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Guinan Shen

Heilongjiang Bayi Agricultural University
H指数:17
被引数:820

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Two novel 1,4-naphthoquinone derivatives induce human gastric cancer cell apoptosis and cell cycle arrest by regulating reactive oxygen species-mediated MAPK/Akt/STAT3 signaling pathways

两种新型1，4-萘醌衍生物通过调节活性氧介导的MAPK/Akt/STAT3信号通路诱导人胃癌细胞凋亡和细胞周期阻滞

MOLECULAR MEDICINE REPORTS
IF3.5
2019-07-1527
OAAI
Wang, Hao; Luo, Ying-Hua; Shen, Gui-Nan; Piao, Xian-Ji; Xu, Wan-Ting; Zhang, Yi; Wang, Jia-Ru; Feng, Yu-Chao; Li, Jin-Qian; Zhang, Yu; Zhang, Tong; Wang, Shi-Nong; Xue, Hui; Wang, Hong-Xing; Wang, Chang-Yuan; Jin, Cheng-Hao
The design of 1,4-naphthoquinone derivatives and mechanisms underlying apoptosis induction through ROS-dependent MAPK/Akt/STAT3 pathways in human lung cancer cells

1，4-萘醌衍生物的设计及其通过ROS依赖性MAPK/Akt/STAT3途径诱导人肺癌细胞凋亡的机制

BIOORGANIC & MEDICINAL CHEMISTRY
IF3
2019-04-0119
PREAI
Zhang, Yi; Luo, Ying-Hua; Piao, Xian-Ji; Shen, Gui-Nan; Wang, Jia-Ru; Feng, Yu-Chao; Li, Jin-Qian; Xu, Wan-Ting; Zhang, Yu; Zhang, Tong; Wang, Chang-Yuan; Jin, Cheng-Hao
Novel 1,4-naphthoquinone derivatives induce reactive oxygen species-mediated apoptosis in liver cancer cells

新型1，4-萘醌衍生物诱导活性氧介导的肝癌细胞凋亡

MOLECULAR MEDICINE REPORTS
IF3.5
2018-12-2119
OAAI
Wang, Yue; Luo, Ying-Hua; Piao, Xian-Ji; Shen, Gui-Nan; Meng, Ling-Qi; Zhang, Yi; Wang, Jia-Ru; Li, Jin-Qian; Wang, Hao; Xu, Wan-Ting; Liu, Yang; Zhang, Yu; Zhang, Tong; Wang, Shi-Nong; Sun, Hu-Nan; Han, Ying-Hao; Jin, Mei-Hua; Zang, Yan-Qing; Zhang, Dong-Jie; Jin, Cheng-Hao
Cryptotanshinone induces reactive oxygen species-mediated apoptosis in human rheumatoid arthritis fibroblast-like synoviocytes

隐丹参酮诱导活性氧介导的人类风湿关节炎成纤维样滑膜细胞凋亡

INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE
IF5.8
2018-12-0320
OAAI
Sun, Hu-Nan; Luo, Ying-Hua; Meng, Ling-Qi; Piao, Xian-Ji; Wang, Yue; Wang, Jia-Ru; Wang, Hao; Zhang, Yi; Li, Jin-Qian; Xu, Wan-Ting; Liu, Yang; Zhang, Yu; Zhang, Tong; Han, Ying-Hao; Jin, Mei-Hua; Shen, Gui-Nan; Zang, Yan-Qing; Cao, Long-Kui; Zhang, Dong-Jie; Jin, Cheng-Hao
The compound 2-(naphthalene-2-thio)-5,8-dimethoxy-1,4-naphthoquinone induces apoptosis via reactive oxygen species-regulated mitogen-activated protein kinase, protein kinase B, and signal transducer and activator of transcription 3 signaling in human gastric cancer cells

化合物2-(naphthalene-2-thio)-5，8-二甲氧基-1，4-萘醌通过活性氧调节的丝裂原活化蛋白激酶，蛋白激酶B和信号转导和转录激活因子3信号诱导人胃癌细胞凋亡细胞

DRUG DEVELOPMENT RESEARCH
IF4.2
2018-09-1715
PREAI
Wang, Jia-Ru; Shen, Gui-Nan; Luo, Ying-Hua; Piao, Xian-Ji; Shen, Meng; Liu, Chang; Wang, Yue; Meng, Ling-Qi; Zhang, Yi; Wang, Hao; Li, Jin-Qian; Xu, Wan-Ting; Liu, Yang; Sun, Hu-Nan; Han, Ying-Hao; Jin, Mei-Hua; Cao, Long-Kui; Jin, Cheng-Hao
Novel 1,4-naphthoquinone derivatives induce apoptosis via ROS-mediated p38/MAPK, Akt and STAT3 signaling in human hepatoma Hep3B cells

新型1，4-萘醌衍生物通过ROS介导的p38/MAPK，Akt和STAT3信号诱导人肝癌Hep3B细胞凋亡

INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
IF2.8
2018-03-0133
PREAI
Liu, Chang; Shen, Gui-Nan; Luo, Ying-Hua; Piao, Xian-Ji; Jiang, Xue-Yuan; Meng, Ling-Qi; Wang, Yue; Zhang, Yi; Wang, Jia-Ru; Wang, Hao; Xu, Wan-Ting; Li, Jin-Qian; Liu, Yang; Wu, Yi-Qin; Sun, Hu-Nan; Han, Ying-Hao; Jin, Mei-Hua; Cui, Yu-Dong; Fang, Nan-Zhu; Jin, Cheng-Hao
Quinalizarin exerts an anti-tumour effect on lung cancer A549 cells by modulating the Akt, MAPK, STAT3 and p53 signalling pathways

醌茜素通过调节Akt，MAPK，STAT3和p53信号通路对肺癌A549细胞的抗肿瘤作用

MOLECULAR MEDICINE REPORTS
IF3.5
2017-11-2022
OAAI
Meng, Ling-Qi; Liu, Chang; Luo, Ying-Hua; Piao, Xian-Ji; Wang, Yue; Zhang, Yi; Wang, Jia-Ru; Wang, Hao; Xu, Wan-Ting; Liu, Yang; Wu, Yi-Qin; Sun, Hu-Nan; Han, Ying-Hao; Jin, Mei-Hua; Shen, Gui-Nan; Zang, Yan-Qing; Li, Jing; Fang, Nan-Zhu; Cui, Yu-Dong; Jin, Cheng-Hao

研究方向

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