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P

Pablo García-Losada

Eli Lilly
H指数:12
被引数:1,088

个人简介

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荣誉奖项

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Discovery and Early Clinical Development of LY3202626, a Low-Dose, CNS-Penetrant BACE Inhibitor
JOURNAL OF MEDICINAL CHEMISTRY
IF6.8
2021-06-0314
PREAI
McKinzie, David L.; Winneroski, Leonard L.; Green, Steven J.; Hembre, Erik J.; Erickson, Jon A.; Willis, Brian A.; Monk, Scott A.; Aluise, Christopher D.; Baker, Thomas K.; Lopez, Jose E.; Hendle, Jorg; Beck, James P.; Brier, Richard A.; Boggs, Leonard N.; Borders, Anthony R.; Cocke, Patrick J.; Garcia-Losada, Pablo; Lowe, Stephen L.; Mathes, Brian M.; May, Patrick C.; Porter, Warren J.; Stout, Stephanie L.; Timm, David E.; Watson, Brian M.; Yang, Zhixiang; Mergott, Dustin J.
Synthesis, Optimization, and Large-Scale Preparation of the Low Dose Central Nervous System-Penetrant BACE1 Inhibitor LY3202626 via a [3+2] Nitrone Cycloaddition
ORGANIC PROCESS RESEARCH & DEVELOPMENT
IF3.5
2020-01-298
PREAI
Garcia-Losada, Pablo; DeBaillie, Amy C.; de Diego, Jose Eugenio; Green, Steven J.; Hansen, Marvin M.; Jaramillo, Carlos; Johnson, Matt; Kaoudi, Talbi; Li, Jiuyuan; Lindsay-Scott, Peter J.; Mateos, Carlos; Mergott, Dustin James; Rincon, Juan A.; Rothhaar, Roger R.; Seibert, Kevin D.; Watson, Brian M.; Winneroski, Leonard L.; Gangula, Srinivas; Jing, Dajiang; Sun, Hao; Zhang, Lei; Frederick, Michael O.
Preparation and biological evaluation of BACE1 inhibitors: Leveraging trans-cyclopropyl moieties as ligand efficient conformational constraints
BIOORGANIC & MEDICINAL CHEMISTRY
IF3
2020-01-0113
PREAI
Winneroski, Leonard L.; Erickson, Jon A.; Green, Steven J.; Lopez, Jose E.; Stout, Stephanie L.; Porter, Warren J.; Timm, David E.; Audia, James E.; Barberis, Mario; Beck, James P.; Boggs, Leonard N.; Borders, Anthony R.; Boyer, Robert D.; Brier, Richard A.; Hembre, Erik J.; Hendle, Jorg; Garcia-Losada, Pablo; Minguez, Jose Miguel; Mathes, Brian M.; May, Patrick C.; Monk, Scott A.; Rankovic, Zoran; Shi, Yuan; Watson, Brian M.; Yang, Zhixiang; Mergott, Dustin J.
The Evolution of High-Throughput Experimentation in Pharmaceutical Development and Perspectives on the Future
ORGANIC PROCESS RESEARCH & DEVELOPMENT
IF3.5
2019-05-07340
OAAI
Mennen, Steven M.; Alhambra, Carolina; Allen, C. Liana; Barberis, Mario; Berritt, Simon; Brandt, Thomas A.; Campbell, Andrew D.; Castanon, Jesus; Cherney, Alan H.; Christensen, Melodie; Damon, David B.; Eugenio de Diego, J.; Garcia-Cerrada, Susana; Garcia-Losada, Pablo; Haro, Ruben; Janey, Jacob; Leitch, David C.; Li, Ling; Liu, Fangfan; Lobben, Paul C.; MacMillan, David W. C.; Magano, Javier; McInturff, Emma; Monfette, Sebastien; Post, Ronald J.; Schultz, Danielle; Sitter, Barbara J.; Stevens, Jason M.; Strambeanu, Julia I.; Twilton, Jack; Wang, Ke; Zajac, Matthew A.

研究方向

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J
Juan A. Rincón
H 指数:25论文数:58被引数:2,086
C
Carlos Mateos
H 指数:24论文数:106被引数:2,080
D
Dustin J. Mergott
H 指数:14论文数:45被引数:1,484
G
Graham R. Cumming
H 指数:12论文数:26被引数:678
M
Michael O. Frederick
H 指数:33论文数:89被引数:3,369
B
Brian M. Watson
H 指数:17论文数:69被引数:1,213
L
Leonard L. Winneroski
H 指数:19论文数:53被引数:1,491
M
María José Nieves‐Remacha
H 指数:10论文数:17被引数:716
T
Timothy Noël
H 指数:72论文数:431被引数:1.8万
L
Luca Capaldo
H 指数:25论文数:74被引数:4,306