Gottfried Otting - Publications, H-index & Citations

GoldfarbDaniella (Gottfried Otting)

the australian national university

81H指数

624论文数

2.4W被引数

收录论文 130

发表时间

Genetically Encoded Pentafluorophenylalanine Enables Quantitative Probing of Local Protein Malleability by 19F NMR 遗传编码的五氟苯丙氨酸通过19F NMR实现局部蛋白质可塑性的定量探查

Journal of the American Chemical Society

IF15.6

2026-08-05

PREAI

Nathan Paul; Adarshi P. Welegedara; Rebecca L. Frkic; Luca Macri; Toby R. C. Thompson; James L. Baber; Edan Habel; Elwy H. Abdelkader; Haocheng Qianzhu; Nicholas F. Chilton; Colin J. Jackson; Ad Bax; Thomas Huber; Gottfried Otting

Isosteric Engineering of Enzymes: Overcoming Activity–Stability Trade-Offs by Site-Selective CH → N Substitutions

Angewandte Chemie-International Edition

IF16.9

2026-07-27

OAAI

Elwy H. Abdelkader; Haocheng Qianzhu; Gottfried Otting; Thomas Huber

Publisher Correction: Artificial allosteric protein switches with machine-learning-designed receptors 出版者更正：具有机器学习设计受体的合成别构蛋白质开关

Nature Biotechnology

IF41.7

2026-07-20

OAAI

Zhong Guo; Oleh Smutok; Gyu Rie Lee; Zhenling Cui; Haocheng Qianzhu; Monika Kish; Cagla Ergun Ayva; Kejia Wu; Roxane Mutschler; Colin J. Jackson; Maria M. Fiorito; Andrew C. Warden; Oliver B. Smith; Alfredo Quijano-Rubio; Thomas Huber; Jonathan J. Phillips; Gottfried Otting; Evgeny Katz; David Baker; Kirill Alexandrov

Artificial allosteric protein switches with machine-learning-designed receptors 具有机器学习设计的受体的人工变构蛋白质开关

Nature Biotechnology

IF41.7

2026-04-15

OAAI

Zhong Guo; Oleh Smutok; Gyu Rie Lee; Zhenling Cui; Haocheng Qianzhu; Monika Kish; Cagla Ergun yva; Kejia Wu; Roxane Mutschler; Colin J. Jackson; Maria M. Fiorito; Andrew C. Warden; Oliver B. Smith; Alfredo Quijano-Rubio; Thomas Huber; Jonathan J. Phillips; Gottfried Otting; Evgeny Katz; David Baker; Kirill Alexandrov

Biosynthetic Lanthanide-Luminescent Mini-Proteins Using Genetic Code Expansion 利用遗传密码扩展合成具有镧系元素发光特性的微型蛋白质

Journal of the American Chemical Society

IF15.6

2026-03-31

PREAI

Edan Habel; Haocheng Qianzhu; Elwy H. Abdelkader; Nathan Paul; Gottfried Otting; Thomas Huber

19F-NMR spectroscopy of fluorinated isoleucine analogues in a protein 氟代异亮氨酸类似物在蛋白质中的19F-NMR光谱学

Journal of Biomolecular NMR

IF1.9

2026-02-17

OAAI

Welegedara, Adarshi P.; Tan, Yi Jiun; Borgini, Matteo; Wipf, Peter; Otting, Gottfried

Comparative evaluation of noncanonical amino acids as site-specific NMR probes for the complex of E. coli SSB with single-stranded DNA without isotope labelling 非规范氨基酸作为E. coli SSB与单链DNA复合物的位点特异性NMR探针的比较评估（无需同位素标记）

the febs journal

IF0

2026-02-10

OAAI

Sreelakshmi Mekkattu Tharayil; Haocheng Qianzhu; Elwy H. Abdelkader; Adarshi P. Welegedara; Josemon George; Christoph Nitsche; Thomas Huber; Gottfried Otting

Characterising Side Chain Conformations in Proteins Using 19F-ENDOR and New Fluorinated Amino Acid Spin Labels 使用19F-ENDOR和新氟代氨基酸自旋标记物表征蛋白质侧链构象

Chemistry – A European Journal

IF3.7

2025-10-31

PREAI

Martyna Judd; Elwy H. Abdelkader; Haocheng Qianzhu; Edan Habel; Caitlin Lindsay; Anthony Brancewicz; Thomas Huber; Gottfried Otting; Nicholas Cox

Measuring Nanometer Distances in Proteins and Rigid Rulers between 19F and Gd3+ by Integration of 19F-ENDOR Signal Intensities 通过19F-ENDOR信号强度的积分测量蛋白质和刚性标尺中纳米距离及19F与Gd3+之间的距离

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

IF15.6

2025-05-06

PREAI

Judd, Martyna; Qi, Mian; Abdelkader, Elwy H.; Qianzhu, Haocheng; Savitsky, Anton; Huber, Thomas; Harmer, Jeffrey R.; Godt, Adelheid; Otting, Gottfried

Genetic Encoding of Fluorinated Analogues of Phenylalanine for 19F NMR Spectroscopy: Detection of Conformational Heterogeneity in Flaviviral NS2B-NS3 Proteases 氟代苯丙氨酸类似物的遗传编码及其在19F核磁共振波谱学中的应用：鉴定黄病毒NS2B-NS3蛋白酶的构象异质性

ACS SENSORS

IF9.1

2025-04-01

PREAI

Qianzhu, HC; Tan, YJ; Abdelkader, EH; Huber, T; Otting, G

Rendering Proteins Fluorescent Inconspicuously: Genetically Encoded 4-Cyanotryptophan Conserves Their Structure and Enables the Detection of Ligand Binding Sites

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

IF16.9

2024-12-12

OAAI

Qianzhu, Haocheng; Abdelkader, Elwy H.; Welegedara, Adarshi P.; Habel, Edan; Paul, Nathan; Frkic, Rebecca L.; Jackson, Colin J.; Huber, Thomas; Otting, Gottfried

Ligand-induced conformational changes in protein molecules detected by sum-frequency generation

BIOPHYSICAL JOURNAL

IF3.1

2024-11-01

PREAI

Salafsky, Joshua; Johansson, Patrik K.; Abdelkader, Elwy; Otting, Gottfried

Genetic Encoding of Fluoro-l-tryptophans for Site-Specific Detection of Conformational Heterogeneity in Proteins by NMR Spectroscopy

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

IF15.6

2024-04-30

PREAI

Qianzhu, Haocheng; Abdelkader, Elwy H.; Otting, Gottfried; Huber, Thomas

Altering glycopeptide antibiotic biosynthesis through mutasynthesis allows incorporation of fluorinated phenylglycine residues

RSC CHEMICAL BIOLOGY

IF3.1

2024-01-01

OAAI

Voitsekhovskaia, Irina; Ho, Y. T. Candace; Klatt, Christoph; Mueller, Anna; Machell, Daniel L.; Tan, Yi Jiun; Triesman, Maxine; Bingel, Mara; Schittenhelm, Ralf B.; Tailhades, Julien; Kulik, Andreas; Maier, Martin E.; Otting, Gottfried; Wohlleben, Wolfgang; Schneider, Tanja; Cryle, Max; Stegmann, Evi

A lanthanide tag for a complementary set of pseudocontact shifts

CHEMICAL COMMUNICATIONS

IF4.2

2024-01-01

OAAI

Topping, Lydia; Welegedara, Adarshi P.; Judd, Martyna; Abdelkader, Elwy H.; Cox, Nicholas; Otting, Gottfried; Butler, Stephen J.

3D Structure of the Transient Intermediate of the Enzyme-Substrate Complex of Sortase A Reveals How Calcium Binding and Substrate Recognition Cooperate in Substrate Activation

ACS CATALYSIS

IF13.1

2023-08-18

PREAI

Chen, Jia-Liang; Wang, Xiao; Yang, Feng; Li, Bin; Otting, Gottfried; Su, Xun-Cheng

Probing Ligand Binding Sites on Large Proteins by Nuclear Magnetic Resonance Spectroscopy of Genetically Encoded Non-Canonical Amino Acids

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2023-03-15

PREAI

Ekanayake, Kasuni B.; Mahawaththa, Mithun C.; Qianzhu, Haocheng; Abdelkader, Elwy H.; George, Josemon; Ullrich, Sven; Murphy, Rhys B.; Fry, Sarah E.; Johansen-Leete, Jason; Payne, Richard J.; Nitsche, Christoph; Huber, Thomas; Otting, Gottfried

InOOH-mediated intergrown heterojunctions for enhanced photocatalytic Performance: Assembly and interfacial charge carrier transferring

CHEMICAL ENGINEERING JOURNAL

IF13.2

2022-08-01

OAAI

Nekouei, Farzin; Wen, Xiaoming; Zheng, Zhong; Sun, Qingbo; Lu, Teng; Orton, Henry; Kremer, Felipe; Nekouei, Shahram; Yuan, Tongwei; Abdelkader, Elwy H.; Liu, Borui; Tricoli, Antonio; Otting, Gottfried; Liu, Zongwen; Frankcombe, Terry; Liu, Yun

Genetic Encoding of Cyanopyridylalanine for In-Cell Protein Macrocyclization by the Nitrile-Aminothiol Click Reaction

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

IF16.9

2022-02-11

OAAI

Abdelkader, Elwy H.; Qianzhu, Haocheng; George, Josemon; Frkic, Rebecca L.; Jackson, Colin J.; Nitsche, Christoph; Otting, Gottfried; Huber, Thomas

Antiviral cyclic peptides targeting the main protease of SARS-CoV-2

CHEMICAL SCIENCE

IF7.4

2022-01-01

OAAI

Johansen-Leete, Jason; Ullrich, Sven; Fry, Sarah E.; Frkic, Rebecca; Bedding, Max J.; Aggarwal, Anupriya; Ashhurst, Anneliese S.; Ekanayake, Kasuni B.; Mahawaththa, Mithun C.; Sasi, Vishnu M.; Luedtke, Stephanie; Ford, Daniel J.; O'Donoghue, Anthony J.; Passioura, Toby; Larance, Mark; Otting, Gottfried; Turville, Stuart; Jackson, Colin J.; Nitsche, Christoph; Payne, Richard J.

研究方向