未登录 Inhibitory Fc-Gamma IIb Receptor Signaling Induced by Multivalent IgG-Fc Is Dependent on Sialylation Beneduce, Christopher; Nguyen, Stephanie; Washburn, Nathaniel; Schaeck, John; Meccariello, Robin; Holte, Kimberly; Ortiz, Daniel; Manning, Anthony M.; Bosques, Carlos J.; Kurtagic, Elma 分享 收藏
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Improved Fc-mediated effector functions by an anti-CTLA-4 multivalent Fc agent Rutitzky, Laura; Ortiz, Daniel F.; Lansing, Jonathan C.; Brown, Julia; Paquette, Joseph; Garofalo, Kevin; D'Alessandro, Josephine; Bhatnagar, Naveen; Hains, Maurice; Gupta, Abhinav; Lee, Stan; Zouaoui, Radouane; Wang, Jason; Schaeck, John; Marchese, Salvatore; Meccariello, Robin; Washburn, Nathaniel; Holte, Kimberly; Bosques, Carlos J.; Manning, Anthony M. 分享 收藏
Circulating Markers of Inflammation Persist in Children and Adults With Giant Aneurysms After Kawasaki Disease Lech, Miroslaw; Guess, Jamey; Duffner, Jay; Oyamada, Jun; Shimizu, Chisato; Hoshino, Shinsuke; Farutin, Victor; Bulik, Dorota A.; Gutierrez, Bryan; Sarvaiya, Hetal; Kapoor, Bulbul; Koppes, Laura; Saldova, Radka; Stockmann, Henning; Albrecht, Simone; McManus, Ciara; Rudd, Pauline M.; Kaundinya, Ganesh, V; Manning, Anthony M.; Bosques, Carlos J.; Kahn, Andrew M.; Daniels, Lori B.; Gordon, John B.; Tremoulet, Adriana H.; Capila, Ishan; Gunay, Nur Sibel; Ling, Leona E.; Burns, Jane C. 分享 收藏
Characterization of Endogenous Human FcγRIII by Mass Spectrometry Reveals Site, Allele and Sequence Specific Glycosylation Washburn, Nathaniel; Meccariello, Robin; Duffner, Jay; Getchell, Kristen; Holte, Kimberly; Prod'homme, Thomas; Srinivasan, Karunya; Prenovitz, Robert; Lansing, Jonathan; Capila, Ishan; Kaundinya, Ganesh; Manning, Anthony M.; Bosques, Carlos J. 分享 收藏
M281, an Anti-FcRn Antibody: Pharmacodynamics, Pharmacokinetics, and Safety Across the Full Range of IgG Reduction in a First-in-Human Study Ling, Leona E.; Hillson, Jan L.; Tiessen, Renger G.; Bosje, Tjerk; van Iersel, Mattheus Paulus; Nix, Darrell J.; Markowitz, Lynn; Cilfone, Nicholas A.; Duffner, Jay; Streisand, James B.; Manning, Anthony M.; Arroyo, Santiago 分享 收藏
Elucidating the interplay between IgG-Fc valency and FcγR activation for the design of immune complex inhibitors Ortiz, Daniel F.; Lansing, Jonathan C.; Rutitzky, Laura; Kurtagic, Elma; Prod'homme, Thomas; Choudhury, Amit; Washburn, Nathaniel; Bhatnagar, Naveen; Beneduce, Christopher; Holte, Kimberly; Prenovitz, Robert; Child, Matthew; Killough, Jason; Tyler, Steven; Brown, Julia; Nguyen, Stephanie; Schwab, Inessa; Hains, Maurice; Meccariello, Robin; Markowitz, Lynn; Wang, Jing; Zouaoui, Radouane; Simpson, Allison; Schultes, Birgit; Capila, Ishan; Ling, Leona; Nimmerjahn, Falk; Manning, Anthony M.; Bosques, Carlos J. 分享 收藏
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HIGH-RESOLUTION, INTEGRATED MOLECULAR PROFILING REVEALS PERSISTENT INFLAMMATION IN KAWASAKI DISEASE PATIENTS WITH CORONARY ARTERY ANEURYSMS Ling, L. E.; Bulik, D.; Duffner, J.; Shimizu, C.; Sarvaiya, H.; Kapoor, B.; Brown, J.; Markowitz, L.; Arevalo, E.; Schultes, B.; Capila, I.; Saldova, R.; Stockmann, H.; Albrecht, S.; McManus, C.; Rudd, P. M.; Kaudinya, G. V.; Manning, A. M.; Tremoulet, A. H.; Bosques, C.; Burns, J. C. 分享 收藏
SELECTIVE IMMUNOMODULATORS OF FC-GAMMA RECEPTORS (SIFS) TO INHIBIT AUTOANTIBODY-MEDIATED PATHOLOGY Basques, C. J.; Lansing, J.; Ortiz, D.; Rutitzky, L.; Washburn, N.; Bhatnagar, N.; Kurtagic, E.; Choudhury, A.; Prod'homme, T.; Schultes, B.; Roy, S.; Kaundinya, G. V.; Manning, A. M. 分享 收藏
TARGETING THE NEONATAL FC RECEPTOR (FCRN) TO MEDIATE AUTOANTIBODY CLEARANCE IN IGG-DRIVEN AUTOIMMUNE DISEASE Ling, L. E.; Roy, S.; Meador, J.; Kehry, M.; Mekala, D.; Tyler, S.; Bulik, D.; Choudhury, A.; Markowitz, L.; Schultes, B.; Avery, W.; Parge, V.; Cochran, E.; King, D.; Kaundinya, G. V.; Manning, A. M. 分享 收藏
Controlled tetra-Fc sialylation of IVIg results in a drug candidate with consistent enhanced anti-inflammatory activity Washburn, Nathaniel; Schwab, Inessa; Ortiz, Daniel; Bhatnagar, Naveen; Lansing, Jonathan C.; Medeiros, Amy; Tyler, Steven; Mekala, Divya; Cochran, Edward; Sarvaiya, Hetal; Garofalo, Kevin; Meccariello, Robin; Meador, James W., III; Rutitzky, Laura; Schultes, Birgit C.; Ling, Leona; Avery, William; Nimmerjahn, Falk; Manning, Anthony M.; Kaundinya, Ganesh V.; Bosques, Carlos J. 分享 收藏
EC144, a Synthetic Inhibitor of Heat Shock Protein 90, Blocks Innate and Adaptive Immune Responses in Models of Inflammation and Autoimmunity Yun, Theodore J.; Harning, Erin K.; Giza, Keith; Rabah, Dania; Li, Ping; Arndt, Joseph W.; Luchetti, David; Biamonte, Marco A.; Shi, Jiandong; Lundgren, Karen; Manning, Anthony; Kehry, Marilyn R. 分享 收藏
Pamapimod, a Novel p38 Mitogen-Activated Protein Kinase Inhibitor: Preclinical Analysis of Efficacy and Selectivity Hill, Ronald J.; Dabbagh, Karim; Phippard, Deborah; Li, Ching; Suttmann, Rebecca T.; Welch, Mary; Papp, Eva; Song, Kyung W.; Chang, Kung-Ching; Leaffer, David; Kim, Yong-Nam; Roberts, Richard T.; Zabka, Tanja S.; Aud, Dee; Dal Porto, Joseph; Manning, Anthony M.; Peng, Stanford L.; Goldstein, David M.; Wong, Brian R. 分享 收藏
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Fanconi anemia protein complex is a novel target of the IKK signalsome Otsuki, T; Young, DB; Sasaki, DT; Pando, MP; Li, JW; Manning, A; Hoekstra, M; Hoatlin, ME; Mercurio, F; Liu, JM 分享 收藏
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