未登录 An Anti-β-Amyloid vaccine for treating cognitive deficits in a mouse model of down syndrome (vol 11, e0152471, 2016) 一种抗β-淀粉样蛋白疫苗用于治疗唐氏综合征小鼠模型中的认知缺陷（卷 11，e0152471，2016） Belichenko, Pavel V.; Madani, Rime; Rey-Bellet, Lorianne; Pihlgren, Maria; Becker, Ann; Plassard, Adeline; Vuillermot, Stephanie; Giriens, Valerie; Nosheny, Rachel L.; Kleschevnikov, Alexander M.; Valletta, Janice S.; Bengtsson, Sara K. S.; Linke, Gordon R.; Maloney, Michael T.; Hickman, David T.; Reis, Pedro; Granet, Anne; Mlaki, Dorin; Lopez-Deber, Maria Pilar; Do, Long; Singhal, Nishant; Masliah, Eliezer; Pearn, Matthew L.; Pfeifer, Andrea; Muhs, Andreas; Mobley, William C. 分享 收藏
Macrophage LRRK2 hyperactivity impairs autophagy and induces Paneth cell dysfunction Sun, Shengxiang; Hodel, Miki; Wang, Xiang; De Vicente, Javier; Haritunians, Talin; Debebe, Anketse; Hung, Chen-Ting; Ma, Changqing; Malique, Atika; Nguyen, Hoang N.; Agam, Maayan; Maloney, Michael T.; Goo, Marisa S.; Kluss, Jillian H.; Mishra, Richa; Frein, Jennifer; Foster, Amanda; Ballentine, Samuel; Pandey, Uday; Kern, Justin; Yang, Shaohong; Mengesha, Emebet; Balasubramanian, Iyshwarya; Arguello, Annie; Estrada, Anthony A.; Gao, Nan; Peter, Inga; Mcgovern, Dermot P. B.; Henry, Anastasia G.; Stappenbeck, Thaddeus S.; Liu, Ta-Chiang 分享 收藏
Rab12 is a regulator of LRRK2 and its activation by damaged lysosomes Rab12是LRRK2的调节因子，其被受损的溶酶体激活 Wang, Xiang; Bondar, Vitaliy V.; Davis, Oliver B.; Maloney, Michael T.; Agam, Maayan; Chin, Marcus Y.; Ho, Audrey Cheuk-Nga; Ghosh, Rajarshi; Leto, Dara E.; Joy, David; Calvert, Meredith E. K.; Lewcock, Joseph W.; Di Paolo, Gilbert; Thorne, Robert G.; Sweeney, Zachary K.; Henry, Anastasia G. 分享 收藏
Failure to Thrive: Impaired BDNF Transport along the Cortical-Striatal Axis in Mouse Q140 Neurons of Huntington's Disease 无法茁壮成长: 亨廷顿舞蹈病小鼠Q140神经元沿皮质-纹状体轴的BDNF运输受损 Maloney, Michael T.; Wang, Wei; Bhowmick, Sumana; Millan, Ivan; Kapur, Mridu; Herrera, Nicolas; Frost, Everett; Zhang, Elena Y.; Song, Scott; Wang, Melissa; Park, Amelia Bora; Yao, Annabelle Y.; Yang, Yanmin 分享 收藏
Preclinical and clinical evaluation of the LRRK2 inhibitor DNL201 for Parkinson's disease Jennings, Danna; Huntwork-Rodriguez, Sarah; Henry, Anastasia G.; Sasaki, Jennifer C.; Meisner, Rene; Diaz, Dolores; Solanoy, Hilda; Wang, Xiang; Negrou, Elvira; Bondar, Vitaliy V.; Ghosh, Rajarshi; Maloney, Michael T.; Propson, Nicholas E.; Zhu, Yuda; Maciuca, Romeo D.; Harris, Laura; Kay, Angela; LeWitt, Peter; King, T. Alex; Kern, Drew; Ellenbogen, Aaron; Goodman, Ira; Siderowf, Andrew; Aldred, Jason; Omidvar, Omid; Masoud, Shababa T.; Davis, Sonnet S.; Arguello, Annie; Estrada, Anthony A.; de Vicente, Javier; Sweeney, Zachary K.; Astarita, Giuseppe; Borin, Marie T.; Wong, Bradley K.; Wong, Harvey; Nguyen, Hoang; Scearce-Levie, Kimberly; Ho, Carole; Troyer, Matthew D. 分享 收藏
Understanding LRRK2 kinase activity in preclinical models and human subjects through quantitative analysis of LRRK2 and pT73 Rab10 Wang, Xiang; Negrou, Elvira; Maloney, Michael T.; Bondar, Vitaliy V.; Andrews, Shan V.; Montalban, Manuel; Llapashtica, Ceyda; Maciuca, Romeo; Hoang Nguyen; Solanoy, Hilda; Arguello, Annie; Przybyla, Laralynne; Moerke, Nathan J.; Huntwork-Rodriguez, Sarah; Henry, Anastasia G. 分享 收藏
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