Jörg Bentzien - Publications, H-index & Citations

Jörg Bentzien

Boehringer Ingelheim

19H指数

28论文数

1.1K被引数

收录论文 15

发表时间

Perspectives on current approaches to virtual screening in drug discovery 当前药物发现中虚拟筛选方法的观点

EXPERT OPINION ON DRUG DISCOVERY

IF4.9

2024-08-12

PREAI

Muegge, Ingo; Bentzien, Jorg; Ge, Yunhui

In Silico Models of Human PK Parameters. Prediction of Volume of Distribution Using an Extensive Data Set and a Reduced Number of Parameters

JOURNAL OF PHARMACEUTICAL SCIENCES

IF3.8

2021-01-01

PREAI

Lombardo, Franco; Bentzien, Jorg; Berellini, Giuliano; Muegge, Ingo

Crowdsourcing and open innovation in drug discovery: recent contributions and future directions

DRUG DISCOVERY TODAY

IF7.5

2020-12-01

OAAI

Thompson, David C.; Bentzien, Jorg

Kinase Crystal Miner: A Powerful Approach to Repurposing 3D Hinge Binding Fragments and Its Application to Finding Novel Bruton Tyrosine Kinase Inhibitors

JOURNAL OF CHEMICAL INFORMATION AND MODELING

IF5.3

2017-08-28

PREAI

Mukherjee, Prasenjit; Bentzien, Jorg; Bosanac, Todd; Mao, Wang; Burke, Michael; Muegge, Ingo

Automatically updating predictive modeling workflows support decision-making in drug design

FUTURE MEDICINAL CHEMISTRY

IF3.4

2016-09-01

PREAI

Muegge, Ingo; Bentzien, Jorg; Mukherjee, Prasenjit; Hughes, Robert O.

Crowdsourcing in pharma: a strategic framework

DRUG DISCOVERY TODAY

IF7.5

2015-07-01

PREAI

Bentzien, Joerg; Bharadwaj, Ragu; Thompson, David C.

Identification of Highly Efficacious Glucocorticoid Receptor Agonists with a Potential for Reduced Clinical Bone Side Effects

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2014-02-07

PREAI

Harcken, Christian; Riether, Doris; Kuzmich, Daniel; Liu, Pingrong; Betageri, Raj; Ralph, Mark; Emmanuel, Michel; Reeves, Jonathan T.; Berry, Angela; Souza, Donald; Nelson, Richard M.; Kukulka, Alison; Fadra, Tazmeen N.; Zuvela-Jelaska, Ljiljana; Dinallo, Roger; Bentzien, Joerg; Nabozny, Gerald H.; Thomson, David S.

In silico predictions of genotoxicity for aromatic amines

FRONTIERS IN BIOSCIENCE-LANDMARK

IF3.1

2014-01-01

OAAI

Bentzien, Jorg; Muegge, Ingo

Crowd computing: using competitive dynamics to develop and refine highly predictive models

DRUG DISCOVERY TODAY

IF7.5

2013-05-01

PREAI

Bentzien, Joerg; Muegge, Ingo; Hamner, Ben; Thompson, David C.

Identification of a Potent Sodium Hydrogen Exchanger Isoform 1 (NHE1) Inhibitor with a Suitable Profile for Chronic Dosing and Demonstrated Cardioprotective Effects in a Preclinical Model of Myocardial Infarction in the Rat

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2012-08-06

PREAI

Huber, John D.; Bentzien, Joerg; Boyer, Stephen J.; Burke, Jennifer; De Lombaert, Stephane; Eickmeier, Christian; Guo, Xin; Haist, James V.; Hickey, Eugene R.; Kaplita, Paul; Karmazyn, Morris; Kemper, Raymond; Kennedy, Charles A.; Kirrane, Thomas; Madwed, Jeffrey B.; Mainolfi, Elizabeth; Nagaraja, Nelamangara; Soleymanzadeh, Fariba; Swinamer, Alan; Eldrup, Anne B.

DemQSAR: predicting human volume of distribution and clearance of drugs

JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN

IF3.1

2011-11-20

PREAI

Demir-Kavuk, Ozgur; Bentzien, Joerg; Muegge, Ingo; Knapp, Ernst-Walter

Nonsteroidal Dissociated Glucocorticoid Agonists Containing Azaindoles as Steroid A-Ring Mimetics

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2010-08-24

PREAI

Riether, Doris; Harcken, Christian; Razavi, Hossein; Kuzmich, Daniel; Gilmore, Thomas; Bentzien, Joerg; Pack, Edward J., Jr.; Souza, Donald; Nelson, Richard M.; Kukulka, Alison; Fadra, Tazmeen N.; Zuvela-Jelaska, Ljiljana; Pelletier, Josephine; Dinallo, Roger; Panzenbeck, Mark; Torcellini, Carol; Nabozny, Gerald H.; Thomson, David S.

An in Silico Method for Predicting Ames Activities of Primary Aromatic Amines by Calculating the Stabilities of Nitrenium Ions

JOURNAL OF CHEMICAL INFORMATION AND MODELING

IF5.3

2010-01-15

PREAI

Bentzien, Joerg; Hickey, Eugene R.; Kemper, Raymond A.; Brewer, Mark L.; Dyekjaer, Jane D.; East, Stephen P.; Whittaker, Mark

Quinol-4-ones as steroid A-ring mimetics in nonsteroidal dissociated glucocorticoid agonists

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2006-12-21

PREAI

Regan, John; Lee, Thomas W.; Zindell, Renee M.; Bekkali, Younes; Bentzien, Jorg; Gilmore, Thomas; Hammach, Abdelhakim; Kirrane, Thomas M.; Kukulka, Alison J.; Kuzmich, Daniel; Nelson, Richard M.; Proudfoot, John R.; Ralph, Mark; Pelletier, Josephine; Souza, Donald; Zuvela-Jelaska, Lijiljana; Nabozny, Gerald; Thomson, David S.

Combining computational and experimental screening for rapid optimization of protein properties

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2002-11-21

236

OAAI

Hayes, RJ; Bentzien, J; Ary, ML; Hwang, MY; Jacinto, JM; Vielmetter, J; Kundu, A; Dahiyat, BI

研究方向