Kohsuke Kanekura

Tokyo Medical University

H指数:31

被引数:3,489

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Nucleolar integrity in isolated nucleoli is governed by electrostatic interactions and altered by disease-associated proteins

核仁完整性在分离的核仁中由静电相互作用调控，并受疾病相关蛋白的影响

Biochemical and Biophysical Research Communications

IF2.2

2026-08-070

PRE

Exosome-like Nanovesicles from Acerola for CRISPR/Cas9 Ribonucleoprotein Delivery to the Central Nervous System

来自阿塞罗拉的类外泌体纳米囊泡，用于CRISPR/Cas9核糖核蛋白递送至中枢神经系统

Molecular Therapy Nucleic Acids

IF6.1

2026-03-120

OAAI

FRET-based biosensor moxCRONOS enables quantitative monitoring of macromolecular crowding in organelles and protein aggregates

基于FRET的生物传感器moxCRONOS实现了对细胞器和大分子聚集体的分子拥挤现象的定量监测

JOURNAL OF BIOCHEMISTRY

IF1.7

2025-09-010

OAAI

Phase separated condensates of ATRX regulate neural progenitor identity

ATRX的相分离凝聚体调控神经祖细胞身份

Nature Communications

IF15.7

2025-07-140

OAAI

Biochemical characteristics of spacer amino acid determine phase-separating behavior and induction of nucleolar stress by arginine-rich dipeptide repeat proteins

间隔氨基酸的生物化学特性决定了精氨酸富集的二肽重复蛋白的相分离行为和核仁应激诱导。

Biochemical and Biophysical Research Communications

IF2.2

2025-06-240

PRE

Excessive expression of progranulin leads to neurotoxicity rather than neuroprotection

过度的progranulin表达会导致神经毒性而非神经保护。

NEUROBIOLOGY OF DISEASE

IF5.6

2025-06-010

OAAI

Graphene Biosensor Differentiating Sensitive Interactions between Ribonucleic Acid and Dipeptide Repeats in Liquid-Liquid Phase Separation

石墨烯生物传感器区分液-液相分离中核糖核酸与二肽重复序列之间的敏感相互作用

ACS APPLIED MATERIALS & INTERFACES

IF8.2

2025-02-170

PRE

Disulfide Bonds of Thyroid Peroxidase Are Critical Elements for Subcellular Localization, Proteasome-Dependent Degradation, and Enzyme Activity

THYROID

IF6.7

2024-05-010

PRE

Transforming growth factor β2 is a neuronal death-inducing ligand for amyloid-β precursor protein

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-2748

OAAI

How can we interpret the relationship between liquid-liquid phase separation and amyotrophic lateral sclerosis?

LABORATORY INVESTIGATION

IF4.2

2022-09-017

OAAI

Effect of Multivalency on Phase-Separated Droplets Consisting of Poly(PR) Dipeptide Repeats and RNA at the Solid/Liquid Interface

ACS OMEGA

IF4.3

2022-06-0310

OAAI

Nuclear microRNAs release paused Pol II via the DDX21-CDK9 complex

CELL REPORTS

IF6.9

2022-04-019

Order controls disordered droplets: structure-function relationships in C9ORF72-derived poly(PR)

AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

IF4.7

2022-02-011

PRE

Chemically oligomerizable TDP-43: a novel chemogenetic tool for studying the pathophysiology of amyotrophic lateral sclerosis

NEURAL REGENERATION RESEARCH

IF6.7

2022-01-011

OAAI

Expression of L-type amino acid transporter 1 is a poor prognostic factor for Non-Hodgkin's lymphoma

SCIENTIFIC REPORTS

IF3.9

2021-11-046

OAAI

Establishment of chemically oligomerizable TAR DNA-binding protein-43 which mimics amyotrophic lateral sclerosis pathology in mammalian cells

LABORATORY INVESTIGATION

IF4.2

2021-10-017

OAAI

Phase separation and toxicity of C9orf72 poly(PR) depends on alternate distribution of arginine

JOURNAL OF CELL BIOLOGY

IF6.4

2021-09-0927

OAAI

Diffusion of LLPS Droplets Consisting of Poly(PR) Dipeptide Repeats and RNA on Chemically Modified Glass Surface

LANGMUIR

IF3.9

2021-04-3014

PREAI

Comprehensive analysis of liver and blood miRNA in precancerous conditions

SCIENTIFIC REPORTS

IF3.9

2020-12-1015

OAAI

A soluble endoplasmic reticulum factor as regenerative therapy for Wolfram syndrome

LABORATORY INVESTIGATION

IF4.2

2020-09-0110

OAAI

Kohsuke Kanekura

个人简介

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