Pedro D’Orléans-Juste - Publications, H-index & Citations

Pedro D’Orléans-Juste

University of Sherbrooke

49H指数

285论文数

9.0K被引数

收录论文 67

发表时间

Recombinant chymase inhibits fibrinolysis induced by endogenous plasmin in clotted human blood 重组胰蛋白酶抑制剂可抑制人凝血块中内源性纤溶酶诱导的纤溶作用

FRONTIERS IN IMMUNOLOGY

IF5.9

2025-04-17

OAAI

Vincent, Laurence; Lapointe, Catherine; Mcdonald, Patrick P.; Rammos, Christos; Rassaf, Tienush; Koellnberger, Maria; Tinel, Hanna; Heitmeier, Stefan; D'Orleans-Juste, Pedro

Discovery and Preclinical Characterization of Fulacimstat (BAY 1142524), a Potent and Selective Chymase Inhibitor As a New Profibrinolytic Approach for Safe Thrombus Resolution

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2024-11-14

OAAI

Fuerstner, Chantal; Ackerstaff, Jens; Meier, Heinrich; Straub, Alexander; Mittendorf, Joachim; Schamberger, Jens; Schaefer, Martina; Boerngen, Kirsten; Joerissen, Hannah; Zubov, Dmitry; Zimmermann, Katja; Tersteegen, Adrian; Geiss, Volker; Hartmann, Elke; Albrecht-Kuepper, Barbara; D'Orleans-Juste, Pedro; Lapointe, Catherine; Vincent, Laurence; Heitmeier, Stefan; Tinel, Hanna

Enhanced Extraction of Blood and Tissue Time-Activity Curves in Cardiac Mouse FDG PET Imaging by Means of Constrained Nonnegative Matrix Factorization

INTERNATIONAL JOURNAL OF BIOMEDICAL IMAGING

IF1.3

2023-06-15

OAAI

Sarrhini, Otman; D'Orleans-Juste, Pedro; Rousseau, Jacques A. A.; Beaudoin, Jean-Francois; Lecomte, Roger

Loss of Endothelial Furin Leads to Cardiac Malformation and Early Postnatal Death 内皮弗林蛋白酶的丧失导致心脏畸形和出生后早期死亡

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-20

OAAI

Kim, WooJin; Essalmani, Rachid; Szumska, Dorota; Creemers, John W. M.; Roebroek, Anton J. M.; D'Orleans-Juste, Pedro; Bhattacharya, Shoumo; Seidah, Nabil G.; Prat, Annik

Chymase Inhibition Resolves and Prevents Deep Vein Thrombosis Without Increasing Bleeding Time in the Mouse Model

JOURNAL OF THE AMERICAN HEART ASSOCIATION

IF5.3

2023-02-21

OAAI

Lapointe, Catherine; Vincent, Laurence; Giguere, Hugo; Auger-Messier, Mannix; Schwertani, Adel; Jin, Denan; Takai, Shinji; Pejler, Gunnar; Sirois, Martin G. G.; Tinel, Hanna; Heitmeier, Stefan; D'Orleans-Juste, Pedro

Mast Cell Degranulation Increases Mouse Mast Cell Protease 4-Dependent Vasopressor Responses to Big Endothelin-1 But Not Angiotensin

JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

IF3.8

2021-02-01

OAAI

Vincent, Laurence; Lapointe, Catherine; Lo, Modou; Gagnon, Hugo; Pejler, Gunnar; Takai, Shinji; Day, Robert; D'Orleans-Juste, Pedro

Experimental Autoimmune Encephalomyelitis Potentiates Mouse Mast Cell Protease 4-Dependent Pressor Responses to Centrally or Systemically Administered Big Endothelin-1

JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

IF3.8

2019-09-01

OAAI

Desbiens, Louisane; Lapointe, Catherine; Gendron, Louis; Gharagozloo, Marjan; Vincent, Laurence; Pejler, Gunnar; Gris, Denis; D'Orleans-Juste, Pedro

ALTERED INHIBITION OF PLATELET AGGREGATION IN HYPERCHOLEROLEMIA IN MICE AND HUMANS

ATHEROSCLEROSIS

IF5.7

2019-08-01

PREAI

Houde, M.; Carrier, E.; Grandbois, M.; Bkaily, G.; Warner, T. D.; Korporaal, S. J. A.; Van Eck, M.; D'Orleans-Juste, P.

Endothelins in inflammatory neurological diseases

PHARMACOLOGY & THERAPEUTICS

IF12.5

2019-02-01

OAAI

D'Orleans-Juste, Pedro; Ndunge, Oscar B. Akide; Desbiens, Louisane; Tanowitz, Herbert B.; Desruisseaux, Mahalia S.

Endothelin receptor antagonist macitentan or deletion of mouse mast cell protease 4 delays lesion development in atherosclerotic mice

LIFE SCIENCES

IF5.1

2016-08-01

PREAI

Houde, Martin; Desbiens, Louisane; Schwertani, Adel; Pejler, Gunnar; Iglarz, Marc; D'Orleans-Juste, Pedro

Significant Contribution of Mouse Mast Cell Protease 4 in Early Phases of Experimental Autoimmune Encephalomyelitis

MEDIATORS OF INFLAMMATION

IF4.2

2016-01-01

OAAI

Desbiens, Louisane; Lapointe, Catherine; Gharagozloo, Marjan; Mahmoud, Shaimaa; Pejler, Gunnar; Gris, Denis; D'Orleans-Juste, Pedro

Contribution of oxidative stress and prostanoids in endothelial dysfunction induced by chronic fluoxetine treatment

VASCULAR PHARMACOLOGY

IF3.5

2015-10-01

PREAI

Simplicio, Janaina A.; Resstel, Leonardo B.; Tirapelli, Daniela P. C.; D'Orleans-Juste, Pedro; Tirapelli, Carlos R.

Chymase inhibitor-sensitive synthesis of endothelin-1 (1-31) by recombinant mouse mast cell protease 4 and human chymase

BIOCHEMICAL PHARMACOLOGY

IF5.6

2015-03-01

PREAI

Semaan, Walid; Desbiens, Louisane; Houde, Martin; Labonte, Julie; Gagnon, Hugo; Yamamoto, Daisuke; Takai, Shinji; Laidlaw, Tanya; Bkaily, Ghassan; Schwertani, Fadel; Pejler, Gunnar; Levesque, Christine; Desjardins, Roxane; Day, Robert; D'Orleans-Juste, Pedro

Are Sildenafil Derivatives Useful Even in Unborn Males?

HYPERTENSION

IF8.2

2013-10-01

OAAI

D'Orleans-Juste, Pedro; Houde, Martin; Semaan, Walid

High salt-induced hypertension in B2 knockout mice is corrected by the ETA antagonist, A127722

BRITISH JOURNAL OF PHARMACOLOGY

IF7.7

2013-08-27

OAAI

Brochu, I.; Houde, M.; Desbiens, L.; Simard, E.; Gobeil, F.; Semaan, W.; Bkaily, G.; D'Orleans-Juste, P.

Pivotal Role of Mouse Mast Cell Protease 4 in the Conversion and Pressor Properties of Big-Endothelin-1

JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

IF3.8

2013-07-01

OAAI

Houde, Martin; Jamain, Marc-David; Labonte, Julie; Desbiens, Louisane; Pejler, Gunnar; Gurish, Michael; Takai, Shinji; D'Orleans-Juste, Pedro

8-BuS-ATP derivatives as specific NTPDase1 inhibitors

BRITISH JOURNAL OF PHARMACOLOGY

IF7.7

2013-04-12

OAAI

Lecka, Joanna; Gillerman, Irina; Fausther, Michel; Salem, Mabrouka; Munkonda, Mercedes N.; Brosseau, Jean-Philippe; Cadot, Christine; Martin-Satue, Mireia; d'Orleans-Juste, Pedro; Rousseau, Eric; Poirier, Donald; Kuenzli, Beat; Fischer, Bilha; Sevigny, Jean

Genetic and Pharmacological Manipulation of Urotensin II Ameliorate the Metabolic and Atherosclerosis Sequalae in Mice

ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

IF7.4

2012-08-01

OAAI

You, Zhipeng; Genest, Jacques, Jr.; Barrette, Pierre-Olivier; Hafiane, Anouar; Behm, David J.; D'Orleans-Juste, Pedro; Schwertani, Adel Giaid

Disruption of Proprotein Convertase 1/3 (PC1/3) Expression in Mice Causes Innate Immune Defects and Uncontrolled Cytokine Secretion

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2012-04-01

OAAI

Refaie, Sarah; Gagnon, Sandra; Gagnon, Hugo; Desjardins, Roxane; D'Anjou, Francois; D'Orleans-Juste, Pedro; Zhu, Xiaorong; Steiner, Donald F.; Seidah, Nabil G.; Lazure, Claude; Salzet, Michel; Day, Robert

Potential Role of Endothelin-1 in Pulmonary Fibrosis From the Bench to the Clinic

AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

IF5.3

2010-01-01

PREAI

Ross, Bryan; D'Orleans-Juste, Pedro; Giaid, Adel

研究方向