未登录Targeting cancer glycosylation repolarizes tumor-associated macrophages allowing effective immune checkpoint blockade
Stanczak, Michal A.; Mantuano, Natalia Rodrigues; Kirchhammer, Nicole; Sanin, David E.; Jacob, Francis; Coelho, Ricardo; Everest-Dass, Arun V.; Wang, Jinyu; Trefny, Marcel P.; Monaco, Gianni; Barenwaldt, Anne; Gray, Melissa A.; Petrone, Adam; Kashyap, Abhishek S.; Glatz, Katharina; Kasenda, Benjamin; Normington, Karl; Broderick, James; Peng, Li; Pearce, Oliver M. T.; Pearce, Erika L.; Bertozzi, Carolyn R.; Zippelius, Alfred; Laubli, Heinz .png)
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收藏NK cells with tissue-resident traits shape response to immunotherapy by inducing adaptive antitumor immunityKirchhammer, Nicole; Trefny, Marcel P.; Natoli, Marina; Bruecher, Dominik; Smith, Sheena N.; Werner, Franziska; Koch, Victoria; Schreiner, David; Bartoszek, Ewelina; Buchi, Melanie; Schmid, Markus; Breu, Daniel; Hartmann, K. Patricia; Zaytseva, Polina; Thommen, Daniela S.; Laeubli, Heinz; Boettcher, Jan P.; Stanczak, Michal A.; Kashyap, Abhishek S.; Plueckthun, Andreas; Zippelius, Alfred 分享 收藏 AUTOCRINE/PARACRINE FACTORS IN CANCER ASSOCIATED FIBROBLASTS DRIVE IMMUNOSUPPRESSION THROUGH IMPAIRED MYELOID CELL FUNCTIONSSharma, Nikita; Govindaraju, Priya; Bradford, Shermineh; Wang, Yarong; Flynn, Brianna; Lei, Candace Wai Sze; Di Blasi, Varenka Rodriguez; Pignatelli, Jeanine; Liu, Kang; Corse, Emily; Kashyap, Abhishek 分享 收藏 Plinabulin, a Distinct Microtubule-Targeting Chemotherapy, Promotes M1-Like Macrophage Polarization and Anti-tumor ImmunityNatoli, Marina; Herzig, Petra; Pishali Bejestani, Elham; Buchi, Melanie; Ritschard, Reto; Lloyd, G. Kenneth; Mohanlal, Ramon; Tonra, James R.; Huang, Lan; Heinzelmann, Viola; Trub, Marta; Zippelius, Alfred; Kashyap, Abhishek S. 分享 收藏 Optimized antiangiogenic reprogramming of the tumor microenvironment potentiates CD40 immunotherapyKashyap, Abhishek S.; Schmittnaegel, Martina; Rigamonti, Nicolo; Pais-Ferreira, Daniela; Mueller, Philipp; Buchi, Melanie; Ooi, Chia-Huey; Kreuzaler, Matthias; Hirschmann, Petra; Guichard, Alan; Rieder, Natascha; Bill, Ruben; Herting, Frank; Kienast, Yvonne; Dirnhofer, Stefan; Klein, Christian; Hoves, Sabine; Ries, Carola H.; Corse, Emily; De Palma, Michele; Zippelius, Alfred 分享 收藏 GEF-H1 Signaling upon Microtubule Destabilization Is Required for Dendritic Cell Activation and Specific Anti-tumor ResponsesKashyap, Abhishek S.; Fernandez-Rodriguez, Laura; Zhao, Yun; Monaco, Gianni; Trefny, Marcel P.; Yoshida, Naohiro; Martin, Kea; Sharma, Ashwani; Olieric, Natacha; Shah, Pankaj; Stanczak, Michal; Kirchhammer, Nicole; Park, Sung-Moo; Wieckowski, Sebastien; Laubli, Heinz; Zagani, Rachid; Kasenda, Benjamin; Steinmetz, Michel O.; Reinecker, Hans-Christian; Zippelius, Alfred 分享 收藏 Microtubule destabilization by plinabulin generates anti-tumor immune response through repolarization of intratumoral macrophagesBejestani, Elham Pishali; Lloyd, G. Kenneth; Buchi, Melanie; Ritschard, Reto; Herzig, Petra; Mohanlal, Ramon; Huang, Lan; Tonra, James R.; Zippelius, Alfred; Kashyap, Abhishek 分享 收藏 LNAplus™ antisense oligonucleotides targeting CD39 and CD73 have potent anti-tumor activity by modulating immunosuppressive tumor microenvironmentFestag, Julia; Thelemann, Tamara; Kashyap, Abhishek S.; Klar, Richard; Kallert, Sandra; Buchi, Melanie; Hinterwimmer, Lisa; Schell, Monika; Raith, Stefanie; Michel, Sven; Zippelius, Alfred; Jaschinski, Frank 分享 收藏 Antisense oligonucleotide targeting CD39 improves anti-tumor T cell immunity靶向CD39的反义寡核苷酸改善抗肿瘤T细胞免疫Kashyap, Abhishek S.; Thelemann, Tamara; Klar, Richard; Kallert, Sandra M.; Festag, Julia; Buchi, Melanie; Hinterwimmer, Lisa; Schell, Monika; Michel, Sven; Jaschinski, Frank; Zippelius, Alfred 分享 收藏 A novel anti-HER2 anthracycline-based antibody-drug conjugate induces adaptive anti-tumor immunity and potentiates PD-1 blockade in breast cancer一种新型的基于anti-HER2蒽环类的抗体-药物偶联物可诱导适应性抗肿瘤免疫并增强乳腺癌的PD-1阻滞D'Amico, Lucia; Menzel, Ulrike; Prummer, Michael; Muller, Philipp; Buchi, Melanie; Kashyap, Abhishek; Haessler, Ulrike; Yermanos, Alexander; Gebleux, Remy; Briendl, Manfred; Hell, Tamara; Wolter, Fabian I.; Beerli, Roger R.; Truxova, Iva; Radek, Spisek; Vlajnic, Tatjana; Grawunder, Ulf; Reddy, Sai; Zippelius, Alfred 分享 收藏 A molecular portrait of epithelial-mesenchymal plasticity in prostate cancer associated with clinical outcome (vol 38, pg 913, 2019)Stylianou, Nataly; Lehman, Melanie L.; Wang, Chenwei; Fard, Atefeh Taherian; Rockstroh, Anja; Fazli, Ladan; Jovanovic, Lidija; Ward, Micheal; Sadowski, Martin C.; Kashyap, Abhishek S.; Buttyan, Ralph; Gleave, Martin E.; Westbrook, Thomas F.; Williams, Elizabeth D.; Gunter, Jennifer H.; Nelson, Colleen C.; Hollier, Brett G. 分享 收藏 A molecular portrait of epithelial-mesenchymal plasticity in prostate cancer associated with clinical outcomeStylianou, Nataly; Lehman, Melanie L.; Wang, Chenwei; Fard, Atefeh Taherian; Rockstroh, Anja; Fazli, Ladan; Jovanovic, Lidija; Ward, Micheal; Sadowski, Martin C.; Kashyap, Abhishek S.; Buttyan, Ralph; Gleave, Martin E.; Westbrook, Thomas F.; Williams, Elizabeth D.; Gunter, Jennifer H.; Nelson, Colleen C.; Hollier, Brett G. 分享 收藏 分享 收藏 Antagonists of IGF: Vitronectin Interactions Inhibit IGF-I-Induced Breast Cancer Cell FunctionsKashyap, Abhishek S.; Shooter, Gary K.; Shokoohmand, Ali; McGovern, Jacqui; Sivaramakrishnan, Manaswini; Croll, Tristan I.; Cane, Gaelle; Leavesley, David I.; Soderberg, Ola; Upton, Zee; Hollier, Brett G. 分享 收藏 分享 收藏 Differential subcellular and extracellular localisations of proteins required for insulin-like growth factor- and extracellular matrix-induced signalling events in breast cancer progression乳腺癌进展中胰岛素样生长因子和细胞外基质诱导的信号传导事件所需的蛋白质的差异亚细胞和细胞外定位Plant, Helen C.; Kashyap, Abhishek S.; Manton, Kerry J.; Hollier, Brett G.; Hurst, Cameron P.; Stein, Sandra R.; Francis, Glenn D.; Beadle, Geoffrey F.; Upton, Zee; Leavesley, David I. 分享 收藏 分享 收藏 分享 收藏 
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