aaron E.; Sun, Ping; Hodgson, Clague P.; Waugh, David S.; Williams, James A.

Development of antiproliferative phenylmaleimides that activate the unfolded protein response

BIOORGANIC & MEDICINAL CHEMISTRY

IF3

2010-06-15

OAAI

Muus, Ulrike; Hose, Curtis; Yao, Wei; Kosakowska-Cholody, Teresa; Farnsworth, David; Dyba, Marzena; Lountos, George T.; Waugh, David S.; Monks, Anne; Burke, Terrence R., Jr.; Michejda, Christopher J.

Overproduction, Purification and Structure Determination of Human Dual Specificity Phosphatase 14

BIOPHYSICAL JOURNAL

IF3.1

2010-01-01

OAAI

Lountos, George; Tropea, Joseph; Cherry, Scott; Waugh, David

Cellular inhibition of Chk2 kinase and potentiation of camptothecins and radiation by the novel Chk2 inhibitor PV1019

MOLECULAR CANCER THERAPEUTICS

IF5.5

2009-12-01

PREAI

Jobson, Andrew; Lountos, George T.; Lorenzi, Philip; Connelly, John; Tropea, Joseph E.; Zoppoli, Gabriele; Kondapaka, Sudhir; Zhang, Guangtao; Caplen, Natasha J.; Cardellina, John H.; Yoo, Stephen S.; Monks, Anne; Self, Christopher; Waugh, David S.; Shoemaker, Robert H.; Pommier, Yves

Cellular Inhibition of Checkpoint Kinase 2 (Chk2) and Potentiation of Camptothecins and Radiation by the Novel Chk2 Inhibitor PV1019 [7-Nitro-1H-indole-2-carboxylic acid {4-[1-(guanidinohydrazone)-ethyl]-phenyl}-amide]

JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

IF3.8

2009-12-01

OAAI

Jobson, Andrew G.; Lountos, George T.; Lorenzi, Philip L.; Llamas, Jenny; Connelly, John; Cerna, David; Tropea, Joseph E.; Onda, Akikazu; Zoppoli, Gabriele; Kondapaka, Sudhir; Zhang, Guangtao; Caplen, Natasha J.; Cardellina, John H., II; Yoo, Stephen S.; Monks, Anne; Self, Christopher; Waugh, David S.; Shoemaker, Robert H.; Pommier, Yves

研究方向