Paolo Mascagni - Publications, H-index & Citations

Paolo Mascagni

University of Colorado System

43H指数

159论文数

6.7K被引数

收录论文 40

发表时间

Histone deacetylase activity governs diastolic dysfunction through a nongenomic mechanism

SCIENCE TRANSLATIONAL MEDICINE

IF14.6

2018-02-07

128

OAAI

Jeong, Mark Y.; Lin, Ying H.; Wennersten, Sara A.; Demos-Davies, Kimberly M.; Cavasin, Maria A.; Mahaffey, Jennifer H.; Monzani, Valmen; Saripalli, Chandrasekhar; Mascagni, Paolo; Reece, T. Brett; Ambardekar, Amrut V.; Granzier, Henk L.; Dinarello, Charles A.; McKinsey, Timothy A.

Specific Inhibition of Histone Deacetylase 8 Reduces Gene Expression and Production of Proinflammatory Cytokines in Vitro and in Vivo

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2015-01-01

OAAI

Li, Suzhao; Fossati, Gianluca; Marchetti, Carlo; Modena, Daniela; Pozzi, Pietro; Reznikov, Leonid L.; Moras, Maria Luisa; Azam, Tania; Abbate, Antonio; Mascagni, Paolo; Dinarello, Charles A.

Histone Deacetylase Inhibitors Modulate Interleukin 6-dependent CD4+ T Cell Polarization in Vitro and in Vivo

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2014-02-01

OAAI

Glauben, Rainer; Sonnenberg, Elena; Wetzel, Martin; Mascagni, Paolo; Siegmund, Britta

Lysine deacetylase inhibition prevents diabetes by chromatin-independent immunoregulation and β-cell protection

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2014-01-06

OAAI

Christensen, Dan Ploug; Gysemans, Conny; Lundh, Morten; Dahllof, Mattias Salling; Noesgaard, Daniel; Schmidt, Soren Fisker; Mandrup, Susanne; Birkbak, Nikolai; Workman, Christopher T.; Piemonti, Lorenzo; Blaabjerg, Lykke; Monzani, Valmen; Fossati, Gianluca; Mascagni, Paolo; Paraskevas, Steven; Aikin, Reid A.; Billestrup, Nils; Grunnet, Lars Groth; Dinarello, Charles A.; Mathieu, Chantal; Mandrup-Poulsen, Thomas

Preclinical Studies in the mdx Mouse Model of Duchenne Muscular Dystrophy with the Histone Deacetylase Inhibitor Givinostat

MOLECULAR MEDICINE

IF6.4

2013-03-27

123

OAAI

Consalvi, Silvia; Mozzetta, Chiara; Bettica, Paolo; Germani, Massimiliano; Fiorentini, Francesco; Del Bene, Francesca; Rocchetti, Maurizio; Leoni, Flavio; Monzani, Valmen; Mascagni, Paolo; Puri, Pier Lorenzo; Saccone, Valentina

Histone deacetylases 1 and 3 but not 2 mediate cytokine-induced beta cell apoptosis in INS-1 cells and dispersed primary islets from rats and are differentially regulated in the islets of type 1 diabetic children

DIABETOLOGIA

IF10.2

2012-07-07

OAAI

Lundh, M.; Christensen, D. P.; Nielsen, M. Damgaard; Richardson, S. J.; Dahllof, M. S.; Skovgaard, T.; Berthelsen, J.; Dinarello, C. A.; Stevenazzi, A.; Mascagni, P.; Grunnet, L. G.; Morgan, N. G.; Mandrup-Poulsen, T.

Functional consequences of inhibiting exocytosis of Weibel-Palade bodies in acute renal ischemia

AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY

IF3.4

2012-03-15

OAAI

Yasuda, Kaoru; Vasko, Radovan; Hayek, Peter; Ratliff, Brian; Bicer, Hasan; Mares, Jonathan; Maruyama, Shoichi; Bertuglia, Silvia; Mascagni, Paolo; Goligorsky, Michael S.

Histone Deacetylase Inhibitors for Treating a Spectrum of Diseases Not Related to Cancer

MOLECULAR MEDICINE

IF6.4

2011-05-05

153

OAAI

Dinarello, Charles A.; Fossati, Gianluca; Mascagni, Paolo

Pharmacokinetics, Safety and Inducible Cytokine Responses during a Phase 1 Trial of the Oral Histone Deacetylase Inhibitor ITF2357 (Givinostat)

MOLECULAR MEDICINE

IF6.4

2011-02-22

104

OAAI

Furlan, Antonio; Monzani, Valmen; Reznikov, Leonid L.; Leoni, Flavio; Fossati, Gianluca; Modena, Daniela; Mascagni, Paolo; Dinarello, Charles A.

Inhibition of HDAC Activity by ITF2357 Ameliorates Joint Inflammation and Prevents Cartilage and Bone Destruction in Experimental Arthritis

MOLECULAR MEDICINE

IF6.4

2011-02-11

OAAI

Joosten, Leo A. B.; Leoni, Flavio; Meghji, Sajeda; Mascagni, Paolo

The Oral Histone Deacetylase Inhibitor ITF2357 Reduces Cytokines and Protects Islet β Cells In Vivo and In Vitro

MOLECULAR MEDICINE

IF6.4

2011-01-03

108

OAAI

Lewis, Eli C.; Blaabjerg, Lykke; Storling, Joachim; Ronn, Sif G.; Mascagni, Paolo; Dinarello, Charles A.; Mandrup-Poulsen, Thomas

Lysine deacetylases are produced in pancreatic beta cells and are differentially regulated by proinflammatory cytokines

DIABETOLOGIA

IF10.2

2010-09-28

OAAI

Lundh, M.; Christensen, D. P.; Rasmussen, D. N.; Mascagni, P.; Dinarello, C. A.; Billestrup, N.; Grunnet, L. G.; Mandrup-Poulsen, T.

Histone deacetylase (HDAC) inhibitors reduce the glial inflammatory response in vitro and in vivo

NEUROBIOLOGY OF DISEASE

IF5.6

2009-11-01

121

PREAI

Faraco, Giuseppe; Pittelli, Maria; Cavone, Leonardo; Fossati, Silvia; Porcu, Marco; Mascagni, Paolo; Fossati, Gianluca; Moroni, Flavio; Chiarugi, Alberto

The oral histone deacetylase inhibitor ITF2357 reduces cytokine production, cytokine activities and protects islet β-cells in vivo and in vitro

CYTOKINE

IF3.7

2009-10-01

PREAI

Lewis, Eli C.; Blaabjerg, Lykke; Storling, Joachim; Ronn, Sif G.; Mascagni, Paolo; Dinarello, Charles A.; Mandrup-Poulsen, Thomas

The histone deacetylase inhibitor ITF2357 decreases surface CXCR4 and CCR5 expression in CD4+ T-cells and monocytes and induces latent HIV-1 expression in vitro

CYTOKINE

IF3.7

2009-10-01

PREAI

Matalon, Shay; Palmer, Brent E.; Nold, Marcel F.; Furlan, Antonio; Fossati, Gianluca; Mascagni, Paolo; Dinarello, Charles A.

Histone deacetylase inhibitor ITF2357 is neuroprotective, improves functional recovery, and induces glial apoptosis following experimental traumatic brain injury

FASEB JOURNAL

IF4.2

2009-09-01

OAAI

Shein, Na'ama A.; Grigoriadis, Nikolaos; Alexandrovich, Alexander G.; Simeonidou, Constantina; Lourbopoulos, Athanasios; Polyzoidou, Eleni; Trembovler, Victoria; Mascagni, Paolo; Dinarello, Charles A.; Shohami, Esther

Histone deacetylase inhibition modulates indoleamine 2,3-dioxygenase-dependent DC functions and regulates experimental graft-versus-host disease in mice

JOURNAL OF CLINICAL INVESTIGATION

IF13.6

2008-06-01

257

OAAI

Reddy, Pavan; Sun, Yaping; Toubai, Tomomi; Duran-Struuck, Raimon; Clouthier, Shawn G.; Weisiger, Elizabeth; Maeda, Yoshinobu; Tawara, Isao; Krijanovski, Oleg; Gatza, Erin; Liu, Chen; Malter, Chelsea; Mascagni, Paolo; Dinarello, Charles A.; Ferrara, James L. M.

ITF1697, a stable Lys-Pro-containing peptide, inhibits Weibel-Palade body exocytosis induced by ischemia/reperfusion and pressure elevation

MOLECULAR MEDICINE

IF6.4

2007-11-01

OAAI

Bertuglia, Silvia; Ichimura, Hideo; Fossati, Gianluca; Parthasarathi, Kaushik; Leoni, Flavio; Modena, Daniela; Cremonesi, Piero; Bhattacharya, Jahar; Mascagni, Paolo

Selective anti-leukaemic activity of low-dose histone deacetylase inhibitor ITF2357 on AML1/ETO-positive cells

ONCOGENE

IF7.3

2007-09-24

PREAI

Barbetti, V.; Gozzini, A.; Rovida, E.; Morandi, A.; Spinelli, E.; Fossati, G.; Mascagni, P.; Luebbert, M.; Dello Sbarba, P.; Santini, V.

The histone deacetylase inhibitor ITF2357 has anti-leukemic activity in vitro and in vivo and inhibits IL-6 and VEGF production by stromal cells

LEUKEMIA

IF13.4

2007-07-19

102

PREAI

Golay, J.; Cuppini, L.; Leoni, F.; Mico, C.; Barbui, V.; Domenghini, M.; Lombardi, L.; Neri, A.; Barbui, A. M.; Salvi, A.; Pozzi, P.; Porro, G.; Pagani, P.; Fossati, G.; Mascagni, P.; Introna, M.; Rambaldi, A.

研究方向