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Alavattam Sreedhara

pharmaceutical development, genentech inc., south san francisco, california 94080, united states

32H指数
87论文数
3.3K被引数
收录论文 37
发表时间
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Combination of Hydroxypropyl-Beta-Cyclodextrin and Trehalose for Improved Stability of Spray-Dried Monoclonal Antibodies羟丙基-β-环糊精与海藻糖组合用于提高喷雾干燥单克隆抗体的稳定性
errMolecular Pharmaceutics
IF4.5
err2025-07-10
err0
PREAI
errYu Tong Tam; Aadithya Kannan; Paroma Chakravarty; Minhthi Bui; William Mistler; Kevin Whang; Alavattam Sreedhara
err分享
err收藏
A single point mutation on FLT3L-Fc protein increases the risk of immunogenicity
errFRONTIERS IN IMMUNOLOGY
IF5.9
err2025-02-13
err0
errOAAI
errQin, Dan; Phung, Qui; Wu, Patrick; Yin, Zhaojun; Tam, Sien; Tran, Peter; Elsohly, Adel M.; Gober, Joshua; Hu, Zicheng; Zhou, Zhenru; Cohen, Sivan; He, Dongping; Bainbridge, Travis W.; Kemball, Christopher C.; Zarzar, Jonathan; Sreedhara, Alavattam; Stephens, Nicole; Decalf, Jeremie; Moussion, Christine; Ye, Zhengmao; Balazs, Mercedesz; Li, Yinyin
err分享
err收藏
Use of Closed System Transfer Devices (CSTDs) with ProteinBased Therapeutic Drugs-A Non-Solution for a Non-Problem?
errJOURNAL OF PHARMACEUTICAL SCIENCES
IF3.8
err2024-02-01
err2
PREAI
errFast, Jonas; Christian, Twinkle; Crul, Mirjam; Jiskoot, Wim; Nejadnik, M. Reza; Medina, Annette; Radwick, Allison; Sreedhara, Alavattam; Tole, Hugh
err分享
err收藏
Translatability of In Vitro Stress for Predicting Deamidation and Oxidation Biotransformation on Biotherapeutics
errANALYTICAL CHEMISTRY
IF6.7
err2023-11-30
err0
PREAI
errChu, Phillip Y.; Wang, Hui; Ross, Emily; Stephens, Nicole; Zhang, Hui-Min; Andersen, Nisana; Chan, Wayman; Shivva, Vittal; Crowell, Susan R.; Spiess, Christoph; Holder, Patrick G.; Agard, Nicholas J.; Ji, Chengjie; Chen, John; Sreedhara, Alavattam; Wang, Jianyong; Wu, Cong; Liu, Yichin; Tran, John C.
err分享
err收藏
High concentration formulation developability approaches and considerations
errMABS
IF7.3
err2023-05-16
err18
errOAAI
errZarzar, Jonathan; Khan, Tarik; Bhagawati, Maniraj; Weiche, Benjamin; Sydow-Andersen, Jasmin; Alavattam, Sreedhara
err分享
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Correction: End-to-End Approach to Surfactant Selection, Risk Mitigation, and Control Strategies for Protein-Based Therapeutics(vol 25, 6, 2023)
errAAPS JOURNAL
IF3.7
err2023-01-11
err1
errOAAI
errMorales, Annette Medina; Sreedhara, Alavattam; Buecheler, Jakob; Brosig, Sebastian; Chou, Danny; Christian, Twinkle; Das, Tapan; de Jong, Isabella; Fast, Jonas; Jagannathan, Bharat; Moussa, Ehab M. M.; Nejadnik, M. Reza; Prajapati, Indira; Radwick, Allison; Rahman, Yusra; Singh, Shubhadra
err分享
err收藏
Insights into ultra-low affinity lipase-antibody noncovalent complex binding mechanisms
errMABS
IF7.3
err2022-10-25
err10
errOAAI
errHecht, Elizabeth Sara; Mehta, Shrenik; Wecksler, Aaron T.; Aguilar, Ben; Swanson, Nathaniel; Phung, Wilson; Kelsoe, Ananya Dubey; Benner, W. Henry; Tesar, Devin; Kelley, Robert F.; Sandoval, Wendy; Sreedhara, Alavattam
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Physicochemical and biological impact of metal-catalyzed oxidation of IgG1 monoclonal antibodies and antibody-drug conjugates via reactive oxygen species
errMABS
IF7.3
err2022-09-24
err13
errOAAI
errGlover, Zephania Kwong; Wecksler, Aaron; Aryal, Baikuntha; Mehta, Shrenik; Pegues, Melissa; Chan, Wayman; Lehtimaki, Mari; Luo, Allen; Sreedhara, Alavattam; Rao, V. Ashutosh
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Stress Factors in Primary Packaging, Transportation and Handling of Protein Drug Products and Their Impact on Product Quality
errJOURNAL OF PHARMACEUTICAL SCIENCES
IF3.8
err2022-04-01
err22
errOAAI
errNarhi, Linda O.; Chou, Danny K.; Christian, Twinkle R.; Gibson, Scott; Jagannathan, Bharat; Jiskoot, Wim; Jordan, Susan; Sreedhara, Alavattam; Waxman, Lloyd; Das, Tapan K.
err分享
err收藏
Stress Factors in Protein Drug Product Manufacturing and Their Impact on Product Quality
errJOURNAL OF PHARMACEUTICAL SCIENCES
IF3.8
err2022-04-01
err24
PREAI
errDas, Tapan K.; Sreedhara, Alavattam; Colandene, James D.; Chou, Danny K.; Filipe, Vasco; Grapentin, Christoph; Searles, Jim; Christian, Twinkle R.; Narhi, Linda O.; Jiskoot, Wim
err分享
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Translational Approaches for Brain Delivery of Biologics via Cerebrospinal Fluid
errCLINICAL PHARMACOLOGY & THERAPEUTICS
IF5.5
err2022-02-23
err21
errOAAI
errSadekar, Shraddha S.; Bowen, Mayumi; Cai, Hao; Jamalian, Samira; Rafidi, Hanine; Shatz-Binder, Whitney; Lafrance-Vanasse, Julien; Chan, Pamela; Meilandt, William J.; Oldendorp, Amy; Sreedhara, Alavattam; Daugherty, Ann; Crowell, Susan; Wildsmith, Kristin R.; Atwal, Jasvinder; Fuji, Reina N.; Horvath, Joshua
err分享
err收藏
Metal Ion Interactions with mAbs: Part 2. Zinc-Mediated Aggregation of IgG1 Monoclonal Antibodies
errPHARMACEUTICAL RESEARCH
IF4.3
err2021-08-11
err11
PREAI
errMehta, Shrenik; Flores, Heather; Walters, Benjamin; Sreedhara, Alavattam
err分享
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A Comprehensive Assessment of All-Oleate Polysorbate 80: Free Fatty Acid Particle Formation, Interfacial Protection and Oxidative Degradation
errPHARMACEUTICAL RESEARCH
IF4.3
err2021-03-12
err31
PREAI
errDoshi, Nidhi; Giddings, Jamie; Luis, Lin; Wu, Arthur; Ritchie, Kyle; Liu, Wenqiang; Chan, Wayman; Taing, Rosalynn; Chu, Jeff; Sreedhara, Alavattam; Kannan, Aadithya; Kei, Pervina; Shieh, Ian; Graf, Tobias; Hu, Mark
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Optimizing Hydroxyl Radical Footprinting Analysis of Biotherapeutics Using Internal Standard Dosimetry
errJOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY
IF2.7
err2020-05-14
err11
PREAI
errGarcia, Natalie K.; Alavattam, Sreedhara; Deparalta, Galahad; Wecksler, Aaron T.
err分享
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Protein Stability and Photostability under In Vitro Vitreal Conditions - Implications for Long Acting Delivery of Protein Therapeutics for Ocular Disease
errPHARMACEUTICAL RESEARCH
IF4.3
err2020-04-26
err10
PREAI
errMantha, Neelima; Burra, Shalini; Rajagopal, Karthikan; Sreedhara, Alavattam
err分享
err收藏
Stress Factors in mAb Drug Substance Production Processes: Critical Assessment of Impact on Product Quality and Control Strategy
errJOURNAL OF PHARMACEUTICAL SCIENCES
IF3.8
err2020-01-01
err51
PREAI
errDas, Tapan K.; Narhi, Linda O.; Sreedhara, Alavattam; Menzen, Tim; Grapentin, Christoph; Chou, Danny K.; Antochshuk, Valentyn; Filipe, Vasco
err分享
err收藏
Challenges of Using Closed System Transfer Devices With Biological Drug Products: An Industry Perspective
errJOURNAL OF PHARMACEUTICAL SCIENCES
IF3.8
err2020-01-01
err30
errOAAI
errSreedhara, Alavattam; Zamiri, Camellia; Goswami, Sumit; Weiser, Sarah; Cram, Michael; Christian, Twinkle R.; Jagannathan, Bharat
err分享
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Identification of D-Amino Acids in Light Exposed mAb Formulations
errPHARMACEUTICAL RESEARCH
IF4.3
err2018-10-17
err2
PREAI
errBommana, Rupesh; Subelzu, Natalia; Mozziconacci, Olivier; Sreedhara, Alavattam; Schoneich, Christian
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err收藏
Fragmentation of a Monoclonal Antibody by Peroxotungstate
errPHARMACEUTICAL RESEARCH
IF4.3
err2018-09-25
err8
PREAI
errRathnayaka, Hasitha; Mozziconacci, Olivier; Sreedhara, Alavattam; Schoneich, Christian
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err收藏
Impurity investigations by phases of drug and product development
errTRAC-TRENDS IN ANALYTICAL CHEMISTRY
IF12
err2018-04-01
err31
PREAI
errOlsen, Bernard A.; Sreedhara, Alavattam; Baertschi, Steven W.
err分享
err收藏

研究方向

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合作期刊
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王慧 封面图
王慧 (Hui Wang)
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