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Ranking mAb-excipient interactions in biologics formulations by NMR spectroscopy and computational approaches Zhang, Chunting; Gossert, Steven T.; Williams, Jonathan; Little, Michael; Barros, Marilia; Dear, Barton; Falk, Bradley; Kanthe, Ankit D.; Garmise, Robert; Mueller, Luciano; Ilott, Andrew; Abraham, Anuji 分享 收藏
Atropisomer Control in Macrocyclic Factor Vlla Inhibitors (vol 59, pg 4007, 2016) Glunz, Peter W.; Mueller, Luciano; Cheney, Daniel L.; Ladziata, Vladimir; Zou, Yan; Wurtz, Nicholas R.; Wei, Anzhi; Wong, Pancras C.; Wexler, Ruth R.; Priestley, E. Scott 分享 收藏
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Mapping the Energetic Epitope of an Antibody/Interleukin-23 Interaction with Hydrogen/Deuterium Exchange, Fast Photochemical Oxidation of Proteins Mass Spectrometry, and Alanine Shave Mutagenesis Li, Jing; Wei, Hui; Krystek, Stanley R., Jr.; Bond, Derek; Brender, Ty M.; Cohen, Daniel; Feiner, Jena; Hamacher, Nels; Harshman, Johanna; Huang, Richard Y. -C.; Julien, Susan H.; Lin, Zheng; Moore, Kristina; Mueller, Luciano; Noriega, Claire; Sejwal, Preeti; Sheppard, Paul; Stevens, Brenda; Chen, Guodong; Tyrniak, Adrienne A.; Gross, Michael L.; Schneeweis, Lumelle A. 分享 收藏
Discovery of a Potent Acyclic, Tripeptidic, Acyl Sulfonamide Inhibitor of Hepatitis C Virus NS3 Protease as a Back-up to Asunaprevir with the Potential for Once-Daily Dosing Sun, Li-Qiang; Mull, Eric; Zheng, Barbara; D'Andrea, Stanley; Zhao, Qian; Wang, Alan Xiangdong; Sin, Ny; Venables, Brian L.; Sit, Sing-Yuen; Chen, Yan; Chen, Jie; Cocuzza, Anthony; Bilder, Donna M.; Mathur, Arvind; Ranipulla, Richard; Chen, Bang-Chi; Palani, Theerthagiri; Ganesan, Sivakumar; Arunachalam, Pirama Nayagam; Falk, Paul; Levine, Steven; Chen, Chaoqun; Friborg, Jacques; Yu, Fei; Hernandez, Dennis; Sheaffer, Amy K.; Knipe, Jay O.; Han, Yong-Hae; Schartman, Richard; Donoso, Maria; Mosure, Kathy; Sinz, Michael W.; Zvyaga, Tatyana; Rajamani, Ramkumar; Kish, Kevin; Tredup, Jeffrey; Klei, Herbert E.; Gao, Qi; Ng, Alicia; Mueller, Luciano; Grasela, Dennis M.; Adams, Stephen; Loy, James; Levesaue, Paul C.; Sun, Huabin; Shi, Hong; Sun, Lucy; Warner, William; Li, Danshi; Zhu, Jialong; Wang, Ying-Kai; Fang, Hua; Cockett, Mark I.; Meanwell, Nicholas A.; McPhee, Fiona; Scola, Paul M. 分享 收藏
Atropisomer Control in Macrocyclic Factor VIIa Inhibitors Glunz, Peter W.; Mueller, Luciano; Cheney, Daniel L.; Ladziata, Vladimir; Zou, Yan; Wurtz, Nicholas R.; Wei, Anzhi; Wong, Pancras C.; Wexler, Ruth R.; Priestley, E. Scott 分享 收藏
Discovery of Novel P1 Groups for Coagulation Factor VIIa Inhibition Using Fragment-Based Screening Cheney, Daniel L.; Bozarth, Jeffrey M.; Metzler, William J.; Morin, Paul E.; Mueller, Luciano; Newitt, John A.; Nirschl, Alexandra H.; Rendina, Alan R.; Tamura, James K.; Wei, Anzhi; Wen, Xiao; Wurtz, Nicholas R.; Seiffert, Dietmar A.; Wexler, Ruth R.; Priestley, E. Scott 分享 收藏
The Discovery of Asunaprevir (BMS-650032), An Orally Efficacious NS3 Protease Inhibitor for the Treatment of Hepatitis C Virus Infection Scola, Paul M.; Sun, Li-Qiang; Wang, Alan Xiangdong; Chen, Jie; Sin, Ny; Venables, Brian L.; Sit, Sing-Yuen; Chen, Yan; Cocuzza, Anthony; Bilder, Donna M.; D'Andrea, Stanley V.; Zheng, Barbara; Hewawasam, Piyasena; Tu, Yong; Friborg, Jacques; Falk, Paul; Hernandez, Dennis; Levine, Steven; Chen, Chaoqun; Yu, Fei; Sheaffer, Amy K.; Zhai, Guangzhi; Barry, Diana; Knipe, Jay O.; Han, Yong-Hae; Schartman, Richard; Donoso, Maria; Mosure, Kathy; Sinz, Michael W.; Zvyaga, Tatyana; Good, Andrew C.; Rajamani, Ramkumar; Kish, Kevin; Tredup, Jeffrey; Klei, Herbert E.; Gao, Qi; Mueller, Luciano; Colonno, Richard J.; Grasela, Dennis M.; Adams, Stephen P.; Loy, James; Levesque, Paul C.; Sun, Huabin; Shi, Hong; Sun, Lucy; Warner, William; Li, Danshi; Zhu, Jialong; Meanwell, Nicholas A.; McPhee, Fiona 分享 收藏
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Multiple and single binding modes of fragment-like kinase inhibitors revealed by molecular modeling, residue type-selective protonation, and nuclear overhauser effects Constantine, Keith L.; Mueller, Luciano; Metzler, William J.; McDonnell, Patricia A.; Todderud, Gordon; Goldfarb, Valentina; Fan, Yi; Newitt, John A.; Kiefer, Susan E.; Gao, Mian; Tortolani, David; Vaccaro, Wayne; Tokarski, John 分享 收藏
NMR structure of a potent small molecule inhibitor bound to human keratinocyte fatty acid-binding protein McDonnell, Patricia A.; Constantine, Keith L.; Goldfarb, Valentina; Johnson, Stephen R.; Sulsky, Richard; Magnin, David R.; Robl, Jeffrey A.; Caulfield, Thomas J.; Parker, Rex A.; Taylor, David S.; Adam, Leonard P.; Metzler, William J.; Mueller, Luciano; Farmer, Bennett T., II 分享 收藏
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