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N

Nicholas A. Meanwell

university of california irvine

63H指数
468论文数
2.5W被引数
收录论文 152
发表时间
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Structural Aspects of Proline Methanologues in Drug Design, Optimization, and Development脯氨酸甲醚类在药物设计、优化和开发中的结构方面
errJournal of Organic Chemistry
IF3.6
err2026-02-01
err0
PREAI
errHanessian, Stephen; Meanwell, Nicholas A.
err分享
err收藏
Design; Synthesis; and T Cell Checkpoint Combination Potential Of First-In-Class DGKα/ζ Inhibitor BMS-986408设计；合成；以及第一类DGKα/ζ抑制剂的T细胞检查点组合潜力 BMS-986408
errJournal of Medicinal Chemistry
IF6.8
err2025-10-14
err0
PREAI
errDenise C. Grünenfelder; Upender Velaparthi; Jayakumar S. Warrier; Louis Chupak; Chetan Padmakar Darne; Bireshwar Dasgupta; T. G. Murali Dhar; Min Ding; Robert Gentles; Yazhong Huang; Prasada R. Jalagam; Manjunatha Narayana Rao Kamble; Raju Mannoori; Scott Martin; Shana L. Posy; Hasibur Rahaman; Thiruvenkadam Raja; Kotha Rathnakar Reddy; Saumya Roy; Amy Sarjeant; John S. Tokarski; Gopikishan Tonukunuru; Sivasudar Velaiah; Xiaofan Zheng; Aravind Anandam; Gopal Dhar; Shailesh Dudhgaonkar; R. Marcus Fancher; Siddheshwar Layane; Si-Qi Liu; Swagatam Ray; Hongchen Qiu; Susan Wee; Sagnik Chatterjee; Myrtle Davis; Elizabeth Dierks; Anoop Kumar; Thanga Mariappan; Robin Moore; Bokka Venkata Murali; Ramola Sane; Dana Banas; Deepa Calambur; Erica Cook; Priya Dehal; Hua Fang; Gregory Locke; Joseph G. Naglich; Madhu Sudhan Ravindran; Lumelle Schneeweis; Debarati M. Tagore; Mark Witmer; Abigail E. Witt; Dianlin Xie; Emma Lees; Michael Wichroski; Nicholas A. Meanwell; Robert Borzilleri; Richard E. Olson
err分享
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Carbon atom σ-hole tetrel bonding – a non-bonded interaction with potential application in drug design碳原子σ-空穴类碳键——一种在药物设计中具有潜在应用的非键相互作用
errMedicinal Chemistry Research
IF3.1
err2025-08-09
err0
PREAI
errNicholas A. Meanwell
err分享
err收藏
Meeting report: 38th international conference on antiviral research in Las Vegas, United States of America, March 17–21, 2025会议报告：第38届抗病毒研究国际会议，美国拉斯维加斯，2025年3月17–21日
errAntiviral Research
IF4
err2025-07-03
err0
PREAI
errRobert Jordan; Nancie M. Archin; Valeria Cagno; Joy Y. Feng; Haitao Guo; Lara J. Herrero; Zlatko Janeba; Nicholas A. Meanwell; Jennifer Moffat; Johan Neyts; Joana Rocha-Pereira; Kathie L. Seley-Radtke; Timothy P. Sheahan; Jessica R. Spengler; Stephen R. Welch; Xuping Xie; Hovakim Zakaryan; Luis M. Schang; David Durantel
err分享
err收藏
Virtual screening: hope, hype, and the fine line in between虚拟筛选: 希望，炒作和两者之间的细线
errEXPERT OPINION ON DRUG DISCOVERY
IF4.9
err2025-01-27
err0
PREAI
errNada, Hossam; Meanwell, Nicholas A.; Gabr, Moustafa T.
err分享
err收藏
Invention of VH-937, a Potent HIV-1 Maturation Inhibitor with the Potential for Infrequent Oral Dosing in Humans
errACS MEDICINAL CHEMISTRY LETTERS
IF4
err2024-10-17
err0
PREAI
errSit, Sing-Yuen; Chen, Yan; Chen, Jie; Venables, Brian L.; Swidorski, Jacob J.; Xu, Li; Sin, Ny; Hartz, Richard A.; Lin, Zeyu; Zhang, Sharon; Li, Zhufang; Wu, Dauh-Rurng; Li, Peng; Kempson, James; Hou, Xiaoping; Shanmugam, Yoganand; Parker, Dawn; Jenkins, Susan; Simmermacher, Jean; Falk, Paul; Mcauliffe, Brian; Cockett, Mark; Hanumegowda, Umesh; Dicker, Ira; Krystal, Mark; Meanwell, Nicholas A.; Regueiro-Ren, Alicia
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err收藏
Preclinical Profile of the HIV-1 Maturation Inhibitor VH3739937HIV-1成熟抑制剂VH3739937的临床前概况
errVIRUSES-BASEL
IF3.5
err2024-09-24
err1
errOAAI
errMcAuliffe, Brian; Falk, Paul; Chen, Jie; Chen, Yan; Sit, Sing-Yuen; Swidorski, Jacob; Hartz, Richard A.; Xu, Li; Venables, Brian; Sin, Ny; Meanwell, Nicholas A.; Regueiro-Ren, Alicia; Wensel, David; Hanumegowda, Umesh; Krystal, Mark
err分享
err收藏
Challenges with the Synthesis of a Macrocyclic Thioether Peptide: From Milligram to Multigram Using Solid Phase Peptide Synthesis (SPPS)
errJOURNAL OF ORGANIC CHEMISTRY
IF3.6
err2024-04-23
err4
PREAI
errKempson, James; Zhao, Rulin; Pawluczyk, Joseph; Wang, Bei; Zhang, Huiping; Hou, Xiaoping; Allen, Martin P.; Wu, Dauh-Rurng; Li, Peng; Yip, Shiuhang; Smith, Aaron; Traeger, Sarah C.; Huang, Stella; Cutrone, Jingfang; Mukherjee, Subha; Sfouggatakis, Chris; Poss, Michael; Scola, Paul M.; Meanwell, Nicholas A.; Carter, Percy H.; Mathur, Arvind
err分享
err收藏
Tying the knot with lysine
errNATURE REVIEWS CHEMISTRY
IF51.7
err2024-03-18
err0
PREAI
errKoperniku, Ana; Meanwell, Nicholas A.
err分享
err收藏
Development, Characterization, and Radiation Dosimetry Studies of 18F-BMS-986229, a 18F-Labeled PD-L1 Macrocyclic Peptide PET Tracer
errMOLECULAR IMAGING AND BIOLOGY
IF2.5
err2023-12-20
err2
errOAAI
errKim, Joonyoung; Donnelly, David J.; Tran, Tritin; Pena, Adrienne; Shorts, Andrea Olga; Petrone, Thomas V.; Zhang, Yunhui; Boy, Kenneth M.; Scola, Paul M.; Tenney, Daniel J.; Poss, Michael A.; Soars, Matthew G.; Bonacorsi, Samuel J.; Cole, Erin L.; Grootendorst, Diederik J.; Chow, Patrick L.; Meanwell, Nicholas A.; Du, Shuyan
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err收藏
The discovery and evaluation of [18F]BMS-986229, a novel macrocyclic peptide PET radioligand for the measurement of PD-L1 expression and in-vivo PD-L1 target engagement
errEuropean Journal of Nuclear Medicine and Molecular Imaging
IF7.6
err2023-12-05
err5
PREAI
errDonnelly, David J.; Kim, Joonyoung; Tran, Tritin; Scola, Paul M.; Tenney, Daniel; Pena, Adrienne; Petrone, Thomas; Zhang, Yunhui; Boy, Kenneth M.; Poss, Michael A.; Cole, Erin L.; Soars, Matthew G.; Johnson, Benjamin M.; Cohen, Daniel; Batalla, Daniel; Chow, Patrick L.; Shorts, Andrea Olga; Du, Shuyan; Meanwell, Nicholas A.; Bonacorsi Jr, Samuel J.
err分享
err收藏
DGKα/ζ inhibitors combine with PD-1 checkpoint therapy to promote T cell-mediated antitumor immunity
errSCIENCE TRANSLATIONAL MEDICINE
IF14.6
err2023-10-25
err7
PREAI
errWichroski, Michael; Benci, Joseph; Liu, Si-Qi; Chupak, Louis; Fang, Jie; Cao, Carolyn; Wang, Cindy; Onorato, Joelle; Qiu, Hongchen; Shan, Yongli; Banas, Dana; Powles, Ryan; Locke, Gregory; Witt, Abigail; Stromko, Caitlyn; Qi, Huilin; Zheng, Xiaofan; Martin, Scott; Ding, Min; Gentles, Robert; Meanwell, Nicholas; Velaparthi, Upender; Olson, Richard; Wee, Susan; Tenney, Daniel; Parker, Christopher G.; Cravatt, Benjamin F.; Lawrence, Michael; Borzilleri, Robert; Lees, Emma
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Sub-stoichiometric Modulation of Viral Targets-Potent Antiviral Agents That Exploit Target Vulnerability
errACS MEDICINAL CHEMISTRY LETTERS
IF4
err2023-07-11
err4
errOAAI
errMeanwell, Nicholas A.
err分享
err收藏
Discovery of Potent, Dual-Inhibitors of Diacylglycerol Kinases Alpha and Zeta Guided by Phenotypic Optimization
errACS MEDICINAL CHEMISTRY LETTERS
IF4
err2023-06-12
err8
PREAI
errChupak, Louis; Wichroski, Michael; Zheng, Xiaofan; Ding, Min; Martin, Scott; Allard, Christopher; Shi, Jianliang; Gentles, Robert; Meanwell, Nicholas A.; Fang, Jie; Tenney, Daniel; Tokarski, John; Cao, Carolyn; Wee, Susan
err分享
err收藏
Anagrelide: A Clinically Effective cAMP Phosphodiesterase 3A Inhibitor with Molecular Glue PropertiesAnagrelide: 具有分子胶水特性的临床有效的cAMP磷酸二酯酶3A抑制剂
errACS MEDICINAL CHEMISTRY LETTERS
IF4
err2023-03-28
err4
errOAAI
errMeanwell, Nicholas A.
err分享
err收藏
Applications of Bioisosteres in the Design of Biologically Active Compounds
errJOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
IF6.2
err2023-03-24
err70
PREAI
errMeanwell, Nicholas A.
err分享
err收藏
Some Observations and Guidance on Perspectives in the Journal of Medicinal Chemistry
errJOURNAL OF MEDICINAL CHEMISTRY
IF6.8
err2023-02-15
err1
PREAI
errBrown, Dean G.; Meanwell, Nicholas A.; Lindsley, Craig W.
err分享
err收藏
Potent Long-Acting Inhibitors Targeting the HIV-1 Capsid Based on a Versatile Quinazolin-4-one Scaffold
errJOURNAL OF MEDICINAL CHEMISTRY
IF6.8
err2023-01-31
err13
PREAI
errGillis, Eric P.; Parcella, Kyle; Bowsher, Michael; Cook, James H.; Iwuagwu, Christiana; Naidu, B. Narasimhulu; Patel, Manoj; Peese, Kevin; Huang, Haichang; Valera, Lourdes; Wang, Chunfu; Kieltyka, Kasia; Parker, Dawn D.; Simmermacher, Jean; Arnoult, Eric; Nolte, Robert T.; Wang, Liping; Bender, John A.; Frennesson, David B.; Saulnier, Mark; Wang, Alan Xiangdong; Meanwell, Nicholas A.; Belema, Makonen; Hanumegowda, Umesh; Jenkins, Susan; Krystal, Mark; Kadow, John F.; Cockett, Mark; Fridell, Robert
err分享
err收藏
Metallaphotoredox Decarboxylative Arylation of Natural Amino Acids via an Elusive Mechanistic Pathway
errACS CATALYSIS
IF13.1
err2022-12-22
err19
PREAI
errPitchai, Manivel; Ramirez, Antonio; Mayder, Don M.; Ulaganathan, Sankar; Kumar, Hemantha; Aulakh, Darpandeep; Gupta, Anuradha; Mathur, Arvind; Kempson, James; Meanwell, Nicholas; Hudson, Zachary M.; Oderinde, Martins S.
err分享
err收藏
Synthesis, Structure-Activity Relationships, and In Vivo Evaluation of Novel C-17 Amine Derivatives Based on GSK3640254 as HIV-1 Maturation Inhibitors with Broad Spectrum Activity
errJOURNAL OF MEDICINAL CHEMISTRY
IF6.8
err2022-11-28
err2
PREAI
errHartz, Richard A.; Xu, Li; Sit, Sing-Yuen; Chen, Jie; Venables, Brian L.; Lin, Zeyu; Zhang, Sharon; Li, Zhufang; Parker, Dawn; Simmons, Tara S.; Jenkins, Susan; Hanumegowda, Umesh M.; Dicker, Ira; Krystal, Mark; Meanwell, Nicholas A.; Regueiro-Ren, Alicia
err分享
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研究方向

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