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In vivo screen of Plasmodium targets for mosquito-based malaria control 基于蚊媒疟疾控制的疟原虫体内靶点筛选 Probst, Alexandra S.; Paton, Douglas G.; Appetecchia, Federico; Bopp, Selina; Adams, Kelsey L.; Rinvee, Tasneem A.; Pou, Sovitj; Winter, Rolf; Du, Esrah W.; Yahiya, Sabrina; Vidoudez, Charles; Singh, Naresh; Rodrigues, Janneth; Castaneda-Casado, Pablo; Tammaro, Chiara; Chen, Daisy; Godinez-Macias, Karla P.; Jaramillo, Jasmine L.; Poce, Giovanna; Rubal, Michael J.; Nilsen, Aaron; Winzeler, Elizabeth A.; Baum, Jake; Burrows, Jeremy N.; Riscoe, Michael K.; Wirth, Dyann F.; Catteruccia, Flaminia 分享 收藏
MalKinID: A classification model for identifying malaria parasite genealogical relationships using identity-by-descent Wong, Wesley; Wang, Lea; Schaffner, Stephen F.; Li, Xue; Cheeseman, Ian; Anderson, Timothy J. C.; Vaughan, Ashley; Ferdig, Michael; Volkman, Sarah K.; Hartl, Daniel L.; Wirth, Dyann F. 分享 收藏
Genotypic analysis of RTS,S/AS01E malaria vaccine efficacy against parasite infection as a function of dosage regimen and baseline malaria infection status in children aged 5-17 months in Ghana and Kenya: a longitudinal phase 2b randomised controlled trial Juraska, Michal; Early, Angela M.; Li, Li; Schaffner, Stephen F.; Lievens, Marc; Khorgade, Akanksha; Simpkins, Brian; Hejazi, Nima S.; Benkeser, David; Wang, Qi; Mercer, Laina; Adjei, Samuel; Agbenyega, Tsiri; Anderson, Scott; Ansong, Daniel; Bii, Dennis K.; Buabeng, Patrick B. Y.; English, Sean; Fitzgerald, Nicholas; Grimsby, Jonna; Kariuki, Simon K.; Otieno, Kephas; Roman, Francois; Samuels, Aaron M.; Westercamp, Nelli; Ockenhouse, Christian F.; Ofori-Anyinam, Opokua; Lee, Cynthia K.; Macinnis, Bronwyn L.; Wirth, Dyann F.; Gilbert, Peter B.; Neafsey, Daniel E. 分享 收藏
Malaria surveillance reveals parasite relatedness, signatures of selection, and correlates of transmission across Senegal Schaffner, Stephen F.; Badiane, Aida; Khorgade, Akanksha; Ndiop, Medoune; Gomis, Jules; Wong, Wesley; Ndiaye, Yaye Die; Diedhiou, Younouss; Thwing, Julie; Seck, Mame Cheikh; Early, Angela; Sy, Mouhamad; Deme, Awa; Diallo, Mamadou Alpha; Sy, Ngayo; Sene, Aita; Ndiaye, Tolla; Sow, Djiby; Dieye, Baba; Ndiaye, Ibrahima Mbaye; Gaye, Amy; Ndiaye, Aliou; Battle, Katherine E.; Proctor, Joshua L.; Bever, Caitlin; Fall, Fatou Ba; Diallo, Ibrahima; Gaye, Seynabou; Sene, Doudou; Hartl, Daniel L.; Wirth, Dyann F.; Macinnis, Bronwyn; Ndiaye, Daouda; Volkman, Sarah K. 分享 收藏
Diverse evolutionary pathways challenge the use of collateral sensitivity as a strategy to suppress resistance Mandt, Rebecca E. K.; Luth, Madeline R.; Tye, Mark A.; Mazitschek, Ralph; Ottilie, Sabine; Winzeler, Elizabeth A.; Lafuente-Monasterio, Maria Jose; Gamo, Francisco Javier; Wirth, Dyann F.; Lukens, Amanda K. 分享 收藏
Potent acyl-CoA synthetase 10 inhibitors kill Plasmodium falciparum by disrupting triglyceride formation Bopp, Selina; Pasaje, Charisse Flerida A.; Summers, Robert L.; Magistrado-Coxen, Pamela; Schindler, Kyra A.; Corpas-Lopez, Victoriano; Yeo, Tomas; Mok, Sachel; Dey, Sumanta; Smick, Sebastian; Nasamu, Armiyaw S.; Demas, Allison R.; Milne, Rachel; Wiedemar, Natalie; Corey, Victoria; Gomez-Lorenzo, Maria De Gracia; Franco, Virginia; Early, Angela M.; Lukens, Amanda K.; Milner, Danny; Furtado, Jeremy; Gamo, Francisco-Javier; Winzeler, Elizabeth A.; Volkman, Sarah K.; Duffey, Maelle; Laleu, Benoit; Fidock, David A.; Wyllie, Susan; Niles, Jacquin C.; Wirth, Dyann F. 分享 收藏
RH: a genetic metric for measuring intrahost Plasmodium falciparum relatedness and distinguishing cotransmission from superinfection Wong, Wesley; Volkman, Sarah; Daniels, Rachel; Schaffner, Stephen; Sy, Mouhamad; Ndiaye, Yaye Die; Badiane, Aida S.; Deme, Awa B.; Diallo, Mamadou Alpha; Gomis, Jules; Sy, Ngayo; Ndiaye, Daouda; Wirth, Dyann F.; Hartl, Daniel L. 分享 收藏
Elucidating the path to Plasmodium prolyl-tRNA synthetase inhibitors that overcome halofuginone resistance 阐明克服卤夫酮抗性的疟原虫proliyl-trna合成酶抑制剂的途径 Tye, Mark A.; Payne, N. Connor; Johansson, Catrine; Singh, Kritika; Santos, Sofia A.; Fagbami, Lola; Pant, Akansha; Sylvester, Kayla; Luth, Madeline R.; Marques, Sofia; Whitman, Malcolm; Mota, Maria M.; Winzeler, Elizabeth A.; Lukens, Amanda K.; Derbyshire, Emily R.; Oppermann, Udo; Wirth, Dyann F.; Mazitschek, Ralph 分享 收藏
Using an antimalarial in mosquitoes overcomes Anopheles and Plasmodium resistance to malaria control strategies Paton, Douglas G.; Probst, Alexandra S.; Ma, Erica; Adams, Kelsey L.; Shaw, W. Robert; Singh, Naresh; Bopp, Selina; Volkman, Sarah K.; Hien, Domombele F. S.; Pare, Prislaure S. L.; Yerbanga, Rakiswende S.; Diabate, Abdoullaye; Dabire, Roch K.; Lefevre, Thierry; Wirth, Dyann F.; Catteruccia, Flaminia 分享 收藏
The Plasmodium falciparum ABC transporter ABCI3 confers parasite strain-dependent pleiotropic antimalarial drug resistance Murithi, James M.; Deni, Ioanna; Pasaje, Charisse Flerida A.; Okombo, John; Bridgford, Jessica L.; Gnadig, Nina F.; Edwards, Rachel L.; Yeo, Tomas; Mok, Sachel; Burkhard, Anna Y.; Coburn-Flynn, Olivia; Istvan, Eva S.; Sakata-Kato, Tomoyo; Gomez-Lorenzo, Maria G.; Cowell, Annie N.; Wicht, Kathryn J.; Le Manach, Claire; Kalantarov, Gavreel F.; Dey, Sumanta; Duffey, Maelle; Laleu, Benoit; Lukens, Amanda K.; Ottilie, Sabine; Vanaerschot, Manu; Trakht, Ilya N.; Gamo, Francisco-Javier; Wirth, Dyann F.; Goldberg, Daniel E.; John, Audrey R. Odom; Chibale, Kelly; Winzeler, Elizabeth A.; Niles, Jacquin C.; Fidock, David A. 分享 收藏
Adaptive laboratory evolution in S. cerevisiae highlights role of transcription factors in fungal xenobiotic resistance 酿酒酵母的适应性实验室进化突出了转录因子在真菌异源生物抗性中的作用 Ottilie, Sabine; Luth, Madeline R.; Hellemann, Erich; Goldgof, Gregory M.; Vigil, Eddy; Kumar, Prianka; Cheung, Andrea L.; Song, Miranda; Godinez-Macias, Karla P.; Carolino, Krypton; Yang, Jennifer; Lopez, Gisel; Abraham, Matthew; Tarsio, Maureen; LeBlanc, Emmanuelle; Whitesell, Luke; Schenken, Jake; Gunawan, Felicia; Patel, Reysha; Smith, Joshua; Love, Melissa S.; Williams, Roy M.; McNamara, Case W.; Gerwick, William H.; Ideker, Trey; Suzuki, Yo; Wirth, Dyann F.; Lukens, Amanda K.; Kane, Patricia M.; Cowen, Leah E.; Durrant, Jacob D.; Winzeler, Elizabeth A. 分享 收藏
Chemogenomics identifies acetyl-coenzyme A synthetase as a target for malaria treatment and prevention Summers, Robert L.; Pasaje, Charisse Flerida A.; Pisco, Joao P.; Striepen, Josefine; Luth, Madeline R.; Kumpornsin, Krittikorn; Carpenter, Emma F.; Munro, Justin T.; Lin, De; Plater, Andrew; Punekar, Avinash S.; Shepherd, Andrew M.; Shepherd, Sharon M.; Vanaerschot, Manu; Murithi, James M.; Rubiano, Kelly; Akidi, Asli; Ottilie, Sabine; Mittal, Nimisha; Dilmore, A. Hazel; Won, Madalyn; Mandt, Rebecca E. K.; McGowen, Kerry; Owen, Edward; Walpole, Chris; Llinas, Manuel; Lee, Marcus C. S.; Winzeler, Elizabeth A.; Fidock, David A.; Gilbert, Ian H.; Wirth, Dyann F.; Niles, Jacquin C.; Baragana, Beatriz; Lukens, Amanda K. 分享 收藏
Plasmodium falciparum genomic surveillance reveals spatial and temporal trends, association of genetic and physical distance, and household clustering Sy, Mouhamad; Deme, Awa B.; Warren, Joshua L.; Early, Angela; Schaffner, Stephen; Daniels, Rachel F.; Dieye, Baba; Ndiaye, Ibrahima Mbaye; Diedhiou, Younous; Mbaye, Amadou Moctar; Volkman, Sarah K.; Hartl, Daniel L.; Wirth, Dyann F.; Ndiaye, Daouda; Bei, Amy K. 分享 收藏
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Prioritization of Molecular Targets for Antimalarial Drug Discovery 优先考虑抗疟药物发现的分子靶标 Forte, Barbara; Ottilie, Sabine; Plater, Andrew; Campo, Brice; Dechering, Koen J.; Javier Gamo, Francisco; Goldberg, Daniel E.; Istvan, Eva S.; Lee, Marcus; Lukens, Amanda K.; McNamara, Case W.; Niles, Jacquin C.; Okombo, John; Pasaje, Charisse Flerida A.; Siegel, Miles G.; Wirth, Dyann; Wyllie, Susan; Fidock, David A.; Baragana, Beatriz; Winzeler, Elizabeth A.; Gilbert, Ian H. 分享 收藏
MalDA, Accelerating Malaria Drug Discovery Yang, Tuo; Ottilie, Sabine; Istvan, Eva S.; Godinez-Macias, Karla P.; Lukens, Amanda K.; Baragana, Beatriz; Campo, Brice; Walpole, Chris; Niles, Jacquin C.; Chibale, Kelly; Dechering, Koen J.; Llinas, Manuel; Lee, Marcus C. S.; Kato, Nobutaka; Wyllie, Susan; McNamara, Case W.; Gamo, Francisco Javier; Burrows, Jeremy; Fidock, David A.; Goldberg, Daniel E.; Gilbert, Ian H.; Wirth, Dyann F.; Winzeler, Elizabeth A. 分享 收藏
A framework for microbiome science in public health 公共卫生中的微生物组科学框架 Wilkinson, Jeremy E.; Franzosa, Eric A.; Everett, Christine; Li, Chengchen; Hu, Frank B.; Wirth, Dyann F.; Song, Mingyang; Chan, Andrew T.; Rimm, Eric; Garrett, Wendy S.; Huttenhower, Curtis 分享 收藏
Polymorphisms in Plasmodium falciparum chloroquine resistance transporter (Pfcrt) and multidrug-resistant gene 1 (Pf mdr-1) in Nigerian children 10 years post-adoption of artemisinin-based combination treatments Kayode, Adeyemi T.; Akano, Kazeem; Ajogbasile, Fehintola V.; Uwanibe, Jessica N.; Oluniyi, Paul E.; Bankole, Bolajoko E.; Eromon, Philomena J.; Sowunmi, Akintunde; Folarin, Onikepe A.; Volkman, Sarah K.; McInnis, Bronwyn; Sabeti, Pardis; Wirth, Dyann F.; Happi, Christian T. 分享 收藏
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